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L’architettura del quartiere: quattro modi di pensare l’insediamento extra-urbano
No full textIl Programma Straordinario per l’Edilizia Residenziale, varato dopo il terremoto dell’Irpinia del 1980, rientra a pieno titolo nell’elenco
delle molte vicende che, oltre le avanguardie e il dopoguerra, hanno offerto agli architetti occasioni collettive “eccezionali” per mettere alla prova la cultura del progetto. E questa prova in particolare può essere considerata, a distanza di quarantacinque anni, una cartina al tornasole delle teorie progettuali che andavano addensandosi in Italia, già da un decennio, intorno a una sensibile interpretazione dell’architettura della città e del rapporto dialogico (e spesso controverso) tra centro e periferia. La complessa vicenda del PSER extra-urbano – con un repertorio di ben diciannove diversi quartieri realizzati nell’allora “provincia” di Napoli, in luoghi geograficamente e morfologicamente molto diversi tra loro – è infatti da sola capace di offrire un affresco delle molte modalità attraverso le quali può costruirsi l’"architettura del quartiere", rivelando oggi limiti e potenzialità di alcune precise posture teorico-progettuali. È dentro questa cornice che prende corpo la selezione di quattro approfondimenti, votati a mettere in rilievo i casi in cui le ragioni del progetto appaiono chiaramente espresse nel rapporto che sussiste tra l’impianto insediativo e il paesaggio, tra le scelte tipologiche e la costruzione dello spazio collettivo, tra i caratteri dell’architettura e il suo significato civico. Afragola (Rione Salicelle), Boscoreale Villa Regina, Boscoreale Passanti e Quarto, in particolare, sono i quattro casi-studio oggetto di una specifica indagine tipo-morfologica condotta attraverso lo strumento del ridisegno
Componente della Scuola dottorale in Filosofia, sezione Filosofia del diritto, della Facoltà di Lettere del Centro Universitarii Nord di Baia Mare dell’Università Tecnicâ di Cluj Napoca (Romania).
No full textHousing for migrants. Naples as an inclusive city
No full textThe article provides a summary of research on the reception of foreigners in Campania, particularly in Naples, whit regard to housing and collective spaces. More than half of the foreigners living in the Campania region (129,453; 51.3%) reside in Naples. The data reveal an urban territory that is predominantly inhabited from third countries and has a problematic recep-tion spaces situation that hinders social integration. Most live in groups of three or four in uninhabited houses rented from private individuals and dispersed throughout the province, frequently in its periphery. In the re-search, the city of Napoli is used as a laboratory for experimenting with an “autonomous” housing unit as suggested by the Action Plan for Integration and Inclusion 2021–2027, promoted by the European Commission, which, in defining measures to build more cohesive and inclusive societies for all, places the issue of housing and settlements for migrants within a broader series of actions to implement the Plan.
Specifically, the survey focuses on North African migrants, especially those from Morocco, who (according to ISTAT 2022 data) rank third in the region after Ukraine and Romania. In addition to the housing crisis, the question of multireligion as a migration issue was also included in the survey, which led to the decision to focus the research on Moroccan immigrants. Therefore, affiliation with a particular religious matrix was also considered in the re-search, as this is a determining factor of the reference culture. The Islamic faith practised by Moroccan immigrants draws attention to the issue of places of worship and, consequently, the construction of mosques for the purposes of greater integration.
The research focusing on the Italian reception and integration system (SAI) proposes settlements for migrants in certain areas of the city of Naples where residences are in close proximity to both production and work spac-es as well as collective spaces capable of holding together the scale of archi-tecture and that of the city in order to build a close relationship between migrants and local inhabitants
Diritti e principi digitali dell’Unione europea
No full textIl mercato unico digitale tra antichi problemi e nuove sfide: una guida agli strumenti fondamentali di diritto dell'Unione europe
Colorimetric sensing for transdermal phospho-Tau 181 detection mediated by wearable microneedle functionalized with gold nanoparticle (MN-AuNP)
No full textMicroneedles (MNs) have rapidly emerged as powerful tools in wearable biosensing, providing minimally invasive access to interstitial fluid (ISF). Among the neurodegenerative based biomarkers detectable in ISF, phosphorylated Tau at threonine 181 (p-Tau181) is reaching a clinically evaluable significance for Alzheimer's disease (AD) and other tauopathies. Elevated p-Tau181 levels are strongly correlated with abnormal Tau aggregation in the brain and with cognitive decline. Current diagnostic methods rely on invasive cerebrospinal fluid (CSF) sampling or costly laboratory immunoassays and radio-imaging which are unsuitable for routine or point-of-care screening. Here, we present a highly sensitive colorimetric microneedle-based immunosensor designed for non-invasive, transdermal detection of p-Tau181. For the first time, gold nanoparticles (AuNPs) are integrated into a three-dimensional (3D) microneedle geometry, where antibody antigen recognition occurs directly on MN in contact with ISF. The aggregation-induced optical shifts of AuNPs provide an immediate and instrument-free colorimetric signal, while two optimized coating techniques enable uniform immobilization and reproducible performance. The MN-AuNP platform achieves a limit of detection (LoD) of 16 pg/mL, a nearly 30-fold improvement compared to the reported 2D surface (460 pg/mL). This enhancement shoots from the 3D architecture, which offers greater surface area, enhanced probe loading, and improved analyte diffusion. Compared with existing diagnostic approaches, the proposed system offers multiple advantages: non-invasive operation, real-time readout without complex instrumentation, low fabrication cost, and potential integration into wearable or point-of-care formats. Collectively, these results lay the groundwork for advanced MN-based colorimetric biosensors for early Alzheimer's disease detection through accessible and patient-friendly neurodiagnostic technologies
Torque fault signal extraction in hybrid electric powertrains through a wavelet-supported processing of residuals
No full textMultifunctional biosensors redefining liquid biopsy: advancing simultaneous multianalyte detection
No full textLiquid biopsy has revolutionized noninvasive disease diagnosis and monitoring by detecting circulating biomarkers such as tumor-derived DNA, miRNAs, proteins, exosomes, and circulating tumor cells in body fluids. Conventional single-analyte approaches fail to capture disease complexity, limiting diagnostic accuracy. Multifunctional biosensors enable simultaneous detection of multiple biomarkers, representing a paradigm shift in liquid biopsy. This review highlights recent advances in diverse detection strategies, including optical, electrochemical, plasmonic, and clustered regularly interspaced short palindromic repeats–based assays, alongside innovations in hybrid platforms, smart surface engineering, and nanotechnology. We also discuss integration with microfluidics, artificial intelligence, and chemometric analysis to enhance sensitivity, reduce signal interference, and improve scalability. Finally, challenges in clinical translation and standardization are highlighted, underscoring the transformative potential of multifunctional biosensors in precision medicine and early disease detection