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El decreto-ley balear 1/2020 contra el turismo de excesos
El Decreto-ley balear 1/2020 contra el turismo de excesos tiene por objetivo transformar el modelo turístico que hoy en día se encuentra implantado en el archipiélago. Un modelo de turismo que el paso del tiempo ha demostrado redundar en problemas de orden público. Para ello, se ha aprobado una norma sobre comercio, turismo y espectáculos, pero cuyo fin último no es otro que proteger y salvaguardar el orden público.The Balearic Decree-Law 1/2020 against excess tourism aims to transform the tourism model that is currently implemented in the archipelago. A tourism model that causes public order problems. In order to avoid this kind of problems, a trade, tourism and entertainment regulation has been approved with the one and only purpose of protecting and safeguarding public order
Language and Cognitive Impairment
Embargado hasta 01/01/2100Mutations in the MED13L gene, which encodes a subunit of a transcriptional regulatory complex, result in a complex phenotype entailing physical and cognitive anomalies. Deep language impairment has been reported in affected individuals, mostly in patients with copy number variations. We report on a child with a nonsynonymous p.Cys63Arg change in MED13L (chr12:116675396A>G, GRCh37) who exhibits profound language impairment in the expressive domain, cognitive delay, behavioral disturbances, and an autism-like phenotype. Because of the brain areas in which MED13L is expressed and because of the functional links between MED13L and the products of selected candidate genes for cognitive disorders involving language deficits, the proband's linguistic phenotype may result from changes in a functional network important for language development and evolution
Subtitling documentaries: A learning tool for enhancing scientific translation skills
Embargado hasta 01/01/2100This paper examines the use of subtitles as a learning tool for developing skills required for scientific translation, in the framework of the course "Scientific and Technical Translation" included in the Translation and Interpreting Studies degree at the University of Cordoba. For that purpose, in the present study we aim to discuss and describe the benefits provided by this modality of audiovisual translation by presenting an overview of the previous studies focused on the effectiveness of subtitling in foreign language (FL) learning. However, we intend to go deeper and propose the integration of subtitling not only in translation studies curriculum, but more specifically, in a scientific translation course. Furthermore, the documentary genre is postulated as an optimal audiovisual media to be used for FL specialised language learning. The subtitling activity consisted of three stages: viewing of an informational documentary short movie with original English subtitles, documentation, and translation into Spanish. In order to confirm whether this subtitling practice raises students' motivation and, as a result, brings positive learning results, this study is based on the responses obtained in a questionnaire completed by the participants in the experiment. The main questions are related to the role of multiple semiotic systems as a support for textual comprehension and learning, and the acquisition of specialised terminology, as well as the students' motivation towards a simulation of a professional translation assignment
Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity
Aims: Obesity is characterized by a low-grade systemic inflammatory state and adipose tissue (AT) dysfunction, which predispose individuals to the development of insulin resistance (IR) and metabolic disease. However, a subset of obese individuals, referred to as metabolically healthy obese (MHO) individuals, are protected from obesity-associated metabolic abnormalities. Here, we aim at identifying molecular factors and pathways in adipocytes that are responsible for the progression from the insulin-sensitive to the insulin-resistant, metabolically unhealthy obese (MUHO) phenotype.
Results: Proteomic analysis of paired samples of adipocytes from subcutaneous (SC) and omental (OM) human AT revealed that both types of cells are altered in the MUHO state. Specifically, the glutathione redox cycle and other antioxidant defense systems as well as the protein-folding machinery were dysregulated and endoplasmic reticulum stress was increased in adipocytes from IR subjects. Moreover, proteasome activity was also compromised in adipocytes of MUHO individuals, which was associated with enhanced accumulation of oxidized and ubiquitinated proteins in these cells. Proteasome activity was also impaired in adipocytes of diet-induced obese mice and in 3T3-L1 adipocytes exposed to palmitate. In line with these data, proteasome inhibition significantly impaired insulin signaling in 3T3-L1 adipocytes.
Innovation: This study provides the first evidence of the occurrence of protein homeostasis deregulation in adipocytes in human obesity, which, together with oxidative damage, interferes with insulin signaling in these cells.
Conclusion: Our results suggest that proteasomal dysfunction and impaired proteostasis in adipocytes, resulting from protein oxidation and/or misfolding, constitute major pathogenic mechanisms in the development of IR in obesity
Well-posedness for the Schrödinger-Debye equation
Embargado hasta 01/01/2100.The Maxwell-Debye system describes the non resonant delayed interaction of an electromagnetic wave with a media. In these equations A denotes the envelope of a light wave that goes through a media which response is non resonant. This wave induces a change \nu of refractive index in the material (initially \eta_0 for an electromagnetic wave of frequency \omega_0) with a slight delay \tau. The magnitude and the sign of the nonlinear coupling of the matter with the wave is described by the parameter \eta_2. The light velocity in the vacuum is denoted by c and k denotes the wave
Characterisation of Sierra Morena citrus blossom honey (Citrus sp)
Embargado hasta 01/01/2100The citrus blossom honey of Sierra Morena (a mountain chain located in the south of Spain) has been
characterised by melissopalinological, physicochemical and sensorial analyses with the aim of establishing
criteria for a future Protected Designation of Origin, which includes citrus blossom honey as one of the
monofloral types produced in that region. Thus, a content in pollen of Citrus sp. ‡5%, Maurizio classes I and II was established, the accompanying pollen spectrum characteristic being that composed by the Myrtus, Echium, Lavandula, Reseda, Quercus, Olea, Crataegus and Cistus pollen types. The physicochemical parameters set were electrical conductivity £0.27 mS cm)1; diastase activity‡ 6 diastase number; colour £20 mm Pfund and coordinate CIE-Lab L = 89.72–95.18, a = )1.28 to 1.05, b = 16.99–21.79, C = 17–21.82, H = 87.23 –92.01 ; hydroximethylfurfural £10 mg kg)1; free acidity £28 milliequivalents ⁄ litre and moisture £18.5%. From the sensorial study, the following profile, based on the evaluation of attributes on a five-point scale, was obtained: colour white–pale yellow, fluidity (4.22), odour intensity (3.55), citrus blossom aroma ⁄ odour intensity (3.6 ⁄ 3.8), sweetness (3.14), acidity (2.36), freshness (61.5%) and persistence (2.9)
Deconstructing Gender Stereotypes in Western Tradition: No More Miss Perfect
Embargado hasta 01/01/2100Traditional feminine description and roles within Western literary and artistic cultural artifacts have tended to portray women in very a specific way – one which creates, disseminates and consolidates the gender roles which became foundational to heteropatriarchy and, sometimes, male chauvinism. As an example, women in poetry are often portrayed as fragile, sweet, romanticized creatures who ignite masculine desire or bolster male artists’ creativity. In this sense, most Western lyrical traditions present women as either objects of desire or inspirational muses. These secondary roles, which transform women into subalterns, can also be seen in other artistic manifestations, such as painting and sculpture or, more recently, films, TV fictions, graphic novels and videogames. This volume offers a multidisciplinary approach to the topic of feminine representation in literature and the arts, presenting womanhood from new perspectives which highlight feminine characters who have traditionally been neglected, misrepresented or reduced to marginal roles
Modern Ecopoetry: Reading the Palimpsest of the More-Than-Human World
Embargado hasta 01/01/2100Modern Ecopoetry: Reading the Palimpsest of the More-Than-Human World interrogates how humans’ relation to and confrontation with the nonhuman world is captured in or through poetry. It brings together contributions that explore how modern poetry addresses human beings’ relationship with the natural world, mirroring some of the most salient ecopoetic approaches to date. This collection is written from very di ferent corners of the globe and signi cantly adds to the existing body of work because, on the one hand, it continues to focus on the greening of poetry and, on the other, it expands its critical implementation in poetsnotnecessarilyincludedinmainstreamliterarycanons,bysetting them side by side regardless of their cultural background
Algunas características de la distribución de los asentamientos humanos en la provincia de Córdoba
Embargado hasta 01/01/2100Evolución de la distribución del poblamiento cordobés entre 1960 y 1991
Poblamiento y hábitat diseminado en el término de Cardeña: chozas y albergues ganaderos
Embargado hasta 01/01/2100El poblamiento del término municipal de Cardeña muestra unas características tan notorias como definitorias, de la misma manera que los paisajes agrarios en los que se inserta. El objetivo del presente trabajo es poner de manifiesto la singularidad de los modos de hábitat, prestando particular atención a las chozas y albergues ganaderos, menos conocidos, pero que hoy en día cobran una nueva importancia desde una renovada consideración del patrimonio y del paisaje