Jurnal Farmasi Fakultas Kedokteran Universitas Mataram
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Penetapan kadar vitamin C pada daun kelor (Moringa oleifera L.) dan bayam hijau (Amaranthus gangeticus L.) dengan metode spektrofotometri UV-Vis
Full text linkVitamin C is a compound that cannot be formed by the body itself. Vitamin C is needed to regulate metabolic processes and normal body functions. Lack of vitamin C can cause a decrease in the immune system. During a pandemic, vitamin C is needed to improve the immune system to prevent and fight disease infections. The pandemic has caused an increase in the need and price of vitamin C supplements in the market. Fulfilling the body’s vitamin C needs can use alternatives such as Moringa leaves and green spinach. This study aims to determine the levels of vitamin C in Moringa leaves and green spinach with variations in temperature and concentration. Analysis of vitamin C was carried out using UV-Vis spectrophotometry at a wavelength of 516 nm. The results of the determination of vitamin C levels in Moringa leaves and green spinach obtained the highest levels of 24,9948% and 19,0205%, and the lowest levels of 2,2456% and 1,8710%. The results of the ANOVA test showed that there was a significant difference in the levels of vitamin C obtained at the given temperature and concentration variations
Sosialisasi rintisan pengembangan desa wisata kebugaran kelurahan Canden kabupaten Bantul D.I Yogyakarta
Full text linkCanden, a village in the Bantul Regency, is one of the tourism settlements with the potential to develop. The village of Canden comprises 15 hamlets, one of which is Kiringan, recognized as a hub for conventional herbal medicine. This hamlet is home to at least 110 herbal medicine vendors. This community service project aimed to make it easier for the town of Canden to thrive as a tourism destination, starting with the potential of herbal medicine as the foundation of wellness travel. This community service approach was participatory rural appraissal using focus group discussion with community, tourism management, head of the tourism office, public health center, university, and so on.  This community service was carried out smoothly and the results were obtained in the form of community mapping and identification of needs in the development of fitness tourism villages
Edukasi penggunaan sediaan tabir surya sebagai upaya pencegah penuaan dini dan kanker kulit di SMAIT Anak Sholeh Mataram
Full text linkProlonged sun exposures can have negative impacts to skin such as premature aging and skin cancer. These impacts can be minimized by using sunscreen. Unfortunately, majority of Lombok islanders, especially students, still not aware on sunscreen benefits and applications. Therefore, community service is conducted to educate on the danger of prolonged sun exposures on skin and on how to apply sunscreen to prevent skin aging and skin cancer. The method consists of preparation stage, pre-test, education, and evaluation. The community service on SMAIT Anak Sholeh Mataram is considered to be positive by the involved party. This activity has been an early education for the students about how to prevent premature aging and skin cancer. Furthermore, the test result shows there is a positive increase on the training participants’ knowledge
Penggunaan obat off-label pada pasien anak di salah satu rumah sakit daerah Provinsi Nusa Tenggara Barat tahun 2017
Full text linkDue to insufficient pharmacokinetic-pharmacodynamic data, off-label medication usage in children is commonly observed. It might result in Drug Related Problems (DRPs) that could lead to morbidity in youngsters. In one of West Nusa Tenggara Province's public hospitals, this study sought to gain a general understanding of pediatric patients between the ages of 4 and 14 who were using off-label medications. Retrospective descriptive methodology is used in this investigation. For each of the following categories: age, indication, contraindication, dosage, and method of administration, the percentage of off-label drug use was calculatedbased on medical records and literature reviews. Out of 302 medications prescribed to outpatients, 14 (4.63%) and 5 (1.65%) were off-label for the patient's age, and indication categories were determined.Regarding inpatients, out of 369 medicines, the categories for age, indication, and dose, respectively, indicated 7.85% (29), 1.08% (4), and 2.43% (9) off-labels. Both pediatric inpatient and outpatient patients were found to be using drugs off-label. To ascertain the impact of off-label pharmacological advantages on the efficacy of drug therapy, more research is required
Edukasi terkait langkah pengembangan formula dan registrasi kosmetik melalui webinar
Full text linkIndonesia is a potential market for cosmetics. Students and lecturers at Departments of Pharmacy developed various cosmetic formulas, but limited to research or publications only. Lack of knowledge about the stages of developing good cosmetic formulas, good manufacturing cosmetics, and the steps in registration of cosmetic preparations is the main cause in developing cosmetic products. The method used in this community service is online conference. The participants were given a pretest and posttest to determine their level of understanding about cosmetics formula development and registration. About 190 participants attended the conference. Assessment by pretest and posttest obtained an average result of 50.22 ± 13.36 and 70.05 ± 18.97 respectively. The results show that there is a significant difference between pretest and posttest. The conference was considered good by the participants with an average score of 3.68 of 4. This conference provided increased knowledge to participants regarding the development of cosmetic formulas and the steps in cosmetic registration
Aktivitas antioksidan dan uji sitotoksik infusa daun jarak pagar (Jatropha curcas)
Full text linkAntioxidants are crucial in preventing cell damage caused by oxidation from oxidants. The use of antioxidants from natural products such as Jatropha curcas leaves can counteract free radicals due to the presence of secondary metabolites. The main aims of the study were to determine the antioxidant and cytotoxic activity of the infusion of J. curcas leaves. The sample was extracted using the infusion method. A qualitative phytochemical screening was carried out using the test tube method, antioxidant assay using the DPPH method and cytotoxic using the BSLT method. The results showed that the infuse of J. curcas leaves contained secondary metabolites such as polyphenols and tannins, alkaloids, flavonoids, and saponins. In the antioxidant activity test, infuse of J. curcas leaves and vitamin C (control) the IC50 was 58.90±2.34 ppm and 8.78±0.21 ppm respectively. The infused cytotoxic test contained an active toxic compound in shrimp larvae with an LC50 of 200.28 ppm (LC50 ≤ 1000 ppm). Based on the results of the study, infuse of J. curcas leaves showed potential as an antioxidant and anticancer agent with a strong classification
Pelatihan pembuatan sabun cair cuci tangan untuk mencegah penyakit covid-19 dan hepatitis pada sekolah dasar di Kabupaten Parigi Moutong
Full text linkCommunity service carried out by providing training in making liquid hand washing soap in elementary schools is the first step that can be taken to prevent Covid-19 and Hepatitis in elementary school children. The community service activities are carried out using various methods, namely by identifying or surveying existing partners, providing counseling and providing the practice of making liquid hand washing soap. The number of participants in community service was 30 participants consisting of students and teachers. The results of the community service activities, the participants welcomed enthusiastically and made an active contribution in participating in the training activities with the hope that the participants could carry out the stages of making liquid hand washing soap independently from the training that had been given
Perbandingan biaya terapi hemodialisis dengan peritoneal dialisis di Asia: Narrative review
Full text linkThe high prevalence of Chronic Kidney Disease (CKD) patients increases the demand for dialysis therapy. Studies comparing dialysis modality therapies undergone by CKD patients in the Asian region are still limited. The research objective is to compare the costs of Hemodialysis (HD) and Peritoneal Dialysis (PD) therapies in Asian countries. The review of 4 Asian regions indicates that patients undergoing HD therapy have a higher financial burden than PD therapy. The main costs affecting the high expenses of HD therapy come from the remuneration of healthcare professionals specialized in assisting patients, including doctors, nurses, and technicians. Productivity loss and transportation costs also contribute to HD therapy's higher costs than PD therapy. However, in the Western Asian region, PD therapy costs more than Hemodialysis therapy. PD therapy costs more due to additional direct medical expenses such as filters, bicarbonate cartridges, tubes, acid dialysate, and pyrogen filters
Peranan ACE-Inhibitor pada penyakit jantung bawaan
Full text linkAngiotensin-converting enzyme inhibitors have been shown to have the broadest impact of any drug in cardiovascular medicine. Dual role of ACE inhibitors, both preventing and treating cardiovascular disease. ACE inhibitors have an indirect effect on primary prevention by lessening hypertension and decreasing left ventricular hypertrophy, especially in patients with cardiac failure. In children, the causes of cardiac failure are significantly different and many cases are due to congenital malformations, such as left-to-right- shunts. In these patients, the function of both the right and the left ventricles will be affected and these children suffer from high-output cardiac failure. Therefore, in carefully selected patients with congenital heart disease, the response to systemic afterload reduction with ACE inhibitors appears favorable. Nevertheless, a more comprehensive controlled trial to assess the hemodynamic and functional effects of ACE inhibitors in such patients should be undertaken
Formulasi dan uji aktivitas sediaan lotion tabir surya ekstrak etanol 96% bekatul beras merah (Oryza nivara)
Full text linkBrown Rice Bran (Oryza nivara) contains phenolic compounds, flavonoids, tannins, steroids, or terpenoids that can function as an antioxidant activity that can protect the skin from the adverse effects of UV rays of the sun. Extraction was carried out by maceration method using 96% ethanol as solvent. The viscous extract obtained was then subjected to phytochemical screening and SPF test and made into three different concentrations, 5%, 10%, and 15%, which would then be formulated into a sunscreen lotion dosage form. The resulting preparations evaluated the physical quality of lotion preparations in the form of organoleptic tests, homogeneity tests, pH tests, dispersibility tests, and SPF tests of preparations. The results of the SPF test extract with concentrations of 5%, 10%, and 15% showed that the protection produced was in the ultra-category with SPF values respectively 31.1, 40.1, and 45.1. The results of the physical evaluation of the preparation of sunscreen lotion with brown rice bran extract showed that the lotion produced was not homogeneous, and the results of the pH test and dispersion test still met the requirements. Testing the SPF value of lotion preparations showed that the protection produced by each formula was in the maximum to ultra-category with SPF values of 11.7, 14.1, and 16.4, respectively