4919 research outputs found

    Performance of residential property investment returns in an emerging metropolitan area. The awareness, use and gender inequality

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    This study assessed the performance of residential property investment returns. To ascertain the awareness, use, and gender inequality in the usage of residential performance data by investors. The paper focuses on risk-return features of the tenement, two and three-bedroom property for investment purposes, in order to improve the understanding of the property market mechanism in Kano metropolis, Nigeria. Unraveling empirically risk-return features of residential property in the metropolitan area is unclear hence the speculative decision on residential investment is widespread. Quantitative research was employed using a questionnaire survey to obtain primary data on annual rental and capital values of residential properties from branch managers of estate firms. This data was afterward transformed into total returns and put to Phillip-Perron unit root test (stationarity). The study utilized both descriptive and inferential statistical techniques for analysis. Findings from the study show that total returns for residential property range from 6.99% to 14.44% with risk-return ranging from 20.92% to 51.54% within the property market, Badawa/GRA property has the lowest risk features hence the most secured location for residential investment, the paper also unveils that gender inequity in the usage of residential property investment performance data is high against women. It is on these findings that the study recommended Badawi/GRA property market for risk-averse investors, persistent sensitization program and incentives (reduction in service charge) targeting women in the property market is encouraged.</p

    Validating integrated environmental solutions software for air temperature of a typical Malaysian recessed wall façade office building

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    Technological advances have assisted in the development of modern software tools which can be used to assess and improve the energy efficiency of a building at the early stage of conceptual design. However, this study aims at validating the accuracy of one of the paramount building simulation software Integrated Environmental Solutions - Virtual Environment (IES-VE), widely used today. The methodology of this study involves physical measurements and simulation exercises. A longitudinal physical measurement was carried out using HOBO ware U-12 in 5 different points of the room space from 18th October to 4th December 2016. But, for validation, a critical atmospheric day (21st November 2016) was selected for the comparison. The room air temperature was first measured before comparing it to the simulated air temperature obtained from IES&lt;VE&gt;. After several analyses, the comparison of the measured room air temperature and simulation results showed similarity, discrepancy, closeness, significance, and accuracy. The investigation findings revealed a percentage discrepancy of 11.03%, which is less than the threshold of 20% between the measured and simulated air temperature of the case study model. Other findings show that: R2 = 0.98, MBE = 0.8, °C and RMSE = 1.70°C are all within the acceptable values of significance between the two data. These results signify that IES-VE is valid, accurate, and applicable for this study’s further Building Performance Simulation (BPS).</p

    Spatial distribution of COVID-19 in Ethiopia - geospatial analysis

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    Background: COVID-19 was the devastating worldwide public health problem in recent years. COVID19 disease affecting large populations in different continents of the world starting on 11 March 2020.This study will be useful to give information on geographical surveillance of COVID-19 in Ethiopia, to know regions of high or low rates of COVID 19, to give evidence as baseline data for future research on COVID-19 in Ethiopia, and to predict the prevalence of COVID-19 from the untested population in different regions of Ethiopia using the art geospatial techniques.&nbsp;Methods: We have used secondary data collected from March 13, 2020, to November 23/ 2021 From COVID19 – Ethiopia - Ethiopian Health Data. ArcGIS 10.3 and SaTscan software were used for spatial analysis and geographical analysis respectively.&nbsp;Results: A high prevalence of COVID-19 was found in Addis Ababa (67.36%) and Oromia (13.85%).&nbsp;Spatial autocorrelation analysis indicated that the spatial distribution of COVID-19 is nonrandom (Moran’s Index: 0.134297, P-value: 0.052384).&nbsp;In spatial scan statistical analysis, eight clusters were identified and the higher rates of COVID-19 were observed in the Afar (RR= 1.80, p&lt;0.001) and Addis Ababa (RR= 50.33, p&lt;0.001) regions.&nbsp;Conclusion: The spatial distribution of COVID-19 cases in Ethiopia was not random.&nbsp;Hot spot research revealed a significant prevalence of COVID-19 patients in the Addis Ababa, Dire Dawa, Harari, and Oromia regions. For the reduction of COVID-19 infections in Ethiopia, preventative and control activities should be extended to high-risk locations.</p

    Effects of Extraction Temperature and Particle Size on Quality of Edible Oil from Podocarpus Falcatus Seed by Aqueous Method, Ethiopia

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    Objective: The kernel from Podocarpus falcatus has potential for the production of edible oil. The oil is currently extracted using a traditional inefficient method for the purpose of household consumption. The objective of this study was to investigate the effects of particle size and extraction temperature on the yield and quality of oil extracted from P. Falactus seeds by the aqueous method. The experiment was carried out in a completely randomized design that comprised of three aqueous temperatures (70, 80, and 900C) and three particle sizes (0.25, 0.50, and 0.75mm).&nbsp;Results: The maximum oil yield in this study was obtained at 22.29 and 22.38±2.10% at an extraction temperature of 70°C and the particle size of 0.5mm respectively. Particle size and oil yield have a correlation in that higher extraction were obtained (25%) as the particle size decreased. The particle size and temperature interaction had a positive effect on yield and maximum oil yield (25.25%) was obtained by the combination of 0.25mm particle size and 70°C. The peroxide, iodine, and saponification values were obtained with an acceptable range by the combination of 0.25mm and within the acceptable limit of edible oil 70°C. Yield and oil quality were influenced by extraction particle size and temperature.</p

    Detoxification: We need necessary endogenous pathways

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    Toxins are substances that burden the body and can lead to disease. They either originate from the body’s metabolism or were supplied from outside. The organism is forced to transport these substances out if it wants to maintain its integrity. There are many ways to do this that we are rarely aware of. These will be pointed out. It is of great importance that we do not suppress them, but activate them. The know-how necessary for this should be known by every person.</p

    A first comprehensive look at the order-disorder nature of RTK KIT native and carcinogenic targets

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    Receptors Tyrosine Kinases (RTKs) act as sensors for extracellular ligands, the binding of which triggers dimerization, activation, and autophosphorylation of specific tyrosine (Y) residues in the Cytoplasmic Domain (CD). This leads to the recruitment and activation of multiple downstream signaling proteins, which regulate various aspects of cellular physiology.&nbsp;</p

    The effects of thymoquinone and cytozine arabinoside on apoptosis and cell proliferation in acute myeloide leukemia

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    Purpose: The aim of this study was to investigate the effects of a chemotherapeutic agent Cytosine Arabinoside (Ara-C) and a natural anticancer agent of Thymoquinone (TQ) on apoptosis and cell proliferation of AML cell lines (Kasumi-6) both alone and in combined form.Material and method: Kasumi-6 AML cells were treated with three different doses of Ara-C (0.1, 0.5 and 1 µmol) and TQ (25, 50 and 100 µM) for 48 and 72 hours incubations. After Annexin V and Propidium Iodide (PI) staining, apoptosis, viability, and cell proliferation were evaluated for each group in flow cytometry.Results: As a result, AML cell lines showed a statistically significant difference in a single treatment of the active substances. Their combined treatment showed an increase in apoptosis and a decrease in viability in both groups at 48 and 72 hours incubation times (p &lt; 0.001). In each group, it was observed that apoptosis was increased and viability was decreased and consequently cell proliferation was suppressed.Conclusion: Ara-C was used for the first time in this study with TQ in AML. It was determined that the combined use of TQ and Ara-C did not have a synergistic effect on apoptosis.</p

    Design a simulating lung in 36h or less

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    Background: During the COVID health crisis, intensive care units were quickly overwhelmed and had to call for help. The only solution was to call for this help among nurses, nursing auxiliaries, and physicians that were normally not working in the ICU units (consultations, operating room, medical units). These people needed mechanical ventilation courses before beginning their job in the ICU unit.Simulation appeared to be the best solution because of its safety and educational effectiveness.&nbsp;Approach: We developed an artificial lung during the 36 hours innovation marathon Crunch Maker Camp 2021. It included three main settings which were lung compliance, airways resistances, and diaphragmatic inspiratory trigger. These parameters seemed to be essential for us in order to simulate the mechanical ventilation characteristics of a COVID lung. The simulator was entirely made of physical components.Evaluation: The team composed of engineers and intensive care medical instructors developed the first proof of concept of the artificial lung. The different controllable modules were able to adjust compliance, and resistance on the respirator, and an inspiratory trigger was efficient. They reflected correctly a normal or a COVID lung, simulating a patient on a ventilator.The simulator was presented to the jury and after deliberation, the teams’ work was rewarded with the first innovation prize.Reflection: We designed a controlled simulation for COVID respiratory issues; the artificial lung was rewarded during this innovation marathon Crunch Maker Camp 2021. This allowed us to improve the simulator and we plan to start using this tool during training sessions soon. We will then measure Pedagogic impact, focusing on long-term memorization.</p

    Examination of Paraffin Sections of Different Rainbow Trout (<i>Oncorhynchus mykiss</i>) Tissues by Light and Scanning Electron Microscope

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    The current study aimed to highlight histopathological findings in paraffin block sections of the liver, gill kidney, and pyloric cecum of rainbow trout (Oncorhynchus mykiss) by different imagining devices such as Scanning Electron (SEM) and Light Microscope (LM). To determine the performance of different imagining methods two different thickness paraffin sections such as 5 and 15 µm about various rainbow trout tissue were prepared for imagining different devices. That sections were imagined by SEM and LM, both sections including 5 and 15 µm were imagined by SEM while just 5 µm was an image by LM. In LM imagining, it was detected that hydropic degeneration and vacuole formations in the liver hepatocytes of fish, as well as hyperplasia in bile ducts. Lamellar epithelial cell hyperplasia/hypertrophy was mild and histopathological findings such as secondary lamellar elevation and edema were more severe in rainbow trout gills. Glomerular atrophy/hypertrophy was moderately detected in the kidneys and hydropic degeneration of tubular epithelium was more severe. No degeneration or necrosis was observed in the lamina epithelium of the pyloric cecum. In SEM imagining of different thickness paraffin sections, cartilage and secondary lamellar structure in the gills, glomerulus, and Bowman’s capsule structure in the kidneys, and the structure of the pyloric cecum was observed. In the SEM imaging of the paraffin block sections of hepatocytes of the liver, the cell nuclei were determined, and also the grooves in the cytoplasm were thought to be vacuoles. As a consequence, the structural elements of the organ had higher clarity in SEM imaging from paraffin block sections, but the histopathological alterations remained unclear. As a result, SEM imaging of fish tissue is more suited for seeing tissue architecture, although LM imaging is better suited for determining and scoring histopathological variations.</p

    Drag force through gases and plasma

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    The drag force in a gas (previously derived by Stokes and Rayleigh) is derived by means of the molecular kinetics (transport equation of the momentum). Two regimes of resistance to motion are identified, governed by the relation of the velocity to the thermal (molecular) velocity. They correspond to the molecular movement, for small velocities, or to the hydrodynamic motion for high velocities. In the former case sound waves are not excited, and energy is dissipated by viscosity (friction), while in the latter case the energy is dissipated by the excitation of the sound waves. Also, the treatment is applied to the plasma. It is shown that in usual plasmas it is unlikely that the body motion excites plasmons.&nbsp;</p

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