Himalayan Journal of Health Sciences (HJHS)
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Descriptions of Ayurveda Samhitas and ancient Literatures on Microbial diseases w.s.r. to Janpadodhwans
Get PDFAyurveda the historical science of Indian medicine described various diseases and their management. Ayurveda described concepts of Bhoota–Graha Rogas as disease of microorganism which mainly arises when Sharir Bala get reduced. Currently such types of diseases creating great health burden since large number of global population affected with pathogens. Ayurveda described causes, transmission mode and prevention of such pathological conditions under the heading of Janpadodhwans. Acharya Charak mainly emphasizes concept of Janpadodhwans as Sankramak roga. The various literatures of Ayurveda described concept of Janpadodhwans / Sankramak roga. Present article dealt with ayurveda perspective on Janpadodhwans with respect to various Ayurveda philosophers
Concept of Gouty Arthritis (Vatarakta) in Ayurveda
Get PDFThe understanding of ideal definition of health and dhatusamya is very essential for human beings in order to attain the first pursuit of life for attaining hita-ayu and sukha-ayu. In Ayurveda health means the state of Doshasamya, Agnisamya and Dhatusamya as well as wellness of Atma, Indriya and Mana. Acharya Charaka says that a man desirous of happiness should observe the rules which are related with the prevention of unborn diseases and the cure of those which have already arisen. The ultimate aim of life is to achieve the Dharma, Artha, Kama & Moksha. For obtaining the above-mentioned goals, it is very essential to be fit physically, mentally and spiritually. So, directions of the Ayurveda in this regard should be followed strictly. When the person does not follow the directions of Ayurveda in regard to Ahara, Nidra, Brahmacharya collectively known as “Tri-upstambha” the person becomes ill. Improper use of the above three supports of life is the cause of so many diseases takes place, out of them, one is the Vatarakta (Gout), which consists of swelling including burning pain in metatarsophalangeal joints initially followed by the other joints, resulting in inability to the walk
PCOS; Modern and Ayurveda Review W.S.R. to Complication and Management of Bija Kosha Granthi
Get PDFAyurveda has given prime importance to women health and presented therapeutic approaches for managing common gynecological disorders, Poly Cystic Ovarian Syndrome (PCOS) is one such common health issue associated mainly with women of reproductive age group. The incidences of Poly Cystic Ovarian Syndrome (PCOS) increases day by day due to the adverse effects of life style of current scenario. The modern life style imparting physical as well as mental stress which causes pathological events like PCOS. The condition of PCOS mainly associated with other gynecological conditions like; Alpa artava, Anartava and Asrikdosha. The PCOS on the basis of sign and symptoms comes under heading of Aartavadushti & Yonivyapadas. Pathologically disease possesses hormonal imbalances along with Dhatus Dushti which resulted cysts in ovary. Uses of herbs, ayurveda formulations and Shodhna-Chikitsa, etc. are some Ayurveda measures utilized for the management of PCOS. Considering these all aspects this article presented Ayurveda perspective on PCOS W.S.R. to complication and management of Bija Kosha Granthi
Nanotechnology based approaches to fight against COVID 19 infection
Get PDFNanotechnology, the study of nanoparticles, is emerging as a leading pharmaceutical technique. It is used in various fields of drug delivery, bioimaging, biomedical diagnosis, tissue engineering, production of formulation, medical devices and many others, thereby playing a key role in future pharmaceutical and pharmacotherapy production. The ability to modify molecules and supramolecular frameworks for the development of devices or substances with altered functions or features is the most significant benefit of this technology. Nanoscience provides a solution to the spread of COVID-19 infection by aiding in its detection, including surface antiviral coatings, protection of facemasks, increased personal protection services, airborne filtration and therapeutic administration. Addressing the numerous clinical and wellbeing issues that have arisen as a result of the global dissemination of coronavirus infection. This study explores in depth the different uses of this technology in combating the pandemic situation of COVID-19 with an insight into the creation of a chemically engineered nanodevice that prevents its proliferation in the host cells. Low medication loading capability, low loading performance, and poor ability to monitor the delivery of sizes are the only problems with existing approaches. The use of nanotechnology, such as nanopatterning, could allow high loading efficiency and highly homogeneous particle sizes to generate nano / micro particles
Recent Research on Analytical Methods of Analysis of Artemether and Lumefantrine: a Review
Get PDFNew antimalarial tranquilize investigates are concentrating on promising focuses so as to grow new medication competitors. Essential digestion and biochemical procedure in the malarial parasite, for example Plasmodium falciparum can assume a vital job in the distinguishing proof of these objectives. In any case, the rise of protection from antimalarial drugs is a heightening far reaching issue with the advancement of antimalarial medicates improvement. The pharmaceutical enterprises are focused on new medication improvement because of the worldwide acknowledgment of this perilous protection from the right now accessible antimalarial treatment. The HPLC, UV and HPTLC techniques are accessible for the examination of Artemether and Lumefantrine the as of late utilized medication for malaria are surveyed in this article
Ayurveda Properties and Therapeutics Importance of Kumarkalyan Rasa: A Review
Get PDFAyurveda system of health restoration comprises many streams for the management of different diseases. Ayurveda encompasses several therapeutic options for different age groups and in this regards Ayurveda suggested many approaches for pediatric care (management of Balaroga). Balyavastha or childhood is stage of life which needs special care due to the lack of strength and immunity. Ahara, Vihara and Aushadhi are some Ayurveda measures which help to maintain strength in Balyavastha. There are many drugs (Aushadhis) mentioned in Ayurveda classics which provides therapeutic response in health issues of childhood age. Kumarkalyana Rasa is one such Ayurveda drug used as pediatric medicine. This drug used for breathing problems, fever, cough, jaundice, digestive problems, diarrhea and others problems in children. Present article emphasizes Ayurveda perspective of Kumarkalyana Rasa and its therapeutic significance in Balaroga
Cyclodextrins as a Drug Delivery Carrier for Anti-Cancer Drugs
Get PDFCyclodextrin “molecules are large with a number of hydrogen donors. Cyclodextrins are widely used as "molecular cages" in the pharmaceutical, agrochemical, food and cosmetic industries. In the pharmaceutical industry they are used as complexing agents to increase the aqueous solubility of poorly soluble drugs and to increase their bioavailability and stability. Chemotherapeutic treatment for cancer has limitations such as poor drug solubility, non-specificity, poor bioavailability and poor survival rate. The lack of efficient treatment has created the need to develop and implement novel technology based on combination strategy of cyclodextrin complexation and nanotechnology with a view to make the therapy more useful and acceptable. The review deals with cyclodextrin and its applications in anti-cancer drug delivery for cancer treatment
The formulation and evaluation of mouth dissolving tablet Levocetirizine by using synthetic Superdisintegrants
Get PDFAim of this research work was to develop mouth dissolving tablet that disintegrates rapidly in mouth by using tasteless complex of Levocetirizine and β-CD. Mouth dissolving Tablets also called as Orodispersible tablets. Formulated Levocetirizine β-CD complex was characterized by infrared spectroscopy, thermal analysis and X-ray diffraction pattern. Tablets were developed by direct compression method. Superdisintegrants like Sodium starch glycolate (SSG), Crosscarmellose sodium (CCS) and Crosspovidone (CP) were used for the formulation. Every formulation was subjected to in-vitro tests like wetting time, disintegration test and dissolution test. The in-vitro study showed that increasing the concentration of superdisintegrants lowers the wetting time (WT) and disintegration time (DT) and enhances the drug release percentage of the formulations.
The formulation CPX5 was the most effective formulation as it showed wetting time of 12 seconds, disintegration time of 20 seconds and cumulative % drug release of 41 and 99% at 1 and 10 minutes respectively. The study showed that the formulations containing SSG and CP as the superdisintegrants showed better drug release pattern than the formulations with other superdisintegrants. The study also showed that SSG as the superdisintegrant was more effective for the formulation of orodispersible tablets of levocetirizine dihydrochlorid
Anushastra Karmas in Shalya Tantra: An Ayurveda Perspective
Get PDFShalya Tantra is branches of Ayurveda that deals with surgical and parasurgical techniques for the management of various diseases. Shalya Tantra involves uses of various techniques or Karma to facilitate surgical or parasurgical interventions and Anushastra Karma is one of them. Anushastra Karma means uses of non-surgical instruments to perform surgical procedure. Agnikarma, Kshara Sutra, Jalukavacharana and Siravyadaha, etc. are some approaches of Anushastra Karma which mainly employed for the management of pathological conditions like; fistula, fissure and pilinoidal sinus, etc. The Anushastra Karma play vital role in surgical interventions, therefore in this article the various aspects related to the Anushastra Karma presented
A Review Study on Nidan, Srotodushiti and Srotodushti Prakara
Get PDFSrotas is unique structure of our body, innumerable and divided into two types Bahirmukhi and Antarmukhi Srotas. They are hollow, tubular and porous in nature which transports the essential nutritional elements for all the Dhatus. According to Ayurveda when Dosha, Dhatu and Mala are in the equilibrium state and Srotas also have remained in their natural state, then individual achieved good health status. The Srotas play an important role in physiology and the pathogenesis of disease because in normalcy stage, they regulate the physiology of the body and maintain the anatomical structures of Dhatus. The influences of aetiological factors on Srotas can results pathological manifestations. If Srotas get affected due to any reason then diseases may arises. Considering this fact present article exploring various aspects related to the Srotodushti Nidan and Prakara