Repositorio de la Asociación Española de Neuropsiquiatría
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Effects of the COVID-19 Pandemic on Pediatric Nasal Fractures
No full textObjectives Nasal bone fracture is a frequent entity consulted to the otolaryngologists, approximately accounting for 39% of all facial bone fractures. The most frequent mechanisms of injury consist of assault, sport-related injuries, falls, and motor vehicle accidents. In this study, we examined the effects of the COVID-19 pandemic on pediatric nasal fractures. Methods Children with nasal fracture who applied to Malatya Training and Research Hospital during the year before the first case and the following year were included in this study. Data of 172 patients for the pre-pandemic period and 79 patients for pandemic were available and included in the study. Demographic information, clinical features, nasal fracture etiology, nasal fracture type, type and time of intervention, and other accompanying pathologies were recorded. Results While falls was the leading cause of fracture etiology before the pandemic (64 patients [37.21%]), assault seems to be the leading cause during the pandemic period (27 children [34.18%]). In the pre-pandemic period, the intervention for patients with nasal fractures was performed on an average of 5 days, while this period was calculated as an average of 6 days during the pandemic period. When the 2 groups are compared in terms of nasal fracture intervention time, it was seen that the intervention time was statistically significantly later in the pandemic period (P < .001). According to the results of the analysis, the most cases in the pandemic period were seen in the fourth month, which indicated a-month period between 11 June and 11 July. Conclusions In conclusion, our number of nasal fracture cases was decreased during the pandemic period compared to the 1-year period before the pandemic. We observed the most common type IIA nasal fracture. We gave outpatient treatment to most of the patients. Our most common cause of fracture was assault. We intervened in our cases in an average of 6 days and preferred closed reduction most frequently. We could not find any study on the same subject in the literature, and we aimed to contribute to the literature with this study
The Effect of Cognitive Behavioral Therapy Based Psychoeducation on Psychological Well-being and Coping with Stres in Individuals Diagnosed with Panic Disorder
No full textAmaç: Bu araştırma panik bozukluk tanısı alan bireylerde bilişsel davranışçı terapi
temelli psikoeğitimin psikolojik iyi oluş ve stresle başa çıkmaya etkisi belirlemek amacıyla
yapıldı.
Materyal ve Metod: Araştırma ön test-son test kontrol gruplu randomize kontrollü
olarak Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi ve Dicle Üniversitesi
Hastanesi’nde Mayıs 2021-Temmuz 2022 tarihleri arasında yürütüldü. Araştırma,
Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi ve Dicle Üniversitesi Hastanesi
polikliniklerinde tedavi gören 105 panik bozukluk tanılı bireyle (51 deney, 54 kontrol)
tamamlandı. Veriler Tanıtıcı Özellikler Formu, Psikolojik İyi Oluş Ölçeği (PİOÖ) ve Stresle
Başa Çıkma Ölçeği (SBÇÖ) kullanılarak toplandı. Deney grubunda yer alan panik bozukluk
tanılı bireylere 8 oturumluk (haftada bir oturum) BDT temelli psikoeğitim grup eğitimi
şeklinde verildi, kontrol grubunda yer alan panik bozukluk tanılı bireylere herhangi bir
girişim uygulanmadı. Verilerin analizinde sayı, yüzde, ortalama, standart sapma, ki kare,
bağımlı ve bağımsız gruplarda t testi kullanıldı.
Bulgular: Deney grubunda yer alan panik bozukluk tanılı bireylerin BDT temelli
psikoeğitim sonrası psikolojik iyi oluş (41.37±4.06) ve stresle başa çıkma (86.72±6.84)
puanlarının kontrol grubunda yer alan panik bozukluk tanılı bireylerin psikolojik iyi oluş
(31.46±8.35) ve stresle başa çıkma (83.57±5.96) puanlarına göre arttığı belirlendi.
Araştırmada, BDT temelli psikoeğitimin deney grubunda yer alan panik bozukluk tanılı
bireylerin psikolojik iyi oluş ve stresle başa çıkma ölçeği ön test ve son test toplam puan
ortalaması arasındaki farkın istatistiksel olarak önemli olduğu belirlendi (p<0.05).
Sonuç: BDT temelli psikoeğitimin; panik bozukluk tanılı bireylerin psikolojik iyi
oluş ve stresle başa çıkma düzeylerini artırmada etkili olduğu bulundu.Aim: This study was conducted to determine the effect of cognitive behavioral
therapy based psychoeducation on psychological well-being and coping with stress in
individuals diagnosed with panic disorder.
Material and Method: The study was conducted in Diyarbakır Gazi Yaşargil
Training and Research Hospital and Dicle University Hospital between May 2021-
November 2021 as a randomized controlled trial with a pre-test post-test control group.
The study was completed with 105 individuals diagnosed with panic disorder (51
experimental, 54 control) who were treated in the outpatient clinics of Diyarbakır Gazi
Yaşargil Training and Research Hospital and Dicle University Hospital. Data were
collected using the Descriptive Characteristics Form, the Psychological Well-being Scale
and the Coping with Stress Scale. The individuals diagnosed with panic disorder in the
experimental group were given eight sessions (one session per week) CBT-based
psychoeducation in the form of group training, and no intervention was applied to
individuals diagnosed with panic disorder in the control group. Number, percentage, mean,
standard deviation, chi-square, t-test wasused in the analysis of the data.
Results: The level of psychological well-being (41.37±4.06) and coping with stress
(86.72±6.84) scores of individuals diagnosed with panic disorder in the experimental group
after CBT-based psychoeducation increased compared to the level of psychological well being (31.46±8.35) and coping with stress (83.57±5.96) scores of individuals diagnosed
with panic disorder in the control group. In the study, it was determined that the difference
between the psychological well-being and coping with stress scales pretest and posttest
total score averanges of individuals diagnosed with panic disorder in the experimental
group of CBT-based psychoeducation was statistically significant (p<0.05).
Conclusion: CBT-based psychoeducation applied to individuals diagnosed with
panic disorder; It was determined that it was effective in increasing the level of
psychological well-being and the level of coping with stress in these individuals
Electrochemical and in Silico Investigations of the Interaction between Nitro Blue Tetrazolium Chloride and Bovine Serum Albumin
No full textThe binding ability of the drug on its interaction with the protein will also significantly affect the apparent volume of distribution of the drugs and, in many cases the rate of elimination of the drugs. The interactions of proteins and other molecules are a fascinating topic applied to surface technologies and sensors. Therefore, it is aimed to determine the NBTCand to elucidate its interaction with Bovine Serum Albumin (BSA) by electrochemical and in silico studies in this paper. The reduction in BSA oxidation signals measured by differential pulse voltammetry upon incubation with different NBTC concentrations indicated that NBTC was bound to BSA. In addition, in silico (molecular modeling and molecular dynamics) studies have been conducted on the interactions of NBTC with proteins in plasma. As a result of the in silico studies investigated the interactions of NBTC with serum albumin, its binding affinity, and the dynamic process in the binding state. In silico studies showed that NBTC binds to BSA with high affinity (with-7.986 kcal/mol docking score), and this binding was stable (with a 3.0 average RMSD value). Eventually, the results of the electrochemical and modeling studies were perfectly matched
Investigation of the mechanical and tribological properties of polymer matrix hybrid composites under different environmental conditions
No full textBu çalışmada; vakum destekli reçine transfer kalıplama metodu ile üretilen sekiz katmanlı tabakalı cam/epoksi (GFRP), karbon/epoksi (CFRP) ve cam-karbon epoksi hibrit (GCFRP) kompozitlerin yapay deniz suyu, motor yağı ve dizel yakıt ortamında 30,60 ve 90 gün boyunca yaşlandırılma etkisinin kompozit yapılardaki mekanik ve tribolojik davranışlarına etkisi incelenmiştir. Kompozitlerin mekanik dayanımlarını incelemek için çekme, üç nokta eğilme, düşük hızlı darbe testi ve basma testleri yapılmıştır. Tribolojik davranışları incelemek için ise kuru kayma aşınma testleri yapılmıştır. Farklı sıvı ortamlarında yaşlandırılan kompozitlerin kütlece absorpsiyon yüzdelerine bakıldığında en yüksek kütlesel absorpsiyonuna sahip olan kompozitlerin CFRP kompozitler olduğu, en düşük kütlesel yüzde absorpsiyonuna sahip kompozitlerin GFRP kompozitler olduğu hesaplanmıştır. Tüm ortam koşullarında Çekme dayanımı, eğilme dayanımı ve basma dayanımının en yüksek olduğu kompozit tipi karbon/epoksi kompozitler olduğu tespit edilmiştir. Düşük hızlı darbe dayanımının en yüksek olduğu kompozit tipi ise cam/epoksi kompozitler olmuştur. Kompozitlerin tribolojik davranışları incelendiğinde cam elyafın spesifik aşınma oranının karbon elyaftan fazla olduğu sonucuna varılmıştır. Cam-karbon hibrit şekilde üretilmiş kompozitlerin çekme mukavemeti, basma mukavemeti ve düşük hızlı darbe mukavemetini artırırken, eğilme mukavemetini azalttığı sonucuna varılmıştır. Ortam yaşlandırma etkilerine bakıldığında, yaşlandırma süresi arttıkça kompozitlerin mekanik ve tribolojik mukavemetlerinin azaldığı etkilerini azaldığı görülmüştür. Tüm yaşlandırma ortamları koşullarına bakıldığında mekanik dayanıklılığı en çok etkileyen ve değiştiren ortamın deniz suyu yaşlandırma ortamı olduğu tespit edilmiştir.In this study; eight-layer laminated glass/epoxy (GFRP), carbon/epoxy (CFRP) and glass-carbon epoxy hybrid (GCFRP) composites produced by vacuum assisted resin transfer molding method for 30, 60 and 90 days in artificial seawater, engine oil and diesel fuel environment. The effect of the aging effect on the mechanical and tribological behavior of composite structures was investigated. Tensile, three-point bending, low-speed impact test and compression tests were performed to examine the mechanical strength of the composites. Dry slip wear tests were carried out to examine the tribological behaviors. Considering the mass absorption percentages of the composites aged in different liquid environments, it was calculated that the composites with the highest mass absorption were CFRP composites, and the composites with the lowest mass percent absorption were GFRP composites. It has been determined that composite type carbon/epoxy composites have the highest tensile strength, bending strength and compressive strength in all ambient conditions. The composite type with the highest low-velocity impact strength was glass/epoxy composites. When the tribological behaviors of the composites were examined, it was concluded that the specific wear rate of glass fiber was higher than carbon fiber. It was concluded that while glass-carbon hybrid composites increase tensile strength, compressive strength and low velocity impact strength, they decrease flexural strength. Considering the effects of ambient aging, it was observed that the mechanical and tribological strengths of the composites decreased as the aging time increased. When the conditions of all aging environments are examined, it has been determined that the environment that affects and changes the mechanical strength the most is the seawater aging environment
Improving performance of bituminous pavement layers with vermiculite, perlite, lime and calcite additives
No full textThe bearing resistance of asphalt pavements decreases due to the high temperature and long loading times and many distortions occur with tracks. Mineral additives are used to prevent the formation of wheel marks and other deformations in bituminous hot mixtures. Some of the additives are used to improve the blend properties by modifying the bitumen and some are directly involved in the admixture to enhance the engineering characteristics of the pavement layer. In this study, vermiculite, perlite, lime and calcite minerals were added directly to the mixture at the ratio of 0.5%, 1%, 1.5%, 2% and 2.5% of aggregate weight. Bitumen content, porosity, stability and flow values of the samples were determined by Marshall method. The values obtained from doped samples were compared with the reference sample. As a result of experimental study, it was revealed that vermiculite, perlite, lime and calcite mineral additives increased the durability of the asphalt mixtures and these additives may obstruct the wheel tracks on the surface
On statistical manifolds
No full textvDört bölümden oluşan bu yüksek lisans tezinin birinci bölümü literatür taraması için girişe ayrılmıştır. ˙Ikinci bölüm diğer bölümlerin daha iyi anlaşılabilmesi için bazı temel kavramlardan oluşmaktadır ki bu bölüm Riemann manifoldları ve Riemann submersiyonları adı altında iki alt başlıktan ibarettir. Riemann submersiyonlarında O'Neill tarafından tanımlanan tensörler tanıtılmış, bu tensörlerin özellikleri, geometrik anlamları ve kovaryant türevleri incelenmiştir. Üçüncü ve dördüncü bölüm tezin ana kısmını oluşturmaktadır: Üçüncü bölümde istatistiksel manifoldlar tanıtılmış, eğrilikleri ve özelliklerinden bahsedilmiştir. Dördüncü bölümde ise istatistiksel submersiyonlar ve kosimplektik-benzeri istatistiksel submersiyonlar verildikten sonra kosimplektik-benzeri istatistiksel submersiyonların anti-invaryantlığı incelenmiş, örnekle desteklenmiş ve temel manifold üzerindeki distribüsyonların integrallenebilirlik ve tamamen geodeziklik durumları araştırılmıştır. Anahtar Kelimeler: ˙Istatistiksel Yapı, Afin Konneksiyon, Eşlenik Konneksiyon.The first chapter of this master's thesis, which consists of four chapters, has reserved for an introduction to literature review. The second chapter has some basic definitions and theorems for a better understanding of the other chapter, which consists of two subsections called Riemann manifolds and Riemann submersions.Tensors defined by O'Neill in Riemann submersions has been introduced. The properties, geometric meanings and covariant derivatives of these tensors have been studied. The third and fourth chapters have constituted the main part of the thesis: In the third chapter, statistical manifolds have introduced, their curvatures and properties have mentioned. In the fourth chapter, after statistical submersions and cosimplectic-like statistical submersions have given, the anti-invariance of cosymplectic-like statistical submersions has examined, supported by an example, and integrability and totally geodesicness of the distributions on the total space have obtained. Keywords: Statistical Structure, Affine Connection, Conjugate Connection
Concomittant Liver Transplantation and Low Anterior Resection in Patient with Neuroendocrine Tumor and Chronic Hepatitis B Infection
No full text[Abstract Not Available
Okul Müdürlerinin Ders Denetim Yeterlikleri ile Öğretmenlerin Ders Denetimi Kaygı Düzeyleri Arasındaki İlişkinin İncelenmesi
No full textBu araştırmanın 3 amacı vardır. Birinci amacı, okul müdürlerinin ders denetim yeterliklerini ve öğretmenlerin ders denetim kaygı düzeylerini öğretmen görüşlerine göre ortaya koymaktır. İkinci amacı, ders denetim yeterlik ve kaygı düzeylerine ilişkin öğretmen görüşlerini bağımsız değişkenler açısından incelemektir. Üçüncü amaç ise, okul müdürlerinin ders denetim yeterlikleri ile öğretmenlerin ders denetim kaygı düzeyleri arasındaki ilişkiyi ortaya çıkarmaktır. Araştırmanın evrenini 2020-2021 eğitimöğretim yılında Malatya ilinin Battalgazi ve Yeşilyurt ilçelerindeki resmi okullarda görev yapan 10315 öğretmen oluşturmaktadır. Örnekleme dâhil edilen 410 öğretmen kolayda örnekleme yöntemiyle belirlenmiştir. Araştırmanın verileri, araştırmacılar tarafından geliştirilen “Okul Müdürlerinin Ders Denetim Yeterlik Ölçeği” ve “Öğretmenlerin Ders Denetim Kaygı Ölçeği” ile toplanmıştır. Araştırmada elde edilen verilerin analizinde öncelikle betimsel istatistik hesaplamaları yapılmıştır. Okul müdürlerinin ders denetim yeterlikleri ile öğretmenlerin ders denetim kaygı düzeylerinin cinsiyet, branş, kıdem, okul türü, eğitim düzeyi ve okulda görev yapan öğretmen sayısı değişkenleri bakımından anlamlı farklılık gösterip göstermediğini belirleyebilmek için bağımsız gruplar için t testi ve tek yönlü varyans analizi yapılmıştır. Okul müdürlerinin ders denetim yeterlik düzeyleri ile öğretmenlerin ders denetim kaygı düzeyleri arasındaki ilişkiyi belirlemek amacıyla basit doğrusal regresyon analizi uygulanmıştır. Araştırmada öğretmenlerin, okul müdürlerinin ders denetim yeterliklerini “yüksek düzeyde” gördükleri ve ders denetimlerine ilişkin kaygı düzeylerinin “orta düzeyde” olduğu saptanmıştır. Kadın öğretmenlerin erkek öğretmenlere göre, ortaokul öğretmenlerinin ilkokul öğretmenlerine göre ve öğretmen sayısı 50 ve üzeri olan okullarda görev yapan öğretmenlerin öğretmen sayısı 50’den az olan okullardaki öğretmenlere göre okul müdürlerinin ders denetim yeterlik düzeylerini daha yüksek buldukları belirlenmiştir. Araştırmada okul müdürlerinin ders denetim yeterlik düzeylerinin, öğretmenlerin ders denetim kaygı düzeyleri için anlamlı bir yordayıcı olduğu belirlenmiştir
Frequency of Direct Oral Anticoagulants Usage in Acute Pulmonary Thromboembolism Treatment in Turkey (TUPEDO)
No full textBackground: Direct oral anticoagulants (DOACs) have been used in acute pulmonary thromboembolism as an alternative to warfarin due to drug interactions, narrow therapeutic range, and necessary close International Normalized Ratio (INR) monitoring. Phase 3 study results have reported that these drugs are at least as effective as warfarin and beneficial in terms of bleeding; however, studies that present up-to-date life data are necessary. Aims: To evaluate the frequency of using DOACs, which are prescribed with a limited number of indications in our country, and real-life data results. Study Design: Cross-sectional study Methods: This cross-sectional survey collected the clinical data (history, current treatment, treatment duration, etc.) of patients with pulmonary thromboembolism and who applied to the physician for follow-up between October 15, 2019, and March 15, 2020. The researchers kept the patient records sequentially. Results: Data from 836 patients with acute pulmonary thromboembolism from 25 centers were collected, and DOAC was used in 320 (38.5%) of them. The most preferred DOAC was rivaroxaban (n = 294, 91.9%). DOAC was mostly preferred because it could not provide an effective INR level with warfarin (n=133, 41.6%). Bleeding was observed in 13 (4%) patients. Conclusion: The use of direct oral anticoagulants is becoming almost as widespread as conventional therapy. Real-life data results are important for their contribution to clinical practice
Evaluation of the relationship of the time of vesicoureteral reflux between renal scar development and endoscopic treatment success in early childhood
No full textAim: It is aimed to evaluate the effect of reflux time in primary VUR in terms of predicting endoscopic treatment success and treatment timing in VUR management. Vesicoureteral reflux (VUR) is an important cause of urinary tract infection and chronic renal disease. Voiding cystourethrography (VCUG) is the gold standard diagnostic test in the diagnosis of VUR. In recent years, new parameters related to VCUG have been more objectively studied to evaluate the clinical prognosis. Materials and Methods: In our study, the records and imaging findings of children with primary VUR who underwent VCUG examination between 2012 and 2019, who were treated with endoscopic injections, were retrospectively reviewed. Forty-one children (67 renal units) were included in our study. Patients with preoperative VCUG, urinary ultrasonography, dimercaptosuccinic acid (DMSA) renal scan, and post-operative control VCUG were included in this study. Results: Patients with preoperative VUR grade 1-2 were divided into two groups as “low grade” and patients with stage 3-4-5 as “high grade”. In the general patient pop- ulation, endoscopic success rates in terms of renal unit deficit were found to be 46.3% (31/67). When the subgroup was analyzed, the endoscopic treatment success rate was 72.2% (13/18) in the low-grade group, versus 36.7% (18/49) in the high-grade group (p = 0.010). In the multivariate logistic regression analysis performed to identify indepen- dent predictors of scarring, reflux degree and reflux time were found to be independent predictors of scarring. Conclusion: In our study, we found that in VCUG evaluated preoperatively, VUR time as well as VUR grade were effective on endoscopic success rate and scar development. Based on these results, it could be thought that VUR time may be effective in selecting the best candidates for surgery and in the management and timing of treatment of VUR patients