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    Sustainable and Inclusive Growth Commission Inclusive Economy Working Group Evidence Report

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    Confidential evidence report to the Sustainable and Inclusive Growth Commission.This report sets out an overview of the evidence collated by the Inclusive Economy Working Group (IEWG) in line with the timetable provided by the Sustainable and Inclusive Growth Commission (SIGC). It commences with an outline of the IEWG remit as agreed following consultation. It then explores the nature of inclusive growth (IG) and the legislative context. The report then moves onto a discussion of the data collected on inequalities at a sub-regional, local authority and national level before setting out the activities which are already being rolled out in relation to the IG agenda at a local level. Finally, the report will set out exemplar approaches towards IG beyond the sub-region before exploring how the evidence collated will inform next steps for the IEWG feeding into the SIGC timetable for action and the SIGC Report which was launched in November 2022

    Doctors and their families

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    Benbow, S. M., Doctors and their families, Australasian Psychiatry (Journal Volume Number 31 and Issue Number 2) pp. 124-126. Copyright © [2023] (The Royal Australian and New Zealand College of Psychiatrists). Reprinted by permission of SAGE Publications.This article reflects on the relationship between doctors and their families and how it influences a doctor’s health, well-being and practice and the health and well-being of other family members. It uses an established model for conceptualising this recursive relationship, drawing on systemic and communications theory, coordinated management of meaning. The article invites doctors to reflect on relational influences between them and their families across the course of their career and following retirement. Conclusion: Families are important to, and influence, the well-being of their doctor-members. Likewise, doctors are important to, and influence, the health and well-being of their families

    Arrival Neighborhoods in Europe since the mid-19th Century: Migrations, Cities, Infrastructures

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    This is an Accepted Manuscript of a book chapter published by Routledge in Arrival Neighborhoods in Europe since the mid-19th Century: Migrations, Cities, Infrastructures [26/08/2024], available online: https://www.routledge.com/Arrival-Neighborhoods-in-Europe-since-the-mid-19th-Century-Migrations/Templin/p/book/9781032320502London’s East End – a quarter buttressing the city’s docklands – has long been a place of arrival for migrants both domestic and foreign. Characterised in the 19th century by dense housing, tenement blocks, large factories, and low-grade workshops, it was also an area subject to pervasive stigmatisation by on-lookers. It was a stigmatisation which drew upon the area’s reputation as a ‘notorious’ slum quarter and a ‘hotbed’ for crime, complicated by its established status as a reception centre for ‘foreigners’. The large-scale arrival and settlement of Jews from Eastern Europe after 1880 cemented but also extended and diversified such narratives. The rhetoric of the ‘slum’ was now codified with a new, distinctly antisemitic way of describing and degenerating space. The East End slum quarter became ‘the ghetto’, textile factories became ‘sweatshops’, and the East End itself was imaginatively transformed to become ‘little Jerusalem’. Journalists, philanthropists, politicians, novelists, flaneurs and voyeurs all contributed to this spatial lexicon. So too did members of the established Jewish community in Britain both internalise and regurgitate such language as a means to distinguish themselves from their ‘alien’ brethren. This chapter explores the emergence and evolution of this linguistic landscape within cultural discourse of the period, arguing that it was the pre-existing identity of the East End itself as a place apart which allowed this vocabulary to form

    Mindfulness for performance and wellbeing in the police: linking individual and organizational outcomes

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    This document is the Accepted Manuscript version of a published work that appeared in final form in [Review of Public Personnel Administration]. To access the final edited and published work see http://dx.doi.org/10.1177/0734371X231155794This article reports on the largest randomized control trial (with follow-up) to examine the effects of mindfulness among police officers and staff. The benefits of mindfulness for wellbeing are established, but less is known about long-term impact on employee wellbeing and the implications of individual outcomes at organizational level. In the RCT, both the wellbeing and performance of users of two mindfulness apps over 24 weeks improved as compared to a control group. In responding to calls for consideration of relevance alongside rigour in public administration field experiments, the study also investigated how a large-scale wellbeing intervention was implemented and applied cost-effectiveness methodology to link individual and organizational outcomes and demonstrate cost savings. This additional contextualisation showed how to improve implementation of wellbeing interventions for public personnel and demonstrated a method for rigorously assessing whether interventions deliver on both an individual and organizational level

    BCR-ABL Tyrosine Kinase Inhibitors as Candidates for the Treatment of COVID-19: Molecular Docking, Pharmacophore Modeling, ADMET Studies

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    The novel coronavirus pandemic (COVID-19) caused by SARS-CoV-2 has affected more than 53 million individuals worldwide. Currently, there is a dire need to develop or find potential drugs that can treat SARS-CoV-2 infection. One of the standard methods to accelerate drug discovery and development in pandemics is to screen currently available medications against the critical therapeutic targets to find potential therapeutic agents. The literature has pointed out to the 3CLpro and RdRp proteins as the most important proteins involved in viral replications. In the present study, we used an in-silico modeling approach to examine the affinity of six tyrosine kinases inhibitors (TKIs), Imatinib, Ponatinib, Nilotinib, Gefitinib, Erlotinib, and Dasatinibagainst the 3CLpro and RdRp by calculating the energy balance. The six tested TKIs had energy balance values of more than -7 Kcal/mol for both viral target proteins. Nilotinib and Ponatinib showed the highest affinity for 3CLpro (-8.32, -8.16, respectively) while Dasatinib, Ponatinib, and Imatinib presented the strongest binding toRdRp(-14.50, -10.57, -9.46, respectively). Based on these findings, we recommend future evaluations of TKIs for SARs-CoV-2 infection in-vitro and further testing in clinical trials

    L1 scheme for solving an inverse problem subject to a fractional diffusion equation

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    This paper considers the temporal discretization of an inverse problem subject to a time fractional diffusion equation. Firstly, the convergence of the L1 scheme is established with an arbitrary sectorial operator of spectral angle ⟨ π ∕ 2, that is the resolvent set of this operator contains {z ∈ ℂ ⧵ {0} ∶ |Arg | ⟨ θ} for some π ∕ 2 ⟨ θ ⟨ π. The relationship between the time fractional order α ε (0,1) and the constants in the error estimates is precisely characterized, revealing that the L1 scheme is robust as α approaches 1. Then an inverse problem of a fractional diffusion equation is analyzed, and the convergence analysis of a temporal discretization of this inverse problem is given. Finally, numerical results are provided to confirm the theoretical results

    Brexit and the stratified uses of national and European Union citizenship

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    Sredanovic, D., & Della Puppa, F. Brexit and the stratified uses of national and European Union citizenship, Current Sociology (Journal Volume Number 71 and Issue Number 5) pp. 725–742. Copyright © [2021] (The Authors). Reprinted by permission of SAGE Publications.In this article the authors explore how Brexit changes the social meanings and uses of formal national and EU citizenship and how these meanings and uses are stratified, including by migratory experience, class and age. They do so through in-depth interviews with Britons in Belgium, EU27 citizens ‘by birth’ residing in the UK, and Bangladeshis who naturalised in Italy before moving to the UK. The article highlights the differences both between the three groups and within the groups, along lines of class and age, in the expectations regarding rights linked to citizenship, in the salience of different rights (e.g. freedom of movement, access to welfare, voting), and in the availability of alternative resources to contain the impact of Brexit. The authors argue that the Brexit process not only highlights the value of citizenship as well as the added value of a citizenship of an EU member state, but that it also reveals how the value of citizenships is internally stratified

    ‘What Is? What If? What Next?’ Why institutions must urgently identify, support, and celebrate their student-parents – and imagining a world in which they do so

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    This document is the Accepted Manuscript version of a published work that appeared in final form in [Widening Participation and Lifelong Learning]. To access the final edited and published work see http://dx.doi.org/10.5456/WPLL.24.3.165Students who have dependent children are ‘relatively invisible in the policy and physical spaces of universities’ (Moreau and Kerner, 2015: p.4), are ‘ignored or only briefly mentioned’ in governmental communications (Moreau, 2014: p2), and are impossible to track in terms of entrance to, performance at, or attrition rate from, higher education. There is no obligation on institutions in England and Wales to compile data on their students’ family circumstances (Moreau, 2014), and as such student-parents at such institutions can remain unidentified and unsupported throughout their higher education journey. With the aim of adding urgency to the calls to take the first step in supporting student parents, this paper uses Hopkins’ (Hopkins, R., 2019; 2022a) ‘what is? what if? what next?’ method to stimulate conversation about this overlooked cohort and to visualise the ways in which student-parents could be supported and celebrated by their institutions if they were visible participants in higher education. The article underlines why the higher education sector should collect data on student-parents (‘what is’); presents a vision of the university of the future which collects data from, and thus is able to support and celebrate, its student-parent population (‘what if’); and urges higher education institutions, in the absence of a national requirement to do so, to compile data on an institutional level which in turn facilitates the retention, progression, achievement and satisfaction of this committed and motivated cohort (‘what next’)

    Researching poverty and austerity: Theoretical approaches, methodologies and policy applications

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    This is an Accepted Manuscript of a book chapter published by Routledge in [Researching poverty and austerity: Theoretical approaches, methodologies and policy applications] on [30th November 2023], available online: https://www.routledge.com/Researching-Poverty-and-Austerity-Theoretical-Approaches-Methodologies/Moraes-McEachern-OLoughlin/p/book/9781032127774In this chapter we reflect on how theoretical perspectives, such as liminality, can be useful for researchers seeking to understand and alleviate lived experiences of poverty. We draw on how we deployed liminality theory in a recently published paper (Moraes et al., 2021), to conceptualise lived experiences of food insecurity as transitional; as fluctuating between phases of everyday food access and food marketplace exclusion. By using liminality as an exemplar theoretical perspective, we discuss a concept that we developed and termed paraliminality, a hybrid of two types of liminality phenomena that is both empowering and generative of a lasting form of indeterminate state. In reflecting upon paraliminality, we argue that it can illuminate the social mechanisms, practices and spaces that co-construct people’s more enduring, but fluid, experiences and phases of food insecurity and food access efforts. We illustrate the main theoretical arguments being made with data from our study of food insecurity (McEachern et al., 2020), involving interviews with people who were experiencing food insecurity, volunteers who were providing access to food aid, and fieldwork photographs of the independent foodbanks and pantries who took part in the research. The chapter contributes to food insecurity, poverty and marketplace exclusion scholarship by reflecting on the importance of using theoretical lenses in qualitative research work, and by reflecting on, and deploying, an illustrative research project to explain how theory can be used and why it matters

    How poems go beyond: Advocating the use of poetic representation for therapeutic practitioner researchers in qualitative research

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    This is a pre-publication version of the following article: [Buxton, C. (2023). How poems go beyond: Advocating the use of poetic representation for therapeutic practitioner researchers in qualitative research. Qualitative Methods in Psychology Bulletin, issue 35, 47-59. https://doi.org/10.53841/bpsqmip.2023.1.35.47]This article focuses on how poetic representation of research offers therapeutic practitioners distinct ways to engage audiences, leading to a deeper, more dynamic and relationally based understanding of the lived experience of another than other research outputs allow. Methodologically, it advocates that using poetic representation presents practitioners with an accessible, flexible, and therefore more viable way of presenting research findings that can encourage research confidence and engagement. It briefly describes the use of Gee’s (1991) psycholinguistic framework in creating poetic form from unstructured narrative interviews with therapists who work with psychological trauma. This framework allows the researcher to readily draw out content that represents the most meaningful aspects of interview material. Using extracts from resultant poems, it explores the ways in which this form of data presentation offers the ability to connect with readers deeply and evocatively, ultimately leading to potential change in the reader’s world as a result

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