International Journal of Research in AYUSH and Pharmaceutical Sciences (IJRAPS)
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TRIVIDHI KARMA IN SURGERY (SHALY TANTRA)
Detailed description about surgical procedure was given by Acharya Sushrut. Purva Karma, Pradhan Karma, and Paschat Karma are Trividhi Karma. Shastra Chikitsa is one of the prime equipment in which Trividh Karma i.e. Purva Karma (Pre-operative), Pradhan Karama (Operative, main action) and Paschat Karma play a crucial role in order to get fruitful result after surgery. According to Sushrut, Purva Karma means preparation of the patient along with collecting all the materials during Pradhan Karma. Asthvidhishastra Karma is included in Pradhan Karma. Paschat Karma includes all post-operative care. Paschat Karma includes care after surgery i.e., post-operative care of the patient. Every surgery is done under these Trividh Karma so that there will be better outcome after surgery. Acharya Sushrut well known as father of surgery in Ayurveda selected these three Karma wholly and solely for the benefit of patients who undergo through any surgical procedure because surgery not only includes main action (operation) but also care of the patient before and after surgery. He has also emphasized that aseptic and antiseptic precautions should be taken. The wound should be protected from dangerous and invisible creatures. Every surgical procedure is done under these three parts only. Each Karma has got its own importance. We cannot skip any of them and it is very important in order to get good result. Acharya Sushrut also emphasised on diet which is given before and after any surgery. He also explained about septic and antiseptic precautions to be done before, during and after surgery. He also mentioned about fumigation of patients ward after 7-10 days of surgery
PHARMACOGNOSTIC STUDY OF MANSOA ALLIACEA LEAF
Mansoa alliacea Lam. (Family: Bignoniaceae) is a native plant from Amazonian basin in South America. Plant derivatives are used as anti-inflammatory, antioxidant, antiseptic and antibacterial agents. The study was aimed to determine the pharmacognostic and phytochemicals present in Mansoa alliacea. Micro and organoleptic characteristics of fresh and dried leaf samples had been examined. Physicochemical variables had been done by using WHO suggested variables; preliminary phytochemical of leaf sample had been performed to identify the presence of alkaloids, flavonoids, tannins and phenols, and quinones using the ethanolic extract of the leaves of M. alliacea
A CLINICAL EFFICACY OF VAITARANA VASTI ALONG WITH SIMHANADA GUGGULU AND RASNA SAPTAK KWATHA IN THE MANAGEMENT OF AMAVATA (RHEUMATOID ARTHRITIS)
Objectives: This study was conducted to evaluate the effectiveness of Vaitarana Vasti along with Simhanada Guggulu and Rasna Saptak Kwatha in the Management of Amavata (Rheumatoid Arthritis). Amavata is not only a disorder of locomotor system but is a systemic disease and is named after its chief pathogenic constituents i.e. Ama and Vata. The prolonged use of modern medicines shows some side effects and therefore an attempt was made to find an effective Ayurvedic treatment modality.
Methods: A single blind clinical trial was conducted at O.P.D. and I.P.D. of Post Graduate Department of Kayachikitsa, Ayurveda Mahavidyalaya Hospital, Hubli. Vaitarana Vasti was given in followed by Shamanoushadhi Simhanada Guggulu 500mg twice and Rasna Saptak Kwatha 40ml as Anupana for 45 days with 1 month follow-up period.
Results: Out of 15 Patients, 8 Patients (53.33%), 9 Patients (60%) falls under Marked Relief category of Grip strength and Tenderness respectively. 01 Subject (6.66%), 3 Patients (20%) falls under Moderate Relief category of Grip strength and Tenderness respectively. 06 Patients (40%), 2 Patients (13.33%), 12 Patients (80%) falls under Mild Relief category of Grip strength, Tenderness and E.S.R respectively. 1 subject (6.66%), 3 Patients (20%) falls under No Relief category of Tenderness and E.S.R respectively.
Conclusion: Vaitarana Vasti Along With Shamanoushadhi Shamanoushadhi Simhanada Guggulu and Rasna Saptak Kwatha was found to be highly effective in Amavata and showing a way out to the individual suffering from this Amavata (Rheumatoid arthritis)
AYURVEDIC MANAGEMENT OF MALE INFERTILITY (OLIGO ASTHENO TERATOZOOSPERMIA) DUE TO VARICOCELE; A SINGLE CASE STUDY
Male infertility is very commonly associated with Varicocele, which causes blood pooling, and it inhibits the production and quality of semen. Ayurveda offers a range of medical management opportunities, including Panchakarma chikitsa and Shaman Chikitsa. Viirechana helps to relieve testicular swelling. And other Shukra prasadaka, Shukra shodhaka and Shukrala dravyas have very good impact in the production and function of Shukra dhatu. A single case study has been successfully treated with absolute Ayurveda way of diagnosis and treatment
A CASE OF HAEMORRHAGIC OVARIAN CYST CURED WITH HOMOEOPATHIC SIMILIMUM
Haemorrhage in an ovarian cyst is very common. These cyst are known as haemorrhagic ovarian cysts (HOCs).Most of the cyst disappears spontaneously, but certain cyst requires surgical intervention. HOCs are formed because of occurrence of bleeding into a follicular or corpus luteum cyst. Allopathic system of medicines used various hormonal pills for its management which may have adverse drug reactions. Homoeopathic medicines are very helpful to manage such conditions. This article is about a case of 27 years old female who was suffering from haemorrhagic cyst. Homoeopathic medicine was given on the basis of totality of symptoms and patient cured within three months of treatment. Patient’s consent has been taken for the publication of this case report
MALNUTRITION-CHALLENGE IN 21ST CENTURY AND PROBABLE CONTRIBUTION OF AYURVEDA THROUGH MORINGA LEAVES
Nutritive diet has grabbed the center stage in current times among common men as well as researchers &food has turned into a whole damn industry. Despite of everything, Malnutrition is the largest single contributor to diseases in the world & leads to 45% of all deaths in children under 5 in developing countries. Due to interrelated mother- child nutrition, if a breastfeeding mother gets required nutrition, her kid becomes healthy. The causes of improper nutrition are variable but lack of nutritious food combinations in all classes are most important throughout the world.
Ayurveda is science of individualistic need based dietetics & nutrition and describes foods accordingly. There is recommendation of a super food named Shigru (Moringa) for Sutika (lactating mothers) in Bheshajyaratnawali,taking this as reference we have conceptualized a food combination of Moringa +wheat flour+ jaggery which is super nutritious and serves as a cheap, affordable, easy to collect and easy to make, palatable preparation.
When 11% of the world’s population is under nourished, need for such right food combination increases manifolds. Owing to per 100g nutritive value of these contents and their cost effectiveness, this combination has a potential to be a perfect staple dietary option for nutrition deficit individuals. It needs to be further established at large scale through RCTs so that large population can be benefitted
IMPORTANCE OF UPYANTRA IN SHALYA CHIKITSA
Ayurveda is considered as one of the best health science of ancient era. There are 8 branches of Ayureveda and Shalya chikitisa is the most important branch of Ayurveda due to its quick action (Ashukrye –Karnat). Shalya Chikitisa includes different surgical and para surgical technique which can be moulded depending upon the Immunity of Patients.
Today in modern scenario, where advance Science & technology is going to its highest peak & medical Science is becoming emphasis on knowledge of Upyantra seems quite obsolete. Sometime the situation arise when we don’t have proper medical facility during natural calamities where giving medical faculty to every person in not possible. To combat such disastrous situation the knowledge of accessory medical equipment is very important so, that we can survive. Acharya Sushrut is considered “Father of Surgery” who know how to overcome such situation with his unique power of thinking when situation is opposite for survival.
Acharya Dalhan, Acharaya Vagbatta, Achary Sushrut had explained different Yantra and Upyantra which can be used according to the patients immunity. In modern surgery there is no treatment option. They make patient to fit the available treatment but in ancient health science i.e., in Ayurved there are different way of treating patients depending upon their nature of body. Various types of Yantras used in Shalya Chikitsa includes Swastik Yantra, Taal Yantra samdansha Yantra, Shalaka Yantra, Naadia Yantra and Upayantra. These instruments place an at most role in the success of Shalya Chikitisa and without them the practical work of concept of Shalya Chikitisa cannot be made
ISOLATION OF ANTIBIOTIC PRODUCING BACTERIA FROM POND SOIL, GUDLAVALLERU
Soil being a major reservoir for microorganisms it is a source of interest for isolation of antibiotic producing organisms. The emergence of antibiotic resistance and need for better, broad spectrum antibiotics is always in high demand. In the present study, antibiotic producing bacteria were isolated from a local soil sample. Total ten soil samples were collected from local pond aseptically and subjected to serial dilution. Crowded plate technique was employed for the isolation of the colony. Total five isolated were isolated which exhibited zone of inhibition around the colony. The isolated colonies were subjected to morphological, microscopical and biochemical characterization. All five colonies were found to be gram positive, non-sporulating organisms and found they belong to the Actinobacteria class. The isolated colonies were subjected to screening for antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Yeast by perpendicular streak method. The primary screening results conclude that except one colony all have good antimicrobial activity. One colony found to be highly potential activity which had inhibition towards gram positive, gram negative, sporulating and fungal activity. This study may contribute in providing information on the antibiotic producing microorganisms in soil. Further characterization, purification, and structural elucidation are recommended to know the novelty, quality and commercial value of these antibiotics
DESIGN, SYNTHESIS AND MOLECULAR DOCKING STUDIES OF NOVEL N-SUBSTITUTED-2-(FURAN-3-YL)-1H-BENZIMIDAZOLE DERIVATIVES
Benzimidazole pharmacophore possess broad class of curative properties like anthelmintic, antiulcer, antihypertensive, anticancer, etc. In view of this reason benzimidazole derivatives synthesis gained vital significance in recent years. In this investigation, a series of novel substituted benzimidazole derivatives having furan appendage at 2nd position and alkyl/aryl appendage at 1st position were synthesized by using appropriate procedures. All the compounds synthesized were characterized by physically (Rf values, Melting point, Molecular weight, Molecular formula) and were characterized by spectral data (1H-NMR, 13C-NMR, IR and Mass spectra). All the synthesized compounds were screened for molecular docking studies on human gamma-tubulin protein to find out the binding interaction at the target active site. Molecular docking studies at human gamma-tubulin protein states that the compound 4b showed good binding affinity (-8.98 kcal/mol) in comparison to the reference compound Albendazole (-8.47 kcal/mol)
PHYTO-MEDICINAL EFFECTS OF SYZYGIUM CUMINI ON DIABETES: A REVIEW
Diabetes is a major public health problem which has been increasing day by day throughout the world with an alarming rate. In recent years, several plant extracts have been examined for their anti-diabetic properties to identify alternative treatment strategies that pose less risk for diabetes. It has been shown that different parts of these plants are collected from diverse regions and administered in different pharmaceutical preparations. The aim of the present review is to provide an overview of the phytochemicals present in S. cumini plants and their potent anti-diabetic activity, toxicological and biological effects of these plant extracts, their current state, limitation and future prospects in developing countries that are not included in the European Pharmacopoeia. In addition, a prospective research result of synergistic use of this plant with other plant (Ficus racemosa) done presently in our laboratory has been included. Based on the available evidence, we highlight the ways in which their therapeutic potential can be properly harnessed and provide scientific evidence for the discovery of novel leads for herbal drug development