RocScholar (Rochester Regional Health)
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The Safety And Efficacy Of Dupilumab In A Real-World Clinical Setting: The RAPID Asthma Prospective Registry
No full textTemporal trends and procedural safety of mitral valve transcatheter edge to edge repair in patients with previous CABG
No full textIntroduction: Mitral Valve Transcatheter Edge-to-Edge Repair (M-TEER) is a minimally invasive procedure for patients with symptomatic mitral regurgitation. Its outcomes in patients with a history of coronary artery bypass grafting (CABG) remain unclear.
Methodology: We analyzed data from the Nationwide Inpatient Sample, using ICD-10-CM codes for M-TEER and CABG. Primary outcomes included in-hospital all-cause mortality and periprocedural cardiac complications. Inverse probability of treatment weighting was employed to compare M-TEER patients with or without prior CABG.
Results: From January 2016 to December 2020, we identified 48,835 M-TEER cases in the U.S. with 9,655 patients (19.78%) having a prior CABG. These patients were older and had more comorbidities. M-TEER procedures increased over the study period, including those with prior CABG (2,145 in 2016 vs. 2,682 in 2020). Adjusted analysis showed no significant difference in in-hospital mortality between patients with and without prior CABG [adjusted odds ratio (aOR) 0.85, 95% confidence interval (CI) 0.85-1.32, p = 0.47]. However, patients with prior CABG had lower odds of periprocedural cardiac complications [aOR 0.72, 95% CI 0.59-0.87, p = 0.001].
Conclusions: M-TEER appears safe for patients with prior CABG, showing no adverse peri-procedural outcomes compared to those without CABG. Despite more comorbidities, M-TEER remains a safe option for these patients
Steroid stewardship in allergy/immunology: An opportunity for improved clinical outcomes
No full textNavigating the Digital Frontier: Medicine in the Modern Era
No full textNavigating the Digital Frontier: Medicine in the Modern Era. Dr. Farhad Nasar, Medical Director, Health Informatics, Program Director, Clinical Informatics Fellowship; Dr. Tamer Salhab Altamimi, Fellow, Clinical Informatics; Dr. Mostafa Balboul, Fellow, Clinical Informatics
Objectives: Trace the historical development of healthcare technology, highlight key milestones, and discuss their impact on patient care and medical practice Examine human-computer interaction principles, analyze AI\u27s role in healthcare, and identify and mitigate biases in technology use Review emerging trends in healthcare technology, discuss potential innovations and their implications, and encourage critical thinkin
Resident Research Projects, 2025
No full textResident Research Projects, 2025
Herpes Zoster Ophthalmicus with Encephalitis: A Review of Literature. Kellyn Wilkes, M.D., PGY-3, Chief Resident
Overcoming Severe Cytokine Release Syndrome: Successful Rituximab Desensitization in IVLBCL. Adithya Nagendran, PGY-1
Protective Effects of Emodin Against Gut Microbiota-Induced Oxidative Stress and Colon Cancer Pathogenesis. Yousef Waly, M.D., PGY-1
Association Between Rate of Hypernatremia Correction and Mortality: A Retrospective Cohort Study. Hyun Lee, M.D., PGY-3, Chief Residen
Socioeconomic Disparities in the Care of for High-Risk Pulmonary Embolism in the United States, 2016 to 2020
No full textThere are limited data on the impact of socioeconomic factors on the management and outcomes of high-risk acute pulmonary embolism (PE). Using the National Inpatient Sample (NIS) from 2016 to 2020, we identified adult (≥ 18 years) admissions with high-risk PE (defined as PE with one of: cardiogenic shock, vasopressor use, or cardiac arrest). Socioeconomic determinants included sex, race, insurance payer, and economic status. Outcomes of interest included in-hospital mortality, rates of mechanical circulatory support (MCS) and definitive PE interventions, hospitalization duration, and hospitalization costs. Among 21,521 high-risk PE hospitalizations (median age 65 years, 53% male, 64% white race), the socioeconomic variables remained stable during the 5-year period. MCS utilization was 4%, with lower rates of utilization in Medicare and Medicaid beneficiaries, uninsured admissions, and those from the lowest income quartile (all p \u3c 0.05). Racial minorities, those from lower economic status, and uninsured admissions received advanced PE interventions less frequently. There did not appear to be notable sex disparities in use of advanced PE therapies. Overall, in-hospital mortality was 50%, with higher adjusted in-hospital mortality in female, African American, Hispanic, uninsured, and economically disadvantaged individuals. In conclusion, significant inequities in in-hospital mortality, mechanical circulatory support, and definitive pulmonary embolism therapy utilization persist among high-risk PE hospitalizations in the United States based on sex, race, income, and insurance status
RDTA-05 Bevacizumab for Radiation-Induced Brain Necrosis: A Systematic Review of Randomized Controlled Trials and Cohort Studies
No full textRipretinib versus sunitinib in imatinib-resistant gastro-intestinal stromal tumor with KIT Exon 11 mutations: A systematic review and meta-analysis
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