International Journal of Science, Technology & Management (IJSTM)
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Immunomodulator Activity Test of Curucuminoid Extract Derived from Turmeric Rhizome (Curcuma domestica Val.) In VCO On Rats Injected with Staphylococcus aureus Against an Increase in The Concentration of Leucocyte and Its Components.
No full textOne of the medicinal Zingiberaceae plants which is regularly used by the society as a traditional remedy is turmeric rhizome. The pharmacological properties of turmeric rhizome include anti-inflammatory, anti-immunodeficiency, anti-viral. Anti-bacterial, anti-fungal, anti-oxidant, anti-carcinogenic, and anti-infectious. This study aimed to identify the immunomodulator activity of curcuminoid extract of turmeric rhizome against the increase of leucocyte and its components, lymphocyte and neutrophil in white Galur Wistar rats that had been injected with Staphylococcus aureus. These test animals were given curcuminoid extract in VCO 100 mg/ml on a dosage of 1 ml, 0,5 ml, 0,25 ml curcuminoid powder 200 mg/kg body weight. Curcuminoid was suspended in Na CMC0,5%, Levamisole 25 mg/kg of body weight suspended in Na CMC 0,5%, VCO 1 ml. For the negative control, merely Na CMC 0,5% was given. The extract was orally given daily for 14 days. On the 4th day, Staphylococcus aureus was injected intra-peritoneally. The rats’ blood was then drawn from the heart and was observed to calculate the volume of the leucocytes, lymphocyte, and neutrophil which was conducted using flow cytometry.The findings suggested that there was a significant difference between the immunomodulatory activity of the curcuminoid extract in VCO at the doses of 1 ml, 0,5 ml, 0,25 ml on the increase in leucocyte, lymphocyte, and neutrophil compared to that of the negative control.Therefore, the findings of this study indicated that the extracts of curcuminoid in VCO could increase the number of leucocytes, lymphocytes, and neutrophils. Thus, the curcuminoid extract of turmeric rhizome in VCO potentially possessed immunomodulatory activity
Mapping The Cultural Landscape of Tumori Village, West Gunungsitoli
No full textTumöri Village is one of nine villages located in West Gunungsitoli District, West Gunungsitoli City, North Sumatra Province. Tumöri Village has various potentials that have not been explored and developed optimally. The natural and cultural resources in the village of Tumöri are hills and forest gardens covering an area of more than 5 hectares, the Mola river flow, beautiful natural scenery, and the presence of 10 traditional Nias houses, along with various other potential cultural arts. For this reason, research is needed to see the potential for natural and cultural tourism, a reference for tourism development in an area like Tourism Villages. Tourism Village includes aspects of developing tourism destinations based on local village wisdom, business development, and tourism industry based on community economy, tourism marketing development, and tourism institutions
Strategy To Increase The Competitiveness Of Umkm In The Tourism And Creative Economy Sector Of Samosir Regency With Go-Digital And Transformational Leadership
No full textMSMEs in the tourism sector play an important role in business development and continue to contribute to economic strength and social development in various countries, one of which is Indonesia, and support each other and contribute to generating foreign exchange for the country. The euphoria of the world community has caused tourism visits to increase, especially after Indonesia officially hosted World Tourism Day or World Tourism Day 2022, which had the impact of becoming increasingly well-known to the tourism sector, especially Samosir Regency. This research took a population of 462 MSMEs in Samosir Regency with a sampling technique, namely cluster random sampling with a sample size of 150 MSMEs in 2 Districts of Samosir Regency. Data sources include secondary data originating from relevant agencies and primary data directly from business actors. Data collection techniques use interview documentation and questionnaires. The research results showed that the influence of Go-digitalization and transformational leadership was positive and significant on competitive strategies for MSME actors in the Tourism and Creative Economy sectors of Samosir Regency. The development of digital technology is increasingly rapid, especially after the pandemic disaster. This also encourages community actors to shop online. It's no wonder that electronic trading platforms are selling well as people's choice for shopping and transactions. MSME digital acceleration is carried out to build competitiveness so that MSMEs can be stronger. Transformational leadership is the process of mobilizing all one's abilities to influence, move, direct other people. Transformational leadership is a process of mobilizing all one's abilities to influence, move and direct other people. The suggestion from this research is government support to encourage and provide assistance to business actors so they are able to compete with other tourism industries. One form of support is for the government to provide space for learning to realize technological literacy through outreach and training to business actors. Then we need to utilize new marketing strategies, actively producing goods that consumers can buy directly for the types of products that are currently on the rise during the pandemic
Phytochemical Screening And Antibacterial Activity Of The Ethanol Extract Of Putri Malu (Mimosa Pudica Linn.) Leaves Combined With Klanceng Honey Against Staphylococcus Aureus Bacteria
No full textMimosa pudica Linn. Leave and honey have been known to have antibacterial activity. The combination of the two is very beneficial as an antibacterial because the hydrogen peroxide content in honey and the flavonoid metabolite compounds in Putri Malu provide a synergistic effect as an antibacterial. The aim of this research was to determine the activity of the ethanol extract of Putri Malu leaves combined with Klanceng honey using the disc diffusion method against Staphylococcus aureus bacteria. The results showed that the resulting extract was thick and blackish-green in colour, with a yield of 25.6%. The results of the phytochemical screening test showed that Putri Malu extract contains alkaloids, flavonoids, glycosides, saponins, and tannins. Characterization results showed that the water content of the extract was 7.28 ± 0.05, water-soluble essence content was 16.03 ± 0.08, ethanol-soluble essence content was 19.65 ± 0.01, total ash content was 4.70 ± 0.00, and essence content acid soluble was 0.17±0.02. Antibacterial testing showed that the best ratio of Putri Malu leaf extract to honey to inhibit Staphylococcus aureus was 9:1, with an inhibitory value of 13.60 ± 0.40 mm. In conclusion, the combination of Putri Malu leaf extract with honey strongly inhibits the growth of Staphylococcus aureus bacteria
Design And Development Of A Portable Alcohol Testing Device For Motorists
No full textThis research aims to design and develop a portable alcohol testing device that can be used to check whether prospective drivers have consumed alcohol before driving. The device is designed with the goal of improving road safety by reducing the risk of accidents caused by intoxicated drivers.In this study, we used the Figaro TGS 2620 alcohol sensor. The device is also equipped with a 16x2 LCD that displays test results directly and accurately. Additionally, we added indicators in the form of LEDs and a buzzer for signaling. The device we designed utilizes an Arduino UNO microcontroller.The test results and evaluations indicate that the portable alcohol testing device can respond to changes in alcohol levels around the sensor. When subjected to a non-alcohol condition, the device shows an average voltage reading of 0.69 V, whereas when subjected to the presence of alcohol, the device exhibits an average voltage reading of 3.97 V
A Systematic Literature Review: A Comparison Of Available Approaches In Chatbot And Dialogue Manager Development
No full textThe present study reviewed a number of articles chosen from a screening and selecting process on the various different methods that can be used in the context of chatbot development and dialogue managers. Since chatbots have seen a significant rise in popularity and have played an important role in helping humans complete daily tasks, this systematic literature review (SLR) aims to act as a guidance for future research. During the process of analyzing and extracting data from the 13 articles chosen, it has been identified that Artificial Neural Network (ANN), Ensemble Learning, Recurrent Neural Network (RNN), and Long-Short Term Memory (LSTM) is among some of the most popular algorithms used for developing a chatbot. Where all of these algorithms are suitable for each unique use case where it offers different advantages when implemented. Other than that, dialogue managers lean more towards the field of Deep Reinforcement Learning (DRL), where Deep Q-Networks (DQN) and its variants such as Double Deep-Q Networks (DDQN) and DDQN with Personalized Experience Replay (DDQN-PER) is commonly used. All these variants have different averages on episodic reward and dialogue length, along with different training time needed which indicates the computational power needed. This SLR aims to identify the methods that can be used and identify the best proven method to be applied in future research
Smart City Development Strategy of Wonogiri Regency
No full textTechnology transformation in the smart city concept begins with the implementation of policy transfer to local governments. Wonogiri Regency is one of the districts that implement smart city policy transfer from the central smart city policy. So it is necessary to analyse regional strategies in implementing smart cities. Regional smart city strategy analysis is an analysis carried out to assess the strengths weaknesses opportunities and threats in order to get a picture of the capacity and capability of the region in implementing smart city development programmes. This research aims to analyse the smart city development strategy of Wonogiri Regency. With the regional strategy analysis, Wonogiri Regency can map the right programme according to the dimensions of smart city. So that the implementation of this smart city can run smoothly in accordance with the goals of the Indonesian smart city movement. This study took a locus in Wonogiri Regency, which has a sufficient SPBE index and was chosen to be one of the implementers of the Indonesian smart city movement. Researchers used qualitative methods to analyse the strengths, weaknesses, opportunities and threats of Wonogiri Regency to develop appropriate strategies for these conditions. Researchers found that the smart city strategy is combined with other strategies to solve the problems of the Wonogiri community. The smart city action plan is formed from action plans for smart governance, smart environment, smart society; smart living; smart economy, and smart branding. The action plan must adjust to the strategy formed. The focus of the Action Plan from Wonogiri Regency is to provide integrated services ranging from data to applications.
 
Implementation of Naïve Bayes Algorithm in Sentiment Analysis of Twitter Social Media Users Regarding Their Interest to Pay the Tax
No full textSince 2008, tax revenue has failed to reach the target set in the State Budget each year. Until 2021, tax revenue managed to reach the target that had been targeted in the 2021 state budget. In the midst of improving tax revenue, towards the end of February 2023, a case involving the son of a Directorate General of Taxes (DGT) that made the father called by the Corruption Eradication Commission (CEC) to be asked for an explanation of his assets. After the case, there were many calls in the community to stop paying taxes, which was assessed by Tauhid Ahmad as Executive Director of Indef as a form of decreased trust in tax collecting institutions. This can affect the amount of revenue from taxes because trust in the government is one of the factors that tend to affect public compliance in paying taxes. Which can affect the amount of revenue from taxes because trust in the government is one of the factors that tend to affect public compliance in paying taxes. One of the crowded calls is the pros and cons of the tax boycott movement on Twitter. With the pros and cWith the pros and cons of the movement that can affect tax revenues on Twitter social media, an assessment based on sentiment analysis is needed which is divided into positive, neutral, or negative categories. Sentiment analysis in this research is carried out using three variations of Naïve Bayes assisted by the TF-IDF word weighting model, namely Gaussian Naïve Bayes, Multinomial Naïve Bayes, and Bernoulli Naïve Bayes. Then Confussion Matrix is used to evaluate the model by obtaining the accuracy, precission, recall, and f1-score values and the use of Synthetic Minority Oversampling Technique (SMOTE) to handle unbalanced data. The results of this study on unbalanced data, the implementation of Bernoulli Naïve Bayes using the SMOTE technique on a dataset comparison of 80:20 resulted in better performance than the variations of Gaussian and Multinomial Naïve Bayes with accuracy results of 91.03%, precision, 71.11%, recall 71.43%, and f1-score of 71.18%
The Effect of Dendrophthoe pentandra (L.) Miq Ethanol Extract on Malondialdehyde (MDA) in Hyperglycemic Rats
Get PDFDendrophthoe pentandra (L.) Miq is a parasitic plant with medicinal potential found in 3000 other plant species. The duku parasite is usually considered a parasite on the duku plant and is often discarded because it is thought to interfere with the growth of the duku plant. The purpose of this study was to see the effect of the duku parasite leaf extract on the reduction of malondialdehyde (MDA) in hyperglycemic rats. MDA levels were measured by thiobarbituric acid-reactive substance (TBARS) assay with doses of duku mistletoe leaf ethanol extract of 400, 200, and 100 mg/kg BW. MDA levels were analysed using rat blood plasma, which was measured using a spectrophotometer at a wavelength of 532 nm. Oral administration of EEDBD 400, 200, and 100 mg/kg BW reduced MDA levels in hyperglycemic rats. However, only EEDBD 400 mg/kg BW showed a significant difference between the negative control (CMC-Na), but with glibenclamide and the normal groups, there was no significant difference.
 
Prototyping Of Precission Farming Hydroponic Garden Using Arduino Using Design Thinking Method At Puriponic Greenhouse Depok
No full textThis research discusses precision farming in hydroponic greenhouse using design thinking methods and sensors to ensure process control and monitoring in hydroponic greenhouse. The place of research was conducted at Puriponic Greenhouse Depok. During the Covid-19 pandemic there were social problems with many employee quarantines. Quaranitine occurs, activities are carried out at home, and there also many effect of unemployment. This will cause food problems for the community to be disrupted. This hydroponic system designs a system using an Arduino device with 6 sensors to control and monitoring hydroponic greenhouse. The methodology used is Design Thinking, the research time is 2022. The systems uses 6 sensors and 6 actuators. The result of this study are the design of hydroponic system prototype along with an actuator to guarantee hydroponic control and monitoring. The novelty of this system is the actuator of each sensor in guaranteeing control and monitoring of the greenhouse