AIJR Preprints
Not a member yet
188 research outputs found
Sort by
COVID-19: Impact on the Financial Services Sector Index
Get PDFThe COVID-19 has impacted the social as well as professional lives of people. This pandemic could be one of the most significant challenges faced by the financial services industry. Financial institutions around the world are closely monitoring and facing with the challenges of COVID-19 pandemic. Institutions are coming up with more expertise team to understand the immediate effect of this pandemic to business economies, society and other stakeholders to provide better services to the customers in this highly volatile business environment. Service sectors, including aviation, travel, and tourism, are likely to be hit the hardest. All eyes tuned to the financial services industry to see if they can respond in a manner that reduces the global economic impact of COVID-19. This pandemic has already had a serious impact on the global financial markets, including India, and it may have accounting and reporting implications for many entities. As Corona virus started to spread all over, and more information comes to light, the after effects are more severe than expected by the experts. This paper made an attempt to study the impact of covid-19 on the financial services sector index before and after Covid-19 pandemic
Violacein, A Microbial Antiviral Product: Does Play Key Role as Active Agent Against SARS-CoV-2?
Get PDFViolacein, a microbial product was characterized after continuous attempts to feature it, based on degradation and synthesis procedures, at the University of Liverpool (England), from 1958 to 1960 and only at 2001 was chemically synthesized. It is a quite known antimicrobial and antiviral natural product. New attempts to solve the infection caused by, or find the proper therapy for, COVID19, must adopt multidisciplinary approach. The aim of the current study is to address the targets, possible strategies and perspectives of new technologies and therapies on COVID19. It also hypothesizes the potential of using the therapeutic drug called violacein as multifunctional agent to treat patients at different COVID19 contamination stages. Our experience and knowledge about violacein has led us to extrapolate the potential use of this pigment. Violacein multiple biological activities as also knowledge on its toxicity and antiviral activity enabled suggesting that it could be the new important agent used to treat COVID19. Violacein is highly likely to act as protease inhibitor, at ACE2 receptor level and as immunotherapeutic drug against Covid19. In term of chemotherapy, it will be discussed the actual antiviral used against COVID19, such as, thalidomide, ivermectin and melatonin, among others
Universal Maternal Rights: A Matter of Life and Death
Get PDFChildbirth has been a part of our lives since the beginning of time. Without the process none of us would be alive today. So why is it that maternal mortality remains one of the greatest inequities in the world? To date, approximately 500, 000 women die annually due to the lack of appropriate prenatal and obstetric care. Difficulties arising with childbirth cannot be predicted. However, the way in which we react to a situation can have a lasting, positive effect on the countries and the women who are at risk. The ways in which to help reduce the large number of maternal deaths in developing countries is not complicated and can be achieved if it is made a priority. In conclusion, there are multiple obstacles in regard to succeeding the highest achievable standard of health globally. With the education of evolving scientific methods, and the collaboration of humanitarian views, the welfare and health of women and their children, can be internationally restored. With the education of evolving scientific methods, and the collaboration of humanitarian views, the welfare and health of women and their children, can be internationally restored
Value of Newborn Screening Programs for Severe Combined Immunodeficiency
Get PDFSevere Combined Immunodeficiency Disease (SCID) is life-threatening disease of infancy and childhood characterized by recurrent infections and failure to thrive. Given the modern medical progress made available for treating SCID, early identification of these children is paramount to their wellbeing and overall survival into adulthood. Newborn screening (NBS) programs provide the opportunity to identify SCID patients before life-threatening infections can manifest. The T-cell receptor excision circles (TRECs) assay currently used for SCID screening has been shown to satisfy all parameters of an effective screening test. Its widespread use is indicated by the time-sensitive nature of the disease, its efficacy in reducing morbidity and mortality in these patients, and the cost-effectiveness of prompt recognition versus long-term management. While immensely beneficial, screening tests still hold limitations that require analyzing. Follow-up measures for SCID identification programs have identified ambiguity and inconsistency among testing algorithms across facilities and technical errors that have causes inaccurate results. Considering fewer than 20% of SCID patients report a positive family history and the lethal consequences of disease if left untreated, a screening program is a highly valuable tool for early diagnosis and prompt intervention
Global Governance and the WHO’s Mandate Post-COVID-19 Crisis
Get PDFThe COVID-19 has renovated the debate about global health governance. A number of scholars have proposed that the World Health Organization should assume the position of a central coordinator with hierarchical powers, demanding nation-states to “share their sovereignty”. This article presents four main objections to this project. First, when international institutions receive leverage, they use to impose “one-size-fits-all” policies, which conflicts with the characteristic heterogeny across countries. Second, geopolitical questions and the distribution of power in multilateral institutions put developing countries in a position of vulnerability within a hierarchical order. Third, the risk of crowding out parallel initiatives, especially from non-state actors. Fourth, decisions about health can have a major impact on countries, which may thwart the internal democratic principle. A Pareto improvement would be possible by strengthening the WHO’s operational capacity and its ability to issue technical guidance and coordinate with countries. To test this hypothesis, this study analyses the possible influence of the WHO’s guidance in the first year of the coronavirus health crisis, from January 2020 to January 2021, in 37 countries reported in the World Values Survey Wave 7 (2017-2020). The OLS regression performed shows a statistically significant negative relationship between the trust in the WHO, assumed as a proxy for the level of the organization's penetration, and the number of cases of COVID-19 (per million people) in the countries of the sample. These findings reinforce the hypothesis that there is a valid case for the countries to strengthen the WHO’s mandate post-COVID-19, but they should enhance the operations of provision of reliable information and support. Nation-states, in particular the developing ones, should eschew the temptation to create a hierarchical global health structure, which may not only fail due to countries’ asymmetries but is likely to create losers in the process
Effects of COVID-19 on Global Healthcare Research and Management
Get PDFThe Coronavirus Infectious Disease 2019 (COVID-19) pandemic has affected most nations at all levels of functioning, individual to governmental. Therefore, it is imperative to evaluate the effects the virus has had on one of the most important socioeconomic global sectors – healthcare. This comprehensive literature review explores key, recent research and management strategies that have been undertaken in healthcare systems around the world in order to make meaningful attempts at identifying the etiology, diagnosis, and treatment the disease, and combating the spread of this deadly virus. Healthcare facilities have implemented a variety of changes, all geared towards reducing non-emergency patient visits and preventing transmission of the infection; this includes shifting appointments to online modality via telecommunication use, altering remedial options and procedures, and developing more effective personal protective equipment (PPE). Efforts have also been made to define appropriate treatment methods as well as a potential cure for COVID-19; many vaccines and antiviral drugs are being designed or undergoing clinical testing, and symptom management approaches are being employed along with careful evaluation or recommendation of already available medications to counter the disease
Psychological Impact of COVID-19 on Dental Interns; A Reality Check
Get PDFBackground: The COVID-19 pandemic and the associated lockdown had universities to limit operation and restrict contact through recommended social distancing. it had an enormous impact at both societal and educational level. This study focuses on the psychological impact of the pandemic on dental interns
Methods: An online structured anonymous survey composed of 20 questions was sent to interns of various dental colleges in India. The questionnaire consisted of questions pertaining to demographic data, questions assessing the perceived impact of COVID?19 outbreak questions regarding their stress levels, fears and questions for assessing the psychological reactions, feelings and emotions experienced by students whilst thinking at COVID?19 outbreak were measured by the Generalized Anxiety Disorder 7-Item Scale
Results: The perceived fears like Uncertainity about the future is seen among 60% of the participants followed by fear of contacting virus in 26% of the participants. S also shows most of the interns have fear, anxiety and sadness while thinking about covid. GAD scale 7 assessment showed mild to moderate depression in interns during the covid lockdown.
Conclusion: The study shows that interns were psychologically affected by covid 19 lockdown. which were significantly associated with fear and anxiety. it is imperative that adequate support is needed for dental interns in the midst of this pandemic and beyond
Face Mask Detection and Alert System
Get PDFIn today’s era, as we all know how the year 2020 has brought an alarming pandemic with it and day by day, we are reaching a new peak of COVID cases. And due to which a main contribution asked from all the citizens is to follow all the safety norms to soothe the condition. One of the norms states to wear facemask all the time immediately after stepping out of their home. This paper proposes one of the methods to ensure that at least all people coming under any Closed-Circuit Television (CCTV) surveillance wears masks and that too properly. In this system we are using locally linear embedding (LLE) algorithm for face detection and convolutional neural network (CNNs) to reconfigure the image to fit into the network. And the neural network is trained with the help of image dataset. The method attains training accuracy and validation accuracy up to 99.87% and 93.41% respectively on two different datasets. If the system found out a person with no mask or not wearing it properly an alarm buzz outs to alter
Critical COVID-19 Pneumonia with Acute Respiratory Failure in a Healthy 12-year-old Girl
Get PDFWe present an otherwise healthy, fully immunized 12-year-old girl who was transferred intubated and ventilated to our Paediatric Intensive Care Unit with fever, cough, and acute respiratory failure. The epidemiologic history was positive for COVID-19, and, furthermore, she tested PCR positive resulting from a nasopharyngeal swab. CT of the thorax revealed bilateral consolidation with the tree-in-bud signs. Her condition required artificial ventilation support for 13 days. Remdesivir, pronation, high dose Ascorbic acid with Thiamine, and combined antimicrobial therapy were successfully used. Our patient made a full clinical recovery. The case demonstrates that even though critical course of COVID-19 infection in children is scarce, it might occur. We hereby would like to share our experience with the medical community
What Do We Know About and What Could Be the Strategy Adopted to Treat Mucormycosis on Post-COVID-19 Cases? Is It an Adjuvant Nanomaterial?
Get PDFUnfortunately, Coronavirus disease 2019 (COVID-19) remains a significant public health issue worldwide, mainly in the USA, India and Brazil. The 2nd wave of COVID-19 has reached India first. The country has been making great effort to stabilize its current condition but, unfortunately, mucormycosis infection (or black fungus) associated with COVID-19 has emerged as another threat to the country and, most likely, to Brazil. It may have happened due to excessive glucocorticoid using, since the widespread administration of this drug can lead to secondary fungal infections. Mucormycosis is generated by a group of molds called mucormycetes; it is a rare, although likely fatal, contamination when patients are not properly treated. The concerning factor lies on the fact that the high COVID-19 incidence recorded in the first wave of it has increased even faster in its second wave in India; there have been some concerning cases in Brazil, as well. The current overview addresses the current therapies used to treat mucormycosis worldwide, as well as potential and new drugs for such a specific treatment. Anti-mucormycosis adjuvants and nanomaterials are the most interesting alternatives to treat patients with post-COVID-19 mucormycosis