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Influence of silane coating and graphene oxide integration on the magnetothermal behaviors of la1-xsrxmno3 nanoparticles
No full textIn this study, La1-xSrxMnO3 (x = 0.27, 0.3, 0.33) magnetic nanoparticles (MNPs) were synthesized and then these nanoparticles synthesized in the core-shell structure were coated with silane for potential magnetic hyperthermia applications. In order to provide support material for the coated magnetic nanoparticles, silane-coated hybrid magnetic nanoparticles were obtained by producing graphene oxide (GO) nanoflakes. The structural and magnetic properties and magnetothermal properties of these structures were investigated. It was observed that the structure of the silane-coated magnetic nanoparticles remained intact and did not show any degradation compared to the uncoated materials. In addition, the highest saturation magnetization (MS) value was observed in the sample doped with x = 0.30. This value indicated that the heating power would be higher than the other doped samples in the specific absorption ratio (SAR) measurements. In this context, the heating amount in the silane-coated samples showed a slight decrease compared to the uncoated samples. Despite the decrease in the SAR values of the integrated samples by incorporating GO into the coated MNPs, it is anticipated that effective results will be obtained for practical applications with the advantage of increasing the thermal conductivity of GO.Scientific and Technological Research Council of Turkey (TUBITAK) [221S429]; TUBITAKThis study was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) under the Grant Number 221S429. The authors thank TUBITAK for their support
Bir esnek çalışma modeli olarak uzaktan çalışmanın kritik olaylar tekniği ile analizi
No full textBu çalışma, uzaktan çalışma deneyimi elde etmiş kişilerin deneyimlerine odaklanarak, uzaktan çalışma modellerinin tarihsel gelişimi, günümüzdeki yeri ve gelecekteki potansiyel etkilerini ele alarak çalışma hayatındaki dönüşümü analiz etmektedir. Geleneksel çalışma biçimlerinin yerini giderek daha esnek ve dijital temelli çalışma modellerine bırakması, bireyler, kurumlar ve toplum üzerinde çeşitli etkiler yaratmaktadır. Özellikle son yıllarda teknolojik ilerlemeler ve küresel krizler (örneğin COVID-19 pandemisi), uzaktan çalışmayı kaçınılmaz bir uygulama haline getirmiştir. Bu bağlamda, araştırmada uzaktan çalışmanın olumlu ve olumsuz yönleri detaylı bir şekilde incelenmiş; bu çalışma modelinin sürdürülebilirliği üzerine öneriler sunulmuştur.
Araştırmada, nitel araştırmalarda kullanılan amaçlı örnekleme yöntemlerinden kartopu örnekleme tekniği kullanılmıştır. Kritik olaylar tekniği ile katılımcıların konu ile ilgili deneyimleri derinlemesine irdelemek amaçlanmıştır. Aynı zamanda bu teknik ile yenilik getirmek istenmektedir. Araştırma kapsamında toplam 30 katılımcı ile Denizli ilinde yüz yüze görüşme gerçekleştirilmiştir. Görüşmelerden elde edilen verilerden toplam 26 adet kod oluşturulmuştur. Belirlenen kodlardan, kategori ve temalar oluşturularak tekniğe uygun olarak çalışma verileri açıklanmıştır.
Araştırma sonucunda uzaktan çalışmanın sürdürülebilir bir şekilde uygulanabilmesi, bireylerin ve kurumların bu dönüşüme adapte olmalarını sağlayacak yapısal düzenlemeler ve çözümler geliştirilmesiyle mümkün olduğunu ortaya çıkarmıştır. Uzaktan çalışmanın en önemli avantajları arasında zaman ve mekân esnekliği, çalışanların verimliliğinde artış, iş-yaşam dengesinin sağlanması ve işletmeler açısından maliyet tasarrufu yer almaktadır. Bununla birlikte, uzaktan çalışma modelinde ortaya çıkan iletişim eksiklikleri, sosyal izolasyon, teknolojik altyapı yetersizlikleri ve çalışanların iş yükü ile özel yaşam sınırlarının bulanıklaşması önemli sorunlar olarak tespit edilmiştir.This study analyzes the transformation of work life by focusing on the experiences of individuals with remote working experience, examining the historical development, current status, and potential future impacts of remote work models. The gradual replacement of traditional working methods with more flexible and digital-based work models has generated various effects on individuals, organizations, and society. Particularly in recent years, technological advancements and global crises (e.g., the COVID-19 pandemic) have made remote work an inevitable practice. Within this context, the study examines the advantages and disadvantages of remote work in detail and offers recommendations for the sustainability of this working model.
The study employs the snowball sampling technique, one of the purposive sampling methods used in qualitative research. The critical incident technique is utilized to deeply explore participants' experiences related to the subject and to introduce innovative insights through this approach. Face-to-face interviews were conducted with 30 participants in Denizli province, and a total of 26 codes were created from the data obtained through these interviews. Based on the identified codes, categories and themes were developed, and the findings were explained in accordance with the adopted methodology.
The results of the study reveal that the sustainable implementation of remote work depends on the development of structural arrangements and solutions that enable individuals and organizations to adapt to this transformation. Among the most significant advantages of remote work are time and spatial flexibility, increased employee productivity, the achievement of work-life balance, and cost savings for organizations. However, key challenges identified within the remote work model include communication gaps, social isolation, inadequacies in technological infrastructure, and the blurring of boundaries between work and private life
Biosorption Study of Cdsup>2+/Sup> Ions Onto Activated Carbon Prepared From Posidonia Oceanica Seagrass: Kinetics and Thermodynamics Studies
No full textIn this research, the synthesis and characterization of activated carbon from Posidonia oceanica seagrass have been carried out through physical activation (AC-PO) as a biosorbent for Cd2+ ions in solution. The physical activation process was carried out at a temperature of 600 degrees C and physical activation was carried out using the water-steam activator. The objective of the AC-PO biosorption test on Cd2+ ions is to ascertain the optimal contact time, the impact of temperature, the influence of concentration, the ideal dose, and pH, in addition to the kinetic model and biosorption isotherm pattern. The biosorption kinetics data of Cd2+ ions on AC-PO tend to follow a pseudo-second-order kinetic model. The biosorption isotherms of Cd2+ ions on AC-PO tend to follow the Langmuir, Freundlich, Temkin, and D-R isotherm models with a correlation coefficient (R-2) of >0.9910. The thermodynamic parameters such as Delta G(o), Delta H-o, and Delta S-o were calculated for the Cd2+ ion, and it was determined that the biosorption was spontaneous and endothermic
Use of albumin and CRP related i̇mmuno-nutritional markers for prediction of locoregional response to treatment i̇n unresectable hepatocellular carcinoma
No full textPurpose: We examined the relationship between albumin and C reactive protein (CRP)-related inflammation markers such as Controlling nutritional status (Conut) score, lymphocyte-albumin factor (LA), albumin-bilirubin score (ALBI), highly sensitive modified Glasgow prognostic score (Hs-mGPS), Glasgow prognostic score (GPS) and locoregional treatment response in HCC. Materials and methods: One hundred and eighty HCC patients and 63 patients who underwent locoregional therapy were included in this study. Routine laboratory tests between the fourth and eighth week after treatment were recorded and albumin and CRP-related immuno-nutrition scores were calculated. Cut-off values from the literature were used. The predictive and prognostic value of these markers for overall survival (OS) and disease-free survival (DFS) after treatment were analyzed. Results: The mean age was 63 years (min-max:26-87) and 59 (93.7%) of the patients were male. The mean follow-up period was 25 months and 53 patients were deceased (84.1%). Median overall survival (mOS):18.56 months (min-max:13.13-23.99); median disease-free survival (mDFS):7 months (min-max:3.63-10.37) after locoregional treatment. Age (p=0.019), Conut (p=0.001), GPS (p=0.028), Hs-mGPS (p=0.012), LA (p=0.017) and ALBI (p=0.002) were significantly correlated with mOS. Conut (p=0.002), GPS (p0.001), Hs-mGPS (p=0.002), LA (p=0.002) and ALBI (p=0.001) were significantly correlated with mDFS. Multivariate analysis revealed that those aged ≥65 years (HR:2.10; 95% CI:1.02-4.30; p=0.042) and those who received no systemic therapy (HR:4.11; 95% CI:1.35-12.56; p=0.013) had an increased risk of death (p0.001). Another significant result was that a GPS of '2' (HR:6.62; 95% CI:1.13-38.62; p=0.036) predicted a higher risk of progression (p0.001). Conclusion: In this study, we found that age, Conut score, GPS, HsmGPS, LA and ALBI score significantly predicted mOS and mDFS in locoregionally treated HCC patients. All these results suggest that our prognostic modelling may be useful in clinical practice. © 2025, Pamukkale University. All rights reserved
The Pediatric Nurse From the Perspective of Children With Hospitalization Experience: a Qualitative Study
No full textPurpose: This study aims to determine the perceptions of children with hospital experience about pediatric nurses. Design: A descriptive qualitative design guided by a phenomenological approach was used. Settings: A purposive sampling technique was used to recruit 17 children aged 7-18 who had experienced hospitalization in pediatric clinics. Methods: The study employed rigorous research methods, including semi-structured interviews and thematic analyses, to ensure the validity and reliability of the findings. Data were analyzed using the MAXQDA20 program, resulting in the identification of 322 codes. Five themes and 16 sub-themes were created from the obtained codes, providing a comprehensive understanding of the children's perceptions. The COREQ checklist was followed in this study. Results: Five themes were created: the image of the pediatric nurse in children's minds, children's expectations from pediatric nurses, the characteristics of the pediatric nurse, children's perception of whether nurses care about or do not care about them, the topics nurses talk about with children. Conclusions: Pediatric nurses have positive and negative images of children, children have child-specific expectations from pediatric nurses, such as playing and chatting. Some nurses' attitudes and behaviors create the perception that children care about or do not care about them. Practice implications: This study's findings have a practical impact on pediatric nursing. In addition to their treatment and care practices, nurses can communicate more with children, spend more time with them, play more games with them. This way, the needs and expectations specific to children's age periods are met, leading to improved patient outcomes. (c) 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies
Gastroözofageal reflü tanılı bireyler ve sağlıklı bireylerin fiziksel aktivite düzeyleri ve fonksiyonel kapasitelerinin karşılaştırılması
No full textBu çalışma Gastroözofageal Reflü tanılı bireyler ve sağlıklı bireylerin fiziksel aktivite ve fonksiyonel kapasitesini karşılaştırmak amacıyla planlandı.
Çalışmaya 18-75 yaş aralığında 100 gönüllü dahil edilmiştir. Değerlendirmede 2 grup yer almıştır: Gastroözofageal Reflü tanılı bireyler “Grup 1” (n=50), sağlıklı bireyler “Grup 2” (n=50) olarak adlandırılmıştır. Çalışmadaki veriler; Katılımcı Bilgi Formu (Ek-4), UFAA-KF (Uluslararası Fiziksel Aktivite Anketi- Kısa Form) (Ek-6), DASI (DASI Aktivite Durum İndeksi (Ek-2), Reflü Semptom İndeksi (Ek-5), GÖRH Skalası (Ek-3) ile toplanmıştır. Bireylerin fiziksel aktivite durumları UFAA-KF (Uluslararası Fiziksel Aktivite Anketi- Kısa Form) ile; fonksiyonel kapasite durumları DASI Aktivite Durum (DASI) aracılığıyla incelenmiştir.
UFAA Şiddetli, UFAA Yürüme, UFAA Toplam, UFAA Oturma puanlarının incelenmesinde Gastroözofageal Reflü tanılı ve sağlıklı grupları arasında istatistiksel olarak anlamlı bir farklılık tespit edilmemiştir. (p >0,05).
UFAA Orta puanlarının incelenmesinde ise Gastroözofageal Reflü Tanılı ve sağlıklı grupları arasında istatistiksel olarak anlamlı farklılık olduğu görülmüştür. Gastroözofageal Reflü Tanılı kişilerin UFAA Orta puanlarının sağlıklı grubundaki kişilere göre daha yüksek olduğu tespit edilmiştir. (p 0,05).
DASIVO2 ve DASImets puanlarının incelenmesinde Gastroözofageal Reflü Tanılı ve sağlıklı grupları arasında istatistiksel olarak anlamlı bir farklılık tespit edilmemiştir. (p >0,05). Yine de GÖRH Tanılı gruptaki bireylerin DASIV02 ve DASImets sonuçları Sağlıklı gruptaki bireylerin sonucuna göre daha düşük olduğu fark edilmiştir.
Yaş ortalaması daha yüksek ileri yaş grubunu barındıran karma bir yaş yelpezesi ile aynı çalışmaların yapılması gerekmektedir.This study was planned to compare the physical activity and functional capacity of individuals diagnosed with Gastroesophageal Reflux and healthy individuals.The study included 100 volunteers between the ages of 18-75. There were 2 groups in the evaluation: Individuals with Gastroesophageal Reflux diagnosis were named as “Group 1” (n=50), and healthy individuals were named as “Group 2” (n=50). Data in the study were collected using the Participant Information Form (Appendix-4), IPAQ-Short Form (International Physical Activity Questionnaire-Short Form) (Appendix-6), DASI (DASI Activity Status Index (Appendix-2), Reflux Symptom Index (Appendix-5), GERD Scale (Appendix-3). The physical activity status of the individuals was examined with IPAQ-Short Form (International Physical Activity Questionnaire-Short Form); and their functional capacity status was examined with DASI Activity Status (DASI).
In the examination of IPAQ Severe, IPAQ Walking, IPAQ Total, IPAQ Sitting scores, no statistically significant difference was found between the Gastroesophageal Reflux diagnosed and healthy groups. (p>0.05)
In the examination of IPAQ Intermediate scores, it was observed that there was a statistically significant difference between the Gastroesophageal Reflux Diagnosed and healthy groups. It was determined that the IPAQ Intermediate scores of people with Gastroesophageal Reflux Diagnosed were higher than those in the healthy group. (p 0.05).In the examination of DASIVO2 and DASImets scores, no statistically significant difference was found between the Gastroesophageal Reflux Diagnosed and healthy groups (p>0.05). However, it was noticed that the DASIV02 and DASImets results in the GERD Diagnosed group were lower than the growth in the healthy group.The same studies need to be conducted with a mixed age group that includes an older age group with a higher average age
Longitudinal Impact of the Act-Based Positive Psychology Intervention To Improve Happiness, Mental Health, and Well-Being
No full textUzun, Kivanc/0000-0002-6816-1789; Arslan, Gokmen/0000-0001-9427-1554; Aydogdu, Umut/0000-0001-9880-6480This study aims to examine the effectiveness of ACT-based positive psychology intervention on young people's mental health and well-being. Existing literature offers limited insights into the impacts of ACT-based PPIs, particularly concerning young people. The study explores the potential of this intervention to enhance positive psychological outcomes such as subjective well-being, self-compassion, and optimism, while reducing negative psychological outcomes like pessimism, anxiety, depressive symptoms, and somatic symptoms, and improving resilience. Conducted at a state university, the study involved 42 participants between the ages of 19 and 23 who were assigned to experimental (n = 20) and control (n = 22) group. The experimental group participated in an 8-week ACT-based PPI program. Employing a longitudinal experimental design, the study included a pre-test, post-test, and a follow-up test approximately two years later. Results indicated that the experimental group experienced significant improvements in positive psychological outcomes and reductions in negative outcomes, with the effects sustained during the follow-up period. Notably, long-term enhancements in resilience and self-compassion were observed. Overall, this study provides important evidence of the effectiveness of ACT-based PPI in promoting young people's long-term outcomes, with implications for developing intervention programs to support their mental health and well-being.We thank the participants of this study and those who developed the measures used.Mehmet Akif Ersoy Universit
A Complex Clinical Situation in Polycystic Ovary Syndrome: Hair-An Syndrome ' Report
No full textHyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome is a distinct and uncommon form of polycystic ovarian syndrome. It manifests through hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans (AN), along with symptoms like acne, hirsutism, irregular menstruation, and other androgen-related issues. A 17-year-old female with a history of childhood obesity and irregular menstrual cycles presented with weight gain and amenorrhea. Previously assessed for hirsutism with a Ferriman-Gallwey score of 14, she was found to have hepatic steatosis, ovarian cysts, and IR. She was advised to lose weight and prescribed metformin but did not adhere to the treatment. Four years later, she returned with further weight gain and hirsutism and was diagnosed with androgenetic alopecia. The presence of AN, HA, and severe IR led to a diagnosis of HAIR-AN syndrome, and she was placed under observation. We used next-generation sequencing (NGS) to screen 70 genes for mutation and identify relevant genetic variations. The investigation targeted all exons and exon-intron junctions in genes, including ACOX1, GM2A, ACSF3, and others. Bioinformatics tools and in silico algorithms were used to assess the impact of the variants. No significant mutations associated with the patient's symptoms were identified. HAIR-AN syndrome can present in various forms and should be considered in cases of unexplained AN and menstrual irregularities. Early detection, diagnosis, and treatment of HAIR-AN syndrome can alleviate symptoms and improve patients' quality of life. This case presentation aims to evaluate the findings of a HAIR-AN syndrome that became very severe due to treatment noncompliance
A Psychometric Study in Children With Juvenile Idiopathic Arthritis: Pain Catastrophizing Scale-Child (pcs-C) Turkish
No full textCankaya, Ozge/0000-0002-2116-8924; Yuksel, Selcuk/0000-0001-9415-1640The research aimed to determine the psychometric properties of the Turkish Pain Catastrophizing Scale-Child (PCS-CTr) in children with Juvenile Idiopathic Arthritis (JIA). The study included 125 children (75 with JIA and 50 without JIA). PCS-CTr has been adapted following international translation steps. PCS-CTr was administered twice to 31 children with JIA at 7-14-day intervals. Validity was tested by confirmatory factor analysis and gold standard measures with the Pediatric Quality of Life Inventory and the Visual Analogue Scale. Cronbach's alpha (alpha) for internal consistency and Intraclass Correlation Coefficient (ICC) for test-retest reliability were used. Also, the PCS-CTr scores were compared to each group. Construct (RMSEA = 0.069, CFI = 0.962, TLI = 0.943, X2/df = 1.352) and concurrent validity (r=-0.533) were found good. The final model fits three factors with 13 items. Cronbach's alpha (0.706-0.912) and ICC values (0.649-0.900) were moderate to high. The psychometric quality of the PCS-CTr is good. A reliable and valid assessment tool could be used for children with JIA to assess pain catastrophizing. We recommend the PCS-CTr as a tool for assessing JIA children's pain catastrophizing
One curve ve one reci döner eğe sistemleri ile gerçekleştirilen kök kanal tedavisinin değerlendirilmesi ve yaşam kalitesi üzerine etkisi: Bir anket çalışması
No full textAmaç:
Bu çalışma, One Curve ( ve One Reci ( döner alet sistemleri ile
yapılan kök kanal tedavisinin hastaların yaşam kalitesine etkilerini OHIP 14 ölçeği
kullanarak değerlendirmeyi ve postoperatif ağrı seviyelerinin bu kalite üzerindeki
etkisini incelemeyi amaçlamaktadır.
Yöntem:
Çalışma, Pam ukkale Üniversitesi Endodonti Anabilim Dalı’na
başvuran, yaşları 1 8 66 arasında değişen, belirli dahil etme kriterlerine uyan 8 4 hasta
üzerinde gerçekleştir ildi . Hastalar randomize bir şekilde iki gruba (n=4 2 ) ayrıl dı : Grup
1’de O C , Grup 2’de ise O R eğe si stemi kullanılmıştır. Tüm tedaviler, aynı operatör
tarafından tek seansta, standart protokollere uygun şekilde gerçekleştiril di . Kanallar
%2,5 sodyum hipoklorit ( solüsyonu ve %17 Etilendiamintetraasetik asit
EDTA solüsyonu ile yıkan dı . S onrasında Sealapex (Kerr, Scafati, kanal patı ve
g utta perka ile doldurul du , kompozit üst dolgusu ile tedavi tamamlan dı . Postoperatif ağrı
seviyeleri 24. saatte VAS (Görsel Analog (0 100) ile değerlendirilirken, yaşam
kalitesi OHIP 14 ölçeği ile 24. s aat, 3. ay, 6. ay ve 12. aylarda ölçül dü . İstatiksel
analizler için Mann Whitney U testi ile birlikte Bonferroni ve Tukey ileri düzey testleri
kullanıl dı p ≤
Bulgular
Gru plar arasında ortalama yaş ( p =0,881 ) ve cinsiyet p =1,000 )
dağılımlarında anlamlı bir fark bulunmadı. Cinsiyet ile hasta yaşam konforu arasındaki
ilişki değerlendirildiğinde anlamlı bir fark bulunmadı. Gruplar arası nda 24. saat
postoperatif ağrı VAS skorları arasında anlamlı bir fark bulunmadı p 0,312 İki grup
arasında 24. saat psikolojik huzursuzluk ve OHIP skorları arasında istatistiksel olarak
anlamlı farklar belirlen di ve O R grubunun, O C grubuna göre ilk günde daha fazla
psikolojik rahatsızlık oluşturd uğu gözlemlen di . O R g rubunda 24. saat ve 12. a y
arasındaki puan değişi minin, O C grubuna göre anlamlı olarak daha fazla olduğu
bulundu. p =0,906
Sonuç: O C ve O R sistemlerinin postoperatif 3. a y, 6. a y ve 12. ay yaşam konforu
açısından benzer olduğu bulundu. Ancak O C , O R grubuna göre özellikle ilk gün oluşan
psikolojik rahatsızlık konusunda daha üstünd ü . O R grubunun ilk gün OHIP skorunun
III
yüksek olmasına bağlı olarak, O
yüksek olmasına bağlı olarak, ORR grubunun ilk gün ve 12. ay arasındaki OHIP skor grubunun ilk gün ve 12. ay arasındaki OHIP skor değişimi Odeğişimi OCC grubuna göre daha fazlagrubuna göre daha fazlaydıydı. . İki test grubunİki test grubunda da, OHda da, OHIIP skorlarındaki P skorlarındaki değişimin esas olarak farklı enstrümantasyon tekniklerinden kaynaklandığı sonucuna değişimin esas olarak farklı enstrümantasyon tekniklerinden kaynaklandığı sonucuna varabiliriz.varabiliriz.Objective: This study aims to evaluate the effects of root canal treatments
performed with One Curve ( and One Reci ( rotary file systems on patients’
quality of life using the OHIP 14 scale and to examine the impact of postoperative pain
levels on this qualit y.
Method: The study was conducted on 8 4 patients, aged between 18 and 66, who
applied to the Department of Endodontics at Pamukkale University and met specific
inclusion criteria. The patients were randomly divided into two groups (n=4 2 ): Group 1
was treated with the OC file system, and Group 2 with the OR file system. All
treatments were performed by the same operator in a single session according to
standard protocols. The canals were irrigated with 2.5% sodium hypochlorite solution
an d 17% ethylenediaminetetraacetic acid (EDTA) solution. Subsequently, the root canals
were filled using Sealapex (Kerr, Scafati, Italy) sealer and gutta percha, and the
treatment was completed with a composite restoration. Postoperative pain levels were
ass essed using the VAS (0 100) ( Visual Analog Scale at the 24th hour, and quality of
life was measured using the OHIP 14 scale at the 24th hour, and at the 3rd, 6th, and 12th
months. For statistical analysis, the Mann Whitney U test was used, along with
Bonf erroni and Tukey post hoc tests ( p ≤
Results: No significant difference was found between the groups in terms of mean
age ( p =0.881) and gender distribution p =1.000). There was also no significant
association between gender and patient quali ty of life. No statistically significant
difference was observed between the groups regarding 24 hour postoperative pain with
VAS scores ( p =0.312). However, statistically significant differences were found in
psychological discomfort and OHIP scores at the 24th hour, indicating that the OR group
experienced more psychological distress than the OC group on the first day. The
relationship in scores between the 24th hour and the 12th month at OR group was
significantly greater than at OC group ( p =
Conclusion: The O C and O R systems showed similar effects on quality of life at
3, 6, and 12 months postoperatively. However, O C was more comfortable than O R in
V
terms of psychological discomfort experienced on the first day. Due to the higher initial
terms of psychological discomfort experienced on the first day. Due to the higher initial OHIP score in the OOHIP score in the ORR group, the change in OHIP scores from day one to 12 months was group, the change in OHIP scores from day one to 12 months was greater than that observed in the Ogreater than that observed in the OCC group. group. We can conclude that the change in OHIP We can conclude that the change in OHIP scores in both test groups is primarily due to the different instrumentation techniques.scores in both test groups is primarily due to the different instrumentation techniques