Himalayan Journal of Health Sciences (HJHS)
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Critical Analysis of Ashmari
Ashmari is the third most common and unpleasant urinary tract condition. The Ashmari stone's shape is comparable to the urolithiasis symptoms. Traditional signs of Ashmari include discomfort and urine obstruction. Acharaya Sushruta described it as one of the eight Astamahagadas, or illnesses, that are the most difficult to treat. It is among the most prevalent diseases that the Mutravahasarotas experience. The urolithiasis recurrence rate is close to 50%, even with current treatment options. Since urolithiasis is thought to be spreading over the globe at an increasing rate. The idea of urolithiasis is examined in this article from an ayurvedic perspective in order to better management of disease
Method Development and Validation of Fluconazole and Ivermectin in pure and Combined Dosage form using UV by Q- absorption ratio and Vierotd’s method
Multicomponent analysis involves simultaneous estimation of drug substances in combined dosage form. A comparative study between Q-Absorption ratio technique and Simultaneous Equation Method has been established for effective implication of the developed method. Numerous trials were performed as a part of solvent selection, both the drugs under study Fluconazole (FLN) and Ivermectin (IVR) have shown good solubility in methanol (Spectroscopic Grade). The absorption maxima (λmax) were found to be 261nm for FLU and 245nm for IVR respectively. Both the drugs were showing same extinction coefficient (Isosbestic point) at 261nm. A comparative study is proposed to be established for simultaneous equation and Q-absorption ratio method. Between the concentration and absorbance, calibration curves revealed a linear relationship. The regression line equation was established and identified r2 for Fluconazole and Ivermectin is 0.999 and 0.999. Fluconazole and Ivermectin were assessed by the validated method when each of the drug individually subjected to various stress conditions like concentrated acidic, basic, peroxide, excessive light and thermal. For estimation, the suggested approach was used for drug content in locally available marketed formulations which has proven successful for routine analysis of the same with the application of vierotd’s as well as Q-absorption method
Implantable Drug Delivery Systems
Traditional drug delivery methods provide very little, if any, control over the timing and pattern of drug release Medication concentration absorption at the point of action. Undefined medication concentration in plasma is a typical and obvious issue with the traditional dose method. Thus to overcome such problems efforts have been made by researchers and pharmaceutical scientists to the betterment of the drug delivery system and that lead to the development of the Novel Drug Delivery System (NDDS). NDDS is the approach and technology to deliver the drug in low concentration and follow the zero-order release of the drug in a controlled manner. Additionally, the NDDS's development results in the creation of an implantable drug delivery system (IDDS). a system for implantable medication delivery is a new approach of medicine delivery In this technique, the medicine is delivered under controlled conditions to the precise location where the implant is placed. The formulation, preparation, evaluation criteria, and future aspects of the implantable drug delivery system are the subjects of this study
Diagnosis of Krumi on the Basis of Sanjat Krumi Lakshana: A Case Report
Worm infestation is the most common pediatric complaint which results in various health issues in children. Vedic literature also approves the presence of Krumi in children. Due to the resemblance of meaning and clinical features, worm infestation is commonly correlated with the Pureeshaja Krumi, which is one of the three types of internal Krumi. Ayurveda also gives common clinical features of Krumi which includes fever, pain in abdomen, skin discoloration, nausea, aversion to food, loose motions and giddiness, etc. This group of symptoms is not correlated with any clinical condition yet. Hence an effort is made here to present a case of Krumi with the classical features of common manifestations
Classification, Causes, Pathogenesis and Ayurveda Management of Avarana
Avarana is disease related concept of Ayurveda; that play role in the pathogenesis of various diseases. The management of Avarana also play key role in the successful treatment of disease. Avarana mainly involve vitiation of Vata which is self-generated and acts as triggering factors for many ailments. The Avarana itself means Avarodha that is also referred as Gatinirodha. Ayurveda described various types of Avarana or Avarana Vatas depending upon Avruta and Avaraka. Avruta means getting obstructed and Avaraka causes obstruction. The proper diagnosis and management of Avarana Vata is prerequisite since wrong diagnosis may lead to faulty treatment plan that may further deteriorate the pathology. The proper knowledge and diagnosis of Avarana is important for physician to attain Chikitsa Saphalyata. This article made an attempt to describe classification, causes, pathogenesis and Ayurveda management of Avarana
A Review of an Ayurvedic Polyherbal Formulation Rajanyadi Churna
Rajanyadi Churna is a very popular drug between Ayurveda consultants dealing with children. Vagbhata has described this drug under Balaroga in the management of Dantodbhedajanya Vyadhi. It is useful in various conditions arising during primary dentition in children. It is also said that Rajanyadi Churna can be used in all types of diseases arising in children due to its Agni Deepana properties. The present review tries to explain the properties of Rajanyadi Churna and its usefulness in Dantodbhedajanya Vyadhi along with its clinical significance
Ayurveda and Modern perspective on Food Poisoning and its Medical Management
Food poisoning, also known as food borne illness, arises from consuming tainted food, with infectious agents or their toxins contaminating the food at any stage of processing. Mishandling or improper cooking at home can also lead to contamination. Symptoms include vomiting, nausea, diarrhea, stomach discomfort and fever. In Ayurveda, the body's equilibrium is governed by three Doshas; Vata, Pitta and Kapha. Disproportion in any of these Doshas can result in ailments. Aalsak and Visuchika are Ayurvedic conditions akin to food poisoning, preventable through a balanced diet and lifestyle. Ayurveda also suggested some drugs such as; Hinguvachaadi Choornam, Dashamoolarishtam, Hinguvachadi Gulika and Dhaanwantharam Kashaayam, etc. to address condition of food poisoning. Present article discussed Ayurveda and modern perspective on food poisoning and its medical management
Garbhsanskar Guru App: A Comprehensive Cross-Sectional Study on Pregnancy Outcomes and Maternal Well-being
This whitepaper provides an in-depth analysis of a cross-sectional study on the Garbhsanskar Guru app, focusing on its significant impact on pregnancy outcomes and maternal well-being. Involving 1,323 mothers who practiced Garbh Sanskar through the app, the study collected data through a postnatal survey, revealing positive influences on baby's birth weight, delivery timing, and maternal stress and positivity levels. The results demonstrate the app's effective role in enhancing pregnancy outcomes and maternal mental health
Physiology of Digestive System w.s.r. to Avastha Paka: an Ayurveda Review
According to medical science, digestion is the process by which complex food is broken down into its simplest form. These all peculiarities happen in gastrointestinal area. According to Ayurveda, Dhatwagni, Jathragni and Bhutagni are responsible for breaking down complex food into its simplest monomers. The Agni assumes key part in this cycle hence legitimate working of Agni is essential for the stomach related physiology. Grahani or Pakvamashaya is considered as the site of Jathragni. The process of digestion is helped by various components like Kledaka kapha, Pachaka pitta and Samana vayu. Samana vayu stimulates the Pachakagni so that food can be separated, Kledaka kapha softens food, and Pachaka pitta helps in the digestion process. The absorption begins with the utilization of food and this cycle finished in three phases specifically Avastha paka, these phases of Avastha paka are Madhur avastha paka, Amla avastha paka and Katu avastha paka
Ayurveda Descriptions of Garavisha, Dooshivisha and Viruddhahara their Pathological Manifestations and Management
Visha is considered something that causes harm to all human being, the invasion of Visha in human body leads pathological manifestation. The Visha also becomes causes of death in some conditions if not treated properly. Ayurveda described various concept related to the Visha including Dushi visha, Gara visha and Viruddhahara. Dushi visha represents damaged and spoiled poison. The term Dushi itself means attenuated and denatured. These poison (Dushi visha) acts as latent toxin or exhibited cumulative toxicity inside the body. Similarly use of powder of insects can act as Gara Visha, the hazardous chemicals and incompatible diet also described as toxins in various medical texts. These all toxins lead acute or chronic illness in the body and Ayurveda mentioned several therapeutic modalities for treating pathological manifestations of Visha