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Diffuse Pulmonary Lesions Due to Invasive Fungal Infection in an Immune-capable Male: A Case Report
No full textIntroduction: Invasive fungal pulmonary infection is a fungal illness caused by many species of fungi, including Aspergillus, generally presenting as life-threatening hazards to people with compromised immune systems. Although instances in immunecompetent individuals are infrequent, a recently published report detailed active lung infection within an immune-competent patient at postmortem. We report a rare instance of invasive fungal infection (IFI) in an immune-capable male, exhibiting diffuse systemic lesions.
Case Report: A 33-year-old male approached our facility, complaining of chest discomfort and dyspnea lasting for 3 months. Upon clinical examination, he looked emaciated and presented with sinus symptoms. A radiographic examination showed indistinct lesions in the lower left lobe of the lung. Bronchoscopy as well as bronchoalveolar lavage (BAL) were conducted, before the commencement of oral antibiotic treatment. The lavage findings were negative for staining techniques (e.g., acid-fast bacilli (AFB)), and culture demonstrated many septate hyphae on the fungal screen. Histopathological analysis of lung tissue (via bronchoscopy) revealed persistent granulomatous inflammation with apical fungal hyphae, diagnostic of aspergillosis. Further cultures confirmed the presence of Aspergillus fumigatus, leading us to commence voriconazole treatment. The patient had a notable recovery, evidenced by gaining weight and a recovered appetite within a brief timeframe. His symptoms improved within three months of medication, allowing him to return to almost normal life.
Conclusion: This case underscores the identification of IFI in an immune-capable patient exhibiting extensive nodular lesions throughout the respiratory tract, mediastinum, and belly. Clinicians must uphold a heightened concern for aspergillosis in persistent pneumonia and diffuse nodular lesions, despite patients having no conventional risk factors
CT 3D Reconstruction Technology and AI Recognition Technology in the Application of Rib Fibrous Dysplasia: A Case Report
No full textBackground: Primary rib tumors are relatively rare and more difficult to diagnose compared to other tumors, leading to a higher risk of misdiagnosis.
Case: The patient was a 23-year-old male who presented with intermittent right-sided chest pain for six months. Six months prior, he developed right chest wall pain without an obvious cause, characterized by dull pain and occasional stabbing sensations, often accompanied by coughing and white mucus production, but no fever, night sweats, nausea, or vomiting. Symptoms would resolve on their own after about a week. CT 3D reconstruction technology and AI recognition suggested a rib tumor, requiring surgical removal. The surgery was successful, and the patient recovered well with no recurrence.
Conclusion: Primary rib tumors are rare. Using CT 3D reconstruction and AI recognition technology can improve preoperative diagnosis and assist in surgical planning
Polycystic Ovary Syndrome Herbal Treatments and Medicinal Plants: A Comprehensive Review
No full textPolycystic ovary syndrome (PCOS) represents one of the most common endocrine disorders affecting women of reproductive age, serving as a major contributor to infertility on a global scale, with an estimated prevalence varying from 6 to 20% worldwide. PCOS is a complex syndrome defined by hyperandrogenism, irregular ovulation, and the presence of polycystic ovarian morphology. This syndrome is often associated with metabolic complications, including obesity, dyslipidemia, and an elevated risk of insulin resistance and developing type 2 diabetes. Symptoms include menstrual irregularities, weight gain, hirsutism, acne, and infertility. The presently available conventional treatment options for PCOS include hormonal contraceptives, insulin sensitizers, anti-androgens, and ovulation-inducing agents. While these treatments may offer symptomatic relief, they often entail potential side effects and do not adequately address the underlying cause of this syndrome. Herbal remedies have been used for centuries across cultures to manage various disorders due to their cost efficiency, availability, and safe nature. Several studies have demonstrated the efficiency of herbal remedies in the treatment of female reproductive disorders, including PCOS. This review comprises an extensive survey of the latest animal and clinical studies concerning plants and phytochemicals that have demonstrated effectiveness in alleviating symptoms associated with PCOS, as well as treating the underlying mechanisms involved in their efficac
Child-free in the Perspective of Positive Law in Indonesia
No full textThe decline in birth rates in Indonesia, reflected in the decreasing Total Fertility Rate and the increasing percentage of women choosing to be child-free, raises concerns about the country’s demographic structure. The child-free phenomenon is influenced by external factors such as economic and social conditions, as well as internal factors like decision-making maturity and family experiences, significantly impacting Indonesia’s population dynamics. From an Islamic legal perspective, the decision not to have children or to be child-free is recognized and permitted, considering the underlying motives. According to Imam Al-Ghazali, the act of rejecting the existence of children, if done before the sperm enters the woman’s womb, is legitimate and permissible. Good motives, such as financial or health reasons, are acceptable, while incorrect motives render the child-free decision impermissible. Legally, the choice to be child-free is protected by the Indonesian constitution and laws that guarantee human rights, personal freedom, and gender equality. Health policies and family planning also support the right of individuals or couples to decide on the number of children or to choose not to have children. Although there are no regulations prohibiting being child-free, the state still views the purpose of marriage as having good and healthy offspring, while respecting individual rights and freedoms. The state is expected to create policies that support individual choices while maintaining population balance to prevent potential sex recession and ensure the continuity of future generations
Resolution Of Shariah Economic Bankruptcy Disputes Through a Non-Litigation Approach: Analysis Based On Wahbah Az-Zuhaili's Legal Theory
No full textThis paper aims to understand to resolution of bankruptcy disputes according to Wahbah Az-Zuhaili in Al-Fiqh Al-Islam Wa Adilatuhu. This issue is especially topical given the number of companies that have gone bankrupt due to the pandemic. In this paper, the authors use descriptive qualitative methods and collect data using a documentation technique. In the research that will be carried out by this author, it is descriptive which aims to describe data related to the subject matter that has been formulated. The results show that Wahbah az-Zuhaili, as a contemporary ulama, he describes dispute resolution through ash-Sulh as a form of lenient attitude to obtain some of the existing rights. As a result, even if not in full, the plaintiff can obtain some of his rights
Government Expenditures Have Implications for Economic Growth and Poverty Levels in Papua
No full textThis study examines the impact of government spending on poverty, with economic growth acting as a mediating variable in Papua. The data used in this research is secondary, focusing on the socio-economic conditions of 29 districts/cities in Papua Province. This study employs quantitative analysis to assess the effects of government spending on education and health on both economic growth and poverty levels in Papua Province during the 2017-2021 period. The findings indicate that government spending significantly affects poverty levels in Papua Province, with economic growth serving as a mediator
Does the PJBL Learning Model Based on Mobile Apps and Motivational Effects on Students' Critical Thinking Skills in Entrepreneurship Courses?
No full textEntrepreneurship learning is carried out gradually and continuously in colleges and universities. The problem is the large number of unemployed. It is suspected that there are influencing factors, namely: the skill competencies of college graduates do not match the needs of market demand. The Entrepreneurship Lecture was held to introduce the world of entrepreneurship and equip students to develop an entrepreneurial spirit. This study aims to determine the effect of project-based learning (PjBL) based on mobile apps and learning motivation on students’ critical thinking skills in entrepreneurial courses. This study has a quantitative design. The study population comprised 116 students from the Economics Education Department of PGRI Jombang University. The selected sample included 54 students through the survey. Data analysis was performed using multiple linear regression. The results of the study indicate that: 1) There is an effect of the PjBL model based on mobile apps on critical thinking skills. 2) There is an effect of learning motivation on critical thinking skills. This study provides practical implications where mobile app-based PjBL provides convenience in managing information related to learning activities in entrepreneurship courses
Leveraging Diagnostic Assessment Aligned to Differentiated Learning: Voices of English Language Teachers
No full textThe Merdeka Belajar curriculum emphasizes flexibility and student-centered learning, making diagnostic assessment crucial for teach English effectively. By identifying each student’s language proficiency and learning needs early on, teachers can tailor instruction to meet diverse abilities within the classroom. This aligns with the curriculum’s goal of fostering independent and meaningful learning experiences. Diagnostic assessment also supports differentiated instruction, ensuring that students receive targeted support and challenges based on their individual progress. As a result, it enhances both student engagement and mastery in English, making it an essential tool for teachers implementing Merdeka Belajar curriculum. Despite the curriculum’s clear benefits, there is a pressing need for a study investigating how teachers utilize diagnostic assessments to identify students’ learning profiles, interests, and readiness. Therefore, this study intends to capture the utilization of diagnostic assessment to promote the differentiated learning, especially in junior high school. By employing qualitative research design, this study involved 19 English teachers in state and private junior high schools in Semarang, Central Java, Indonesia. Participatory observation and semi-structured interviews were used as the instrument to collect data. Through the qualitative analysis, this study revealed that English teachers utilized some tools such Kahoot!, quizzes, Google Form, and questionnaires to implement diagnostic assessments. This study also delineated seven crucial procedures that English teachers conducted to successfully execute differentiated learning. These measures encompass structuring classroom arrangements, employing varied educational resources, implementing adaptable instructional strategies, and performing consistent assessment alongside prompt feedback. The incorporation of diagnostic assessment in the Merdeka Belajar curriculum is essential for developing effective differentiated learning modules. This method allows teachers to cater to the distinct needs of each student, hence improving their learning experiences and academic results
From Tuberose to Tourism by Leveraging Renewable Energy and Technology for Sustainable Development in Doplang Village
No full textThis study investigates the integration of solar energy systems in the village of Doplang, Indonesia, to promote sustainable rural tourism centered around its cultural asset–the tuberose (bunga sedap malam). A mixed-method approach evaluates the impact of renewable energy technologies on the community’s readiness for eco-tourism development. Data collection includes semi-structured interviews, field observations, quantitative surveys, gathering insights on community perceptions, energy usage, and cost savings associated with solar battery systems. Interviews with local villagers, business owners, and government representatives provide qualitative insights into attitudes toward solar energy adoption and its implications for tourism practices. Field observations document the current energy infrastructure, while quantitative surveys assess energy needs, post-installation savings, and readiness to adopt solar-powered infrastructure. Preliminary findings indicate that the solar battery system generates 4.8 kWh of energy daily, leading to a 30% reduction in energy consumption and monthly electricity cost savings of IDR 675,000, contributing to an annual reduction of 1.56 tons of carbon emissions. By powering essential infrastructure, such as the village hall and local businesses, the solar system supports the burgeoning eco-tourism sector. The expected return on investment (ROI) within four to five years enhances the village’s economic state. This study highlights the need for policy support, including subsidies and training programs, to facilitate solar energy adoption, offering a scalable model for rural villages in Indonesia
The Role of Organizational Culture in Enhancing Lecturer Performance: Mediating Effects of Work-Life Balance in LLDIKTI Region 2
No full textThis study explores the relationship between work-life balance (WLB), organizational culture (OC), and lecturer performance (LP) in higher education institutions under LLDIKTI Region 2. The research specifically investigates how organizational culture mediates the impact of work-life balance on lecturer performance. Using a sample of 220 lecturers, the data were analyzed via path analysis to assess both direct and indirect effects. The results show that work-life balance positively influences organizational culture, which in turn enhances lecturer performance. However, the direct effect of work-life balance on performance was found to be non-significant, suggesting that organizational culture plays a crucial mediating role. This research provides novel insight into how institutional culture mediates the effects of personal well-being on professional outcomes, offering significant implications for policy development in higher education. A strong focus on organizational culture can maximize the benefits of work-life balance initiatives to boost lecturer performance in Indonesian higher education institutions