38978 research outputs found
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Environmental Structure Science
No full textEnvironmental Structure Science is a theoretical framework that reconfigures environmental phenomena by focusing on environmental structure rather than individual components.
It separates emergence (conditions that allow a phenomenon to occur) from dominance (when the phenomenon determines system-level behavior), and analyzes both through environmental constraints such as barriers, capacities, and valves.
Environmental structures are defined by the coupled organization of time (reaction, transport, and transformation timescales), space (micro–macro arrangement, interfaces, phase separation), and constraints (physical, chemical, biological, and geochemical limits).
This framework treats trace components—including biomolecules, colloids, radionuclides, and PFAS—not as isolated substances, but as agents whose influence is defined by structured environmental conditions.
Environmental Structure Science provides a unifying perspective across Earth, planetary, and astrobiological environments.
環境構造学（Environmental Structure Science）は、環境現象を個別の物質や過程ではなく、環境構造を軸として再配置・再解釈する理論的フレームワークである。
本分野は、現象の発現（Emergence）と支配（Dominance）を明確に分離し、Barrier・Capacity・Valve などの制約条件とあわせて解析する。
環境構造は、時間構造、空間構造、および制約構造の結合として定義される。
生体分子、コロイド、放射性物質、PFAS などの微量成分は、構造化された環境の中で振る舞う存在として再定義される
Protocol for a scoping review on platelet rich fibrin in soft tissue applications
No full textThis article serves as an overview of the methodology that will be used to conduct a scoping review to assess the current literature available on platelet rich fibrin (PRF) in soft tissue applications
Latent Profiles of Parents’ Family-of-Origin Invalidation Experiences: Associations with Emotion Coping and Children's Prosocial Behavior
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KFX: Minimal Core Formal System
No full textA minimal constrained-path formal system illustrating rigidity induced by global admissibility constraints.
This project serves as a reference implementation and discussion hub
Illuminating the intersectional experiences of individuals living with eating disorders and disordered eating: The in/accessibility of treatment services
No full textEating disorders (EDs) and disordered eating behaviours (DEBs) significantly impact mental and physical health and are associated with high morbidity and mortality worldwide. In Canada, EDs affect an estimated one million people, while DEBs likely affect even more individuals, though prevalence remains under-measured. Many people with EDs/DEBs do not meet strict diagnostic criteria, and among those who do, only a minority are able to access appropriate care. Barriers to diagnosis and treatment include stigma, stereotypes, and limited equity-oriented and inclusive healthcare practices. These challenges are compounded for individuals who occupy marginalized social positions, who may face increased risk of EDs/DEBs while remaining under-represented in research and poorly served by existing treatment models.
This qualitative research project aims to explore and illuminate the lived experiences of individuals with EDs/DEBs who experience marginalization in accessing diagnosis and treatment. By centering perspectives that are often excluded from eating disorder research, this study seeks to identify structural, social, and systemic factors shaping access to care and to inform more inclusive, responsive, and equitable approaches to ED/DEB diagnosis and treatment
Associations between Anticipated, EMA- and Laboratory-Derived Alcohol Stimulation, Sedation, and Reward
No full textPrenatal Stress and Child Development in Low-Middle Income Countries: Linking Maternal Hair Cortisol to Childhood Mental Health and Behavioural Outcomes
No full textResearch has shown the importance of prenatal influences on child development, identifying it as a critical window of development; however, less is known about how the mother's chronic physiological stress impacts children’s longer term developmental outcomes. While studies within high-income countries have indicated negative impacts of maternal stress on the development and wellbeing of offspring due to extreme stressors during pregnancy, the impacts of chronic physiological stress remain to be clarified. Recent methodological advances in the use of hair cortisol as a biomarker of stress now make it possible to unobtrusively obtain objective biomarkers of chronic stress at scale in prenatal samples.
The current study aims to leverage this possibility to further understanding of the effects of prenatal stress on child developmental outcomes by linking maternal stress, through reported stress alongside hair cortisol concentrations and their ratio to cortisone, with early childhood outcomes. Having data from birth, and at 3-6 and 18 months will allow us to examine the correlations between hair cortisol and its ratio with cortisone during pregnancy and early child development. We will examine the raw associations, associations adjusted for potential confounders, and associations adjusted for other covariates which have been shown to impact child development, to illuminate the unique effects of prenatal physiological stress exposure
When MRI Is Not Enough: Moyamoya Disease Presenting with Recurrent Transient Ischaemic Attacks and Seizures in a 12-Year-Old Boy from Western India
No full textThis project contains an archived pediatric clinical case report prepared in 2017 and shared for educational and open-science purposes. The report is made publicly available to support clinical training, diagnostic reasoning, and global health education