Repositorio de la Asociación Española de Neuropsiquiatría
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No es ansiedad, no es depresión, pero “estoy mal”: Javier Padilla, Marta Carmona. Malestamos. Cuando estar mal es un problema colectivo.
No full textEn un tiempo en el que los libros luchan por encontrar un espacio entre laliteratura digital, es sorprendente que un pequeño ensayo como Malestamos hayallegado a una sexta edición. Su explicación, sin duda, tiene que ver con Javier Padilla,que lleva más de una década debatiendo sobre las conexiones de la salud con elámbito de la política, la filosofía o los movimientos sociales, y con su coautora, MartaCarmona, psiquiatra, feminista y activista no solo en la salud mental, sino en la vida
La psicopatología como estabilizador de la psiquiatría
No full textThe way of constructing psychiatric experience and determining it has been carried out on the basis of naturalistic and psychologistic positions, which are still the dominant ones after almost two hundred years. However, the fact of assimilating psychiatric knowledge to a mere empirical-analytical science has brought nothing but instability, something that is forcefully evident throughout history and the discriminating insufficiency of the current clinical practice. It is necessary to consider the philosophical implications of approaching this open empirical field where subjectivity cannot be segregated and is articulated on a pluralistic and discontinuous ontology. It is postulated that only psychopathology, in its exercise as a procedure both logical and intellectual, allows to relate the different planes of reality in which it develops and to try to close its field in order to provide psychiatry with the necessary stability required for its clinical praxis.La forma de construir la experiencia psiquiátrica y determinarla se ha llevado a cabo a partir de posiciones naturalistas y psicologistas que siguen siendo las dominantes después de casi doscientos años. Sin embargo, el hecho de asimilar el conocimiento psiquiátrico a una mera ciencia empírico-analítica no ha deparado más que inestabilidad, algo que queda a la vista de forma contundente a lo largo de la historia y de la insuficiencia discriminante de la clínica actual. Se requiere considerar las implicaciones filosóficas que supone el abordaje de ese campo empírico abierto donde la subjetividad no puede ser segregada y se articula sobre una ontología pluralista y discontinua. Se postula que solo la psicopatología, en su ejercicio como procedimiento a la vez lógico e intelectivo, permite relacionar los distintos planos de realidad en que se desenvuelve y tratar de cerrar su campo para dotar a la psiquiatría de la necesaria estabilidad requerida de cara a su praxis clínica
¿Cómo actualizar la propuesta psicopatológica de Castilla del Pino (y no morir en el intento)?
No full textCarlos Castilla del Pino’s work on psychopathology is mostly unknown by the new generations of residents. This can be accounted for by reasons that are external and internal to his work. However, questions posed by Castilla in his psychopathology work may have validity, irrespective of the answers he proposed, which can be criticised. Some strategies to update Castilla’s proposals that can be used on teaching descriptive psychopathology to trainees are presented.La obra psicopatológica de Carlos Castilla del Pino es poco conocida por las nuevas generaciones de residentes. Existen razones externas e internas a la propia obra que podrían servir de explicación de este hecho. Sin embargo, las cuestiones planteadas por Castilla del Pino en su obra psicopatológica pueden tener plena vigencia, independientemente de que las respuestas por él ofrecidas puedan ser objeto de análisis crítico. Se proponen algunas estrategias para actualizar los planteamientos del autor en la enseñanza de la psicopatología descriptiva de los profesionales en formación
Occupation of Kyrgyzstan by Russians (second half of 19th century)
No full textKırgızistan'nın Ruslar tarafından işgalini (19. Yüzyılın İkinci Yarısı) konu alan tez çalışmamızda, Sovyet Dönemi bilim adamlarının bu olayı nasıl değerlendirdikleri ve olaya hangi perspektiften baktıkları farklı açılardan incelenmiştir. Araştırmamızın en önemli kaynağını, "Türkistan Derlemesi" oluşturmaktadır. Zira bu derlemede Hokand Hanlığı ve onun yıkılış süreci ile Rusya İmparatorluğu'nun yürüttüğü siyasî yapılar hakkında bilgiler yer almaktadır. Ayrıca bu derlemede, Türkistan ve Türk halklarının eski, orta, modern çağdaki sosyal hayatı, ekonomik durumu, kültürü, dini ve cografyası hakkındaki değerli bilğilere de yer verilmektedir. Kırgızistan'ın en önemli bilim adamlarından B. Camgerçinov'un, "Kırgızistan'ın gönüllü olarak Rusya'nın himayesi altına girdiğini" ifade ettiği bilinmektedir. O dönemlerde başka bir teoriyi ifade etmek veya düşünmek mümkün değildi. Kırgızistan'ın bağımsızlığını kazanmasına kadar, Turdakun Usubaliyev'in döneminde de bu teorinin doğruluğu kabul edilmiştir. Kırgızistan'ın 19. Yüzyılda Rus hakimiyeti altına girmesi, yakın tarihteki Kırgız bilim adamları tarafından farklı bakış açılarıyla ele alınmış ve bu konu birinci teoriye aykırı ifadelerle açıklanmıştır. Kırgız bilim adamlarından T. Kenesarıyev, T. Çorotegin, T. Ömürbekov gibi ünlü tarihçiler yaptıkları araştırmalar sonucunda, Kırgızistan'ın gönüllü olarak Rus İmparatorluğu'nun himayesine girmediğini, hatta Güney Kırgızistan'ın kanlı bir şekilde fethedildiğini belirtmişlerdir. Bu kavram, dönemin etkin siyasî yapısının ilkeleriyle çelişiyor gibi görünse de, aslında dünya tarihi açısından yapılan araştırmalar sonucunda ortaya atılmış bir görüştür. Rusya'nın sömürgeleştirmek istediği Kırgızistan, 19. yüzyılın ilk çeyreğinden itibaren Rusya'nın ilgisini çekmeye başlamıştır. O dönemde var olan hakimiyet altına alma politikası, 1860'larda daha da güçlenmiştir. Kırgız topraklarını Rus egemenliğine sokma politikası, 1876 yılında Hokand Hanlığı'nın yıkılmasıyla gerçekleşmiştir. Anahtar Kelimeler: Rus İşgali, Türkistan Derlemesi, Sömürge, Hokand HanlığıIn our thesis on the occupation of Kyrgyzstan by the Russians (Second Half of the 19th Century), how the scientists of the Soviet Era evaluated this event and from which perspective they looked at the event were examined from different perspectives. The most important source of our research is the "Turkestan Collection". Because in this compilation, there is information about the Kokand Khanate and its collapse process and the political structures carried out by the Russian Empire. In addition, in this compilation, valuable information about the social life, economic situation, culture, religion and geography of Turkestan and Turkic peoples in the old, middle and modern ages are also included. It is known that B. Camgerchinov, one of the most important scientists of Kyrgyzstan, stated that "Kyrgyzstan voluntarily came under the protection of Russia". At that time, it was not possible to express or think about any other theory. Until the independence of Kyrgyzstan, this theory was accepted during the period of Turdakun Usubaliyev. Kyrgyzstan's coming under Russian domination in the 19th century has been discussed by Kyrgyz scholars from different perspectives in recent history and this issue has been explained with statements contrary to the first theory. Famous historians such as T. Kenesariyev, T. Çorotegin, T. Ömürbekov, among the Kyrgyz scientists, stated as a result of their research that Kyrgyzstan did not voluntarily fall under the protection of the Russian Empire, and that even Southern Kyrgyzstan was conquered in a bloody way. Although this concept seems to contradict the principles of the effective political structure of the period, it is actually an opinion that was put forward as a result of researches made in terms of world history. Kyrgyzstan, which Russia wanted to colonize, started to attract the attention of Russia since the first quarter of the 19th century. The policy of domination, which existed at that time, became even stronger in the 1860s. The policy of putting the Kyrgyz lands under Russian rule was realized with the collapse of the Kokand Khanate in 1876. Keywords: Russian İnvasion, Turkestan Collection, Colony, Khanate of Kokan
The Ethics of Bribery: Theoretical and Empirical Studies
No full textWhile most people assume that all bribery is unethical, the literature provides examples and philosophical arguments to support the proposition that some bribery may actually be ethical, based on utilitarian grounds. This book provides a theoretical and empirical examination of bribery from an ethical perspective. It examines empirical data from over 80 countries and reports on attitudes toward bribery examining demographic variables such as gender, age, ethnicity, education, income level, religion and social class. Multi-country comparisons are provided to determine whether views toward bribery differ by geographic location. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Effects of flipped learning-based guitar instruction on motivation, attitude, and accompaniment skills
No full textThe purpose of this research is to determine the effects of flipped learning-based guitar instruction on students' motivation, attitude, and accompaniment skills. This experimental study consisted of 26 students who were attending the lectures at Fine Arts Education Department of Music Teaching. A random sampling technique was employed to select 14 students for the experimental group and 12 students for the control group. Data collection tools used included instrument motivation scale, attitude scale towards instrument, and guitar accompaniment evaluation form. During the twelve-week intervention, both the control group and the experimental group trained for one hour each week. Students in the experimental group performed significantly higher accompaniment skills than students in the control group. The flipped learning model was found to be more effective than traditional learning method. Based on the results of the study, some recommendations were made for future studies. © 2023, Pharmaceutical Association of Serbia. All rights reserved.The manuscript was produced from the PhD dissertation of the first author completed at the İnonu University under the supervision of the second author
Pirofillit Cevherinden Alümina Üretimine Zenginleştirme Yöntemlerinin Etkisi
No full textBu çalışmada, pirofillit cevherinden alüminyum (Al) kazanımı üzerine farklı zenginleştirme yöntemlerinin etkisi araştırılmıştır. Zenginleştirme yöntemleri pirofillitin doğal hidrofob yapısından dolayı flotasyon yöntemi, kırılganlık farklılığından dolayı ise Aşındırmalı Yıkama (AY) yöntemi kullanılmıştır. Zenginleştirme sonucu konsantre numunelere HCl ile liç işlemi yapılmış, liç sonucu çözeltiye geçen Al miktarları karşılaştırılarak değerlendirilmiştir. Pirofillit cevherinin AY yöntemi ile zenginleştirilmesi sonucu %54.79 verimle %27.44 Al2O3 tenörlü bir konsantre, flotasyon yöntemi ile ise %30.49 verimle %28.05 Al2O3 tenörlü bir konsantre elde edilmiştir. Buna göre zenginleştirme verimi açısından AY yöntemi daha verimli iken liç verimi açısından ise flotasyon yönteminin daha verimli olduğu belirlenmiştir. Tüvenan cevhere göre nihai alümina miktarı ve saflığı birlikte değerlendirildiğinde doğrudan liç ve AY konsantresi değerlerinin birbirine yakın olduğu belirlenmiştir. Sonuç olarak pirofillit cevherinden alümina üretimi için ayrıntılı ekonomik analiz yapılarak uygun yöntemin belirlenmesinin daha doğru olacağı değerlendirilmektedir
Effectiveness of game-based core exercise in children with non-neuropathic bladder dysfunction and comparison to biofeedback therapy
No full textObjectives This study was planned to evaluate the effectiveness of game-based core exercises in children diagnosed with non-neuropathic bladder dysfunction and compare this effectiveness to that of the biofeedback treatment method. Methods The study included 48 children, aged 6-13 years, who were diagnosed with non-neuropathic bladder dysfunction. The children satisfying the inclusion criteria were selected by drawing lots from the population with the method of nonprobability random sampling. The patients were divided into three groups: group I, game-based core stabilization exercise training; group II, biofeedback program; and group III, game-based core stabilization exercise training in addition to the biofeedback program. The Dysfunctional Voiding and Incontinence Symptom Scale (DVISS) scores and uroflowmetry values of the patients were evaluated before and after the treatment. Results The mean age of the participants was 8.81 +/- 2.08 years. There was a statistically significant difference between the pretreatment and post-treatment DVISS scores in all three groups (p < .05). However, no significant difference was found among the groups. There was no statistically significant difference in the uroflowmetry results of the patients in group I and II before and after the treatment. In group III, the time to maximum flow rate after treatment was significantly reduced, and the average flow rate was significantly increased. Conclusions According to the results of this study, the use of game-based exercises along with biofeedback treatment may reduce DVISS scores in children with non-neuropathic bladder dysfunction. A combination of the two methods may have positively affected the uroflowmetry results of the patients. We think that game-based exercises will contribute to the literature as a new treatment option in the treatment of non-neuropathic bladder dysfunction.Scientific Projects Coordination Unit of Inonu University [TYL2019-1835]Scientific Projects Coordination Unit of Inonu University, Grant/Award Number: TYL2019-183
Extraction and Characterization of Linden Tree Seed Oil Grown in Malatya with Different Solvents
No full textIn this study, the characterization study of the oil of linden seeds obtained by the extraction method was carried out. The outer shells of linden seeds collected from Malatya region in August 2018 were cleaned before extraction. Hexane, ethyl alcohol and acetone were used as solvents. Elemental analysis, XRD (X-Ray Diffraction), SEM (Scanning Electron Microscopy), ash determination and saponification number determinations were performed for characterization processes. After the analysis, the oil yield with ethyl alcohol was determined as 33% by weight with acetone, 28.65% for hexane and 28% for acetone. In linden seed fatty acid, it was determined as oleic acid: 27.442 for acetone, 30.852 for hexane, 10.955 for acetone by weight, 11.929 for hexane, linoleic acid: 51.188 for acetone, 44.145 for hexane. The soap number value was determined as 232.48 mg KOH/g for ethyl alcohol, 176.72 mgKOH/g for hexane and 246.94 mg KOH/g oil for acetone. While the ash determination value was 5.755% for the seed, the shell ash was determined as 2.1% differently
EMT and Inflammation: Crossroads in HCC
No full textHepatocellular carcinoma is one of the major causes of cancer-related deaths worldwide and is associated with several inflammatory mediators, since 90% of HCCs occur based on chronic hepatitis B or C, alcoholism or increasingly metabolic syndrome-associated inflammation. EMT is a physiological process, with coordinated changes in epithelial gene signatures and is regulated by multiple factors, including cytokines and growth factors such as TGF beta, EGF, and FGF. Recent reports propose a strong association between EMT and inflammation, which is also correlated with tumor aggressiveness and poor outcomes. Cellular heterogeneity results collectively as an outcome of EMT, inflammation, and the tumor microenvironment, and it plays a fundamental role in the progression, complexity of cancer, and chemoresistance. In this review, we highlight recent developments concerning the association of EMT and inflammation in the context of HCC progression. Identifying potential EMT-related biomarkers and understanding EMT regulatory molecules will likely contribute to promising developments in clinical practice and will be a valuable tool for predicting metastasis in general and specifically in HCC.NIH [CA 82723]; TUBITAK [114Z245, 117Z223, 120N556, 219Z034]This work was supported in part by NIH grant number CA 82723 (to BIC) and TUBITAK grant numbers 114Z245, 117Z223, 120N556, and 219Z034 (to H.A)