University of Malaga

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    Inequalities on tent spaces and closed range integration operators on spaces of average radial integrability

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    We deal with a reverse Carleson measure inequality for the tent spaces of analytic functions in the unit disc D of the complex plane. The tent spaces of measurable functions were introduced by Coifman, Meyer and Stein. Let 1 ≤ p, q < ∞ and consider the measurable set G ⊆ D. We prove a necessary and sufficient condition on G in order to exist a constant K > 0 such that T β (ξ )∩G | f (z)| p dm(z) 1 − |z| q/p |dξ | ≥ K T 1/2(ξ ) | f (z)| p dm(z) 1 − |z| q/p |dξ |, for any analytic function f in D with the property, the right term of the inequality above is finite. Here T stands for the unit circle, dm(z) is the area Lebesgue measure in D and β(ξ ) is the cone-like region β(ξ ) = {z ∈ D |z| < β} ∪ |z|<β [z, ξ ), β ∈ (0, 1), with vertex at ξ ∈ T. This work extends the study of D. Luecking on Bergman spaces to the analytic tent spaces. We apply this result in order to characterize the closed range property of the integration operator Tg( f )(z) = z 0 f (w)g (w) dw, z ∈ D, when acting on the average radial integrability spaces. The Hardy and the Bergman spaces form part of this family. The function g is a fixed analytic function in the unit disc. The operator Tg is known as Pommerenke operator. Moreover, for the first time, we provide examples of symbols g that introduce or not a closed range operator Tg in these spaces.Funding for open access charge: Universidad de Málaga / CBU

    Barreras a la enseñanza en la era digital. Reflexiones sobre la historia de una maestra

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    Este artículo tiene como propósito estudiar el escenario profesional docente para identificar las estructuras y dispositivos que nos llevan al profesorado a una experiencia compartida de malestares y de dificultad para atender a todas nuestras obligaciones profesionales. Realizamos este trabajo a través del análisis de la historia de Laura, maestra de Educación Primaria. En esta investigación narrativa observamos que el escenario profesional docente deposita toda la responsabilidad de construcción de una escuela inclusiva en la actividad individual de cada docente, que se termina viendo forzado a recurrir a herramientas digitales privadas y estrategias del tecnosolucionismo. Para confrontar este modelo individualista proponemos el concepto de barreras a la enseñanza, como una forma de colectivizar los obstáculos de la práctica profesional en las aulas

    Some structure theorems

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    El objetivo de este trabajo es probar dos importantes teoremas de estructura de anillos: el Teorema de Artin-Wedderburn y el Teorema de Densidad de Jacobson. En el primer capítulo sentaremos las bases sobre las que trabajaremos. En este, estudiaremos los conceptos de anillo y módulo y demostraremos resultados que serán de gran relevancia en los siguientes capítulos. El segundo capítulo es el destinado a probar el Teorema de Artin-Wedderburn, que clasifica los anillos semisimples. Comenzaremos el capítulo trabajando sobre los anillos simples y semisimples. Tras ello, introduciremos la condición de cadena descendente y la condición de cadena ascendente y hablaremos de módulos y anillos artinianos y noetherianos. También veremos las nociones de anillos primos y semiprimos. Una vez realizado este desarrollo teórico, procederemos a demostrar el Teorema de Artin-Wedderburn. Primero veremos su versi´on para Anillos Simples, que utilizaremos para demostrar el Teorema de Artin-Wedderburn general. El tercer capítulo trata sobre Teorema de Densidad de Jacobson, que clasifica los anillos primitivos. Primero veremos la noción de anillos primitivos por la derecha y por la izquierda. En la segunda subsección demostraremos el Teorema de Densidad para M´odulos Semisimples y, haciendo uso de dicho resultado, probaremos el Teorema de Densidad de Jacobson para anillos primitivos por la derecha. Trabajando con módulos a izquierda en vez de módulos a derecha de obtiene el Teorema de Densidad de Jacobson para anillos primitivos por la izquierda

    Anti‑nervous necrosis virus activity of the growth hormone releasing peptide‑6, GHRP‑6

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    Growth hormone-releasing peptide 6 (GHRP-6), is a six-amino acid synthetic peptide that acts as a ghrelin analog and has shown growth-promoting and immunomodulatory activities in several fish species. This study evaluates the effects of GHRP-6 against the infection with the nervous necrosis virus (NNV), an important pathogen affecting the central nervous system of a wide range of fish species, including European seabass (Dicentrarchus labrax). For the in vitro evaluation, E11 cells were treated with GHRP-6 before and/or during viral infection, resulting in higher cellular survival rates, lower viral genome replication, and lower production of infective viral particles compared with control cells. These results indicate that GHRP-6 protects E11 cells from the viral infection. In order to conduct the in vivo evaluation, European seabass specimens were intraperitoneally injected with GHRP-6, resulting in the significant upregulation of several immune genes, such as TNF-A, RTP3, and IgM, in head kidney and intestine. Furthermore, NNV replication was lower in the brain from GHRP-6 injected fish than in controls, and the brain antiviral immune response was clearly modulated in treated fish. These results support the potential of GHRP-6 as an antiviral compound that could contribute to prevent viral diseases in fish farms, a priority for the aquaculture IndustryFunding for open access publishing: Universidad de Málaga/CBUA. This study has been funded by the UMA20-FEDERJA-020 project (Regional Government). Daniel Álvarez-Torres has been granted the project PTA2020-018984-I and R. Martinez was granted with a Plan Propio fellowship from University of Malaga

    Copper in colorectal cancer patients: a systematic review and meta-analysis.

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    Several clinical studies have evaluated the relationship between copper on colorectal cancer (CRC), but the results are contradictory. This study aimed to conduct a systematic review and meta-analysis to investigate copper measured in two biological matrices (serum/plasma/blood and tissue) and dietary intake in CRC patients compared to healthy controls. We conducted a comprehensive and systematic search in PubMed, Scopus, Embase, and Web of Science. We included studies that reported copper levels in serum/plasma/blood, tissue, or from the diet, with an observational study design (cohort and case–control studies). Study quality was assessed with the Newcastle–Ottawa scale and potential causes of heterogeneity were evaluated. Standardized mean differences (SMD) with 95% confidence interval (CI) were pooled using random-effect models. Overall pooled odds ratio and 95% CI for the risk of CRC were calculated. Twenty-six studies (23 case–control and 3 cohort studies) with a total of 227 354 participants were included. Most of the studies presented low (50%) or moderate quality (42.3%). No differences in serum/plasma/blood copper levels (SMD = 0.23; 95% CI: −0.23, 0.70; I2 = 97.3%, 19 studies), tissue copper levels (SMD = −1.69; 95% CI: −3.41, 0.03; I2 = 85.6%, 2 studies), or copper/zinc ratio (SMD = 1.19; 95% CI: 0.54, 1.84; I2 = 95.3%, 6 studies) were found between CRC patients and healthy controls. Regarding dietary copper, CRC patients had a lower intake (SMD = −0.27; 95% CI: −0.51, −0.03; I2 = 0.0%, 2 studies). No differences were found in copper levels between CRC patients and healthy controls. However, evidence shows mostly low or moderate quality, and results were heterogeneous. More prospective studies with an adequate methodological approach are needed

    Acciones colectivas indemnizatorias en casos de contaminación.

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    SUMARY: The Spanish Civil Procedure Act recognises the standing of associations for the collective defence of interests in areas such as consumer protection, equality of treatment, sexual identity and the labour rights of certain groups. However, it expressly omits the possibility of bringing collective actions in respect of personal injury arising from environmental pollution. This legislative gap compels affected individuals to resort to individual proceedings which, given the large-scale, diffuse and slow-to-manifest nature of such harm, complicates the identification of liable parties, increases the evidentiary burden and generates disproportionate procedural costs, thereby hindering effective access to justice and infringing the fundamental right to effective judicial protection enshrined in Article 24 of the Spanish Constitution, as well as the human right to a healthy environment. Law 26/2007 on Environmental Liability, which adopts a predominantly administrative approach, expressly excludes personal injury from its scope of application, referring victims to ordinary civil jurisdiction. This results in fragmented protection and highlights the need to establish specific procedural mechanisms for the collective defence of such interests. In this context, it is proposed to introduce a new Article 11 quinquies into the Civil Procedure Act, recognising the active standing of duly constituted associations and the Public Prosecutor’s Office to defend in court the rights and interests of persons affected by personal injury resulting from pollution, especially where diffuse or individually indeterminate interests are at stake, subject to the registration and statutory requirements of the entities concerned. Such a reform would overcome the current obstacles, optimise resources and ensure effective judicial protection appropriate to the nature of environmental harm.RESUMEN: La Ley de Enjuiciamiento Civil reconoce la legitimación de asociaciones para la defensa colectiva de intereses en ámbitos como el consumo, la igualdad de trato, la identidad sexual y los derechos laborales de determinados colectivos, pero omite expresamente la posibilidad de ejercitar acciones colectivas en materia de daños personales derivados de la contaminación ambiental. Esta laguna normativa obliga a los afectados a acudir a la vía individual, lo que, dada la naturaleza masiva, difusa y de lenta manifestación de estos daños, dificulta la identificación de responsables, incrementa la carga probatoria y genera costes procesales desproporcionados, obstaculizando el acceso efectivo a la justicia y vulnerando el derecho fundamental a la tutela judicial efectiva reconocido en el artículo 24 de la Constitución Española, así como el derecho humano a un medio ambiente saludable. La Ley 26/2007 de Responsabilidad Medioambiental, de marcado carácter administrativista, excluye expresamente los daños personales de su ámbito de aplicación, remitiendo a los perjudicados a la jurisdicción civil ordinaria, lo que fragmenta la protección y evidencia la necesidad de habilitar mecanismos procesales específicos para la defensa colectiva de estos intereses. En este contexto, se propone la incorporación de un nuevo artículo 11 quinquies en la LEC que reconozca la legitimación activa de asociaciones legalmente constituidas y del Ministerio Fiscal para la defensa en juicio de los derechos e intereses de las personas afectadas por daños personales derivados de la contaminación, especialmente cuando se trate de intereses difusos o de difícil determinación individual, exigiendo la inscripción registral y la previsión estatutaria de dichos fines en las entidades legitimadas. Esta reforma permitiría superar los obstáculos actuales, optimizando recursos y garantizando una protección judicial efectiva y adecuada a la naturaleza de los daños ambientales.El presente trabajo ha sido realizado en el seno del Proyecto SEJ-163-G-FEDE

    Reseña de La crisis del capitalismo financiero, Martin Wolf, Ed. Deusto, 2023.

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    Reseña bibliográfica y comentarios de la obra

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    Advances in Indoor Semantic Mapping for Mobile Robotics

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    Para que los robots móviles operen de forma autónoma en entornos reales y complejos, es indispensable que sean capaces de interpretar información de alto nivel sobre su entorno. Este tipo de información va más allá de la meramente geométrica, permitiendo reconocer y categorizar elementos de la escena (como por ejemplo, objetos o lugares) y asociarlos con sus funcionalidades. Adquirir esta comprensión es crucial para permitirles interactuar y tomar decisiones de forma análoga a como lo hacemos los humanos. Dotar a los robots de esta capacidad interpretativa exige representaciones internas que integren tanto la geometría del entorno como su significado asociado. Esta tesis avanza en la creación de mapas semánticos, una representación interna que permite a los robots vincular información geométrica con conocimiento semántico de alto nivel. Estos mapas posibilitan que un robot asocie elementos del entorno con sus atributos, funcionalidades y relaciones, facilitando un razonamiento más avanzado. Para lograrlo, se abordan tres retos principales: (i) la categorización semántica de lugares mediante un mecanismo de atención activa que optimiza la observación del entorno; (ii) la reconstrucción estructural 3D en tiempo real basada en planos; y (iii) la creación de mapas semánticos orientados a objetos, proponiendo dos métodos que abordan algunas de las limitaciones presentes actualmente en la creación de mapas semánticos basados en instancias. Adicionalmente, se presenta y aborda por primera vez el problema de la localización visual con detectores heterogéneos. Se propone un método que explota información estructural derivada de los mapas semánticos para imponer restricciones de coplanaridad, guiando eficazmente el emparejamiento de características extraídas por detectores heterogéneos

    Pseudomonas syringae lipopolysaccharide synthesis gene wbpL displays heterogeneous expression within in vitro and in planta populations

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    PID2021-127245OB-I00 MCIN/AEI/10.13039/501100011033/Phenotypic heterogeneity usually refers to phenotypic variation not associated with genetic variation, nor induced by environmental stimuli. The phenotypic heterogeneity processes described for some complex bacterial traits are causing a shift in how bacterial phenotypes are studied, from traditional assessments by averaging populations to single-cell analysis focused on bacterial individual phenotypes and how these distribute within the population. The structure of the lipopolysaccharide (LPS) layer on the outer membrane in Gram-negative bacteria is often subjected to phenotypic variation, a process that is critical for virulence in animal pathogens. Here, we apply single-cell expression analyses to wbpL, a conserved Pseudomonas syringae glycosyltransferase-encoding gene essential for the synthesis of the O-antigen component of LPS. We show that expression of wbpL displays phenotypic heterogeneity in P. syringae pv. phaseolicola growing in rich medium and reaches bistable expression in minimal medium, where the population splits into WbpLON and WpbLOFF subpopulations. In planta, wbpL expression is also heterogeneous, displaying intermingled ON/OFF with comparable viability. Finally, we followed the expression of wbpL within the spatial context of apoplastic microcolonies, and not only detected heterogeneity within each microcolony, but also found that microcolonies displayed overall differences in fluorescence intensity that correlated with size, with smaller microcolonies displaying higher levels of wbpL expression.II Plan Propio de Investigación, Transferencia y Divulgación Científica UM

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