International Journal for Innovation Education and Research (IJIER)
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    IN SILICO EVALUATION OF POTASSIUM USNATE: A COMPOSITE PROMISER IN THE COVID-19 COMBAT

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    A new coronavirus appears in China in December 2019, subsequently threatening the world, it was identified as Covid-19. Its main symptomatic characteristic is directly linked to acute respiratory failure, however there are asymptomatic cases of the disease, mainly in the group not considered at risk. For the treatment of the disease a variety ofantiviral drugs have been tested, with conflicting results. The use of computer-assisted drugs is essential for the development of new therapeutic alternatives for various diseases, once they reduce the time consumed in the initial screening tests, in addition to determining the possible mechanisms of action and reducing toxicity. In our study, we evaluated the interaction of viral components of the coronavirus with potassium usnate, salt derived from lichenic origin and with proven antimicrobial and antitumor activities. Derived from ussic acid, potassium usnate showed low energy for complex formation, this interaction occurs between the usnate salt and the structures of proteinase 3CLpro and enzyme Mpro, all key parts of Covid-19. In addition, in order to prove in silico the use of potassium usnate, they were tested and compared with other approved drugs and candidates for clinical trials to combat the new coronavirus

    The resignification of medical practices based on contact with the Other - with indigenous and caboclo-riverside residents: An experience report in the Amazon

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    Introduction:The Amazonas' State University provides Nursing, Medicine, Dentistry, and Pharmacy degrees with the experience of Rural Training in Public Health. Two MD students had high expectations of experiencing health care in the Amazonas interior, as they realized that there was a lapse in their academic training. They questioned the fact that they were about to take the place of "doctors trained by the state of Amazonas" without knowing the population, ethnocultural and geographical variety of the region. This lack encouraged the choice of the location of the internship to be the city of São Gabriel da Cachoeira. Methods:Meetings and lectures were held with health teams that enabled clinical experiences and interactions with indigenous and riverside residents. Finally, seminars/activity reports were produced, which contributed to the awakening of reflections on medical practices. Thus, this experience report is based on the particular apprehension of the reality described, based on daily observation. Results and Discussions: During the internship, the students began to question and deconstruct the doctor-user relationship hierarchy. Conclusions: Thus, they re-signified their practices beyond technical and biological knowledge, in line with the decolonial epistemology

    White uniform’s meanings for nursing teachers

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    The uniform can be understood as a symbol which represents the individual’s occupation in society and in the institution where he works. Nursing, since its early days, is a profession which demands the wearing of a uniform. Nursing schools, traditionally, are in charge of indicating the wearing of uniform, informing this clothing’s symbolic importance for the profession. The present paper aims at analyzing the uniform’s meanings revealed by nursing teachers at a high school and nursing technician course, in a school located in the North Zone of São Paulo, Brazil. This qualitative research with semi structured interviews and participant observation with nursing teachers. The results showed that there are meanings that update traditional values related to the profession, the feminine gender, professional identity and the association between uniform and painful experiences

    Perception of Organizational Support in the Superintendence of Management of Public Administrative Expenses of the Government of the State of Rondônia

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    This research was motivated by the need to identify what is the relationship between organizational support provided by the Superintendence of the Public Administrative Expenses Management – SUGESP to its servants, the perception of servants of this support and to the concepts of sustainability. The general objective is to assess the relationship between the organizational support offered by SUGESP and the perception of employees. Theoretical aspects were addressed, such as the theory of Organizational Support, the conceptualization of the importance of employee satisfaction for the success of organizations, the Theory of Organizational Support, concepts of Public Administration and sustainable development. The methodology employed is quantitative approach, the search strategy used was the case study and study procedures were done through document analysis. Data collection was carried out by applying a self-administered questionnaire to a sample of employees working at SUGESP, as well as with the managers of the Superintendence. At the end of the research, it was identified that the average responses from the interviewed employees point out that they are indifferent to the perception of organizational support, while the manager, in the direct affirmative questions, identifies that the support offered is indifferent.  In the inverse affirmative questions, he agrees that there is effective support. It was also identified that approximately 56% of the employees do not have a clear understanding of the concepts of sustainability, a fact that influences the achievement of objectives and goals defined by managers

    Teachers’ primary concerns in a case of educational innovation introduction in primary schools in Greece

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    By converting all-day primary schools of suburban and urban areas in Greece into schools that implement the Comprehensive Reformed Educational Programme (CREP), a set of innovations were implemented, significantly altering the Greek school. The purpose of this study was to investigate the effect of selected variables over concerns of teachers who work at such schools. Additionally, this research asked the teachers to identify the professional development support and interventions required to enable them to make better use of the Book-reading Advancement (Philanagnosia) Activities innovation. Teachers’ administrative and pedagogical guidance executives, based on the above, will design the necessary interventions to positively address teachers’ concerns and implement the specific innovation in the most effective manner. Overall, the study found that higher teacher concerns were task related, with a significant record of information and self-concerns, which may indicate that the introduction of the innovation was not properly designed to address teachers’ primary concerns

    Epidemiological, Sociodemographic And Clinical Profile of Men With Cancer in Rondônia, Brazilian Amazon

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    Objective: to analyze the epidemiological, sociodemographic and clinical profile of men in Rondônia, Western Amazonia (Brazil), diagnosed with the main types of cancer, during a period of 2 (two) years. Materials and Methods: it is an epidemiological, descriptive, cross-sectional and quantitative study, with the systematization of primary data according to the methodological model recommended by Paraguassu-Chaves et al [6]. We used an instrument developed by Paraguassu-Chaves et al [5], semi-structured composed of a series of epidemiological, clinical and sociodemographic variables. The research project is in compliance with Resolution 196/96 of the National Health Council of Brazil, taking into account the ethical aspects of research in Brazil. Main results: the 10 (ten) main types of cancer diagnosed by the location of the primary tumor in men were analyzed, corresponding to 1,163 (74.9%) cases of cancer in men, over a period of 2 (two) years. The 10 (ten) most common types of cancer in men were: prostate (30.9%), non-melanoma skin (22.9%), stomach (11.7%), bronchi and lungs (6.7%), colon (5.8%), leukemia (5.8%), esophagus (4.4%), central nervous system (4.2%), rectum (3.9%) and bladder (3.6%). The age group of 50 to 79 years old reaches 76.4% of the 10 main types of cancer in men. They are more frequent in brown (64.6%) and white (28%) men and with low education. 73.2% of men with cancer are married. 44.9% of men with cancer work in agriculture. 45.6% of men with cancer have a family history of cancer. The sum of smokers and ex-smokers reaches a relative frequency of 43.7%. 19.5% consume alcoholic beverages and 17.2% are ex-consumers. In 40.1%, "other isolated therapeutic procedures" were applied in the first treatment. 14.2% of diagnosed patients died from the disease. Conclusions: The scenario of cancer projection in men in Rondônia is worrying and requires an urgent redirection of actions and strategies for cancer prevention, control, assistance and treatment

    Satisfaction of Individuals with Physical Disabilities Regarding the Use of Assistive Technologies

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    Background: The individual's personality and social factors influence a person's desire or ability to use assistive technology devices. Therefore, these components contribute to a positive or negative influence on the use of assistive technology and on the degree of satisfaction with the use.Objective: The aim of the study was to evaluate levels of satisfaction of individuals with physical disabilities with their prescribed piece of assistive technology. Methods: A quantitative questionnaire survey using The Quebec User Evaluation of Satisfaction with Assistive Technology 2.0. Data collect took place from August 2018 to April 2019, in the Physiotherapy Clinic of a Community University, in the Specialized Center for Physical and Intellectual Rehabilitation II and in the support networks for individuals with disabilities, such as: Roda Solta, Association for Supporting Families of Impaired People, Association of Disabled People and athletes of the women's Paralympic Handball Championship. Results: Fifty-six individuals with physical disabilities between 20 and 80 years old participated in the research, 27 women (48.2%) and 29 men (51.8%).The results suggested  that individuals are quite satisfied with their piece of assistive technology M=3.56(SD=1.09) and more or less satisfied with the professional services provided M=3.28 (SD=1.34). Among the 12 items considered most important by the participants, durability of the resource (54%) prevailed, followed by comfort (28%) and safety (24%).Conclusions: The dissatisfaction of individuals with physical disabilities was evident both in issues related to the resource and in the area related to the professional services, in relation to the resources. It needs to be adapted to the user’s needs, always aiming to improve health condition and quality of life

    Evaluation of the quality of wood from naturally fallen trees in the central Amazon

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    The objective of this study was to assess the quality and potential of wood from naturally fallen trees in the forest for product development and to provide subsidies for the use of raw material. The inventory of fallen trees was carried out along the road from the Experimental Station of Tropical Silviculture of the National Institute for Research in the Amazon (EEST / INPA) - Nucleus ZF-2, at km 23 of the ZF-2 road that starts to the left of km 50 of Highway BR-174 (Manaus-Boa Vista).  Only trees that had fall characteristics due to natural factors, that is, that had exposed roots, were considered for the inventory. It was also stipulated as a requirement for measurement the diameter class of trees of 25 cm ≤ DBH ≤ 45 cm. From each naturally fallen tree, the diameters (largest and smallest) and their length were measured. 5cm thick discs were removed from the trees to obtain samples for scientific identification of the wood and determination of physical properties. Based on the inventory, it was identified that many of the trees naturally fallen in the forest are in good conditions of use, considering their woody material and their volume. The Alexa grandiflora species presented the highest volume with 2,788 m³ for a single tree, followed by the species Ormósia sp. with 2,287 m³ and Protium tenuifolium Engl with a volume of 1,269 m³. Regarding the health of the inventoried trees, all from the species Byrsonima crispaJuss. had no sign of degradation, followed by the species Croton lanjouwensis and Ingá sp. The most frequent class was medium density with 9 species with a variation of 0.47g/cm3 to 0.62g /cm3. Eperua schomburgkiana Benth was the most dense with 0.78g /cm3.The levels of degradation found and the intrinsic characteristics of the species did not compromise the possibilities of using this wooden product, and can represent an excellent opportunity for economic return, contributing to minimize the pressures exerted around the living forest

    Violent deaths and the path to judicialization of LGBTphobia in Brazil: The (non) guarantee of protection of rights

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    This exploratory research was based on bibliographic and documentary sources and aimed to address the performance of the three branches regarding the criminalization of LGBTphobia. These people are stigmatized because of their sexual orientation and gender identity, since they differ from the heteronormativity still prevailing in society, which has led them to suffer more and more different types of violence, including physical, sexual, emotional, and psychological aggressions, to which they are constantly subjected. The lack of official data, beforehand, shows the real neglect of the public authority towards the rights and guarantees of this minority, in addition to the lack of effective public policies and non-investigation and non-judgment of crimes commonly poignant, which reveal true state violence. It was found that few actions by the executive branch go beyond the planning stage and that the endless discussions by the legislative can be described as true inertia, resulting in numerous quarrels in the judiciary branch, in which the LGBT community has achieved progress in denouncing human rights violations and in the relentless search for overcoming discrimination

    Yield parameters and water productivity of tropical and overseeded winter forages

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    Intensive pasture exploitation with tropical forages is one of the most efficient forms ruminant production. However, the results depends on the knowledge about these forages and the experience in its management. The objective of this work was to evaluate water productivity (WP) and yield parameters of Megathyrsus maximum cv. Mombaça “Guinea grass” and Cynodon spp. “Bermuda grass”, in single culture and overseeded with oats + ryegrass in autumn/winter period. Irrigation management was done considering a depletion factor of 0.3 (70% of the humidity the field capacity). The experimental design was a randomized complete block design with four replications, in which the forages are the treatments with evaluation at the time of the cycles. For all evaluated parameters, the best results were obtained with the Guinea grass in exclusive cultivation. The TFP (Total Forage Productivity) of Guinea grass was superior to Bermuda grass (59.3 and 30.2 Mg ha-1, respectively), in accordance with its average LAI (Leaf area index) values of 4.8 and 2.5, respectively. The most efficient use of water occurred for Guinea grass in exclusive cultivation, and the intercropped crops did not present increases in the WP. In the autumn/winter period, the accumulated TFP of the exclusive crop of Guinea grass was higher than the other crops. However, the SDM of Bermuda grass was higher than the other crops. In winter, the highest LAI occurred in Guinea grass in exclusive cultivation, followed by the overseeded Guinea grass, 4.8 and 4.5, respectively. Consortia did not increase forage yield during the winter. The consortiums did not increase forage yield during the winter

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