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How to ask the obvious
No full textEnglish can express the basic meaning of a yes/no question in several ways, for example with or without sentential negation, and with or without subject auxiliary inversion. In this paper, we discuss how the presence of contextual clue with respect to one or the other answer to a yes/no question determines which formal variants of the question are felicitous. We then derive these syntax-pragmatics interactions from Heim’s principle of Maximize Presupposition, Stalnaker’s Bridge Principle and Grice’s Maxim of Manner, each formulated in a particular way, together with the assumption that the lexicon of English contains a silent evidential marker which exhibits familiar syntactic and semantic properties
Don\u27t Dream Dreams
No full textSpletni katalog razstave Ne sanjajte sanj: Izbor iz zbirke Telekom in novi deli, 3. maj - 17. september 2023, Moderna galerija v Ljubljani. Odprtje razstave: torek, 23. maj 2023 ob 20. uri. V umetninah, ki so arhivi elementov, je najpomembnejše urejanje množice sestavin, ne pa njeno odpravljanje, na primer tako, da bi se skupek elementov nadomestil s splošnim, s pravili, po katerih nastajajo oz. ki predstavljajo njihovo enovito, globljo poanto. Od soočanja z zgodovino umetnosti, prek kozmologij, edukacijskih situacij, urbanizma, do zbirk risb in t.i. psiholoških gledališč ter antropomorfnih skulptur – v petih dvoranah MG+ bo na ogled več kot 40 del in projektov 25 umetnic in umetnikov, ki prihajajo iz vzhodne in jugovzhodne Evrope. V okviru razstave bosta predstavljeni tudi dve novi naročeni deli. Saša Auerbah, Jane Čalovski, Danica Dakić, Aleksandra Domanović, Kyriaki Goni, Petrit Halilaj, Pravdoljub Ivanov, Hortensia Mi Kafchin, Ali Kazma, Luka Kedžo, Eva Kot\u27átková, Marija Kulikovska, Marek Kvetan, Piotr Łakomy, Ciprian Mureşan, Paul Neagu, Paulina Ołowska, Roman Ondák, Agnieszka Polska, Stepan Rjabčenko, Slavs and Tatars, Marko Tadić, Iza Tarasewicz, Krasimir Terziev, Martina Vačeva. Novi produkciji: Maja Babič Košir: Brat, povej mi, Lana Čmajčanin: Ne sanjajte sanj. Kustosa razstave: Nathalie Hoyos, Rainald Schumacher. Koordinacija: Robert Simonišek, Jure Vuga. Konservatorsko-restavratorska priprava gradiva, koordinacija: Simona Škorja. Besedila: Aleš Vaupotič, Nathalie Hoyos, Igor Španjol. Grafično oblikovanje: Eduard Čehovin. Odnosi z javnostmi: Mateja Lavrič. Tehnični koordinator: Tomaž Kučer. Spletišče: Aleš Vaupotič, Jaka Železnikar, Vikida. Tehnična ekipa: Boris Fister, Armin Salihović, Duško Škrbin. Producenta: Moderna galerija, Deutsche Telekom.Online interactive catalogue for the exhibition Don\u27t Dream Dreams: A Selection from the Art Collection Telekom and Two Commissioned Works, Moderna galerija, MG+
23 May – 30 July 2023. Exhibition opening: Tuesday 23 May 2023 at 8 p.m. In works of art, which are archives of elements, the most important thing is to arrange the multitude of components, rather than their elimination, for example, by replacing the set of elements with a generalization, with the rules according to which they are created, or which represent their unified, deeper point. From dealing with the history of art, through cosmologies, educational situations, urban planning, to collections of drawings, so-called psychological theaters and anthropomorphic sculptures - more than 40 works and projects by 25 artists from Eastern and Southeastern Europe will be on display in the five halls of MG+. Two new commissioned works will also be presented as part of the exhibition. Sasha Auerbakh, Yane Calovski, Danica Dakić, Aleksandra Domanović, Kyriaki Goni, Petrit Halilaj, Pravdoliub Ivanov, Hortensia Mi Kafchin, Ali Kazma, Luka Kedžo, Eva Kot\u27átková, Maria Kulikovska, Marek Kvetan, Piotr Łakomy, Ciprian Mureşan, Paul Neagu, Paulina Ołowska, Roman Ondak, Agnieszka Polska, Stepan Ryabchenko, Slavs and Tatars, Marko Tadić, Iza Tarasewicz, Krassimir Terziev, Martina Vacheva. Commissioned works: Maja Babič Košir: Tell Me Brother, Lana Čmajčanin: Don\u27t Dream Dreams. Exhibition curators: Nathalie Hoyos, Rainald Schumacher. Coordination: Robert Simonišek, Jure Vuga. Conservation, coordination: Simona Škorja. Texts: Aleš Vaupotič, Nathalie Hoyos, Igor Španjol. Graphic design: Eduard Čehovin. Public relations: Mateja Lavrič. Technical coordinator: Tomaž Kučer. Website: Aleš Vaupotič, Jaka Železnikar, Vikida. Technical crew: Boris Fister, Armin Salihović, Duško Škrbin. Production: The Museum of Modern Art, Ljubljana, Deutsche Teleko
Modeliranje vloge topil za eksperimentalne raziskave zvijanja proteinov
Get PDFThe Zimm-Bragg (ZB) model serves as a fundamental framework for elucidating conformational transitions in biopolymers, offering simplicity and efficacy in processing experimental data. This study provides a comprehensive review of the Zimm-Bragg model and its Hamiltonian formulation, with particular emphasis on incorporating water interactions and chain size effects into the computational framework. We propose a modified ZB model that accounts for water-polypeptide interactions, demonstrating its ability to describe phenomena such as cold denaturation and helix-coil transitions. In the realm of NanoBioTechnologies, the manipulation of short polypeptide chains is commonplace. Experimental investigation of these chains in vitro often relies on techniques like Circular Dichroism (CD) and timeresolved infrared spectroscopy. Determining interaction parameters necessitates processing the temperature dependence of the normalized degree of helicity through model fitting. Leveraging recent advancements in the Hamiltonian formulation of the Zimm and Bragg model, we explicitly incorporate chain length and solvent effects into the theoretical description. The resulting expression for helicity degree adeptly fits experimental data, yielding hydrogen bonding energies and nucleation parameter values consistent with field standards. Differential Scanning Calorimetry (DSC) stands as a potent tool for measuring the specific heat profile of materials, including proteins. However, relating the measured profile to microscopic properties requires a suitable model for fitting. We propose a novel algorithm for processing DSC experimental data based on the ZB theory of protein folding in water. This approach complements the classical two-state paradigm and provides insights into protein-water and intraprotein hydrogen bonding energies. An analytical expression for heat capacity, considering water interaction, is derived and successfully applied to fit numerous DSC experimental datasets reported in the literature. Additionally, we compare this approach with the classical two-state model, demonstrating its efficacy in fitting DSC data. Furthermore, we have developed and launched a free online tool for processing CD and DSC experimental data related to protein folding, aiming to support scientific research
VANTAGGI E DIFFICOLTÀ NELL’EDUCAZIONE MULTILINGUE
No full textInteraktivna delavnica o izzivih vzgoje v večjezičnem okoljuSrečanje v obliki interaktivne delavnice je bilo namenjeno staršem otrok, ki obiskujejo vrtce s slovenskim učnim jezikom v Gorici. Pogovarjali so se o izzivih vzgoje v večjezičnem okolju. Prof. dr.Penka Stateva z Univerze v Novi Gorici je spregovorila o najnovejših znanstvenih raziskavah na področju večjezičnosti, ki so bili izvedeni na UNG
