Proceedings in Obstetrics and Gynecology
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Pregnancy Predictors of Health
Pregnancy Predictors of Health, University of Iowa Obstetrics and Gynecology Postgraduate Virtual Conference, November 5, 2021Poster Presentation
Amenorrhea and pituitary human chorionic gonadotrophin production in a 38-year-old presenting as pregnancy of unknown location: case report and review of literature
Background: Amenorrhea and extraplacental production of serum human chorionic gonadotropin (hCG), particularly in young women, can mimic a pregnancy of unknown location. Elevated serum hCG in the absence of pregnancy can pose a diagnostic dilemma and has led to potentially harmful and unwarranted interventions including chemotherapeutic agents like methotrexate or have led to delay in necessary medical interventions in women. We report a case to demonstrate that amenorrhea and extraplacental human chorionic gonadotropin (hCG) production in young women can mimic a pregnancy of unknown location. Furthermore, we performed a critical review of literature on pituitary hCG production. Case: A 38-year-old woman with a diagnosis of Silver-Russell syndrome, a unicornuate uterus, history of right oophorectomy for a benign serous cystadenoma and a desire for pregnancy presenting with a provisional diagnosis of pregnancy of unknown location.After performing a thorough review of history, physical examination, ultrasound exams, and a review of hormone analysis [including hCG, Tumor markers, Follicle-stimulating hormone (FSH), Luteinizing hormone (LH), Anti-Mullerian Hormone (AMH), Estradiol (E2) levels], we confirmed the diagnosis of premature ovarian insufficiency and pituitary hCG production. Conclusions: In women, serum levels of hCG may increase with age, and are not always an indicator of pregnancy. Therefore, it is imperative to interpret false-positive test results and rule out the extraplacental production of hCG. This will help prevent unnecessary surgical procedures and treatment, including chemotherapy
New Technologies in Obstetrics and Gynecology: Poster Presentations
New Technologies in Obstetrics and Gynecology, University of Iowa Obstetrics and Gynecology Postgraduate Conference, Hyatt Regency Coralville, Coralville, IA. November 4, 2022Poster Presentation
How did the COVID-19 Pandemic impact self-reported cancer screening rates in 12 Midwestern states?
Objective: In the early months of the COVID-19 pandemic, the U.S. healthcare system reallocated resources to emergency response and mitigation. This reallocation impacted essential healthcare services, including cancer screenings. Methods: To examine how the pandemic impacted cancer screenings at the population-level, this study analyzes 2018 and 2020 Behavioral Risk Factor Surveillance System (BRFSS) data to estimate the change in the proportion of eligible adults reporting a recent cancer screen (mammogram, pap smear, colon/sigmoidoscopy, blood stool test). All analyses accounted for response rates and sampling weights, then explored differences by gender and rurality across 12 Midwestern states. Results: We found that the proportion of adult women completing a mammogram declined across all states (-0.9% to -18.1%). The change in colon/sigmoidoscopies, pap smears, and blood stool tests were mixed, ranging from a 9.7% decline in pap smears to a 7.1% increase in blood stool tests. Declines varied considerably between states and within states by gender or metro/urban/rural status. Conclusions: The COVID-19 pandemic led to delayed breast, cervical, and colorectal cancer detection services. Policymakers should aim to advance cancer control efforts by implementing targeted screening initiatives
Look before you LEEP: patient reported pain with IV sedation vs local analgesia
Objective: Examine the effectiveness of IV sedation in addition local analgesia compared to local analgesia alone for LEEP pain management. Methods: This quality improvement project surveyed 89 patients who underwent a LEEP procedure: 26 in the local only group and 63 in the IV + local group. Patients completed a visual analog scale and pain survey immediately following their LEEP. Results: The local analgesia + IV sedation group reported a lower average pain score compared to the local analgesia only group (2.4 ± 2.2 v 3.6 ± 2.7). However, this was not statistically significant, p 0.47. Patients found it was helpful to know what to expect prior to the LEEP and utilized various means of pain relief in addition to the primary treatments assessed. Conclusions: There is a need for high quality trials to determine best practices of pain management
COVID-19 expands food insecurity disparities among rural, high-risk obstetrics patients
Objective: To compare rural and urban food insecurity in a high-risk obstetrics population prior to and during the COVID-19 pandemic. Methods: Utilizing convenience sampling of high-risk obstetrics patients, validated survey questions assessed self-reported food insecurity from March - October 2019 (pre-COVID-19) and March - October 2020 (COVID-19). Chi-squared analysis compared food insecurity between these two periods and among patients living in rural vs. urban counties.Results: A total of 1089 (pre-COVID-19) and 1246 (COVID-19) screenings were completed. Compared to 2019, the prevalence of food insecurity in 2020 was significantly higher from March-June only (7.8% pre-COVID-19 vs. 11.4 % COVID-19, p=0.04). Despite pre-COVID-19 similarity, rural patients reported significantly higher food insecurity prevalence during COVID-19 than urban counterparts (12.9% rural vs. 8.2% urban, p<0.01). Conclusions: The COVID-19 pandemic was associated with a disproportionate effect on food insecurity among rural patients with high-risk pregnancies. Rural health systems and agencies should explore proactive screening and intervention efforts to mitigate the adverse, downstream health effects of food insecurity
Serum concentration of matrix metalloproteinase-1 in patients with preterm labor compared to gestational age matched controls
Ductal-cutaneous fistula secondary to recurrent Bartholin’s cysts: a case report
Background: Disorders of the Bartholin’s duct and gland, including cyst and abscess formation, account for 2% of gynecologic visits annually. An uncommon complication of a Bartholin’s duct or gland abscess is fistula formation. Literature has described cases of recto-Bartholin’s and recto-vaginal fistulas. Case: We present a case of fistula development between the perineum and the Bartholin’s duct and gland. The patient was successfully managed with fistulectomy and Bartholin’s gland excision. Conclusion: Though fistula formation is a rare complication of Bartholin’s duct and gland pathology, investigation is warranted. A ductal-cutaneous fistula is possible in the setting of recurrent cysts located beyond the vaginal introitus. The best method of prevention is appropriate execution of a marsupialization. Complete removal of the fistulous tract and Bartholin’s duct and/or gland can result in resolution of symptoms
New Technologies in Obstetrics and Gynecology: Presentations
New Technologies in Obstetrics and Gynecology, University of Iowa Obstetrics and Gynecology Postgraduate Conference, Hyatt Regency Coralville, Coralville, IA. November 4, 2022 Presentation