Bezmialem Vakıf Üniversitesi Kurumsal Akademik Arşiv
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Stabil Mi Değil Mi? İdrar Örneklerinin Stabilitesinin Strip Testleriyle Değerlendirilmesi
No full textEfficacy of fetal left ventricular modified myocardial performance index in predicting adverse perinatal outcomes in intrahepatic cholestasis of pregnancy
No full textObjective: This study aimed to evaluate the effectiveness of fetal left ventricular modified myocardial performance index in predicting adverse perinatal outcomes for intrahepatic cholestasis of pregnancy.
Methods: A cross-sectional study was conducted, including 51 women with intrahepatic cholestasis of pregnancy and 80 healthy controls. Using Doppler ultrasonography, E-wave, A-wave, isovolumetric contraction time, isovolumetric relaxation time, and ejection time were recorded and the left ventricular modified myocardial performance index was measured.
Results: Findings showed that the mean left ventricular modified myocardial performance index, isovolumetric contraction time, and isovolumetric relaxation time values were statistically significantly higher while the ejection time and E/A ratios were statistically significantly lower in the intrahepatic cholestasis of pregnancy group than the control group. In the intrahepatic cholestasis of pregnancy group, a statistically significant positive correlation was found between left ventricular modified myocardial performance index and adverse perinatal outcomes in the intrahepatic cholestasis of pregnancy group (r=0.478, p<0.001), while a statistically significant negative correlation was found between the E/A ratio and adverse perinatal outcomes (r=-0.701, p<0.001).
Conclusions: For intrahepatic cholestasis of pregnancy cases, high fetal left ventricular modified myocardial performance index values were an indicator of ventricular dysfunction, and this correlated with negative perinatal outcomes
The Evaluation of the Effect of the Pterygo-maxillary Junction Structure on Surgically Assisted Maxillary Expansion by Finite Element Analysis
No full textSulodexide protected the heart against ischemia/reperfusion injury by reducing oxidative stress, inflammation, and apoptosis in the isolated rat heart
No full text
Laringomalazi tanımı, tanı ve tedavisi
No full textLaringomalazi yenidoğan ve infantlarda inspiratuar stridor en sık nedenidir, bu çocukların %10\"unda cerrahi girişim gerektiren ciddi semptomlar mevcuttur. Laringomalazide supraglottik larinksin kollabe olması sonucunda inspiratuar stridor görülür. Tanıda öncelikle fleksibl fiberoptik laringoskop ile değerlendirilme önerilmektedir. Senkronize havayolu lezyonlarının tespiti için bronkoskopi de yapılmalıdır. Laringomalazi şiddeti; hafif, orta ve ağır olarak değerlendirilir. Hafif, orta ve şiddetli olgular için ise asit süpresyon tedavisi, yutma terapisi ve yutmanın değerlendirilmesi tavsiye edilmiş olup; şiddetli laringomalazide laringoskopi/bronkoskopi sonrasında supraglottoplasti tavsiye edilmiştir. Supraglottoplasti laringomalazili çocukların çoğunluğunda başarı ile sonuçlanır. Ancak eşzamanlı havayolu patolojileri ve komorbid hastalıkların varlığı olumsuz sonuçlara neden olabilir ve trakeostomi gerektirebilir.Laryngomalacia is the most common cause of inspiratory stridor in neonates and infants, with 10% of these children having severe symptoms requiring surgical intervention. Inspiratory stridor is seen as a result of collapse of the supraglottic larynx in laryngomalacia. In the diagnosis, evaluation with a flexible fiberoptic laryngoscope is recommended. Bronchoscopy should also be performed to detect synchronous airway pathologies. Laryngomalacia severity; rated as mild, moderate and severe. Acid suppression therapy, swallowing therapy and evaluation of swallowing were recommended for mild, moderate and severe cases; Supraglottoplasty is successful in the majority of children with laryngomalacia. However, the presence of syncronous airway pathologies and comorbid conditions may result worse outcomes and may require tracheostomy
