Journal of Basic and Applied Research in Biomedicine
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    216 research outputs found

    Antimicrobial and Immunomodulatory activities of Moringa peregrine- MINIREVIEW

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    Moringa peregrina is considered as miracle tree. Extracts as well as some isolated compounds of Moringa peregrine show valuable biological activities, such as antimicrobial, antiviral, anticancer, antioxidant, immunomodulatory. On the other hand, Moringa peregrina is used traditionally as home cleaning agent, fertilizer, foliar nutrient, green fertilizer, gum, honey- and sugar cane juice-clarifier, biopesticide. In this review, the natural distribution and the general features for Moringa peregrina were discussed and the antimicrobial and immunomodulatory activities of Moringa peregrine extract were described. This review might guide researchers to undertake further investigation regarding this species and to use it as a source of active compounds

    Geophysical Mapping of the Proposed Osun State Housing Estate, Olupona for Subsurface Competence and Groundwater Potential

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    Structural failure and water scarcity are one of the infrastructural challenges man faces today. The importance of foundation studies before erecting civil engineering structures such as buildings and highway cannot be overemphasized. Regardless of structure put on the surface of the earth, if the foundation or the subsurface structure is weak, such structure will eventually collapse. Groundwater exploration is gaining more importance in Nigeria owning to ever increasing demand for water supplies, as rain water and surface water are either scarce to get or got polluted by human activities. The study is therefore aimed at characterizing the subsurface for engineering competence and groundwater potential in Olupona Housing Estate, Ayedire Local Government Area, Osun State, Nigeria. An integrated geophysical mapping involving the Electromagnetic (VLF-em) and Vertical Electrical Sounding (VES) were carried out around the proposed housing estate, Olupona, Southwestern Nigeria in order to evaluate subsurface competency for engineering activities and the groundwater potential beneath the study area. Seven (7) traverses were each established for VLF-em survey in S-N and E-W orientation while Sixteen (16) VES stations were deployed along five (5) traverses in order to cover the entire study area. The data obtained were analyzed and processed qualitatively and quantitatively. The VLF-em revealed several geological features which ranged from -18.0 to 12.0 Sm-1. Positive conductivity zones and negative conductivity zones were mapped in the study area. Some of the positive conductivities mapped showed that the conductive anomalies extended from surface to the depth of 40.0 m. VES analysis revealed three-to-four lithologic sequences which include topsoil, lateritic layer (not present in all), weathered layer, and fractured or fresh bedrock. H-type, HA-type and KH-type were the curve types obtained from VES data with the overburden thickness ranging from 8.0 to 51.66 m. It is concluded that the study area is underlain with thick overburden, thus making the study area unsuitable for construction of high-rise buildings. It is also affirmed that groundwater exploration is sparingly favoured in the study area

    Prevalence of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency among Neonates with Jaundice in a Tertiary Hospitalin Nigeria

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    G6PD deficiency is known to be associated with neonatal jaundice, kernicterus and even death. G6PD is the first enzyme of the pentose phosphate pathway and catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolactone, with the concomitant reduction of nicotinamide adenine dinucleotide phosphate (NADP) to its reduced form (NADPH). Three hundred and twenty five neonatal blood samples were collected for the study between the ages of 1–10days of both sexes. About 4ml of blood sample was collected from newborn baby with jaundice, 2ml of blood sample was dispensed into di-potassium ethylenediaminetetracetic acid (K2EDTA) bottles for packed cell volume and haemoglobin estimation using haematology analyzer (sysmex model KX-21N) also K2EDTA blood sample was used for G6PD status determination, remaining 2ml of blood sample was dispensed into heparin bottles for bilirubin estimation. Out of 325 newborn babies with neonatal jaundice, 96(29.5%) were G6PD deficient; 57 were male and 39 were female. Mean± SD of total bilirubin (B1) andconjugated bilirubin(B2) were significantly (P<0.05) higher in G6PD- deficient participants compared with G6PD normal. Neonates should be screened for G6PD deficiency when family history, ethnic or geographic origin on the timing of the appearance of neonatal jaundice suggests the possibility of G6PD deficiency.

    Scientific and Applied Research of ICPS for Agriculture: Mini Review

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    The scientific and applied achievements of Institute of the Chemistry of Plant Substances (ICPS) on the development of products for agriculture for the last years are summarized. Also included different research areas, working to find new promising drugs based on natural, heterocyclic compounds and their synthetic analogues. In this mini review many preparations: plant growth regulators, fungicides, herbicides, which are created in ICPS and recommended for application in agriculture, have been discussed

    Phytochemical Screening and Pharmacological Activity of Seed Extract and Seed Oil of Lagenaria siceraria.

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    The present study includes detailed aspects of seeds of Lagenaria siceraria (Mol.) Standley used as medicinal plant. The Lagenaria seeds contain steroidal moieties like avenasterol, codisterol, elesterol, isofucasterol, stigmasterol and Legenin, a ribosome inactivating protein(RIP) isolated from seed shows various pharmacological activity. Antioxidants consist a group of vitamins, minerals and enzymes that have health enhancing effects. Antioxidants terminate the chain reactions by removing free radical intermediates before they do harm to our bodies. Antibacterial agents are inhibitory chemicals employed to kill micro-organisms or prevent their growth.Antianxiety agent a pyschotropic medication involves functional category of drugs useful in the treatment of anxiety and able to reduce anxiety at dosage that not cause excessive sedation.The elevated plus maze is a widely used behavioral assay for rodents and it has been validated to assess the anti-anxiety effects of pharmacological agents.An increase in open arm activity reflects anti-anxiety behavior

    Effect of 2.4 GHz WiFi Frequency Electromagnetic Wave Radiation on Green Bean’s Growth

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    In this research, access points are placed near the green bean’s seed to identify the effect of 2.4 GHz electromagnetic waves to green bean’s growth. There are 3 groups of green bean’s seed, one is positioned near one access point, another is positioned near two access points, and the last is positioned near 3 access points. For the control treatment, another sample group is placed in area without WiFi access, with 30cm distance and 6 x 24 hours times elapsed. The result shows that samples with 63 mV/m electric field strength that comes from 3 WiFi access points could grow till 8.6 cm, the samples with two access points with its electric field strength 63V/m could grow until 8.8 cm, and samples with one Wi-Fi access point with electric field strength of 0.792 mV/m could grow until 9 cm. As for the controlling samples, it could grow until 9.5 cm. From the result, we can conclude that samples will grow slower when they are affected by the electromagnetic wave radiation. We assumed that the radiation of 2.4 GHz electromagnetic waves disturb the performance of the green bean’s growth

    Knowledge and Practices among Nurses Regarding Hygiene in the Care of Comatose Patient in Surgical and Medical Ward in a Government Hospital in Jordan

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    Background: Hygiene refers to conditions and practices that helps maintain health and prevent the spread of diseases. Whereas in popular culture and parlance it can often mean mere “cleanliness,” hygiene in its fullest and original meaning goes much beyond that to include all circumstances and practices, lifestyle issues, premises and commodities that engender a safe and healthy environment. The aim of this study is to assess the knowledge and practice of nurses regarding hygiene in the care of comatose patient in a Government Hospital in Jordan. Materials and methods: The study was conducted during the period of 1 st June 2016 to 1st December 2016. The design of this study is Descriptive cross – sectional hospital base analysis by manual analysis method. This is a type of study in which a condition and potentially related factors are being measured at a specific point in time for a defined population (NEDARC, 2016). Results: The study respondents were fifty (50) nurses, among these respondents, twenty six (26) were males and twenty four (24) were females which was ethically informed to participate in this study. The study showed that knowledge of nurses about hygiene in the care of comatose patient were 45% good, 40.1% poor knowledge and 14.9% moderate knowledge. Conclusion: The present study concluded that study sample has a moderate to good knowledge. Based on the study findings it is recommended that the nurses needs to attend courses and trainings about hygiene of comatose patient to improve their practice

    Comparative Study of the Regulatory Framework on Microfinance

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    Microfinance is a source of financial services for people who are unable to gain access to traditional banking and financial services. Microfinance is based on two ways of being able to deliver financial services to people. Proponents of microfinance believe that this could be the way to help poor people out of poverty. This paper will analyze this relationship and look at the impact of both regulations and supporting institutions on various indicators of MFI performance for a sample of 79 countries. This will be done in order to determine if MFIs in countries with regulations that should be conducive to microcredit, result in a statistically significant increase in cost per borrower. These types of insights are important as the results will highlight a framework of regulation that a country trying to spur economic growth (through microfinance) could implement to create the highest likelihood of success for existing and upstart MFIs. The countries which are sampled are stratified by income, using a classification system created by the World Bank based on gross national income

    Evaluation of Celest Top® 312.5 FS (fludioxonil 25g/L; difenoconazole 25g/L; thiamethoxam 262g/L) to control insect pests and seedling diseases on wheat at River Nile and Kassala States, Sudan

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    The experiments were conducted at Hudiaba research station farm (River Nile State) and New halfa Research Station (Kassala State) for two consecutive seasons 2014/015 and 2015/016, to evaluate the effectiveness of Celest Top 312.5 FS (flowable solution) as seed dressing to control insect pests and seedling diseases of wheat. Celest Top 312.5 FS was used at the rates of 1.25ml/kg seed, 1ml/kg seed and 0.75 ml/kg seed with its respective (standard) check 1.5g/kg Raxil2% WS (tebuconazole) + 0.5g/kg Gaucho70% WS (imiddacloprid) and untreated control. In contrast, Celest Top 312.5 FS at the rates of 1ml/kg and 1.25ml/kg seed significantly (P≤ 0.01) reduced green bug and termite infestation and seedling diseases of wheat and increased wheat grain yield compared to the untreated and standard. In vitro evaluation of Celest Top 312.5 FS against Pythium spp. revealed that the pesticide containing fungicidal components significantly inhibited the mycelia growth of test pathogen. Results of residue analysis showed that no detectable levels of Celest Top 312.5 FS were found in all samples of wheat collected at harvest

    Impact of Stage of Change and Gender on Motivation to Participate in Recreational Activity and Perceptions of Health.

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    Regular recreational activity has numerous mental, physical, and social health benefits. To examine motivations to engage in recreational activity and perceptions of health by gender and Stage of Change (SOC), an online survey was developed and promoted in the Southeastern region of United States in Spring 2015. Using General Linear Model Analysis of Variance (GLM), motivation to participate in recreational activity and perceptions of health (dependent variables) were examined by the independent variables of gender and SOC (covariate). Participants included 735 adults (58.23% female). Females were more likely than males to use recreational activity “to improve physical health and fitness” (Female: M=1.31, Male: 1.42, p < .05) and “to insure mental health and well-being” (Female: M = 1.42, Male: M = 1.61, p < .001).    Females perceived better health than males (Female: M = 2.11, Male: M = 2.20, p <, .05).  These same items were also significant by SOC with responses decreasing (more likely to agree) by 15.7% (p< .001), 13.15% (p < .0001) and 26.26% (p < .05) for each unit increase in SOC. Needs assessments conducted in this manner may increase participation by allowing for targeted messages to be created for various population groups

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