OpenWorks @ MD Anderson
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4211 research outputs found
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CRISPR/Cas9-Mediated Genome Editing of Y705 Residue of STAT3 for Genetic Validation of Small Molecule Inhibitors In Breast Cancer Cells
Get PDFhttps://openworks.mdanderson.org/sumexp23/1122/thumbnail.jp
Analysis and Prediction of Patient Survival After Radiotherapy For Liver Cancer Based On Volumetric Segmental Response and Clinically Relevant Factors
Get PDFhttps://openworks.mdanderson.org/sumexp23/1121/thumbnail.jp
Critical Thinking in Student Nurses
Get PDFJolly Joseph, Jeena Sibi Issac, and Lakeisha Day pictured. Nocturnal Teamhttps://openworks.mdanderson.org/aprn-week-23/1016/thumbnail.jp
GitHub Workshop
Get PDFJanuary 27, 2023
John Wood, MS Senior Applications Systems Analyst, Enterprise Development and Integration, The University of Texas MD Anderson Cancer Center
Austin Castelo, BS Associate Systems Analyst, Imaging Physics Department, The University of Texas MD Anderson Cancer Center
Part I: GitHub Basics - for faculty, investigators, future, and active GitHub users
Part II: Using Institutional GitHub – for active and future GitHub users
Part III: GitHub Demo, Interactive Discussion, and Troubleshooting – for active and future GitHub usershttps://openworks.mdanderson.org/igct_workshops/1005/thumbnail.jp
Colorful Earth, 2023
No full textArtist: Leslie M. Cavazos
Materials: Using recyclable glass, metal, and plastic. Preserved dried flowers added. These items will be held together by paint, glue, and canvashttps://openworks.mdanderson.org/recycledart2023/1000/thumbnail.jp
Out of Gas, 2023
No full textArtist: Dennis R. Winters II
Materials: Metal gas cylinder
An empty gas cylinder turned into a reusable Jack O\u27 Lantern.https://openworks.mdanderson.org/recycledart2023/1005/thumbnail.jp
Professional Education Toolkit for Management of Cancer Survivors
No full texthttps://openworks.mdanderson.org/edwk23/1002/thumbnail.jp
A Meta-Narrative Review of RUNX1-RUNX1T1 and its Relativity to CBF Disruption Within the Adult Population
Get PDFAcute Myeloid Leukemia (AML) is an aggressive subgroup of leukemias developed from a deviant hematopoietic stem cell, prevented from differentiating into a mature cell. Additionally, core binding factor (CBF) is disrupted by the translocation of chromosomes 8 and 21. This balanced translocation generates the RUNX1-RUNX1T1 fusion gene on the derivative chromosome 8, resulting in t(8;21)(q22;q22.1). These events cause a blockage of hematopoietic stem cell differentiation and ultimately lead to leukemia transformation (Beghini, A. 2019). Using Fluorescence in situ hybridization (FISH) and Karyotyping, molecular translocation can be detected, visualized, and associated with chromosomes 8 and 21 [t(8;21)(q22;q22)]. Furthermore, this study will investigate how gene fusion and translocation disrupt CBF for the purpose of understanding how AML is diagnosed and treatment. To address this, we conducted a meta-narrative review of the number of articles that correspond to each sub-theme of the approach to AML in the context of RUNX1-RUNX1T1 fusion gene, including the utilization of treatments, its detail on correlation to CBF complex, how the research method was depicted, limitations, audience, technology, and treatment. One of the most important aspects of the study was the understanding of genetic abnormalities and the use of genetic analysis in developing future treatment strategies for leukemia. The correlation of RUNX1-RUNX1T1 gene generated on the derivative chromosome 8 will result in t(8;21)(q22;q22.1), a balanced translocation.https://openworks.mdanderson.org/rmps/1006/thumbnail.jp
Library News June 2023
Get PDFCiting Preprints in Manuscripts and Grants “Toxicity” vs. “Toxic Effect”: Which Is Better? Microsoft Editor: Intelligent Writing Assistance LGBTQIA+ eBooks, Audiobooks, and Resourceshttps://openworks.mdanderson.org/rmlnews23/1003/thumbnail.jp
The Impact of Online Self-Scheduling Platform Optimization on Patient Directed Access to Screening Mammography Appointments During the COVID-19 Pandemic
Get PDFScreening mammography is a low complexity exam for scheduling coordination. Optimization of our online self-scheduling platform with EHR integration resulted in a 26-fold increase in patient utilization and a 16-fold reduction in patient access team hands-on screening mammogram scheduling engagement.https://openworks.mdanderson.org/acif24/1002/thumbnail.jp