GreenPrints Institutional repository of De La Salle Medical and Health Sciences Institut
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Synergistic antioxidant activity of Psidium guajava (guava) and Musa x paradisiaca (banana) ethanolic leaf extracts
No full textPerception of senior high school students on comprehensive sexuality education in De La Salle Medical and Health Sciences Institute
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Knowledge and attitude of staff nurses towards palliative care in selected hospitals in Dasmariñas Cavite
No full textArtwork 059: Memories of Kalinga
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Artwork 043: Why We Celebrate
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Artwork 078: The Golden Cage
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Effectiveness of using the pomodoro technique to improve the academic performance among third-year students of medical laboratory science at the De La Salle Medical and Health Sciences Institute S.Y. 2023-2024
No full textAnti-angiogenic property of Kutsarita leaf (Alternanthera ficoidea) extract determined through Chorioallantoic membrane assay
No full textAlternanthera ficoidea, commonly known as Kutsarita, is a tropical ornamental plant with documented medicinal properties, including antioxidant and anti-inflammatory effects. This study investigates the anti-angiogenic potential of ethanolic A. ficoidea leaf extract using the Chorioallantoic Membrane (CAM) assay. Phytochemical screening confirmed the presence of bioactive compounds such as flavonoids, alkaloids, diterpenes, tannins, phenols, and saponins— compounds linked to anti-angiogenic mechanisms. Varying concentrations of the extract (2,500– 10,000 ppm) were injected into fertilized duck eggs, with Paclitaxel (6,000 ppm) serving as the positive control. Using IKOSA Prisma software and ANOVA for analysis, significant reductions in blood vessel formation were observed at 7,500 ppm and 10,000 ppm concentrations, comparable to Paclitaxel (p \u3c 0.05). These results suggest that A. ficoidea possesses concentration-dependent anti- angiogenic activity, likely due to the synergistic effects of its phytochemicals. This study supports the potential of A. ficoidea as a natural source for anti-angiogenic agents and encourages further investigation into its mechanisms and possible integration in cancer therapy development
