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Validity and reliability of the Turkish version of the Innsbruck RBD-9 diagnostic inventory (IRBD-9-TR)
No full textBackground Isolated rapid eye movement (REM) sleep behavior disorder (iRBD) is characterized by loss of the normal atonia of REM sleep accompanied by repetitive motor and behavior phenomena of dream content. Objective To evaluate the reliability and validity of the Turkish version of the original form of the Innsbruck Rapid Eye Movement Sleep Behavior Disorder Diagnostic Inventory (IRBD-9) scale (IRBD-9-TR) and ensure that this screening test can be easily used in the Turkish language. Methods The present is a multicenter and prospective study involving 184 patients: 51 with iRBD and 133 healthy controls. The iRBD patients were not diagnosed before submitted to video polysomnography (vPSG) and filling out the IRBD-9-TR. Results The optimal cut-off value for the IRBD-9-TR symptom score was of 0.28, with a sensitivity of 0.941 and a specificity of 0.947, and 94.4% of the patients were correctly diagnosed. The rotated factor loadings for the diagnostic accuracy of each individual question showed that the short version of the IRBD-9-TR (questions 1, 2, 3, 6, and 8) presented higher specificity and excellent discrimination of iRBD patients from healthy controls. The Cronbach's alpha coefficient for the symptom section of the IRBD-9-TR was of 0.857, and the Kappa coefficient, of 0.885. Conclusion The short version of the IRBD-9-TR presents good validity and reliability to be used as a screening test to assess iRBD patients. It is convenient and potentially useful in both outpatient clinical and epidemiologic research settings
Therapeutic neuroscience education in fibromyalgia: a randomized controlled trial
No full textObjective To investigate additive effect of Therapeutic Neuroscience Education (TNE) to pilates exercises in female patients with fibromyalgia (FM). Method 25 female patients FM included in the study. They randomly separated into two groups. There were 11 patients in the intervention group and 14 patients in the control group. Pilates exercises and TNE were applied in the intervention group, and only pilates exercises were applied in the control group. Dynamic Loewenstein Occupational Therapy Cognitive Assessment (DLOTCA), Visual Analogue Scale (VAS), Brief Pain Inventory (BPI), Widespread Pain Index (WPI), Fibromyalgia Impact Questionnare (FIQ), Symptom Severity Scale (SSS), Pain Catastrophizing Scale (PCS), Tampa Scale for Kinesiophobia (TSK), Biopsychosocial Questionnaire (BETY-BQ) and pressure algometer was used for evaluation. Results After the treatment, control group improved in the "visuomotor construction" and "thinking operations"cognitive areas andtotal score of DLOTCA, BPI-pain severity score, VAS, FIQ, SSS, PCS-magnification, and only left medial knee mean score of pressure pain thresholds (p0.05). Intervention group improved in the "thinking operations" cognitive area and total score of DLOTCA, BPI-pain severity score, BPI-pain interference score, VAS, WPI, FIQ, SSS, TSK, BETY-BQ and all pressure pain thresholds (excluding left trapezius) (p0.05). In the comparison of delta values, the intervention group improved more in WPI, FIQ, right trapezius mean score and left trapezius, right quadriceps femoris, right-left medial knee maximum and mean scores of pressure pain thresholds (p0.05). Conclusion TNE increased the effectiveness of pilates exercises on pain, functional status and pressure pain thresholds in patients with FM.Pamukkale University Scientific Research Projects Coordination Unit [2019SABE010]This study was supported by Pamukkale University Scientific Research Projects Coordination Unit (Project No: 2019SABE010)
Fluvoxamine inhibited nlrp3 and nf-κb inflammatory pathways and maintained genital functions by ameliorating cd-mpr, kiss-1, aqp4 and claudin-1 expressions
No full textFluvoxamine (FLV), a selective serotonin reuptake inhibitor, is commonly used to treat anxiety, major depressive disorder and obsessive-compulsive disorder, among other psychiatric conditions. This study aims to evaluate the effectiveness of FLV in mitigating damage caused by lipopolysaccharide (LPS) to the female genital tract. Thirty-two female Wistar Albino rats were randomly divided into four groups: control, LPS, LPS-FLV and FLV. At the end of the experimental period, tissues from the ovaries, fallopian tubes and uterus were collected for histological, immunohistochemical and genetic analyses. Histological examination of the LPS group revealed mild to moderate bleeding, oedema and neutrophil infiltration. Additionally, there were signs of endometrial damage in the uterus and loss of cilia in the fallopian tubes. Immunohistochemical analysis showed that LPS increased the expressions of nuclear factor kappa beta (NF-kappa B) and cation-dependent mannose 6-phosphate receptors (CD-MPR) and reduced kisspeptin-1 (KISS-1) expression. Genetic analysis indicated that LPS increased the expression of the NOD-like receptor family pyrin domain-containing 3 (NLRP3) and aquaporin4 (AQP4) genes while decreasing Claudin-1 expression. However, all these adverse effects were reversed by FLV treatment. The study's findings suggest that FLV may be beneficial in treating LPS-induced damage to the female reproductive system.Suleyman Demirel University [TSG-2023-9010]; Scientific Research Projects Coordination Unit of Suleyman Demirel UniversityHereby, we would like to thank the Scientific Research Projects Coordination Unit of Suleyman Demirel University, with the project code TSG-2023-9010
Erken çocuklukta dini simge ve ritüellerin psikososyal gelişim üzerindeki rolü
No full textBu çalışma, erken çocukluk döneminde dini semboller ve ritüellerin çocukların psikososyal
gelişimi üzerindeki etkilerini akademik bir perspektifle incelemektedir. Erken çocukluk
dönemi, kimlik inşası, duygusal düzenleme mekanizmalarının gelişimi ve sosyal etkileşim
becerilerinin şekillenmesi açısından kritik bir evredir. Dini semboller ve ritüeller, kültürel ve
manevi bileşenler olarak, çocukların değer sistemlerini, ahlaki algılarını ve dünyaya yönelik
bilişsel çerçevelerini biçimlendirmede belirleyici bir rol oynayabilmektedir. Bu araştırma,
çocukların bu uygulamalara maruz kalma ve aktif katılım süreçlerinin aidiyet duygusu,
duygusal güvenlik ve sosyal davranışlar üzerindeki etkilerini değerlendirmektedir. Çalışma,
gelişim psikolojisi, sosyoloji ve din bilimleri disiplinlerini bir araya getirerek, bütüncül bir
analiz sunmayı hedeflemektedir. Araştırma bulguları, empati, iş birliği ve anlam duygusu
geliştirme gibi olumlu sonuçların yanı sıra, dışlanma veya bilişsel çatışma risklerine de dikkat
çekmektedir. Bu bağlamda çalışma, dini pratiklerin erken çocukluk döneminde bütüncül
gelişim süreçlerini destekleme potansiyeline ilişkin akademik literatüre katkı sunmayı
amaçlamaktadır.This study examines the impact of religious symbols and rituals on the psychosocial
development of children in early childhood from an academic perspective. Early childhood is
a critical period for identity formation, the development of emotional regulation mechanisms,
and the shaping of social interaction skills. Religious symbols and rituals, as cultural and
spiritual components, can play a significant role in shaping children's value systems, moral
perceptions, and cognitive frameworks of the world. This research evaluates the effects of
children’s exposure to and active participation in these practices on their sense of belonging,
emotional security, and social behaviors. The study aims to present a holistic analysis by
integrating the disciplines of developmental psychology, sociology, and religious studies. The
research findings highlight positive outcomes, such as fostering empathy, cooperation, and a
sense of purpose, while also drawing attention to the risks of exclusion or cognitive conflict.
In this context, the study seeks to contribute to the academic literature on the potential of
religious practices to support holistic developmental processes in early childhood
Towards sustainable combustion: A comprehensive exergoeconomic and exergoenvironmental analysis with LCA integration for an RCCI engine
No full textThis research focuses on the environmental and economic investigation of different intake air temperatures (IATs), engine speeds and amount of injected fuel in an internal combustion engine (ICE) operating with RCCI combustion mode. These exergoenvironmental and exergoeconomic analyses were carried out using data from energy and exergy analyses for an RCCI engine fueled with n-heptane and isopropanol. The study aims to evaluate the economic and environmental effects of the engine in detail. The cost of power from the engine shaft was calculated as 6.13/MJ and 67.12/h at engine speed of 2500 rpm, IAT of 30 degrees C and a total amount of fuel injected of 20 mg/cycle. The environmental impact of exergy losses was calculated as 266.88 mPts/GJ based on these parameters. The results show that the optimum values for the cost and environmental impact of power from the engine shaft were obtained at an engine speed of 2000 rpm. These findings highlight the importance of optimizing air temperatures and fuel injection parameters to improve both economic and environmental performance. The assessment of economic and environmental impacts under different operating conditions is an innovative aspect of the study
Exploring the Dual Role of Bivo4 Nanoparticles: Unveiling Enhanced Antimicrobial Efficacy and Photocatalytic Performance
No full textThis study was focused on enhancing the structural, optical, antimicrobial, and photocatalytic activities of bismuth vanadate (BiVO4) nanoparticles. The current study utilized a simple hydrothermal technique to fabricate BiVO4 nanoparticles. Several techniques, including X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Raman, Field emission scanning electron microscopy (FESEM), energy dispersive spectroscopy (EDS), and ultraviolet-visible (UV-Vis), were used to examine BiVO4. The monoclinic structure of BiVO4 was confirmed through XRD, XPS, and Raman analysis, validating its high purity and the absence of secondary phases with a size of 31 nm. The decahedral structure and purity of BiVO4 were revealed through FESEM-EDS microstructure and surface morphology examination. A band gap of 2.36 eV was exhibited by the synthesized BiVO4 nanoparticles. The conduction band minimum and valence band maximum edge potentials were found to be 2.715 eV and 0.355 eV, respectively. The antimicrobial properties of BiVO4 NPs were evaluated using the disc diffusion method on a broad spectrum of pathogens. Various bacterial and fungal pathogens showed broad-spectrum antimicrobial activity against BiVO4, indicating that BiVO4 nanoparticles (NPs) could be effective antimicrobial agents. In addition, the photocatalytic performance of BiVO4 and its degradation efficiency were investigated with Oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) antibiotics under visible light. The photocatalytic degradation results demonstrated that BiVO4 successfully degraded the antibiotic residuals. The results showed that the hydrothermally synthesized BiVO4 nanoparticles have great potential for use in biological and environmental applications. © The Author(s) 2025.Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTA
Kırsal mahalle belirlenmesinde bir yöntem önerisi: Pamukkale ilçesi örneği
No full text6360 sayılı Yasa sonrası büyükşehir belediyesi sınırları içinde kalan köy ve belde belediyelerinin mahalleye dönüşmüş kır, kentin içinde kaybolmuştur. Daha sonra, 2020 yılında Büyükşehir Belediyesi Kanununda değişiklik yapılarak Kırsal Mahalle kavramı mevzuata yerleştirilmiştir. Ardından uygulamayı tarif etmeye yönelik Kırsal Mahalle ve Kırsal Yerleşik Alan Yönetmeliği yayınlanmıştır. Tez araştırması kapsamında da söz konusu Yönetmelik çerçevesinde büyükşehir belediyesi sınırları içindeki kırsalın tespit edilmesi için bir yöntem geliştirilmesi amaçlanmıştır. ikinci bölümde kırsal kavramı ile mevzuatı, üçüncü bölümde ise Yönetmelik sonrası büyükşehir belediyelerinin kırsala ilişkin tutumlarını ve ihtiyaçlarını ortaya koyan ilgili meclis kararları incelenmiştir. Son bölümde seçilen örnek alanda, önerilen yöntemin uygulaması yapılmıştır.
Tez kapsamında, kırsalın tespitine ilişkin meclis kararı bulunmayan 4 büyükşehir belediyesinden Denizli Büyükşehir Belediyesi sınırları içindeki en büyük nüfuslu ilçe olan Pamukkale ilçesi örnek alan seçilmiştir. Öncelikle kırsal kapsamında ele alınacak mahalleler belirlenmiş, sonrasında Yönetmelik çerçevesinde ana başlıklar ve buna bağlı sayısallaştırılmış gösterge seti oluşturulmuştur. Puanı arttıkça kırsallığı artacak şekilde 100 puan üzerinden değerlendirme tablosu oluşturulup mahallelerin kırsallık dereceleri ortaya konmuştur. Tablolar kıyas yapmayı sağlayacak şekilde haritalarla birlikte ele alınmıştır. Sonuç olarak belediyelerin kendi vizyonları çerçevesince yorumlamasına olanak sağlayan tablo ve haritalar elde edilmiştir. Araştırma bulguları ile kırsal olduğu öngörülen mahallelerin kırsallık derecelerinin de yüksek çıktığı ancak tartışmalı olabilecek mahallelerin kendi bölgeleri içinde parçalı bir yapı ortaya koyduğu görülmüştür. Yapılan çalışma ile kırsal sınırların belirlenmesinin tek başına yeterli olmadığı onaylı imar planlarında yapılacak değişikliklerle desteklenmesi ve alana özgü diğer verilerle birlikte yorumlanması gerektiği sonucu ortaya çıkmıştır.Within the borders of metropolitan municipalities villages and town municipalities turned into neighborhoods and the countryside was lost within the city after Law No. 6360. Later, in 2020, the Metropolitan Municipality Law was amended and the concept of Rural Neighborhood was included in the legislation. Then, the Rural Neighborhood and Rural Settlement Area Regulation was published to describe the application. In the thesis research, it was aimed to develop a method for determining the rural area within the borders of metropolitan municipalities in accordance with the Regulation. In the second section, the concept of rural area and its legislation were examined. In the third section, the relevant council decisions that reveal the attitudes and needs of metropolitan municipalities regarding rural areas after the Regulation were examined. In the last section, the application of the proposed method was made in the selected sample area.
There is no council decision regarding the determination of rural areas in 4 metropolitan municipalities. Denizli Metropolitan Municipality is one of these municipalities. Pamukkale District, which is the district with the highest population density within the borders of Denizli Province, was also selected as a sample area for the thesis research. First, the neighborhoods to be evaluated within the scope of rural were determined. Then, the main headings and the relevant numerical indicator set were created within the framework of the Regulation. As a result, an evaluation table was created out of 100 points, which determined the rurality levels of the neighborhoods. The points were adjusted to increase as rurality increased. Tables were considered together with maps in a way that would allow comparison. The resulting tables and maps were designed in a way that municipalities could interpret within the framework of their own visions. The research findings showed that the rurality degrees of the neighborhoods predicted to be rural were also high, but the neighborhoods that could be controversial presented a fragmented structure within their own regions. The study concluded that determining rural boundaries alone is not sufficient. Results should be supported by changes to be made in approved zoning plans and interpreted together with other area-specific data
A note on generalized k-order F&l hybrinomials
No full textIn this study, we introduce generalized k-order Fibonacci and Lucas (F;L) polynomials that allow the derivation of well-known polynomial and integer sequences such as the sequences of k-order Pell polynomials, k-order Jacobsthal polynomials and k-order Jacobsthal F;L numbers. Within the scope of this research, a generalization of hybrid polynomials is given by moving them to the k-order. Hybrid polynomials defined by this generalization are called k-order F;L hybrinomials. A key aspect of our research is the establishment of the recurrence relations for generalized k-order F;L hybrinomials. After we give the recurrence relations for these hybrinomials, we obtain the generating functions of hybrinomials, shedding light on some of their important properties. Finally, we introduce the matrix representations of the generalized k-order F;L hybrinomials and give some properties of the matrix representations
Beklentiler ve sonuçları açısından hac olayı (Denizli örneği)
No full textDin toplumun temel kurumlarından biridir, toplum ile din arasında güçlü bir ilişki bulunmaktadır. Din toplumsal değişim sürecinde etkili bir unsurdur. Bireylerin ve ailelerin huzurunu temin eden, toplumsal barış ve mutluluğu destekleyen bir yapı sunar. Din inananlarına bir dünya görüşü ve yaşam biçimi sunarak, hayatın şekillenmesinde sürekli bir rol oynar. Aynı zamanda, insanları rahatsız eden olumsuzlukları ve kötülükleri uzaklaştırıp hak, adalet, merhamet ve şefkat gibi değerlerin bireylerin vicdanlarında ve davranışlarında yerleşmesini teşvik eder. Din bazen toplumsal değişimlere direnç göstererek istikrarı sağlar ve toplumun birliğini, düzenini korur. Bu bağlamda, dinin toplum yaşamında çeşitli işlevleri bulunmaktadır. Bu işlevlerin hayata geçirilmesinde dinin pratikleri olan ibadetlerin önemli bir rolü vardır. İbadetler, Allah’a teslimiyet, kardeşlik ve dayanışma gibi değerleri güçlendiren bir zeminde, bireylerin ahlaki olgunluğa ulaşmasını sağlar ve toplumsal normlara uyumu destekler. İslam’ın temel ibadetlerinden biri olan hac, bireysel değişim sağlama özelliğinin yanında toplumsal bir boyut da taşır. Hac, inançlı bireyleri aynı amaç doğrultusunda bir araya getirerek iletişim ve etkileşim içinde kolektif bir bilinç oluşmasına katkı sunan evrensel bir olaydır. Bu yönüyle hac, evrensel bir nitelik sergiler ve yalnızca dini bir ritüel olmanın ötesine geçerek bireysel ve toplumsal yansımaları olan bir olguya dönüşür. Hac ibadetinin bireylerin kişilik, duygu, düşünce, alışkanlık ve davranışları üzerindeki etkilerini incelemek ve sosyolojik açıdan bunları değerlendirmek bu çalışmanın ana amacını oluşturmaktadır.Religion is one of the fundamental institutions of society, and there is a strong relationship between society and religion. Religion is an effective element in the process of social change. It provides a structure that ensures the peace of individuals and families, and supports social peace and happiness. Religion plays a constant role in shaping life by offering its believers a worldview and lifestyle. At the same time, it removes the negativities and evil that disturb people and encourages values such as rights, justice, mercy and compassion to be established in individuals' consciences and behaviors. Religion sometimes provides stability by resisting social changes and protects the unity and order of society. In this context, religion has various functions in social life. The practices of religion, which include worship, play an important role in the implementation of these functions. Worship enables individuals to reach moral maturity on a basis that strengthens values such as submission to Allah, brotherhood and solidarity, and supports compliance with social norms. Hajj, one of the fundamental worships of Islam, has a social dimension in addition to its feature of providing individual change. Hajj is a universal event that brings together believers for the same purpose and contributes to the formation of a collective consciousness through communication and interaction. In many belief systems, sacred places and temples are seen to have a special meaning for believers. In this respect, Hajj exhibits a universal quality and goes beyond being a mere religious ritual and becomes a phenomenon with individual and social reflections.The main purpose of this study is to examine the effects of Hajj on individuals' personalities, emotions, thoughts, habits and behaviors and to evaluate them from a sociological perspective
Manevi destek ve rehberlikte iletişimin önemi
No full textThis research on the importance of communication in spiritual support and guidance
aims to examine the role of effective communication in the processes of protecting and
developing the spiritual and emotional health of individuals. Elements of communication such
as empathic, open, honest and active listening allow clients to express themselves better, feel
trust and receive emotional support during the spiritual guidance process. The importance of
the research is to reveal how spiritual guidance services can be made more efficient by using
effective communication strategies and how individuals can increase their quality of life. The
results obtained show that empathic listening plays a critical role in understanding the
emotional needs of clients, open and direct communication reinforces trust and regular
feedback improves the psychological well-being of clients. In addition, it was determined that
cultural sensitivity and flexible communication strategies make clients feel more comfortable
and understood. This research provides important findings on how spiritual guides can
support the spiritual health and general well-being of their clients by developing effective
communication skills.Manevi destek ve rehberlikte iletişimin önemi üzerine yapılan bu araştırma, bireylerin
ruhsal ve duygusal sağlığını koruma ve geliştirme süreçlerinde etkili iletişimin rolünü
incelemeyi amaçlamaktadır. İletişimin empatik, açık, dürüst ve aktif dinleme gibi unsurları,
manevi rehberlik sürecinde danışanların kendilerini daha iyi ifade etmelerine, güven
duymalarına ve duygusal destek almalarına olanak tanımaktadır. Araştırmanın önemi, manevi
rehberlik hizmetlerinin etkili iletişim stratejileri kullanılarak nasıl daha verimli hale
getirilebileceğini ve bireylerin yaşam kalitesini nasıl artırabileceğini ortaya koymaktır. Elde
edilen sonuçlar, empatik dinlemenin danışanların duygusal ihtiyaçlarını anlamada kritik bir
rol oynadığını, açık ve doğrudan iletişimin güveni pekiştirdiğini ve düzenli geri bildirimin
danışanların psikolojik iyilik hallerini geliştirdiğini göstermektedir. Ayrıca, kültürel duyarlılık
ve esnek iletişim stratejilerinin, danışanların kendilerini daha rahat ve anlaşılmış
hissetmelerini sağladığı belirlenmiştir. Bu araştırma, manevi rehberlerin etkili iletişim
becerileri geliştirerek, danışanlarının manevi sağlıklarını ve genel iyilik hallerini nasıl
destekleyebileceklerine dair önemli bulgular sunmaktadır