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Ús no mèdic o ús inadequat de les benzodiazepines en els adolescents: revisió sistemàtica
Curs 2022-2023Resum
Objectiu: L’objectiu principal d’aquest estudi és revisar sistemàticament la literatura científica actual sobre l’ús no mèdic de medicaments receptats entre els adolescents focalitzant l’atenció en les BZD.
Mètode: La cerca es va fer en les bases de dades de Web of Science, PsycINFO, Pubmed i Scopus, mitjançant descriptors relacionats amb l’ús no mèdic, inadequat o recreatiu de les BZD en els adolescents. Seguint la guia metodològica PRISMA, els articles es van seleccionar a partir del títol, el resum i el text complet.
Resultats: Vint estudis van complir els criteris d’inclusió. En la majoria d’estudis analitzats (75%), s’observa que en general, la prevalença del consum no mèdic de BZD entre els adolescents incrementa de manera progressiva i preocupant amb el pas del temps. El 40% de les investigacions suggereixen que existeix més d’un motiu a l’hora de realitzar aquest consum, a ser: curiositat, experimentar o recerca de sensacions, col·locar-se o “get high”, dormir, relaxar-se, regular l’estat d’ànim, autotractar-se de diferent simptomatologia i/o incrementar els efectes d’altres substàncies psicoactives. El 60% dels estudis han identificat diverses variables associades al ús no mèdic de BZD: el 25% coincideixen en algunes de les variables demogràfiques dels adolescents (ser d’ètnia caucàsica, edat avançada, el nivell d’estudis, portar a terme diferents comportaments, consumir altres substàncies, ingressos familiars més baixos, etc.); el 40% identifiquen algunes variables psicosocials (percebre un risc de perjudici i o de gravetat baix per la salut, la disponibilitat del fàrmac, perfils més impulsius, ansiosos, depressius, presentar símptomes relacionats amb el suïcidi, haver sofert varis successos negatius en la vida, entre altres); el 20% expressen variables familiars implicades (obtenir els fàrmacs de casa, que els pares consumeixin de manera prescrita aquesta medicació, els tipus de relacions intrafamiliars); i el 40% consideren que les noies realitzen un consum no mèdic o inadequat de BZD més elevat que els nois. Totes aquestes variables s’associen positivament amb l’abús de BZD per part dels adolescents. Per últim, remarcar que el 85% de les investigacions examinades remarquen que el consum no mèdic o inadequat de BZD no es tracta d’un consum pur, sinó que sempre s’associa al consum d’altres drogues (alcohol, tabac, marihuana, etc.).
Conclusions: La complexitat de l’ús no mèdic o inadequat de les BZD en els adolescents pot presentar reptes pel desenvolupament de programes de prevenció i de tractament. A partir d’aquesta revisió sistemàtica es detecta la necessitat de seguir investigant per avaluar més a fons les vies de desviament de medicaments entre els adolescents, així com les motivacions i els factors associats al consum no mèdic de BZD, a fi de proporcionar una base empírica sòlida per poder establir programes eficaços de prevenció i d’intervenció.
Paraules clau: “adolescents”, “prescription drug misuse”, “nonmedical use”, “benzodiazepines”Abstract
Objective: The main objective of this study is to systematically review the current scientific literature on the non-medical use of prescription drugs among adolescents focusing attention on BZD.
Methods: The search was made in the databases of Web of Science, PsycINFO, Pubmed and Scopus, using descriptors related to the non-medical, inappropriate or recreational use of benzodiazepines in adolescents. Following the PRISMA methodological guide, articles were selected based on the title, abstract and full text.
Results: Twenty studies met the inclusion criteria. In the majority of studies analysed (75%), it is observed that, in general, the prevalence of non-medical use of BZD among adolescents increases progressively and worryingly over time. 40% of the research suggests that there is more than one reason for this consumption, namely: curiosity, experimenting or seeking sensations, getting high, sleeping, relaxing, regulate mood, self-treat different symptoms and/or increase the effects of other psychoactive substances. 60% of the studies have identified several variables associated with the non-medical use of BZD: 25% agree on some of the demographic variables of the adolescents (being of caucasian ethnicity, older age, the level of education, carrying out different behaviours, use of other substances, lower family income, etc.); 40% identify some psychosocial variables (perceive a risk of harm and/or low severity due to health, the availability of the drug, more impulsive, anxious, depressive profiles, presenting symptoms related to suicide, having suffered several negative events in life, among others); 20% express family variables involved (getting the drugs from home, the parents consumed this medication as prescribed, the types of intra-family relationships); and 40% consider that girls make a higher non-medical or inappropriate use of benzodiazepines than boys. All these variables are positively associated with adolescent BZD abuse. Finally, 85% of the researchers examined note that the non-medical or inappropriate use of BZD is not a pure use, but is always associated with the use of other drugs (alcohol, tobacco, marijuana, etc.).
Conclusions: The complexity of the non-medical or inappropriate use of BZD in adolescents can present challenges for the development of prevention and treatment programs. Based on this systematic review, the need for further research is detected to further evaluate the pathways of drug diversion among adolescents, as well as the motivations and factors associated with non-medical use of BZDs, in order to provide a basis solid empirical evidence to be able to establish effective prevention and intervention programs.
Keywords: “adolescents”, “prescription drug misuse”, “nonmedical use”, “benzodiazepines”Tutores: Alicia Leiva Mir i Anna Casellas Gra
Inclusión educativa y pedagogía Montessori
Curs 2022-2023Resumen
La presente investigación persigue acercarse a la respuesta que se da desde el método Montessori a la inclusión educativa y a la atención a la diversidad. La educación inclusiva promueve una enseñanza accesible para todos los niños y niñas que facilite entornos de aprendizaje flexibles partiendo del principio de equidad. Esta se fundamenta en el desarrollo de una educación que valora y respeta las diferencias concibiéndolas como oportunidades de desarrollo personal y social. Por su lado, la educación Montessori plantea la protección del desarrollo del individuo desde su nacimiento. Se trata de una educación basada en la vida como centro de su propia función en lugar de sentar las bases en programas preestablecidos. Se plantea una investigación basada en la revisión bibliográfica de fuentes especializadas en la educación inclusiva y en el método de la Pedagogía Científica, y en entrevistas a cinco profesionales Montessori. Encontramos que Montessori tiene en su naturaleza la atención individualizada que se necesita para implementar una educación inclusiva y que desde la óptica de este método pedagógico se tienen en cuenta las singularidades de cada niño/a al margen de su edad cronológica. Básicamente, el elemento clave y determinante en el que confluyen la pedagogía Montessori y la inclusión educativa es la respuesta educativa individual que da Montessori a cada niño y que es también requisito indispensable de una acción educativa inclusiva. Resulta revelador y enriquecedor tomar conciencia de la necesidad del trabajo en equipo que se debe dar en las escuelas y la importancia de estar actualizados en cuanto a formación en educación inclusiva y atención a la diversidad.
Palabras clave
Educación inclusiva, Montessori, diversidad, flexibilidad, individualidadAbstract
The present investigation seeks to approach the response that is given from the Montessori method to educational inclusion and attention to diversity. Inclusive education promotes an accessible learning for every child which facilitates flexible learning environments based on the principle of equity. It is based in the development of an education that values and respects their differences, seeing them as opportunities of personal and social development. For its part, Montessori education raises the protection of individual development from birth. It is about an education based on life as the center of its own function instead of laying the foundations in pre-established programs. An investigation is proposed based on the bibliographic review of specialized sources in inclusive education and in the method of Scientific Pedagogy, and in interviews with five Montessori professionals. We find that Montessori has in its nature the individualized attention that is needed to implement an inclusive education and that from the point of view of this pedagogical method, the singularities of each child are considered regardless of their chronological age. The key and determining element in which Montessori pedagogy and educational inclusion come together is the individual educational response that Montessori gives to each child, and which is also an essential requirement for inclusive educational action. It is revealing and enriching to become aware of the need for teamwork that must take place in schools and the importance of being up to date in terms of training in inclusive education and attention to diversity.
Key words
Inclusive education, Montessori, diversity, flexibility, individualityTutora: Itxaso Tellado Ruiz de Gaun
El Proceso de familiarización: Propuesta de un programa integral de familiarización en primera infancia
Curs 2022-2023El proceso que los niños y niñas en Primera Infancia viven en compañía de sus familias o referentes afectivos y los docentes implicados, al ingresar al sistema educativo o pasar de un nivel a otro, es conocido comúnmente como adaptación escolar. En la presente investigación se prefiere utilizar el término procesos de familiarización sugerido por diferentes autores, en el cual los actores educativos inician una historia común y establecen vínculos y relaciones, mientras hacen cotidiano el ambiente desconocido. A su vez, se diseña una propuesta de Programa de Familiarización Integral dirigido a apoyar a los centros educativos de Primera Infancia, mediante la aplicación de diferentes estrategias y recursos orientados a acompañar a los niños y niñas, sus familias o referentes afectivos, docentes y profesionales, y así poder contribuir a facilitar el proceso de familiarización para todos, concientizar sobre la importancia de preparar y planear con anticipación estos procesos a través de un programa de familiarización, donde se establezcan lineamientos claros del rol que desarrolla cada uno, en un período de tres a cuatro semanas y con acciones previas, durante y al finalizar el proceso. Para la presente investigación fue importante considerar el rol del adulto, así como la relación familia-escuela como factores determinantes en el proceso de familiarización de los niños y niñas en Primera Infancia. El Programa de Familiarización diseñado, se presentó y contrastó con las experiencias de las prácticas educativas que realiza el equipo institucional de L´Escoleta de la Vila. Los resultados obtenidos ratifican la importancia de que los centros educativos de Primera Infancia puedan contar con un instrumento guía que estructure el periodo de familiarización y facilite el proceso de todos los actores educativos en beneficio de los niños o niñas, sus familias o referentes afectivos y los docentes o guías como de las escuelas o colegios que integran el nivel de Primera Infancia.
Palabras clave: Primera Infancia; proceso de familiarización; programa de familiarización; rol del adulto; relación familia-escuela.In Early Childhood, school adaptation is commonly known as the processes that children, accompanied by their families or caregivers, and teachers experience when entering the educational system or moving from one school cycle to another. In the current investigation, the term familiarization process is preferred, as has been suggested by many authors, to refer to the process in which teachers, families and children begin to establish a relationship, while making the unknown classroom environment a routine place to go. Furthermore, a proposal of a Familiarization Program is designed to support Early Childhood educational centers, through the application of different strategies and resources aimed at accompanying children, their families or caregivers, and their teachers. Moreover, this Program aims to raise awareness about the importance of preparing and planning the familiarization process in advance, as well as to ease the process for everyone involved. Clear guidelines are established for the role that each individual develops before and during the familiarization process of approximately three to four weeks, and at the end of this process. Moreover, it is important to consider the role of the adult, as well as the family-school relationship, as factors that influence the familiarization processes of children in Early Childhood. Finally, the Familiarization Program is presented and contrasted with the experiences of the educational practices carried out by the institutional team of L'escoleta de la Vila. As a result, the data obtained in this investigation confirms the importance that Early Childhood centers plan and structure the familiarization process in a program that facilitates the process for all those involved to benefit the children, their families or caregivers, teachers, or guides, as well as schools that offer Early Childhood education.
Keywords: Early Childhood; familiarization process; familiarization program; role of the adult; family-school relationship.Tutora: María Gloria Olmos Martíne
Understanding the effect of ivermectin in non-severe COVID-19 patients through transcriptomics analyses
Curs 2022-2023Abstract
Motivation: Ivermectin inhibits SARS-CoV-2 replication in vitro at concentrations 35 times higher than approved clinical dosages for humans. This finding prompted numerous randomized clinical trials to assess its effectiveness. In a clinical trial conducted on non-severe COVID-19 patients to assess the efficacy of ivermectin reducing the transmission of SARS-CoV-2 trial, the ivermectin-treated group exhibited 30% less cough and 50% less anosmia/hyposmia, as well as trends indicating lower viral loads and IgG titers compared to the placebo group. The present study was conducted within the framework of this clinical trial to identify the immunomodulatory mechanisms of early ivermectin treatment during COVID-19, and to elucidate the molecular pathways activated during initial SARS-CoV-2 infection as well as their implications for the immune response to COVID-19.
Methods: In the clinical trial, 24 COVID-19 patients were randomly assigned in a 1:1 ratio to ivermectin (400 μg/kg) single oral dose or placebo. Peripheral blood was collected from these patients on days 1 (< 72 hours after symptoms onset and first day of treatment), 4 and 7 in PAXGene tubes and RNA extracted for RNA-Seq analyses. Differential Gene Expression (DGE) analysis was performed using DESeq followed by functional analysis using Gene Ontology (GO) framework. In addition, camera method was applied as it adjusts for inter-gene correlation, preventing the overestimation of variability and enabling accurate control of False Discovery Rate (FDR). In this approach, DGE was not performed, and Blood Transcriptional Modules (BTMs) were used for the direct assessment of differences in immune-related gene sets.
Results: On study day 1, all patients showed a notable upregulation of genes associated with viral response, some of them previously reported in COVID-19 studies, as well as genes associated with inflammation, innate response, and induction of apoptosis. As the disease progressed, the response became more adaptive. Ivermectin reduced inflammation on day 4. The ivermectin-treated group showed a rather adaptive response, mainly characterized by an upregulation of B and plasma cells-related BTMs on day 4, and an upregulation of many cell cycle-related BTMs, probably of T-cells, on day 7. The placebo group showed a rather innate response, mainly characterized by an upregulation of monocytes, neutrophiles and dendritic cell-related BTMs on day 4, and an upregulation of erythrocyte and leukocyte-related BTMs on day 7.
Conclusions: Ivermectin may reduce inflammation and produce a switch to an adaptive immune response, but no clear effect on COVID-19 responses was observed. Current evidence does not strongly support the use of ivermectin for COVID-19 treatment or prevention, but an immunomodulatory effect of ivermectin cannot be discarded.
Availability: Code is available at https://github.com/celiatorresvilanova/TFM
Contact: [email protected]
Supplementary information: Supplementary data encompass the analysis of the duplicates, which is available at the end of this thesis in the ‘Supplementary material’ and a table of differentially expressed genes (DEGs) related to the immune response in the disease progression (Supplementary file 1) available at https://github.com/celiatorresvilanova/TFMTutor: Josep Maria Serra
Analysis of cohesion and perceived behavior in professional handball players
El objetivo del presente estudio fue analizar la correlación entre las conductas del liderazgo percibido del Modelo Multidimensional de Liderazgo (MML) y las categorías de cohesión del Modelo de Cohesión de Carron en jugadores profesionales de balonmano. La muestra estuvo compuesta por un total de 112 jugadores a los cuales se les administró los cuestionarios Leadership Scale for Sport (LSS2) y el Group Environment Questionaaire (GEQ). Los resultados obtenidos (r = de 0.307 - 0.634) muestran una asociación entre la variable de cohesión (ATG-T) y las conductas percibidas del (MML). Se observa una tendencia de cohesión hacia la tarea por parte de los jugadores. La conducta autocrática supera la democrática y la de entrenamiento e instrucción obtiene los valores más elevados. Concluimos que la cohesión hacia la tarea es la predominante en jugadores de alto rendimiento y que la alta exigencia de la categoría demanda de diferentes conductas del entrenador.The objective of this study was to analyse the correlation between perceived leadership behaviours of the Multidimensional Leadership Model (MML) and the cohesion categories of the Carron Cohesion Model in professional handball players. The sample was composed by 112 players who answered the Leadership Scale for Sport (LSS2) and the Group Environment Questionnaire (GEQ) questionnaires. The results obtained (r = from 0.307 to 0.634) show an association between the cohesion variable (ATG-T) and the perceived behaviours of the (MML). A cohesion tendency towards the task by the players is observed. Autocratic behaviour exceeds democratic behaviour and training and instruction behaviours obtain the highest values. We conclude that cohesion towards the task is predominant in high performance players and that the high demand of the category demands different behaviours from the coach
Decàleg per a una intel·ligència artificial (IA) segura en l'entorn d'aprenentatge universitari
Unveiling distinct features of long-term benefit in metastatic NSCLC patients undergoing immune checkpoint blockade
Curs 2022-2023Introduction: Immunotherapy is firmly established as a treatment regimen in various solid
tumors, driven by its exceptional benefits observed in a select group of patients. Despite
widespread use of immune checkpoint blockade (ICB) across diverse solid tumors, the quest
for a clinically informative biomarker for long-term benefit remains unmet.
Methods: A total of 49 metastatic NSCLC patients treated with ICB were included. Long-term
(LTR) and Short-term responders (STR) were defined as those with a response to ICB lasting
more than 24 months or less than 6 months, respectively. Longitudinal blood specimens were
collected before treatment initiation and early-on treatment (before cycle 2 – at 3rd week).
Plasma ctDNA NGS panel and serum proteomics were performed. Standard diagnostic
workup included PD-L1 immunohistochemistry and NGS in tumor tissue. Tumor tissue
RNAseq panel focused on immune related genes was performed in a subset of patients.
Results: Our analysis revealed specific characteristics of long-term patients compared with
short term benefit, namely higher PD-L1 in tumor cells (p=0.005) and higher incidence of irAEs
(p=0.001). Genomic features that associated with lack of benefit to ICB included cooccurrence
of mutations in KRAS/STK11, KRAS/KEAP1 and TP53/KMT2D (p<0.05). At a
serum proteomic level, LTR patients exhibited higher abundance of proteins related with
apoptosis (CASP8, PRKRA), chemotaxis, immune proteosome, processing of MHC class I
(S100A4, PSMD9, RNF41) and immunehomeostasis (HAVCR1, ARG1) (p<0.05 for all
proteins). In line with peripheral immunological features, transcriptional analysis of tumor
samples showed that LTR patients displayed higher levels of genes linked with T cell
recruitment/trafficking (CXCL11) and T cell effector functions (GMZB) within the tumor
microenvironment (p<0.05). Finally, a longitudinal analysis identified a set of proteins that
presented opposite dynamics in LTR compared to STR, making them interesting candidates
for treatment efficacy evaluation.
Conclusions: Our comprehensive analysis of metastatic NSCLC patients treated with ICB
has unveiled distinct clinicopathological and immunological features associated with long-term
benefit, highlighting the presence of a pre-existing antitumor immunity as a stronger predictor
of long-term benefit. These findings offer insights into potential biomarkers and therapeutic
strategies for enhancing ICB outcomes in metastatic NSCLC.
Keywords: Lung neoplasms; Immunotherapy; Long-term responders; Serum proteomics;
blood-based biomarkers.Academic tutor: Josep M. Serra
Dispositius mecànics que utilitzen les infermeres pel control de l'hemorràgia exterioritzada a nivell prehospitalari: Revisió bibliogràfica sistematitzada
Curs 2022-2023Introducció: L’hemorràgia massiva externa localitzada a les extremitats, produïda per un traumatisme, ocasiona la mort de la persona en pocs minuts. Així doncs, és essencial una atenció infermera immediata pel control del sagnat massiu mitjançant l’ús del torniquet.
Objectiu: Descriure els sistemes de control del sagnat exterioritzat en extremitats disponibles pel seu ús a nivell extrahospitalari i valorar-ne l’efectivitat, identificar els mecanismes lesionals que provoquen l’hemorràgia i avaluar la relació temps-supervivència.
Metodologia: Es realitza la pregunta d’investigació en format PICO i la cerca bibliogràfica d’articles publicats des del gener del 2017 fins a finals de gener del 2023 a les bases de dades: PubMed, Cinahl, Cuidatge, Scopus, Web of Science, SCIELO i Biblioteca virtual en Salut.
Resultats: Per dur a terme aquesta revisió bibliogràfica s’han seleccionat un total de divuit articles utilitzant el diagrama de flux de la guia PRISMA amb posterior avaluació de qualitat dels articles CASP i STROBE.
Conclusions: Existeixen tres mètodes per controlar l’hemorràgia a nivell extrahospitalari: compressió directa, agents homeostàtics i torniquets. L’ús precoç del torniquet està associat a un augment de la supervivència del pacient, menors complicacions secundàries i un menor nombre transfusions sanguínies.
Paraules clau: Torniquete; Exanguinación; Servicios prehospitalariosIntroduction: External massive hemorrhage located in limbs produced by a trauma, produces death to the person in few minutes. This, it is essential an immediate medical assistance to control the massive bleeding by using a tourniquet.
Objective: To describe the external massive limbs hemorrhage control systems in a non-hospital context and evaluate its effectivity. Also identify the injury mechanisms that cause the hemorrhage and evaluate the relation time-survival.
Methodology: The question of investigation is done in PICO format and bibliographic search of scientific papers published from January 2017 to January 2023 found in: PubMed, Cinahl, Cuidatge, Scopus, Web of Science, SCIELO i Biblioteca virtual en Salut.
Results: For this bibliographic revision to be done a total of eighteen papers have been selected using the flux diagram from PRISMA guide, with the posterior evaluation of the quality of the papers on CASP and STROBE.
Conclusions: Exist three methods to control non-hospital hemorrhage: direct compression, hemostatic agents and tourniquet. The premature use of the tourniquet is directly associated to an increase of the patient survival, less secondary complications and smaller amount of blood transfusions.
Keywords: Tourniquets; Exsanguination; Emergency medical service
Impacte d'un checklist quirúrgic modificat sobre el control de les infeccions de la localitat quirúrgica
Curs 2022-2023Introducció: Els professionals d’infermeria, tenen la responsabilitat de supervisar i comprovar periòdicament els diversos processos administratius i operatius de l’aplicació rigorosa de les normes i els principis d’asèpsia i antisèpsia quirúrgica. Per això, és de vital importància l’aplicació d’aquestes eines amb la finalitat d’evitar que les infeccions de localitat quirúrgica (ILQ) relacionades amb l’assistència sanitària es produeixin. Actualment, el cheklist quirúrgic és un dels instruments fonamentals que s’utilitzen per prevenir aquestes infeccions. L’ús correcte del checklist quirúrgic reforça la pràctica segura i alhora garanteix la seguretat dels pacients a quiròfan.
Objectiu: Avaluar l’impacte d’un checklist quirúrgic modificat tenint en compte ítems de baix risc marcats pel projecte PrevinQ-cat l’any 2023 i altres estudis relacionats amb la prevenció d’ILQ sobre la millora de l’acompliment del rol infermer, el control i detecció dels riscos en l’àrea quirúrgica i la taxa de les ILQ i la seva severitat, respecte al checklist habitual.
Metodologia: Es portarà a terme un assaig clínic aleatoritzat en dos grups: Grup Control (on es portarà a terme el cheecklist quirúrgic que s’utilitza habitualment) i Grup Intervenció (on es portarà a terme el cheecklist modificat segons els ítems del projecte PrevinQ-cat i altres estudis relacionats amb la prevenció d’ILQ) a l’àrea quirúrgica de l’Hospital Universitari de Vic, l’any 2024. La població d’estudi seran els pacients intervinguts de manera programada vinculats amb el checklist i les infermeres quirúrgiques que el complimenten. Variables d’estudi relacionades amb els pacients: Sociodemogràfiques, clíniques i percentatge d’infeccions. Variables d’estudi relacionades amb les infermeres: Variables sociodemogràfiques, L’acompliment del rol (indicadors NOC) i control i detecció dels riscos (indicadors NOC). La recollida de dades tindrà lloc a l’inici de l’estudi i al cap de 10 mesos.
Limitacions: Dificultat per trobar pacients i infermeres que puguin complir els criteris d'inclusió i exclusió i estiguin disposats a formar part de l'estudi, complint els requisits demanats. Falta de compromís per part de les infermeres. El Grup Control ho relacioni de forma negativa, sabent que hi ha un grup beneficiat per rebre una intervenció addicional.
Paraules claus: Checklist; Infeccions de localitat quirúrgica; Infeccions nosocomial; Infermeria; Llista de verificació quirúrgica; PrevencióIntroduction: Nursing professionals have the responsibility to supervise and periodically check the various administrative and operational processes of the rigorous application of the rules and principles of asepsis and surgical antisepsis. For this reason, the application of these tools is vitally important in order to prevent surgical site infections (SIIs) related to health care from occurring. Currently, the surgical checklist is one of the fundamental instruments used to prevent these infections. The correct use of the surgical checklist reinforces safe practice and at the same time guarantees the safety of patients in the operating room.
Objective: To evaluate the impact of a modified surgical checklist taking into account low-risk items marked by the PrevinQ-cat project in 2023 and other studies related to the prevention of surgical site infections, on the improvement of role performance nurse, the control and detection of risks in the surgical area and the rate of these infections and their severity, with respect to the usual checklist.
Methodology: A randomized clinical trial will be carried out in two groups: Control Group (where the commonly used surgical checklist will be carried out) and Intervention Group (where the modified checklist will be carried out according to the items of the PrevinQ-cat project and other studies related to the prevention of surgical site infections ) in the surgical area of the Hospital Universitari de Vic, in the year 2024. The study population will be the patients intervened in a programmed manner linked to the checklist and the surgical nurses who they comply Study variables related to the patients: Sociodemographics, clinics and percentage of infections. Study variables related to nurses: Socio-demographic variables, Role performance (NOC indicators) and risk control and detection (NOC indicators). Data collection will take place at the beginning of the study and after 10 months.
Limitations: Difficulty in finding patients and nurses who can meet the inclusion and exclusion criteria and are willing to be part of the study, fulfilling the requested requirements. Lack of commitment on the part of nurses. The Control Group relates it negatively, knowing that there is a benefited group to receive an additional intervention.
Keywords: Checklist; Surgical site infections; Nosocomial infections; Nursing; Surgical checklist; Preventio