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Seroprevalence of rinderpest in non-vaccinated cattle in Unity State, Southern Sudan
No full textarticle pages7In the frame work of the Pan African Control of Epizootics (PACE) Program, a cross-sectional serological survey for rinderpest (RP) was conducted among non-vaccinated cattle in Unity State, Sudan. A total of 280 serum samples were collected from cattle of different ages and both sexes in eight sites between June and December 2004. These sera were tested for antibodies against rinderpest virus (RPV) using a competitive enzyme-linked immunosorbent assay (c-ELISA). Only . % of the sera were positive to the RPV antibodies in the different locations of the state. An obvious and significant (p<0.05) variation in the prevalence of antibodies to the virus among various locations was noted. A significantly (p <0.01) higher levels of prevalence rates were observed in the age group of 5 to 10 years of cattle compared to other age groups. The results also indicated the prevalence of antibodies to the virus in females is always higher than in the male animals (p<0.05). Our data demonstrated the situation of RP in the unity state, the only locus known to harbor the disease in the country at large. This helped by designing a strategic eradication plan leading to declare Sudan as a RP free country in 2005
Glomerulonephritis: a Histopathological Study in Sudanese Children in Khartoum State (2008 – 2010)
No full textBackground: Glomerulonephritis (GN) is one of the most common
cause of end stage renal disease (ESRD) and chronic renal failure in
Sudan. The aim of the study is to determine the histopathological patterns
of GN based on renal biopsy, in relation to demographic data and risk
factors with verification of the clinical outcome.
Methods: This is a descriptive case series study of 150 patients with
glomerulonephritis from January 2008 to December 2010. It was
conducted in Soba University Hospital and Fedail Hospital. Patient’s
data was collected using predesigned questionnaire. Formalin fixed
paraffin embedded blocks of processed specimens were recut, stained
using Hematoxylin and Eosin, PAS, Masson Trichrome and silver stains
and then reviewed. SPSS program version 10 was used in the analysis.
Results: The patient’s ages ranged between 3 month to 18 years with a
mean age of 10.25 ± 4.5 SD.The male to female ratio is 1.00: 1.11.The
majority of cases (43%) were from Northern Sudan. The commonest
pattern of GN was diffuse mesangioproliferative GN (16.7%).Risk factors
were statistically correlated with the patterns of GN (P.value =0.000).
90.7% of cases received steroids therapy and 16% received chemotherapy
.Few cases developed complications, such as acute renal failure (4%)
,while chronic GN and chronic renal failure in (0.7%).
Conclusion: The age, sex, clinical presentation and the patterns of GN in
Sudan were comparable to other studies Few cases had complications
such as chronic renal failure which was high in studies done in Egypt and
USA, where GN is the leading cause of chronic GN and ESRD. The
majority had good response to corticosteroids
