University of La Rioja

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    Challenges Psoriasis and Its Impact on Quality of Life: Challenges in Treatment and Management

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    Psoriasis, a chronic inflammatory disease affecting approximately 3% of the global population, presents complex challenges that extend beyond its physical manifestations. This comprehensive review examines the multidimensional impact of psoriasis on patients' lives, encompassing physical, psychological, and social aspects. We analyze current therapeutic approaches, from traditional systemic treatments to cutting-edge biological therapies and emerging oral medications, evaluating their efficacy, limitations, and accessibility. The review explores how disease severity correlates with quality of life measures and psychological burden, noting the high prevalence of depression (20%), anxiety (21%), and suicidal ideation (0.77%) among affected individuals. However, emerging evidence suggests that clinical severity, as measured by PAST or BSA, does not always correlate with the psychoemotional burden experienced by patients, highlighting the need for a more comprehensive assessment of disease impact. We discuss the evolution of treatment strategies, highlighting recent developments in targeted therapies, including JAK inhibitors, particularly selective TYK2 inhibitors, and PDE4 inhibitors, which offer promising alternatives to traditional treatments. Additionally, we examine the role of various assessment tools and quality of life measures in evaluating treatment outcomes. The analysis emphasizes the need for a holistic approach to patient care that integrates medical interventions with psychological support, addressing both the visible and invisible burdens of the disease. This review underscores the importance of personalized treatment strategies that consider not only clinical efficacy but also patient preferences, accessibility, and long-term safety profiles

    The Role of Textbooks in Shaping EFL Learners’ Cultural Mental Lexicon

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    This study aims to: (i) explore the number and lexical category of cultural words in an EFL textbook used by 44 4th ESO students; (ii) analyse the number of types produced by these informants in response to a task based on three culturally framed stimulus words (Culture, Traditions, Celebrations); and (iii) investigate the relationship between textbook input and students' word production at the start and end of the academic year. Results show alignment between student responses and textbook content, with increased production of cultural words by the end of the year. These findings suggest that their EFL textbooks and instruction influence learners' cultural knowledge. Supporting Agencies This article is part of a research project funded by the Ministry of Science, Innovation and Universities of the Government of Spain and the European Union (FEDER funds) [Project code: PGC2018-095260-B-100].Cette étude vise à : (i) explorer le nombre et la catégorie lexicale des mots culturels dans un manuel d’ALE utilisé par 44 étudiants du  4e Cours de la ESO (Éducation Secondaire Obligatoire) ; (ii) analyser le nombre de types produits par ces informateurs en réponse à une tâche PdLex basée sur des mots stimulus culturellement encadrés (Culture, Traditions, Célébrations) ; et (iii) étudier la relation entre l’apport des manuels scolaires et la production de mots des étudiants au début et à la fin de l’année scolaire. Les résultats montrent un alignement entre les réponses des élèves et le contenu des manuels scolaires, avec une augmentation de la production des mots culturels á la fin de l’année. Ces résultats suggèrent que les manuels et l’enseignement influencent les connaissances culturelles des apprenants. Cette étude vise à : (i) ex Organismes de soutien  Cet article fait partie d’un projet de recherche financé par le Ministère de la Science, de l’Innovation et des Universités du gouvernement espagnol et par l’Union européenne (fonds FEDER) [Code du projet : PGC2018-095260-B-100].Este estudio tiene como objetivos: (i) explorar el número y la categoría de las palabras culturales que aparecen en un libro de texto de inglés utilizado por 44 estudiantes de 4.º de ESO; (ii) analizar el número de tipos producidos en respuesta a una tarea basada en tres palabras estímulo culturales (Cultura, Tradiciones, Celebraciones); (iii) investigar la relación entre el contenido del libro y la producción de palabras al inicio y al final del curso. Los resultados muestran una alineación entre las respuestas de los estudiantes y el contenido del libro, aumentando la producción de palabras culturales al final del año. Estos hallazgos sugieren que los libros de texto y la instrucción influyen en el conocimiento cultural de los estudiantes. Agencias de apoyo Este artículo se enmarca en un proyecto de investigación financiado por el Ministerio de Ciencia, Innovación y Universidades del Gobierno de España y la Unión Europea (fondos FEDER) [Ref. del proyecto: PGC2018-095260-B-100]

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