International Journal of Medical Research & Review (IJMRR)
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NERVE SHEATH MYXOMA IN AN UNCHARTED TERRITORY
Full text linkDermal nerve sheath myxoma is a rare benign tumor of perineural schwann cells of peripheral nerves1. It commonly affects limbs of younger adults with peak incidence in thirties2 and has a high recurrence rate if not fully excised. This is a case of an elderly female who presented with a swelling in the right nasal cavity. Excision biopsy of the mass was done and histopathology showed features of nerve sheath myxoma
Individualized Homoeopathic Medicines Alleviated the Recurrent Epistaxis in Identical Twins with Severe von Willebrand Disease and Haemophilia A: A Duo Case Report.: Homoeopathy in vWD
Full text linkBackground: von Willebrand Disease (vWD) is an inherited genetic bleeding disorder that prevents the blood from clotting. Prevalence of vWD is estimated to be approximately 1% of the population (or 10,000 cases per million population). The vWF binds and stabilizes blood clotting factor (FVIII) in circulation and therefore it helps in clot formation.
Case Profiles: This duo case report is the classical example of association of vWD with haemophilia A in identical twins, where both the patients shared the same disease pattern and manifestations like recurrent epistaxis & ecchymotic patches. But when it came to homoeopathic prescription both of them were prescribed 2 different constitutional medicines on the basis of their behavior, constitution, etc.
Result & Discussion: ISTH-BAT (International Society on Thrombosis and Haemostasis-Bleeding Assessment Tool) scale was used to measure the frequency of epistaxis and bruises which reduced from 6 to 1 in the elder twin and from 7 to 4 in the younger one. Modified Naranjo Criteria in Homoeopathy was used to assess the homoeopathic result with the score of 10 for the elder twin and 8 for the younger twin. This Duo Case Report signifies the role of two different Individualized Homoeopathic Medicines in the identical twins though sharing the similar disease pattern.
Conclusion: Homoeopathic medicines prescribed on the basis of individualization alleviated the genetic disease symptoms and improved the quality of life of the patients’ and the family members
A Smoke free pregnancy: Pure bliss and gift of health to you & your baby : smoke free pregnancy: Pure bliss and gift of health
No full textThis article emphasizes the importance it is to refrain from smoking during pregnancy for the sake of the mother\u27s and the unborn child\u27s health and wellbeing. Significant concerns associated with smoking during pregnancy include low birth weight, preterm delivery, and developmental issues. Pregnant women can foster an environment of wellness that promotes ideal foetal growth and lowers the risk of long-term health problems by deciding not to use smoking. According to the article, quitting smoking during pregnancy not only brings about sheer joy but also serves as a crucial gift of health, providing a solid basis for a healthy future for both the mother and the unborn child. For best outcomes during pregnancy, empower and encourage women to make the commitment to live a smoke-free lifestyle
A Study to Assess The Knowledge Regarding Silicosis among the Workers of Stone Cutting and Art Industrial Area Sikandra, Dausa, Rajasthan, With a View to Develop an Information Booklet
No full textIntroduction: Silicosis is an incurable occupational lung disease resulting from prolonged inhalation of crystalline silica dust, primarily affecting workers in the stone cutting and stone art industries.Despite its severe health implications, knowledge regarding silicosis among workers remains limited, leading to increased morbidity and mortality.
Materials and Methods: A descriptive design within a quantitative research approach was employed for this study Data was collected using a self-structured knowledge interview schedule to evaluate workers knowledge about Silicosis A convenient sampling method was employed to select 100 workers from the Stone Cutting and Art Industrial area of Sikandra, Dausa, Rajasthan. The structured knowledge interview schedule gathered both Background details and knowledge-related questions about Silicosis. The collected data was organized, analyzed, and interpreted utilizing descriptive statistics.
Results: The results revealed that 62% of participants had average knowledge, 35% had good knowledge, and 3% had poor knowledge regarding Silicosis. The mean score was 18.28, with a standard deviation of 3.9. , The overall average knowledge score stood at (score 11 to 20) 33.33% to 66.66% . A statistically significant relationship was identified between knowledge and the workers education and monthly income (p < 0.05), while no association was observed with other demographic factors such as age, work experience, and sources of information
Conclusion: The study highlights the need for enhanced education and awareness programs to improve workers\u27 knowledge of silicosis. Based on the findings, an information booklet was developed to promote health education and preventive measures. The study emphasizes the importance of workplace interventions, regular health check-ups, and policy implementation to mitigate the risks of silicosis
Rapid Risk Stratification Score as A Predictor Of Adverse Outcome In Empyema - A Prospective Cohort Study
Full text linkBackground: Empyema, the accumulation of pus in the pleural space, remains a serious complication of pneumonia. The RAPID score (Renal function, Age, Purulence, Infection source, Dietary factors) predicts outcomes, but its broader clinical utility is not well established. Objectives: To assess the RAPID score as a predictor of adverse outcomes in empyema and evaluate associated clinical factors in a tertiary care setting.
Methodology: A prospective cohort study was conducted in the Department of Pulmonary Medicine, Government Medical College, Thiruvananthapuram, over 12 months. Sixty patients with empyema were enrolled. Demographic, clinical, biochemical, microbiological, and radiological data were collected. RAPID scoring was done at presentation, and patients were followed up at 1 and 3 months for readmission, intervention, mortality, and clinical resolution.
Results: Of 60 patients, 81.7% were male, mostly aged 50–70 years. Diabetes (56.7%) and COPD (20%) were common comorbidities; smoking (63.3%) and alcohol use (65%) were major risk factors. Non-purulent effusion occurred in 25%, while 50% of cultures were sterile. Pseudomonas (16.7%), Klebsiella (13.3%), and Staphylococcus aureus (13.3%) were frequent isolates. CT showed split pleura sign in 88.3% and parenchymal involvement in 61.7%. Ninety-day mortality was 26.7%, significantly higher in patients with high RAPID scores (75%, p=0.0001), hypoalbuminemia (93.7%, p=0.0001), elevated urea (68.7%, p=0.0002), and hospital-acquired infection (57.1%, p=0.04). Readmission (25%) was mainly due to COPD exacerbation or recurrence.
Conclusion: RAPID score with serum biomarkers reliably predicts outcomes. Advanced age, elevated urea, hypoalbuminemia, hospital-acquired infection, and non-purulent effusion significantly increase mortality risk
The Effect of Kinesio Taping in The Treatment and Prevention of Shoulder Injuries and Pain in Badminton Players: A Narrative Review: Effect of Kinesio Taping in The Treatment and Prevention of Shoulder Injuries and Pain in Badminton Players: A Narrative Review
No full textBackground: Badminton is a high-intensity overhead sport that predisposes athletes to various shoulder injuries, including rotator cuff tendinopathy, impingement syndromes, and tendonitis. These injuries often result from repetitive motions such as smashes and clears. Kinesiotaping (KT) has emerged as a popular adjunct therapy in sports rehabilitation, believed to provide pain relief, enhance proprioception, support injured tissues, and prevent injuries without limiting range of motion.
Objective: This narrative review explores the effects of Kinesio taping on shoulder pain, injuries, and their prevention in badminton players, summarizing evidence from existing literature.
Methodology: A comprehensive search was conducted across Google Scholar, PubMed, EBSCO, Medline, and ScienceDirect for peer-reviewed articles published between 2007 and 2024.
Result: The literature indicates that KT may offer short-term benefits in improving shoulder range of motion and reducing pain, particularly in conditions like rotator cuff injuries, impingement, and bicipital tendinitis. Preventive benefits were also observed, with some studies reporting reduced injury incidence among badminton players using KT regularly. However, the long-term effectiveness of KT remains inconsistent, with several studies finding no significant improvements in pain or function compared to placebo or conventional treatments. KT appears most effective when combined with physiotherapeutic interventions such as mobilization and strengthening exercises.
Conclusion: KT demonstrates potential as a supportive modality in managing and preventing shoulder injuries in badminton players, especially for short-term relief and functional improvement. However, due to variability in application techniques and methodological limitations in existing studies, it should not be considered a standalone treatment.
Keywords: Kinesiotaping, Shoulder Injuries, Badminton Players, Pain Management, Sports Rehabilitation, Rotator Cuff, Proprioceptio
Ovarian Cancer: A Comprehensive Review: Ovarian Cancer
No full textOvarian cancer is the most fatal gynecologic malignancy, primarily due to nonspecific symptoms that lead to late-stage diagnosis. This review summarizes its epidemiology, key risk factors, pathophysiology, clinical features, diagnostic approaches, staging, and treatment. Global incidence continues to rise, with age, BRCA1/2 and MMR gene mutations, endometriosis, infertility, and lifestyle factors contributing significantly to risk. High-grade serous carcinoma remains the most common and aggressive subtype, often originating from the fallopian tube epithelium. Diagnosis relies on imaging, tumor markers such as CA-125 and HE4, and histopathological confirmation. Optimal debulking surgery followed by platinum-based chemotherapy remains the standard of care, while PARP inhibitors, bevacizumab, and hormonal therapy offer additional benefit. Emerging innovations—including antibody-drug conjugates, gene therapy, immunotherapy combinations, and liquid biopsies—are advancing personalized treatment. Despite progress, the absence of effective screening highlights the need for improved early detection strategies and multidisciplinary management to enhance survival outcomes
PROPORTION OF OBSTRUCTIVE AIRWAY DISEASE AMONG POST PULMONARY TUBERCULOSIS SUBJECTS IN A TERTIARY CARE SETTING
Full text linkBackground: Pulmonary tuberculosis can affect lung function and the pulmonary function test of post-patients shows airway obstruction which is not reversible. This group of patients is in the category of post-TB obstruction syndrome with symptoms and signs similar to Chronic Obstructive Pulmonary Disease (COPD). The objectives of our study are: To determine the factors causing the development of obstructive airway disease in post-tuberculous individuals & To assess the severity of obstruction based on GOLD criteria.
Materials and Methods: The study was conducted in the Department of Pulmonary Medicine, Government Medical College Hospital, Thiruvananthapuram. This was a cross-sectional study that included patients with a history of pulmonary tuberculosis, (≥ 6 months after treatment), the pulmonary function test of each patient was assessed using spirometry as obstruction, restriction, mixed pattern or normal and in obstruction, the severity of obstruction was assessed as mild, moderate, severe, very severe based on GOLD criteria.
Results: In our study, 84% of patients had abnormal lung function, with obstruction as the predominant abnormality in 36%, 21.8% demonstrated restrictive abnormalities, and 26.1% showed mixed patterns. Among individuals with obstructive lung disease, the severity of obstruction was assessed based on their post-bronchodilator FEV1% according to GOLD grades for COPD. It was observed that 67.4% had moderate obstruction. The mean FEV1 for the moderate obstruction group, the most prevalent among obstructive cases, was 1.41 litres.
Conclusion: Patients with a history of pulmonary tuberculosis in the past, often present with signs of permanent impairment in lung function, which may manifest as obstruction, restriction, or a mixed pattern. Tuberculosis is an independent risk factor for the development of obstructive airway diseases
CASE REPORT CREST Syndrome: A Rare Cause of Chronic Upper-Gastro Intestinal Haemorrhage in Adults
No full textABSTRACT:
Background: CREST syndrome, a limited cutaneous variant of systemic sclerosis, rarely presents with chronic upper gastrointestinal haemorrhage. This case report explores the complex pathological mechanisms and management challenges of this uncommon manifestation.
Case Presentation: A 52-year-old female with established CREST syndrome presented with recurrent melena and hematemesis. Comprehensive clinical evaluation revealed extensive gastrointestinal telangiectasia with significant bleeding potential. Upper endoscopy demonstrated multiple fragile vascular lesions throughout the esophagus, stomach, and duodenum.The patient underwent detailed diagnostic imaging, including CT angiography and capsule endoscopy. Therapeutic interventions included argon plasma coagulation, tranexamic acid therapy, and systemic immunosuppression with mycophenolatemofetil
Role of Yoga Prana Vidya (YPV) system as complementary medicine in the successful treatment of HIV: A case research study: YPV -HIV case research study
Full text linkIntroduction: The human immunodeficiency virus (HIV) is a pathogen that compromises the body\u27s immune system by targeting white blood cells known as CD4 cells. Studies show evidence of successful YPV therapy as complementary in the healing cases of dreaded diseases like cancer, and various other diseases. This paper presents an in-depth case study of a HIV patient treated successfully using YPV protocols as complementary medicine to overcome psychological issues and side effects of ART medication.Method: An in-depth Case study method is used, collecting case details from the Trainer-healer, medical information from patient, and a qualitative research interview of the patient transcribed for thematic analysis.Results; The CD4 figures for the period 2016 to 2022 show fluctuating results (above and below 500 cells /mm-cube) when ART medication was used alone. However, for the period 2022 to 2024 when the patient was treated complementarily using YPV protocols together with ART medication, CD4 values show a stable and rising pattern, above 500 cells/mm-cube. The medical team reduced dosage by 41%. Qualitative analysis shows he is not experiencing any side effects of ART medication, while feeling strong and energetic functioning normally.Conclusions: In addition to medical care, HIV patients require effective psychosocial assistance. A higher quality of life and longer lifespan are possible for individuals living with HIV who have access to timely diagnosis, treatment, and psychosocial support. According to this study, the YPV protocols provide efficient ways for patients to heal and rehabilitate. Recommendations include conducting more studies using right samples and methodology.