OJS [Pandawa Inst.]
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75 research outputs found
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Antibacterial Effect of Juglans regia, Citrus sinensis, Vicia faba, and Urtica urens Extracts under In vitro Conditions
No full textVarious agricultural products are known to have anti-microbial, anti-cancer, and anti-inflammatory effects. As we can mention, Walnut (Juglans regia) husk, orange (Citrus sinensis) peel, Broad bean (Vicia faba) peel, and Nettle (Urtica urens) are proven to have antimicrobial and anticancer actions. Also, plant diseases such a Pectobacterium carotovorum, Ralstonia solanacearum, Dickeya chrysanthemi, and Pseudomonoas syringae are known to cause annual damage to plant products. Therefore, in the current study, the researchers evaluated their antibacterial activity on the mentioned bacteria under in vitro conditions. Extracts of J. regia husk, C. sinensis peel, V. faba outer peel and U. urens were prepared by maceration method and their anti-bacterial activity on P. carotovorum, D. chrysanthemi, P. syringae, R. solancearum was evaluated using blank disk and well diffusion to obtain minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values. J. regia (husk) and V. faba (outer peel) extracts revealed an anti-bacterial effect on all 4 studied bacteria, while C. sinensis (peel) only inhibited the growth of P. syringae and U. urens only had this effect on P. syringae and R. Solancearum. The inhibition zones varied from 8 to 14 mm, while almost all MIC and MBC rates were 6.25 and 12.5 mg/mL, respectively. Based on the antimicrobial results, the extracts that showed suitable antibacterial effects on certain bacteria can be further studied to be used as natural pesticides
Essential Oils: A “Potential Green” Alternative in Pharmaceutical, Nutritional and Agricultural Sectors
No full textIn the era of modern medicine, the therapeutic use of plant-derived essential oils has been one of the fascinating fields of study for researchers around the globe. The plant-derived essential oils, which are a combination of volatile organic compounds may be used as a substitute for the treatment of pathogenic microbes. The antimicrobial properties of essential oils are extremely diverse. In microbial infections, essential oils create an electrochemical gradient across the cell wall which intervenes with ATP synthesis and can also disrupt the electron transport system (ETS) by rupturing the mitochondrial membrane. Many essential oils have antiviral properties that can effectively treat COVID-19. The purpose of the current review is to shed light on the antimicrobial efficacy of essential oils. A survey of the methods used for the determination of the interaction and mechanisms involved in the antimicrobial activities of essential oils are also reported as well and the applications of essential oils could be interesting COVID-19 therapeutic options because of their pharmacological actions. This review will attract the attention of researchers to optimize and elucidate the use of essential oils as green alternatives to treat the deadliest infectious diseases in living organisms
Composition of Stand and Growth Dynamics of Black Cardamom (Amomum subulatum) in Different Agroforestry Habitats in Bhutan
No full textThe composition and arrangement of tree species at different altitudes play a vital environmental role in the growth of Black Cardamom (Amomum subulatum) in Bhutan. The present study assesses agroforestry tree species composition and factors affecting the growth of A. subulatum in different habitat types. Altitudes were sorted into three different altitudinal bands (low, mid, and high) and each altitudinal band in three different habitats (timber tree, fodder tree, and mixed tree habitat) was assessed. The sampling of 48 plots was made for each habitat and the plot size was 20×20 m. In total, 144 plots were sampled systematically within the selected altitudinal bands in three different habitats. The 56 ecologically important agroforestry shade tree species were used for growing A. subulatum. Tree species preference of A. subulatumchanged based on different altitudes and habitat types [F(2, 33) = 45.672, P = .001]. Critical factors affecting the growth are tree canopy cover (r = –0.461) and infested A. subulatum stems (r = –0.765). The increasing number of infested stems retarded the growth and dense canopy cover or open canopy reduces the growth rate of A. subulatum. Overall, growth was suitable in timber tree habitat at mid altitudes, where Alnus nepalensis was the dominating species having 41.40% canopy cover with low pest and disease-infested A. subulatum stems. Significantly, the lower altitudinal band and the fodder tree habitats were found to be unsuitable for growth (p < 0.05). Thus, appropriate site selection, canopy cover and altitude could provide optimum growth
The Potential of Moringa Leaf Nanoparticles (Moringa oleifera) on the Expression of TNFα, IL10, and HSP 27 in Oral Cavity Cancer
No full textOral cancer is currently the sixth leading malignancy in the world, with over 330,000 cases resulting in death. Several cytokines and proteins protect the survival of cancer cells, such as TNF-α, HSP27, and IL-10. Moringa oleifera is an herbal medicine with anti-cancer properties. Nanoparticles of M. oleifera have the property to be easily absorbed by water-soluble cells, so only small doses are needed to be used as anti-cancer ingredients. This research aims to prove the ability of M. oleifera nanoparticle extract against oral cancer through the expression of tumour necrosis factor α (TNF-α), heat shock protein (HSP27), and interleukin 10 (IL-10). Rat as non-human experimental subjects were divided into four groups: control group (K), treatment group 1 (P1), treatment group 2 (P2), and treatment group 3 (P3). Cancer induction was carried out by injecting with benzo[a]pyrene, and then M. oleifera nanoparticle extract was administered in three forms of treatment doses of 125 μg/mL (P1), 250 μg/mL (P2), and 500 μg/mL (P3). Immunohistochemical examination was analysed through TNF-α, HSP27, and IL-10’s expression. The expression of TNF-α and HSP27 between control and treatment groups was significantly different. P2 had the lowest expression of TNF-α and HSP27. The expression of IL-10 between control and treatment groups was also significantly different. P1 had the lowest expression of IL-10. M. oleifera nanoparticle extract can reduce oral cancer progression by decreasing the expression of TNF-α, HSP27, and IL-10
Impact of Feed Point Position on Patch Antenna’s Return Loss and Bandwidth for UWB Applications
No full textThe demand for compact, lightweight, and high-performance antennas has increased in recent times in the communication industry. Microstrip patch antenna (MPA) becomes a better choice to effectively fulfill these requirements. In this study, hybrid techniques of partial ground plane, slotted patch, and defective ground structure are employed in MPA design to reduce the return loss, good impedance matching, and increased the bandwidth, gain, and efficiency of the antenna. This research demonstrates the impact of altering the feed point position, a crucial phenomenon of antenna design, on the patch antenna and determines the proper feed point location by comparing a minimum return loss (S11) which achieves the highest performance for the designed antenna. High-frequency structure simulator (HFSS) software is used to design and simulate the patch antenna. The operating frequency of the antenna is 6.85 GHz for UWB applications (3.1–10.6 GHz). A FR4 epoxy substrate material with dimensions of 30 mm × 20 mm is used to design the antenna. It has a dielectric constant of 4.4, a thickness of 0.8 mm and a tangent loss of 0.02. Multiple resonant frequencies are observed with different return losses for each feed location. The analysis shows that the finest feeding point is found at the center of the patch (9, 0) with a very low return loss (-28.35 dB), and a high impedance bandwidth (19.7 GHz). The antenna also achieved a gain of 4.46 dB, a directivity of 4.6904 dB, and a radiation efficiency of 95.90%. Hence, the location of the feed point can be considered as an influential factor in the antenna design
An Analytic Solution to The Inhomogeneous Verhulst Equation Using Multiple Expansion Methods
No full textThe present study aims to obtain an analytic solution for the inhomogeneous Verhults equation using multiple expansion methods. This study identifies the external factors represented by the inhomogeneous term that determine optimal variable conditions for ecosystem population growth. The simulation involves scenarios that utilize constant growth rates, periodic growth rates, constant external factors, and periodic external factors. It is found that external factors increase population growth, whereas constant external factors prevent growth under saturation conditions. Periodic external factors cause fluctuations in the amplitude of growth regions. The present study will highlight and discuss the development and application of the solution
Binomial Method in Bermudan Option
No full textThe Bermudan option allows the contract holders to make and buy a hybrid contract between American and European options. Bermudan option contract can be executed at certain times until the due of the contract. The purpose of this research is to determine the price of the Bermudan option using the binomial method, and then to compare the binomial method result of n steps with the market option price. In determining stock prices at each point, there will be two branches of the binomial method: up and down branches. These branches represent the movement of stock prices in the market. The result shows the price of Bermudan option is convergent at a certain value when the binomial procedure is enlarged. The comparison of the Bermudan option price using a binomial method to the market price shows that the price of Bermudan option is an approach to the market price in certain conditions. Empirically, the price of Bermudan call option is in approach to the market option price or has a minimum error when the exercise price is below the current stock price. The price of Bermudan put option empirically is in approach to the market option price or having a minimum error when the exercise price is above the current stock price
Application of Response Surface Methodology (RSM) to Study Transesterification of Palm Oil in the Presence of Zeolite-A as Catalyst
No full textIn this research, the application of response surface methodology with central composite design (RSM-CCD) to optimizetransesterification of palm oil in the presence of zeolite-A as catalyst was investigated. Zeolite-A was synthesized from rice husk silica (RHS) and food-grade aluminium foil using hydrothermal method and then characterized using XRD and SEM. The synthesized zeolite was then applied to an optimized transesterification reaction using response RSM with three factorial levels, for three variables including methanol to oil ratio, catalyst load, and reaction time. The experimental results indicate that the yield of 99% was achieved at optimum conditions of methanol to oil volume ratio of 6, catalyst load of 9.6%, and reaction time of 4.3 hours. The results of experiments and predicted results based on the RSM model are in agreement as shown by the p-value less than 0.05 at a confidence level of 95%
Cytotoxic Activity of Green Seaweed Halimeda tuna Methanolic Extract Against Lung Cancer Cells
No full textLung cancer is a malignant tumor that attacks the lungs generated by carcinogenic free radicals such as cigarette smoke. Seaweed contains bioactive compounds that have the potential to reduce cancer-causing free radicals. This study aimed to determine the phytochemical content and cytotoxic activity of Halimeda tuna seaweed extract against lung cancer cells (A549). The H. tuna sample was macerated using methanol for 24 h. Cytotoxic test of H. tuna crude extract used the MTT test against A549. The crude extract was phytochemically tested and analyzed using gas chromatography–mass spectrometry (GC-MS). The results showed that the H. tuna crude extract had cytotoxic activity against A549 with an IC50 value of 2771 µg/mL. The phytochemical test showed that H. tuna crude extract contained flavonoids and steroids. showed the presence of fatty acid compounds including palmitic acid, oleic acid, myristic acid, palmitoleic acid and stearic acid. Based on the results can be concluded that H. tuna extract had cytotoxic activity against A549 with low cytotoxicity to be used as a chemo-preventive agent
Integration of Rational Functions
No full textA rational function can always be integrated, that is, the integral of such a function is always an elementary function. The integration procedure is complex and consists of four steps: elimination of the common zero-points of the numerator and denominator, reduction to a true rational function, decomposition into partial fractions and integration of the obtained expressions using direct integration, substitution method or partial integration method. Integrating rational functions is important because integrals of rational functions of trigonometric functions as well as integrals of some irrational functions are reduced to integrals of rational functions by appropriate transformations