Repositorio de la Asociación Española de Neuropsiquiatría
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EDEBÎ METİNLERDE BELLEK VE MEKÂN: FATİH HARBİYE VE DOKUZUNCU HARİCİYE KOĞUŞU ROMANLARI ÜZERİNE BİR İNCELEME
No full textÖz: Bu çalışma, Peyami Safa’nın romanlarında bellek ve mekân ilişkisini ele almaktadır. Edebî metinler,hayal gücü veya doğrudan hayatın kendisinden olmak suretiyle bir bellekler sahasıdır. Ancak tecrübeettiklerini hayal edebilen yazar, metnini kaleme alırken bellekten yararlanmaktadır. Bu yüzdenedebiyat, bellekle ilgili çalışmalara önemli bir kaynak teşkil eder. Belleğin tutunduğu bir yeri işareteden mekân kavramı bu çalışmanın önemli bir inceleme nesnesidir. Çünkü bellekte yer eden hatıra,bilgi, tecrübe ve yaşanmışlıklar hep bir mekânın içinde gerçekleşir. Bunun için mekân, belleğidestekleyen bir kavram olmasının yanı sıra kendisi de aslında bir belleğe sahip olur. Bellek mekânlarıişte bu yaklaşımın sonucunda ortaya çıkar. Bellek mekânları, toplumsal kimliğin oluşumunda büyükbir etkiye sahiptir. Bu çalışma, aynı zamanda bellek-mekân ilişkisinin “kimlik” kavramını nasıl inşaettiğini ortaya çıkarmaya çalışmaktadır. Bireyin geldiği toplumun düşünce dünyası ile temeli atılankimlikler bellek mekânı yoluyla kendine süreklilik kazandırır. Peyami Safa’nın Fatih Harbiye romanı,doğu-batı, yeni-eski ve modern-gelenek ikiliklerini yansıtan ve kimlik kavramını da bu ikiliklerışığında ortaya koyan bir edebî eserdir. Bu çalışma Fatih Harbiye romanında bellek ve mekânilişkisinin nasıl bir kimlik inşa ettiğini incelemektedir. Psikolojik hayatın şekillenmesinde de belleğinve mekânın doğrudan ilişkisine dikkat çeken bu çalışmada Dokuzuncu Hariciye Koğuşu romanı kişiselbellek ve mekân ilişkisi için önemli bir örnek oluşturmaktadır.Öz: This study deals with the relationship between memory and space in Peyami Safa's novels. Literary texts are a field of memories by means of imagination or directly from life itself. The author, who can only imagine what he has experienced, takes advantage of memory while writing his text. Therefore, literature constitutes an important resource for studies related to memory. The concept of space that indicates a place where memory is held is an important research object of this study. Because memories, knowledge, experience and life experiences that make an impression in memory always take place in a space. For this, space, besides being a concept that supports memory, actually has a memory itself. Memory spaces emerge as a result of this approach. Memory spaces have a great influence on the formation of social identity. This study also tries to reveal how the memory-space relationship constructs the concept of "identity". Identities which are laid foundation with the world of thought of the society from which the individual comes gain continuity through the memory space. Fatih Harbiye, Peyami Safa’s novel, is a literary work that reflects the east-west, new-old and modern-tradition dualities and reveals the concept of identity in the light of these dualities. This study examines how the relationship between memory and space constructs an identity in Fatih Harbiye's novel. In this study, which draws attention to the direct relationship of memory and space in the shaping of psychological life, the novel Dokuzuncu Hariciye Koğuşu – Ninth Surgical Ward- is an important example for the relationship between personal memory and space
The uses of platelet indices, NLR (Neutrophil to Lymphocyte Ratio) and PLR (Platelet to Lymphocyte Ratio) in the predictive value diagnosis of benign and malignant masses of the parotid gland
No full textAim: Parotid gland tumors are uncommon in the head and neck surgery practice and difficult to surgically treat. Planning is very important, especially while planning parotid gland surgery, considering the difficulty of revision surgery. In this context, fine-needle aspiration cytology and radiological imaging stand out. However, preoperative diagnosis is sometimes difficult due to the nature of the salivary gland. At this point, additional methods in preoperative diagnosis are questioned. In our study, it was aimed to determine the surgical modality based on the predictive value in parotid benign and malignant masses with inexpensive, fast and easily obtainable platelet indices, NLR (Neutrophil to Lymphocyte Ratio) and PLR (Platelet to Lymphocyte Ratio).
Materials and Methods: The data of 236 patients who were operated on with parotid masses between 2010 and 2020 in our clinic were retrospectively analyzed. The data of the patients and the control group were evaluated statistically.
Results: A total of 356 participants were included in the study, including 236 patients who had undergone parotid gland surgery and a control group of 120 healthy individuals. When the data of the participants were reviewed, there was no significant difference between the groups in terms of age. In terms of sex, the number of the male patients was significantly higher than the female participants in the group with only parotid benign neoplasia. Based on the collected data, the mean MPV (Mean Platelet Volume) values were mean 9.1548 ± 1.55152 in the parotid cancer patient group (n1), 9.3810 ± 1.57825 in the inpatient group with parotid benign mass (n2) and 10.49250± 1.05314 in the control group (n3). The mean NLR values were found as 3.6395 ± 3.36035 in the parotid cancer patients (n1), 2.0145 ± 1.04293 in the parotid benign masses (n2) and 1.9689 ± 1.54979 in the control group (n3). The mean PDW (Platelet Distribution Width) values were found as 14.1258 ± 2.82536 in the parotid cancer patient group (n1), 14.5220 ±2.69823 in the parotid benign mass group (n2), and 12.5150 ± 2.49953 in the control group (n3).
Conclusion: In our study, we observed that the MPV, PDW and NLR values were significantly changed in the parotid gland tumors. We concluded that NLR values may be used effectively, especially in the predictive diagnosis of malignant masses and in planning surgery
Evaluation of the relationship between human brucellosis and pregnancy loss
No full textAim: Brucellosis is a zoonotic infection caused by bacteria of the genus Brucella. The disease causes genitourinary system
involvement and abortion, which is the most critical complication of the disease, in cattle. Although it is known to cause spontaneous
abortion, preterm birth and intrauterine death in humans, the number of systematic studies on the subject is limited. This study
compared the patients who experienced pregnancy loss and women who carried their pregnancy to term without any problems in
terms of serology for brucellosis in our region which is an endemic region.
Materials and Methods: The study was conducted in the Clinic of the Department of Obstetrics and Gynecology in Gaziantep
University Hospital between August 2012-June 2013. The study was conducted with 71 patients who experienced intrauterine
pregnancy loss and 109 women who carried their pregnancy to term without any problems as the control group, wherein all subjects
were aged between 18 and 40. These two groups were in a similar age group and had a similar gestational age.
Results: There were 4 (5,6%) subjects who were brucella-positive in the patient group and 1 (0,9%) subjects who were brucella-
positive in the control group according to the serology for brucellosis. C-reactive protein, erythrocyte sedimentation rate, aspartate
aminotransferase, abortus, and parity were significantly high in women who experienced pregnancy loss (p<0.05). The rate of living
in rural areas as well as the frequency of fever, chills, shivering and lower back pain was significantly high in the patient group.
When the patient group was divided into two subgroups according to the serology for brucella, patients with positive serology had a
significantly higher rate of joint pain and animal contact (livestock farming) history. Although there was no significant relationship
between brucella agglutination titration and pregnancy loss, the number of the brucellosis patients and agglutination titrations were
higher particularly in the group of women who experienced pregnancy loss.
Conclusion: Prospective studies that will be conducted with larger patient groups are required to better reveal the relationship
between pregnancy and brucellosis. Moreover, serology for brucella can be used as a screening method to provide early treatment
and prevent complications associated with brucellosis during pregnancy follow-up especially in endemic region
COVID-19 PANDEMİSİ GÖLGESİNDE YILLIK ÜCRETLİ İZİN HAKKI VE UYGULAMASI
No full textModern zamanların en ciddi insani, ekonomik ve sosyal krizini yaşadığımız bu günlerde, iş ilişkileri de bundan nasibini almıştır. Sadece ülkemizde değil dünya genelinde salgın nedeniyle üretim faaliyetleri ciddi yavaşlama göstermiş, birçok sektör ağır hasar görmüştür. Yaşanılan olumsuzlukları en aza indirmek ve muhtemel hak kayıplarını önlemek amacıyla alınan idari, hukuki ve mali önlemlerin yanı sıra işçi ve işverenler de taraflarını teşkil ettikleri iş ilişkilerinin devamını sağlamaya yönelik birtakım çarelere başvurmuşlardır. Bu kapsamda uygulamada sıklıkla başvurulan çarelerden biri de yıllık ücretli iznin pandemi ile mücadele aracı olarak kullanılması olmuştur. İlk bakışta işletmeler ve hükümet kaynakları üzerindeki ekonomik etkiyi azaltan ve her iki tarafın da menfaatine uygun bir çare ile karşı karşıya olunduğu izlenimi hasıl olsa da durum gerçekten böyle midir? Çalışmamızda, söz konusu yöntemin hukuka uygunluğu, yıllık ücretli izin kurumunun hukuki temeli, amacı ve işlevi ışığında öğretideki görüşlere, Fransız ve Alman Hukuku uygulamalarına ve ILO’nun konuya yaklaşımına yer verilmek suretiyle incelenmiş, böylelikle sorunun cevabı verilmiştir
The intracellular negative regulator genes of the Wnt signaling in imatinib treatment
No full textAim: Tyrosine kinase inhibitors are a targeted and successful treatment modalities in the treatment of Chronic Myeloid Leukemia (CML). Imatinib mesylate is the most common of these inhibitors, but resistance reactions limit its use. It is believed that regulators in the Wnt signaling pathway play an important role in the treatment of CML. The aim of this study is to investigate possible expression changes of intracellular negative regulator genes after imatinib mesylate treatment in chronic myeloid leukemia cell line.
Materials and Methods: Total RNA isolation was performed from K562 cells treated with Imatinib mesylate for 24 hours at 0.5 µM concentration and control native K562 cells. Following cDNA synthesis, expression changes of eight intracellular negative regulator genes were analyzed by Real-Time PCR.
Results: When the results were evaluated, it was determined that the expression of 5 genes increased and the expression of 3 genes decreased in K562 cells treated with imatinib.
Conclusion: When we suppressed Bcr-Abl with Imatinib in K562 cells, it was observed that there were changes in the expression levels of the intracellular negative regulator genes of the Wnt signaling pathway. These changes are important in defining new targets in CML treatment. To understand the roles of these negative regulators, it is important to conduct detailed research to develop new strategies for CML treatment
Analysis of Swimming, Swarming and Twitching Movements of Pseudomonas aeruginosa and its Recombinant Strain
No full textPseudomonas aeruginosa has several flagella at a single pole. Flagella helps bacteria to settle in solid food. They also perform the swimming movement, which is the movement in the liquid medium, with flagella. In the study, P. aeruginosa ATCC 10145 (NRRL B-771) and recombinant P. aeruginosa integrated into the chromosome of this bacterium by homologous recombination as a single copy vgb was used. While not observed, it was observed that its recombinant strain also had a pronounced movement of about 2-9 mm. While wild bacteria showed a twitching motion of about 0.2 mm, recombinant bacteria showed a tremor movement of 0.4-0.5 mm. While a small amount of significant swimming movement of approximately 0.2 mm was observed in wild bacteria, it was observed that there was a much more pronounced movement of 1.1-2.2 mm in recombinant bacteria. When the sliding motion was examined at the end of the 24-hour period, it was concluded that there was an obvious movement up to 30 times compared to the wild type of the recombinant strain. When the bacteria were examined in terms of the tremor action, it was found that the recombinant strain showed about 2.5 times more shivering movement than the wild type at the end of the 24-hour period. When the bacteria were observed in terms of the swimming test, it was observed that the recombinant strain made approximately 10 times more swimming movements than the wild type at the end of the 24-hour period
Contributions of the pioneers of the first generation of imam hatip to religious education and services in Turkey
No full textBu araştırmanın amacı, 1951 yılında ikinci kez açılan İmam Hatip Okullarında öğrenim gören ilk neslin, Türkiye'nin sosyal, kültürel ve dini alanlardaki hizmetleri ile din eğitimi, dini hayat ve din hizmetleri alanlarındaki değişim ve dönüşümlerdeki rolünün incelenmesidir. Bu konu kapsamında; ilk İmam Hatip neslinin profili; din eğitimi, din hizmetleri ve İmam Hatip Okulları hakkındaki görüşleri; bu alanlara olan katkıları; İmam Hatip Okulları ve Yüksek İslam Enstitüleri adına gerçekleştirilen hizmetler; ilk İmam Hatip neslinin öncülüğünde gerçekleşen teşkilatlanma çalışmaları ve yayıncılık faaliyetleri ile bilimsel alanda gerçekleştirilmiş olan çalışmalar ve Diyanet İşleri Başkanlığı bünyesinde yerine getirilmiş olan hizmetler tespit edilmeye çalışılmıştır. Araştırmada literatür tarama yöntemi kullanılmıştır. Araştırmada veri kaynağı olarak ilk İmam Hatip neslinin kaleme aldığı yazı ve eserlerin yanı sıra onları anlatan eserler ile mülakat, video kaydı vb. yollarla elde edilmiş ve yayınlanmış eserler incelenmiştir. Araştırma, 1951 yılında tekrar açılan İmam Hatip Okulları'nda yetişen ilk nesilden, ilgili literatürden ulaşılabilen isimlerle sınırlıdır. Araştırma sonunda tespit edilen sonuçlar şu şekildedir. İlk İmam Hatip nesli, benzer yaşantı ve çevrelere sahip, İmam Hatip Okullarına başlamadan önce çoğu yakın çevresinden az çok dini bilgiler almış ve Kur'an okumayı öğrenmiş kişilerden oluşmaktadır. Az bir kısmı hafız ve medrese eğitimi almıştır. Genel olarak İmam Hatip Okullarına başladıklarında yaşları genel öğrenim döneminin dışındadır. İmam Hatip Okulları ve Yüksek İslam Enstitüleri adına hizmetlerde bulunulmuştur. Çeşitli dernek, vakıf, cemiyet vb. oluşumlarla teşkilatlanma ve çeşitli dergi ve yayınevleriyle yayıncılık faaliyetlerinde bulunulmuştur. Üstlendikleri çeşitli görevlerde ülkenin sosyal, bilimsel, kültürel ve dini alanlarında önemli vazifeler ifa etmişlerdir.The purpose of this research is to study the role of the first generation that studied in İmam Hatip Schools that have opened for the second time in 1951 in Turkey's services in social, cultural, and religious fields, the change and transformations in religious education, religious life, and religious services. Within the scope of this subject; profile of the first İmam Hatip generation; their religious education, religious services, and their opinions on İmam Hatip Schools; contributions to these fields; services made in the name of İmam Hatip Schools and High Islamic Institutes; endeavours of organising with pioneering of first İmam Hatip generation, publishing activities, academic works, and services made as part of Directorate of Religious Affairs. Literature review method was used in the research. As data source in the research, writings and works of the first İmam Hatip generation as well as works that tell about them and works that are obtained and published by ways such as interviewing, videotaping, etc are used. The research is limited to the names from the first generation brought up in İmam Hatip Schools that can be reached from the related literature. The results determined at the end of the research are as follows. The first İmam Hatip generation are made up of persons that have similar lives and surroundings, more or less received basic religious knowledge from their immediate surroundings, and learnt to read Qur'an. A small portion have received hafiz and madrasah educations. In general, their ages are outside the period of general education when they start İmam Hatip Schools. Services have been made in the names of İmam Hatip Schools and High Islamic Institutes. Publishing and organising activities have been made with several entities such as associations, foundations, communities etc and several magazines and publishing houses. They have assumed significant duties in the country's social, academic, cultural, and religious fields with the several works they have taken on
Teacher Competencies and Qualifications for Support Services in Special Education Institutions
No full textThe purpose of this research is to discuss teacher competencies and qualifications in special education schools, special education classes, counseling and research centers (CRC), and special education rehabilitation centers (SERC) for providing educational support services (ESS) to individuals with special needs (SEN). This research was designed as qualitative research, and focus group interviews were chosen as a data collection technique. Sixty-two teachers working in CRCs, SERCs, special education schools, and classes participated in the research. A descriptive analysis method, which is used in qualitative research methods, was used in order to analyze the research data. The findings of the research were examined under six themes. It was found that the teachers (including special education teachers) had difficulty in teaching skills and concepts, interfering problem behaviors, providing sexual education with students and parent training, communicating with families in their native language, planning a student's individual education planning (IEP), assessing students formally and informally, and adapting to technology for the goals of IEP. Furthermore, in an inclusive education system, teachers do not/cannot offer support services to those with diverse languages, religions, cultures, and sexual orientations. On the other hand, this research concluded that teachers who spoke with students and families in their native language were more effective in improving students
Remission of Diabetes Mellitus in Two Patients with Maturity-Onset Diabetes of the Young After Bariatric Surgery
No full textWe present two cases with Maturity-onset diabetes of the young (MODY) undergoing bariatric surgery. Case 1: a 19-year-old woman using intensive insulin for type 1 diabetes mellitus (DM) was diagnosed with obesity. Body mass index (BMI) was 39.17 kg/m(2), fasting blood glucose (FBG) was 199 mg/dL, postprandial blood glucose (PPBG) was 239 mg/dL, glycated hemoglobin (HbA1c) was 11.1%, C-peptide (Cp) was 1.53 ng/mL, and antiGAD and ICA (islet cell autoantibody) were negative. Genetic analysis revealed a heterozygous mutation in HNF1A (MODY 3). We performed Roux-n-Y gastric bypass (RYGB). She discontinued insulin. Case 2: A 33-year-old woman using intensive insulin because of type 2 DM was diagnosed with obesity. BMI was 44.4 kg/m(2), FBG was 195 mg/dL, PPBG was 269 mg/dL, HbA1c was 9.4%, Cp was 1.89 ng/mL, and ICA and AntiGAD were negative. Genetic analysis revealed heterozygous mutation in KCNJ11 (MODY 13). RYGB was performed with an indication of morbid obesity. She discontinued insulin. RYGB was performed first in our cases for MODY. Improvement in glycemic regulation was higher than expected. A decision on bariatric surgery in patients with MODY should be made on the basis of the degree of obesity and glycemic status
Assessment of suicide probability and related factors in male incarcerated adolescents; a sample of reformatory center in Turkey
No full textObjective: Suicidal behavior in adolescents is an important public health problem, and it ranks first among the causes of prison deaths in incarcerated adolescents(IAs). The aim of this study is to determine the probability of suicide and associated risk factors in IAs. Method: Seventy-one male adolescents in a reformatory center were contrasted with a matched group of 71 male adolescent with no psychiatric disorder and no criminal record. Suicidal probability and psychiatric symptomatology were assessed with the Suicide Probability Scale, SA-45 Questionnaire, respectively. Results: It was determined that the probability of suicide was higher in IAs, and depression and hostility symptoms, the presence of another individual involved in delinquency in family had predictive effects. It was also found that there was a positive correlation between the probability of suicide and the number of delinquencies, the number of incarceration, and a negative correlation between attending to school or work while in reformatory and being visited by relatives while in reformatory. Conclusions: The results suggest that when assessing suicide risk for IAS, it may be useful to pay attention to those with symptoms of depression or hostility, those with multiple delinquencies or entrance to reformatory, and those who have family members involved in delinquency