International Journal of Science, Technology & Management (IJSTM)
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Antibacterial Activity Of Lime Peel (Citrus Aurantifolia (Christm.) Swingle) Ethanolic Extract Against Skin Infection Bacteria (Propionibacterium Acnes And Staphylococcus Epidermidis)
No full textThe skin is the outermost part of the body that serves as a protective body. In addition to protecting the skin of the face, it also acts as a beautifier. The main problem with facial skin is inflammation of the skin, which can cause acne. Bacteria like Propionibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa can cause acne on the face. Prolonged use of antibiotics as therapy against acne will cause a new problem, namely resistance to antibiotics. Lime peel has many uses, especially as an antibacterial, which makes it a good candidate for use as an antibacterial agent in acne treatment. The goal of this study was to find out if the etTMhanolic extract of lime peel could kill bacteria like Propionibacterium acnes and Staphylococcus epidermidis. The research method used the Kirby-Bauer method and the Streaking methods to analyze the minimum inhibitory concentration and minimum bactericidal concentration. The results showed MIC at a concentration of 1 mg/mL for each bacterium, while MBC at a concentration of 40 mg/mL in Propionibacterium acnes and 50 mg/mL in Staphylococcus epidermidis. The conclusion is that the extract of lime peel in ethanol can kill bacteria.
 
Immunostimulant Effect Test Of Curcuminoid Extract From Turmeric Rhizome (Curcuma Domestica Val.) In VCO On Rats Induced Cyclophosphamide Againts An Increasing Total Leukocytes And Leukocyte Differential
No full textTurmeric (Curcuma domestica Val.) is a traditional Indonesian plant that has many benefits. Curcuminoids are turmeric compounds known to have effects as immunomodulators and have been proven in several in vivo tests. Immunosuppressive drugs such as cyclophosphamide are widely given to improve clinical symptoms in autoimmune patients and cancer treatment which can cause susceptibility to infection.Therefore,this study aimed to determine the immunostimulating effect of curcuminoid extract from turmeric rhizome on cyclophosphamide-induced white rats. Proof of the immunostimulating effect of curcuminoid extracts was by testing the total leukocytes and leukocytesdifferential. The test results showed that curcuminoid extracts of 1 mL, 0.5 mL, and 0.25 mL increased total leukocytes and leukocyte differential (lymphocytes, neutrophils, monocytes, basophils, eosinophils) with a significant difference (p<0.05) to the Na group CMC 0.5% as a negative control. Therefore, curcuminoid extract had the potential to have an effect as an immunostimulant.
The test results showed that curcuminoid extracts of 1 mL, 0.5 mL, and 0.25 mL increased total leukocytes and leukocyte differential (lymphocytes, neutrophils, monocytes, basophils, eosinophils) with a significant difference (p<0.05) to the Na group CMC 0.5% as a negative control. Therefore, curcuminoid extract had the potential to have an effect as an immunostimulant
Phytochemical Screening And Antidiabetic Test Of Ethanol Extract Of Sapodilla Kecik Leaves (Manilkara kauki (L) Dubard) On Decreasing Blood Glucose Of Diabetic Rats
No full textThe development of traditional medicine needs to be carried out so that Indonesia's natural wealth can be utilized as effectively as possible to improve people's welfare. As with diabetes, some reputable traditional herbal medicines contain antidiabetic properties. Natural antidiabetic drugs derived from compounds isolated from plants can be used as an alternative to traditional medicine for diabetes because they have potential side effects. Diabetes can be treated alternatively by using various substances, especially those containing polyphenols, such as flavonoids. Sapodilla kecik (Manilkara kauki (L.) Dubard) from the Sapotaceae family is a type of plant used in traditional medicine; leaves, roots and bark can be used to treat diarrhoea in children, seeds can be used as a febrifuge, anthelmintic, and as an antileprotic. Secondary metabolites in sapodilla kecik leaves are flavonoids, alkaloids, tannins, triterpenoids and glycosides. This research was carried out by characterizing and screening phytochemicals to determine the content of compounds in Sapodilla kecik (Manilkara kauki (L.) Dubard) and carrying out antidiabetic tests on streptozotocin-nicotinamide-induced diabetic rats. The results showed that sapodilla kecik leaves fulfilled the simplicia characterization requirements. Sapodilla leaves contain secondary metabolites such as alkaloids, flavonoids, tannins, glycosides, saponins and steroids. The ethanol extract of sapodilla kecik leaves at a dose of 500 mg/Kg BW starting from the 4th day of treatment, a dose of 250 mg/Kg BW starting on the 8th day of treatment, and a dose of 125 mg/Kg BW starting on the 12th day was able to reduce the KGD of induced diabetic rats with nicotinamide and streptozotocin
Evaluation Of Drug Storage System In A Pharmacy Of Medan City Based On Pharmaceutical Services Standards
No full textPharmacy is a place where pharmaceutical services are held by pharmacists who are responsible for patients. Pharmaceutical services in pharmacies are related to drugs with the aim of achieving definite results to improve the quality of life of patients. So the management of drugs in pharmacies needs to be done properly and precisely to ensure the availability of sufficient and quality drugs in order to achieve optimal service goals by implementing a storage system that is in accordance with pharmaceutical service standards no.73 of 2016. Therefore the purpose of this research is to evaluate the drug storage system in one of the Medan city pharmacies based on pharmaceutical service standards. This research is descriptive with retrospective data collection. The data obtained were grouped into quantitative data presented in tabular form to see visual comparisons, and qualitative data obtained through observation and interviews with informants. The results showed that in several indicators of drug storage in one of the Medan city pharmacies based on Permenkes No. 73 of 2016 there are still those that have not complied with, namely in the preparation of LASA drugs and writing document numbers on drug stock cards. Meanwhile, the standard drug storage indicators are the columns on the stock card consisting of receipt or dispensing date, receipt or disbursement document number, source of origin of the drug, no. batch/no. Lot, expiry date, receipt and disbursement amount, remaining stock, and officer's initials, as well as suitability for drug storage based on dosage form, alphabetical order, and FEFO and FIFO storage methods. Based on the results of the study it was concluded that the drug storage system carried out in one of the pharmacies in the city of Medan did not meet pharmaceutical service standards based on Permenkes No. 73 of 2016
Isolation And Characterization Of Nitrogen Fixing Fungi From Fruit And Vegetable Waste Compost
No full textNitrogen fixing fungi are fungi capable of fixing free nitrogen into ammonium or nitrate, so that it can be absorbed by plants. Many species of microbes/fungi have the ability to fix nitrogen, but very few are able to excrete nitrogen in the form of ammonia so that their contribution in providing nitrogen for plants is also still low. This study aims to determine the characteristics and type of nitrogen fixing fungi in fruit and vegetable waste compost. The method used in this research was descriptive method. Identification of nitrogen-fixing fungi was carried out macroscopically by looking at the color of the colonies, the shape of the colonies, and the diameter of the fungal colonies, an then identified by molecularly. There were 4 isolates of nitrogen-fixing fungi capable of forming clear zones on Jensen's media with different morphological characteristics and nitrogen-fixing abilities. The largest diameter of the clear zone was shown in isolate A3 of 3.2 cm which is the fungus Aspergillus niger strain SG1
Customer Relationship Management : Literature Review
No full textThe purpose of this article is to provide a more meaningful view of CRM starting from the CRM definitions of several figures along with their orientation and the CRM strategic model framework so that later they can contribute to researchers and companies about CRM implementation and show that by managing customer relationships with both can increase the value of the organization/company. The method used is a literature study derived from previous books and articles that analyze the CRM model. There are 10 models in this article that are presented with comprehensive discussions and reviews that explore customer-centric, technology solutions to improve customer relationships, knowledge management systems, employee involvement in organizational performance
Millennial Farmer Strategies in Horticultural Entrepreneurship
No full textIndonesia has abundant agricultural resources and great potential in agricultural development. The existence of these agricultural resources has not been matched by the low regeneration of millennial farmers. The Ministry of Agriculture of the Republic of Indonesia through the Agriculture and Food Security Service of Gunungkidul Regency projects a Horticulture Village program to be implemented in Karangrejek Village, Kapanewon Wonosari. This program encourages millennial farmers who have their own innovations and strategies in agricultural development, especially in running farming in the horticulture sector. This paper aims to find out the strategies and innovations carried out by millennial farmers in running farming in the horticulture sector. The millennial farmer strategy is carried out when cultivating and marketing horticultural products, especially shallots and chilies. The strategies carried out in the cultivation aspect are: planting with the intercropping method, off season farming, selection of superior seeds, use of biological control agents, and use of high beds. On the marketing aspect of the results: digital media marketing, post-harvest packaging. The characteristics of millennial farmers in dealing with entrepreneurial problems are: never give up, keep trying, innovate and stay afloat in horticultural farming
Uncovering The Relationships Between Strategic Capability, Strategic Flexibility, And Performance
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Strategic flexibility and strategic capability are seen as strategic activities carried out by companies to compete and adapt to the business environment to achieve the expected performance. The objectives of this research are: (1) examine strategic flexibility, strategic capability, and performance by emphasizing their relationships, dimensions and roles of context (2) identify the relationship between strategic flexibility, strategic capability and performance that can be used for future theory development. This research uses bibliometric analysis to map how strategic flexibility, strategic capability and performance intended from several previous journals using VOSviewer. This research concludes that implementing strategic flexibility and strategic capability will result in effective relationships and good firm performance although strategic flexibility is not directly related to the strategic capability. Performance mediates the influence between strategic flexibility and strategic capability. The strategic flexibility is influenced by product innovation, absorptive capacity, and dynamic capability, in the other hand, strategic capability is influenced by network capability. The implication of this research are following researches can add literatures and new theories on the strategic flexibility and strategic capability so that research and discussion on this object can continue to grow.
Keywords: Strategic Flexibility, Strategic Capability, Performanc
The Influence Of Transformational Leadership, Knowledge Sharing, And Academic Integrity On Lecturer Innovativeness
No full textThe purpose of this study, is to test and analyze the factors that influence both partially and simultaneously on the innovativeness of lecturers at 6 First State Polytechnic Colleges in the Ministry of Research and Technology, using a questionnaire that has been tested for validity and reliability against 200 respondents, in a verification way carried out through the method and analysis of structural equation models (Structural Equation Modeling) using Lisrel V.8.80 software. The results of research and hypothesis testing show that transformational leadership, knowledge sharing, and academic integrity affect both partially and simultaneously on the innovativeness of lecturers with a contribution of 73%. Of the three variables, academic integrity has a more dominant influence compared to other variables
Disease Transmission Prevention Management of Washing Hands with Soap for Students: Case Study at the University of Jakarta, Indonesia
No full textThe present study reports the first comprehensive study on management preventing efforts on disease transmission has been carried out by washing hands with soap since hands are the most transmittable disease medium. Hands should always be clean by using washing hands with soap (CTPS) following to the correct steps. Before practicing CTPS, respondents were given counseling about hand washing by carrying out 7 steps of washing hands starting with rubbing the palms, back of the hands, between the fingers, closing the right and left fingertips, rubbing the thumbs, cleaning the fingertips then ending by wiping the wrists, rinse with water and dry. The results of observations in class action research on 47 respondents that are university students in Jakarta Indonesia concluded that most respondents (59.57%) had practiced CTPS correctly. The results of the observations of the CTPS steps or steps can showed that most respondents (86.02%) have carried out these steps, in fact all respondents have carried out step 1 and step 7 correctly. The quality of the implementation of the CTPS steps, which were mostly good, was made possible by the educational factors possessed by the respondents and the information obtained during the counseling before the respondents carried out the CTPS practices. The good quality of the implementation of the CTPS steps was also made possible that most of the respondents around 74.47% were women