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Evaluation of Atherosclerotic Risk by Oxidative Contributors in Alcohol Use Disorder
Get PDFObjective: Alcohol Use Disorder (AUD) is a condition described as the inability to control or stop alcohol consumption. The patients with AUD have an increased risk of developing atherosclerosis-related diseases. The present study aimed to evaluate oxidative contributors of atherosclerotic risk factors in patients with AUD.Methods: The male subjects diagnosed with AUD (n = 45) and the male subjects as control (n = 35) were enrolled in this study. All participants were undergone psychiatric evaluation and sociodemographic tests. Also, serum oxidative contributors of atherosclerosis including myeloperoxidase (MPO), ferroxidase, catalase (CAT), and lipid hydroperoxides (LOOH) were measured. Additionally, serum lipid profile tests and atherogenic indicators including atherogenic index of plasma (AIP) and non-high-density lipoprotein (HDL) cholesterol were also analyzed.Results: The AUD subject had significantly elevated MPO activity and LOOH levels with decreased antioxidant capacity. AIP and non-HDL cholesterol levels, the atherogenic indicators, were also higher in AUD group compared to the control group. We found the MPO activity and LOOH levels were positively correlated with AIP, non-HDL cholesterol levels, and amount of alcohol consumption. Additionally, CAT activity was negatively correlated with duration of alcohol consumption. Conclusion: Our results revealed that MPO and LOOH levels were elevated by severe alcohol intake and the athero-genic indicators, AIP and non-HDL cholesterol, were significantly correlated alcohol induced elevated oxidative risk factors. Therefore, it can be suggested that MPO activity and LOOH levels may be useful to determine jeopardy of atherosclerotic and the therapeutic interventions that reduce oxidative load could be taken into account to prevent atherosclerotic diseases before clinical manifestation
Institutional Quality and Geography of Discontent in the EU
No full textThere has been a significant rise in anti-establishment votes in the European Union (EU). The decline in socio-economic outcomes and migration played an important role in understanding the rising discontent. However, none of the existing studies analysed the effect of socio-economic factors in different institutional settings. Our findings confirm that institutional quality is of paramount importance in explaining the recent rise in populism in the EU, as institutionally developed EU regions are less opposed to EU integration. Remarkably, the effects of socio-economic factors on populist votes vary in different institutional settings. The findings highlight that institutional improvements are vital for the EU perception of less developed and socio-economically isolated EU regions
Search for CP violation using (Formula presented.) events in the lepton+jets channel in pp collisions at ?s = 13 TeV
Get PDFResults are presented on a search for CP violation in the production and decay of top quark-antiquark pairs in the lepton+jets channel. The search is based on data from proton-proton collisions at s = 13 TeV, collected with the CMS detector, corresponding to an integrated luminosity of 138 fb?1. Possible CP violation effects are evaluated by measuring asymmetries in observables constructed from linearly independent four-momentum vectors of the final-state particles. The dimensionless chromoelectric dipole moment of the top quark obtained from the observed asymmetries is measured to be 0.04 ± 0.10 (stat) ± 0.07(syst), and the asymmetries exhibit no evidence for CP-violating effects, consistent with expectations from the standard model. [Figure not available: see fulltext.]. © 2023, The Author(s)
Investigating the implications of virtual reality and augmented reality in tourism marketing: A systematic literature review of publications from 2010 to 2023
No full textThis literature review aims to investigate the developments of virtual reality (VR) and augmented reality (AR) research in tourism marketing. This chapter also highlights fruitful directions for tourism marketing research regarding VR and AR applications. A total of 31 full-length articles published between 2010 to 2023 were retrieved from the Web of Science database and reviewed. The theoretical backgrounds of the articles were thoroughly examined, and a detailed report on the research progress of the theories and research methodologies are presented. Finally, future research directions for the improvement of the existing literature are explained. © 2023 by IGI Global. All rights reserved
Kurumsal Bakım Çalışanlarının Gözünden Bakım Emeği ve Pandemi Sonrası Uzun Dönemli Yaşlı Bakımı: Niteliksel Bir Araştırma
No full textCOVID-19 salgınının ortaya çıkışı ile dünya gündemine oturan uzun dönemli bakım politikası tartışmaları bakım emeğinin ve evrensel bakım hizmeti sunumunun toplumsal refah açısından önemini ortaya çıkardı. Bu makale, Türkiye’de uzun dönemli bakım hizmetleri bağlamında bakım emeğinin, bakım emeği çalışanlarının perspektifinden bir değerlendirmesini sunmakta ve evrensel sosyal bakım hizmetinin önemini bakım emeği çerçevesinde tartışmaktadır. Araştırmanın verisi kamu ve belediyeye ait ve özel uzun dönemli bakım kurumlarında çalışmakta olan 11 bakım çalışanı ile gerçekleştirilen yarı yapılandırılmış derinlemesine görüşmelerin niteliksel çözümlemesine dayanmaktadır. Bu bağlamda sosyal bakım çalışanlarının bakıma atfettikleri anlamlar, bakım emeğinin sınırlarına ilişkin algıları ve emek piyasasındaki durumları tartışılmaktadır. Araştırmanın sonucu, pandemi sonrası evrensel sosyal hizmetlerin ve bakım çalışanlarının çalışma koşullarının iyileştirilmesinin öneminin altını çizerken, toplumsal refah için temel iş olan ücretli bakım emeğinin değerli kılınarak sosyal bakım hizmetlerinin evrensel olarak sunulmasının önemini de vurgulamaktadır
The use of mentalization-based techniques in online psychodynamic child psychotherapy
No full textObjective: Psychodynamic child psychotherapy is an evidence-based approach for a range of child mental health difficulties and needs to constantly adapt to meet the needs of children. This study is the first to investigate whether the use of mentalization-based interventions (i.e., a focus on promoting attention control, emotion regulation, and explicit mentalization) predicted a good therapeutic outcome in online psychodynamic child therapy sessions conducted during the COVID-19 pandemic. Methods: The sample included 51 Turkish children (M-age = 7.43, 49% girls) with mixed emotional and behavioral problems. Independent raters coded 203 sessions from different phases in each child's treatment using the Mentalization-Based Treatment for Children Adherence Scale (MBT-CAS). Results: Multilevel modeling analyses showed children with higher emotional lability benefited more from attention control interventions compared to those with lower emotional lability. Discussion: Interventions that focus on developing the basic building blocks of mentalizing may be effective components of therapeutic action for online delivery of psychodynamic child psychotherapy, especially for children with greater emotional lability
Experiences of Children During the Pandemic: Scrutinizing Increased Vulnerabilities in Education in the Case of Turkey
Get PDFThe lengthy time of school closure was one defining factor in understanding child well-being during the pandemic in a context where school as a relational space holds great importance for children, particularly those from a low socioeconomic background. Considering this significant aspect of lengthy school closure during the pandemic in Turkey, this article explores children’s experiences concerning their day-to-day access to education, digital inequalities, housing conditions, and changing context of relations with peers and teachers. The article also explores the meaning that children attribute to school as a relational space where they shape their intergenerational and generational relations. The absence of the school in children’s lives for almost 2 years has been a major source of longing for such significant childhood space. Following our earlier work on the children’s negotiation of well-being within the boundaries of the relational spaces of home and school, this article looks into how children negotiate their well-being in a pandemic environment where school as a relational space has changed its meaning and where children’s caretakers’ (teachers, parents, and other) vulnerabilities have also increased. The analysis draws on the qualitative fieldwork carried out with 50 children during the summer of 2020 in Turkey. We aim to reflect on the experiences from children’s perspectives within the boundaries of the constraints that the pandemic has generated. This article also discusses how COVID-19 has widened the gap and increased vulnerabilities among the already disadvantaged groups and gender in terms of available resources and their allocation as it is reflected in time use that portrays the meaning that children attribute to their own experience during the pandemic. © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG
Comparison of nutritional behaviors of with autism spectrum disorder and typically developing children and examination of their families' nutritional knowledge levels
Get PDFÖZET: Bu çalışmada, otizm spektrum bozukluğu olan ve tipik gelişen çocukların beslenme davranışlarını karşılaştırılması ve ebeveynlerinin beslenme bilgi düzeylerinin incelenmesi amaçlanmıştır. Araştırma Balıkesir ilinde yaşayan 3-6 yaş arasında 69 (33 otizm tanısı almış, 36 tipik gelişim gösteren) katılımcı ve bu çocukların ebeveynleri ile yürütülmüştür. Araştırmada kullanılan anket formunda çocuklara ve ebeveynlerine ait demografik bilgiler, çocukların beslenme davranışlarını saptamak amacıyla ‘Çocuklarda Yeme Davranışı Anketi’ (ÇYDA) ölçeği, besin tüketim sıklığı formu ve ebeveynlerinin beslenme bilgi düzeylerini belirlemek amacıyla ‘Yetişkinler İçin Beslenme Bilgi Düzeyi’ (YETBİD) ölçeği kullanılmıştır. Otizm tanısı almış 33 çocuğun %21.2’si kız, %78.8’i erkektir (p<0.05). Otizmli çocukların ara öğün tüketiminin tipik gelişen çocuklara kıyasla daha az olduğu saptanmış ve fark önemli bulunmuştur (p<0.05). Otizm spektrum bozukluğu olan çocuklarda %69.7 oranında sevdiği besini tüketemeyince sinir atağı yaşama durumu gözlenerek tipik gelişen çocuklardan daha yüksek orana sahip oldukları saptanmıştır (p<0.05). Otizmli çocukların %81.8’inin yemek seçtiği saptanmıştır (p<0.05). Tipik gelişen çocukların %2.8’i bağırsak problemi yaşarken otizmli çocukların %45.5’i bağırsak problemi yaşamaktadır (p<0.05). Çocuklarda Yeme Davranışı Anketi ölçeği sonucunda otizmli çocukların daha fazla duygusal aşırı yeme davranışı sergilediği saptanmıştır (p<0.05). Tipik gelişen çocukların ebeveynlerinin eğitim düzeyi otizmli çocukların ebeveynlerine kıyasla daha yüksektir (p<0.05). Beslenme ve sağlık arasındaki ilişki sorgulandığında tipik gelişim gösteren çocukların ebeveynleri daha yüksek puan aldığı gözlenmiştir (p<0.05). Çalışma sonucunda otizmli çocukların tipik gelişim gösteren akranlarına kıyasla beslenme konusunda daha çok problem yaşadıkları ve ailelerinin beslenme konusundaki bilgilerinin daha az olduğu saptansa da bu konuda daha büyük kapsamlı yapılacak destekleyici çalışmalara ihtiyaç vardır.ABSTRACT: This study aimed to compare the nutritional behaviors of children with autism spectrum disorder and children with typical development, and to examine the nutritional knowledge levels of their parents. The study was conducted with 69 (33 diagnosed with autism, 36 typical development) participants aged 3-6 years living in Balıkesir and their parents. In the questionnaire used in the study, demographic information of children and their parents, 'Eating Behavior Questionnaire for Children' scale to determine the nutritional behaviors of children, food consumption frequency form and the 'Nutrition Knowledge Level for Adults' scale to determine the nutritional knowledge level of their parents were used. Among 33 children diagnosed with autism, %21.2 were girls and %78.8 were boys (p<0.05). It was determined that the consumption of snacks in children with autism was less than those of children with typical development, and the difference found to be statistically significant (p<0.05). Children with autism spectrum disorder found to have a higher rate of nervous attack when they could not consume their favorite food at a rate of %69.7 (p<0.05). It determined that %81.8 of children with autism choose food (p<0.05). While %2.8 of children with typical developement had intestinal problems, %45.5 of children with autism had intestinal problems (p<0.05). As a result of the Child Eating Behavior Questionnaire scale, it determined that the autistic group exhibited more emotional overeating behavior (p<0.05). The education level of parents of children with typical developement was higher than parents of children with autism (p<0.05). When the relationship between nutrition and health was questioned, it was observed that the parents of children with typical development scored higher (p<0.05). As a result of the study, it has been determined that children with autism have more problems with nutrition compared to their children with typical developement peers and their families have less knowledge about nutrition, but there is a need for more comprehensive supportive studies on this subject
Measurement of the inclusive t(t)over-bar production cross section in the lepton plus jets channel in pp collisions at ?s=7 TeV with the ATLAS detector using support vector machines
Get PDFA measurement of the top quark pair-production cross section in the lepton + jets decay channel is presented. It is based on 4.6 fb(-1) of root s = 7 TeV pp collision data collected during 2011 by the ATLAS experiment at the CERN Large Hadron Collider. A three-class, multidimensional event classifier based on support vector machines is used to differentiate t (T) over bar events from backgrounds. The tt production cross section is found to be sigma(t (t) over bar) = 168.5 +/- 0.7(stat)(-5.9)(+6.2) (syst)(-3.2)(+3.4) (lumi) pb. The result is consistent with the Standard Model prediction based on QCD calculations at next-to-next-to-leading order
Akıllı şehir etiği: Pakistan’daki teknik paydaşların anlayışları
Get PDFABSTRACT: As the world has raced ahead and developed into a collection of wired cities and connected on the grid communities, we have also become effaced with challenges of urban sprawl, gentrification, pollution and climate change (Halegoua, 2020). Big tech companies as well as multiple governments around the globe are putting forth smart city technologies as a possible solution to our emerging problems, citing the power of modern technologies when data-driven systems as a solution to complex urban issues (Cocchia, 2014). At the same time science and technology research is destabilizing the assumption that technology is value neutral instead scholars posit the technological artifacts are imbued with consequences norms as well as values which can encourage certain behaviors while discouraging others (Costanza-Chock, 2020; Winner, 1980). Furthermore, the black box nature of AI systems further motivates the need to study the “less-tangible” aspects of algorithms and algorithmic thinking (Young & Kitchin, 2020, p. 3). This research undertakes the study of these ‘less-tangible’ aspects of technological artifacts and their creation and investigates how they manifest in the context of Smart City projects in Pakistan. In order to achieve this goal this research focuses on technical stakeholders which may be critically positioned to shed light upon what ethical considerations, deliberations, and concerns surface in the act of technological creation in the country. In so doing this research hopes to add to a conversation that has so far been restricted to western economies and allow the deconstruction of how data harms manifest and low-to-middle income countries. By conducting 12 semi structured participant interviews this research was able to show that while technical stakeholders are unsure of the local implementations of smart city projects the same cannot be said for datafication processes, perceptions of which, were largely positive. It also shows that trust in government-led initiatives is low in comparison to corporate initiatives, due to historical political instabilities. Although participants displayed some understanding of common ethical concerns their knowledge of how these issues can affect local communities was sparse at best, and inclination towards security at the cost of privacy also reared its head in the data. These insights show that local contexts severely impact how ethical choices are made and highlight the importance of including local stakeholders in applications of smart technology. In conclusion this research underscores the importance of mapping data ethics in previously understudied parts of the world so that a fuller picture of what ethics of smart cities means on a global scale can be constructed.ÖZET: Dünya hızla ilerleyip kablolu şehirlerden ve şebekeye bağlı topluluklardan oluşan bir koleksiyona dönüşürken, kentsel yayılma, soylulaştırma, kirlilik ve iklim değişikliği gibi sorunlarla da boğuşur hale gelindi (Halegoua, 2020). Büyük teknoloji şirketleri ve dünyanın dört bir yanındaki çok sayıda hükümet, karmaşık kentsel sorunlara çözüm olarak veriye dayalı sistemleri devre sokarken, modern teknolojilerin gücüne atıfta bulunarak, ortaya çıkan sorunlarımıza olası bir çözüm olarak akıllı şehir teknolojilerini öne sürüyor (Cocchia, 2014). Aynı zamanda bilim ve teknoloji araştırmaları, teknolojinin değer açısından tarafsız olduğu varsayımını sorgularken, birçok araştırmacı, teknolojik eserlerin bazı normların yanı sıra belirli davranışları teşvik ederken diğerlerini de caydırabilecek değerlerle dolu olduğunu öne sürmektedir (Costanza-Chock, 2020; Winner, 1980). Ayrıca, yapay zeka sistemlerinin kara kutu niteliği, algoritmaların ve algoritmik düşüncenin "daha az somut" yönlerini inceleme ihtiyacını daha da motive etmektedir (Young & Kitchin, 2020, s. 3). Bu araştırma, teknolojik eserlerin ve bunların yaratımının bu 'daha az somut' yönlerini incelemeyi üstlenmekte ve Pakistan'daki Akıllı Şehir projeleri bağlamında bunların nasıl ortaya çıktığını araştırmaktadır. Bu amaca ulaşmak için bu araştırma, ülkedeki teknolojik yaratım eyleminde hangi etik düşüncelerin, müzakerelerin ve kaygıların ortaya çıktığına ışık tutacak şekilde eleştirel bir konuma sahip olabilecek teknik paydaşlara odaklanmaktadır. Böylece bu araştırma, şimdiye kadar Batı ekonomileriyle sınırlı kalan bir tartışmaya katkıda bulunmayı ve verilerin açık ve düşük-orta gelirli ülkelere nasıl zarar verebileceğinin yapısökümüne öncü olmayı ummaktadır. Bu araştırma bağlamında, 12 yarı yapılandırılmış katılımcı görüşmesi gerçekleştirilmiştir. Teknik paydaşların, akıllı şehir projelerinin yerel uygulamalarına şüpheyle baktıkları, ancak aynı şeyin, paydaşlar tarafından genel olarak olumlanan verileştirme süreçleri için söylenemeyeceği gösterilmiştir. Ayrıca, tarihsel siyasi istikrarsızlıklar nedeniyle hükümet öncülüğündeki girişimlere duyulan güvenin kurumsal girişimlere kıyasla düşük olduğu da ortaya konmuştur. Katılımcılar yaygın etik kaygılar konusunda bir miktar anlayış sergilemiş olsalar da, bu konuların yerel toplulukları nasıl etkileyebileceği konusundaki bilgileri en iyi ihtimalle seyrek olarak ifade edilebilirken, mahremiyet pahasına güvenlik değerinin öncelenmesi de verilerde kendini göstermektedir. Bu içgörüler, yerel bağlamların, etik seçimlerin nasıl yapıldığını ciddi şekilde etkilediğini göstermekte ve akıllı teknoloji uygulamalarına yerel paydaşların dahil edilmesinin önemini vurgulamaktadır. Sonuç olarak bu araştırma, akıllı şehir etiğinin küresel ölçekte ne anlama geldiğine dair daha kapsamlı bir resmin oluşturulabilmesi için dünyanın daha önce yeterince görece çalışılmamış bölgelerinde veri etiğinin haritalandırılmasının önemini vurgulamaktadır