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Yttrium phosphate microspheres with enriched phosphorus content prepared for radiotherapy of deep-seated cancer
Get PDFCeramic microspheres composed of β-emitters are useful for in situ radiotherapy of deep-seated cancer by implantation around the tumor. In addition, microspheres 20–30 µm in diameter can combine β-emission with the embolization effect. Yttrium phosphate is an attractive candidate material for such microspheres, because both Y and P play roles as β-emitters. The half-life of 31P is known to be much larger than that of 90Y. Therefore, it is expected that yttrium phosphate microspheres with high P content can maintain a longer radiotherapy effect. In the present study, preparation of microspheres with enriched P content has been attempted by water-in-oil emulsions using polyphosphate as a starting material. Yttrium phosphate microspheres with a higher P/Y molar ratio (2.5) than in previously reported YPO4 microspheres were obtained. It was found that emulsification for sufficient time (more than 10 min) is necessary to obtain microspheres that are 20–30 µm in size. Although the microspheres released Y sparingly, they released larger amounts of P than previously reported YPO4 microspheres in a simulated body environment. Heat treatment at moderate temperature can suppress P release to some extent. Further improvement in chemical durability through surface modification is essential for long-term clinical use
Ultrafast Lateral 600 V Silicon SOI PiN Diode with Geometric Traps for Preventing Waveform Oscillation
Get PDFAn ultrafast lateral silicon PiN diode with traps is proposed using a silicon-on-insulator (SOI) substrate with traps. The proposed diode successfully suppresses waveform oscillation because the trapped hole suppresses electric field penetration and prevents the oscillation trigger known as “dynamic punch-through.” Because of the short current path caused by the oscillation prevention, the reverse recovery speed was higher and the reverse recovery loss was strongly reduced. The proposed trap structure and design method would contribute to performance improvement of all power semiconductor devices including IGBTs and power MOSFETs
Rolling contact fatigue simulation used for full-open type greenhouse
Get PDFThe green house is often used to add the quality and value of agricultural products. Newly developed full open type green house has a lot of attracted attention whose roof opens and closes automatically in order to control the temperature. However, since the roof opens and closes very often, the cover sheet can be used only for 3-4 months. This is because the plastic film is damaged between the support pipe and rolling pipe during opening-closing affected by fatigue and wear. In this study, the damage mechanism is investigated for the several plastic films used for the full open type green house. In the first place, FEM analysis is performed to evaluate the damage of plastic film between pipes under different film materials. Here, the maximum contact pressure and thickness reduction are analysed under static contact analysis and rolling contact analysis as the most important factors. Finally, rolling fatigue experiment is performed to investigate the damage with changing plastic films. Then, the results are compared with the FEM analysis
末梢および中枢神経系における情報調節機構の研究：味神経線維興奮性の味物質受容体依存性およびストレス刺激受容における脳内セロトニン1A受容体の役割
Get PDF九州工業大学博士学位論文 学位記番号:生工博甲第228号 学位授与年月日:平成26年9月26日1. 緒言||2. 味神経線維興奮性の味物質受容体依存性||3. ストレス刺激受容における脳内セロトニン1A受容体の役割||4. 総論||5. 謝辞||6. 参考文
Study on a Method for Evaluation of Real Estate Fund:Preliminary Study on Application to Real Option
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母集団を動的に分割統合する遺伝的アルゴリズムの提案とその応用によるリアルタイム最適軌道生成
Get PDF九州工業大学博士学位論文（要旨） 学位記番号:工博甲第360号 学位授与年月日:平成26年3月25
分子選択的結合性に着目した非天然アミノ酸の抗体及びトリプシン様酵素との相互作用に関する研究
Get PDF九州工業大学博士学位論文 学位記番号:生工博甲第213号 学位授与年月日:平成26年3月25日第1章 序論||第2章 天疱瘡自己抗体を吸着する天然・非天然アミノ酸を基にしたリガンドのスクリーニング||第3章 チエニルアミノ酸をリガンドとするフィブリノーゲン吸着を抑制した選択的IgG、IgM抗体の吸着材||第4章 パラグアニジノフェニルアミノ酸誘導体とStreptomyces griseusトリプシンとの相互作用||第5章 エールリッヒ腹水癌移植マウス腹水中のパラグアニジノフェニルアラニンに特異的な新しいセリンプロテアーゼ||第6章 結