Manisa Celal Bayar Üniversitesi Akademik Arşiv Sistemi
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Evidence for the decay Bc+ → J/ψ 3π+2π-
No full textEvidence is presented for the decay B-c(+) -> J/psi 3 pi(+)2 pi(-) using proton-proton collision data, corresponding to an integrated luminosity of 3 fb(-1), collected with the LHCb detector. A signal yield of 32 +/- 8 decays is found with a significance of 4.5 standard deviations. The ratio of the branching fraction of the B-c(+) -> J/psi 3 pi(+)2 pi(-) decay to that of the B-c(+) -> J/psi pi(+) decay is measured to be B(B-c(+) -> J/psi 3 pi(+)2 pi(-))/B(B-c(+) -> J/psi pi(+)) = 1.74 +/- 0.44 +/- 0.24, where the first uncertainty is statistical and the second is systematic
Do Walking Programs Affect C-Reactive Protein, Osteoprotegerin and Soluble Receptor Activator of Nuclear Factor-Kappaβ Ligand?
No full textAim: To examine the effects of 10-week walking programs on maximal oxygen consumption, body composition, serum lipids, highly-sensitive C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappa beta ligand. Method: Twenty-seven middle-aged men (40-60years) walked for ten weeks, five days per week, 40-52min per day at either moderate or high intensity (similar to 5.95 +/- 0.26km/h and similar to 7.64 +/- 0.36km/h; 50-55% and 70-75% maximum heart rate reserve, respectively). Non-walking, sedentary men served as controls (n=13). Estimated maximal oxygen consumption, body composition, lipid profile, highly-sensitive C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappa beta ligand were determined before and after the study. Results: After 10 weeks, estimated maximal oxygen consumption improved in both exercise groups (p<.05), favoring high-intensity group (p<.05). Body weight, percent body fat, and body mass index reduced significantly in both exercise groups (p<.05). Walking programs did not cause any significant changes in blood lipids, highly-sensitive C-reactive protein, and osteoprotegerin levels; however, soluble receptor activator of nuclear factor-kappa beta ligand levels were found to decrease in high-intensity group (p<.05) and the change observed in both exercise groups was different from the change in control group (p<.05). Conclusion: For protective effects against cardiac risk factors and arterial calcification, high-intensity walking programs are advisable due to the greater improvements in soluble receptor activator of nuclear factor-kappa beta ligand and estimated maximal oxygen consumption
Synthesis, characterization, and antibacterial properties of novel N-heterocyclic carbene (NHC) precursors and their silver complexes
No full textIn this work, a new compound, 1-(3,5-dimethoxybenzyl)-5,6-dimethylbenzimidazole, was prepared by N-alkylation of 5,6-dimethylbenzimidazole with potassium hydroxide and 3,5-dimethoxybenzyl bromide in ethanol. Three 5,6-dimethylbenzimidazolium salts were obtained by quaternisation of 1-(3,5-dimethoxybenzyl)-5,6-dimethylbenzimidazole with 4-cyanobenzyl bromide, 4-tert-butylbenzyl bromide, and bromoethane, respectively. Deprotonation of these with silver oxide afforded NHC silver complexes in good yields. The formation of the compounds was validated by nuclear magnetic resonance, Fourier transform infrared spectroscopy, elemental analysis, and LC–MS/MS (only for the silver complexes) methods. The complexes were found to be stable against air and light by 1H NMR analysis of their solutions after one week. Experimental studies were carried out on the antibacterial properties of both benzimidazolium salts and NHC silver complexes against pathogenic strains of Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Enterobacter cloacae. Inhibition zone and minimum inhibitory concentration values were determined. On the basis of these data, it was concluded that all the compounds studied were antibacterial against all the bacterial chains tested, particularly Gram-positive bacteria. The MIC values indicate that the coordination of the NHC ligands to the Ag(I) ion leads to an increase in their antibacterial activity. Bromo[1-(3,5-dimethoxybenzyl)-3-(4-tert-butylbenzyl)-5,6-dimethylbenzimidazolin-2-ylidene]silver showed better activity against S. aureus than the standard antibiotic gentamicin. © Springer-Verlag GmbH Austria, part of Springer Nature 2025
Early stage diabetes prediction by features selection with metaheuristic methods
No full textDiabetes is a metabolic disease that is common worldwide. The number of people suffering from diabetes is expected to increase every year around the world. This means a negative impact on both the comfort of life of individuals and the health system. In this respect, it is important to diagnose the disease at an early stage. The high dimensionality of the data used for diagnostic purposes has a negative effect on the cost and time of the calculation. To avoid this, it is important to select the most valuable features for diagnosis. In this study, feature selection was made using Salp Swarm Algorithm, Artificial Bee Colony Algorithm, Whale Optimization Algorithm and Ant Colony Algorithm using the samples in the UCI (UCI Machine Learning Repository) data store. In order to evaluate the selected features, accuracy, sensitivity and specificity parameters were calculated using k-Nearest Neighborhood (KNN), Naive Bayes (NB), Support Vector Machine (SVM) and Artificial Neural Networks (ANN) methods. In the calculations for the probability of having diabetes, an accuracy rate of 99.04% was obtained with the k-Nearest Neighborhood method
THE RELATIONSHIP BETWEEN MRI FINDINGS, PAIN AND DISABILITY IN THE PATIENTS WITH CERVICAL OSTEOARTHRITIS
No full textTransverse vibrations of tensioned pipes conveying fluid with time-dependent velocity
No full textIn this study, the transverse vibrations of highly tensioned pipes with vanishing flexural stiffness and conveying fluid with time-dependent velocity are investigated. Two different cases, the pipes with fixed-fixed end and fixed-sliding end conditions are considered. The time-dependent velocity is assumed to be a harmonic function about a mean velocity. These systems experience a Coriolis acceleration component which renders such systems gyroscopic. The equation of motion is derived using Hamilton's principle and solved analytically by direct application of the method of multiple scales (a perturbation technique). The natural frequencies are found. Increasing the ratio of fluid mass to the total mass per unit length increases the natural frequencies. The principal parametric resonance cases are investigated in detail. Stability boundaries are determined analytically. It is found that instabilities occur when the frequency of velocity fluctuations is close to two times the natural frequency of the constant velocity system. When the velocity fluctuation frequency is close to zero, no instabilities are detected up to the first order of perturbation. Numerical results are presented for the first two modes. (C) 2000 Academic Press
Modeling and optimization of MHD mixed convection in a lid-driven trapezoidal cavity filled with alumina-water nanofluid: Effects of electrical conductivity models
No full textIn this study, mixed convection in a lid driven trapezoidal cavity filled with Al2O3 water nanofluid under the effect of an inclined magnetic field was numerically investigated for various electrical conductivity models. The top and bottom wall of the trapezoidal cavity were maintained at constant cold and hot temperatures and the top wall is moving at a constant speed in positive x direction. The governing equations are solved with finite element method. Numerical simulations were performed for different values of Richardson numbers (between 0.01 and 25), strength and orientation of the uniform magnetic field (Hartmann number (between 0 and 40), magnetic inclination angle (between 0 and 90)) and solid volume fraction of the nanofluid (between 0 and 0.03) for different electrical conductivity models. It was observed that as the value of the Richardson number, strength of the magnetic field and solid particle volume fractions enhance, discrepancy between the average Nusselt number increases for systems with different electrical conductivity models. Magnetic inclination angle for which the difference between average heat transfer rate is minimized for different electrical conductivity models depends on the side wall inclination angle of the trapezoidal cavity. After performing an optimization study, it was found that the optimum value of magnetic inclination angle is dependent on the electrical conductivity model. (C) 2017 Elsevier Ltd. All rights reserved
Angiokeratoma circumscriptum of the tongue
No full textAngiokeratoma circumscriptum of the tongue is a rare mucocutaneous vascular disorder. To date, only three cases of angiokeratoma circumscriptum of the tongue have been reported in the English literature. In this article, a case with angiokeratoma circumscriptum of the tongue was presented, and all the aspects of this clinical entity including clinical evaluation, differential diagnosis, histopathological features, and treatment modalities were discussed
Turkish League Against Rheumatism (TLAR) Recommendations for the Pharmacological management of Rheumatoid Arthritis: 2018 Update Under Guidance of Current Recommendations
No full textObjectives: This study aims to report the assessment of the Turkish League Against Rheumatism (TLAR) expert panel on the compliance and adaptation of the European League Against Rheumatism (EULAR) 2016 recommendations for the management of rheumatoid arthritis (RA) in Turkey. Patients and methods: The EULAR 2016 recommendations for the treatment of RA were voted by 27 specialists experienced in this field with regard to participation rate for each recommendation and significance of items. Afterwards, each recommendation was brought forward for discussion and any alteration gaining >= 70% approval was accepted. Also, Turkish version of each item was rearranged. Last version of the recommendations was then revoted to determine the level of agreement. Levels of agreement of the two voting rounds were compared with Wilcoxon signed-rank test. In case of significant difference, the item with higher level of agreement was accepted. In case of no difference, the changed item was selected. Results: Four overarching principles and 12 recommendations were assessed among which three overarching principles and one recommendation were changed. The changed overarching principles emphasized the importance of physical medicine and rehabilitation specialists as well as rheumatologists for the care of RA patients in Turkey. An alteration was made in the eighth recommendation on treatment of active RA patients with unfavorable prognostic indicators after failure of three conventional disease modifying anti-rheumatic drugs. Remaining principles were accepted as the same although some alterations were suggested but could not find adequate support to reach significance. Conclusion: Expert opinion of the TLAR for the treatment of RA was composed for practices in Turkish rheumatology and/or physical medicine and rehabilitation clinics