International Journal of Research in AYUSH and Pharmaceutical Sciences (IJRAPS)
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DUPLICATION OF THUMB AT META CARPO PHALANGEAL JOINT IN RIGHT HAND OF 19 YEARS OLD BOY -A CASE REPORT
Get PDFHere reporting a case of bifurcation of right thumb in the form of beak like deformity on the right side in a 19 years old young male present since birth. This anomaly was coming in the way his normal activities like lifting heavy objects and while performing any purposeful movements like writing and while taking his bolus of food. There was definitely family history of different anomalies, but no history of systemic diseases running in the family. There was no other anomaly in him. Other fingers and toes were absolutely normal. Though this is common anomaly that is found in the society, it has profound developmental and Anthropological importance. Hence studied and reported
AYURVEDIC APPROACH OF DIABETIC FOOT ULCER
Get PDFDiabetes Mellitus is disease known from the dawn of civilization. Sedentary life style, lack of exercise, faulty dietary habits, improper medication and urbanization precipitate the disease. It is estimated that the total number of people with diabetes will rise from 171 million in 2000 to 366 million by 2030. Diabetic foot is one of the common complications of diabetes. Approximately 5-10% of all diabetics develop foot ulcer at least once in their time and more than 50% of non-traumatic amputations of lower limbs are foot complications in diabetic patients. Amputation of a part of lower limb is 15 times more common in diabetics as compares to general populations. In Ayurvedic text it is widely described by Acharya charak and Sushrut under Prameh pidika with its complication and treatment
PHARMACOGNOSTIC AND PRELIMINARY PHYTOCHEMICAL EVALUATION OF NELAMUCHCHALA (GYMNOSTACHYUM FEBRIFUGUM BENTH.)
Get PDFoai:ojs2.ijraps.in:article/1Folklore medicine is an integral part of Ayurveda. Nelamuchchala (Gymnostachyum febrifugum Benth) is one such drug which is traditionally used for fever, ulcers, Cough and metrorrhagia. Aim: The present study deals with Pharmacognostic, determination of Taste and preliminary Phytochemical investigations of root. Materials and Methods: The study includes microscopy, Physical analysis, determination of taste and preliminary phytochemical evaluation using methods given in Indian Ayurvedic Pharmacopoeia and Pharmacognosy by Dr. Khandelwal K.R. Results and Discussion: The microscopic structure of root shows as Polyarch vascular bundles, central large thick walled parenchymal pith and presence of calcium oxalate crystals in parenchymal cell of cortex. The preliminary phytochemical analysis revealed the presence of carbohydrates, flavanoids, phenol and steroids in various solvent extracts. The pH of the drug was 6.50. The ash analysis revealed the presence of fluoride, sulphate, chromate and aluminium. Tikta and Kashaya rasa determined by taste with tongue followed by ‘blind method’. Thin Layer Chromatography (TLC) was carried out after organising the appropriate solvent system, in which three spots of phenols were distinguished. The Rf value are 0.1702, 0.2638 and 0.5361. Conclusion: The result of the present study can be useful for the identification and preparation of a monograph of the plant. Observations could be considered to be the reference standards in future studies
ARECANUT (ARECA CATECHU L.) POLYPHENOL AS ANTI-VENOM: COMPILATION OF LITERATURE
No full textEnvenomation is a common public health problem in several countries, especially in rural areas. Though several synthetic anti venom drugs are available to treat poison bite patients, transportation of victims to hospitals, improper storage facilities of such drugs in rural areas are some of the hurdles in the management of such victims. Plants have rich source of phytochemicals with lots of medicinal properties. Such medicinal values are being used widely by traditional healers. Several researchers have now validated the ethnomedical properties of such plants with proper scientific data. Polyphenols of plants are known for anti-venom properties since very long time. Application of such knowledge might be very useful as first aid in the treatment of poison bites. The fruit of areca palm, Areca catechu L, commonly called as arecanut or betel nut is mostly chewed for its medicinal values. This medicinal plant also contain good amount of polyphenols (35 to 55%) in its nuts. However, very less research work has been done on the antivenom properties of this medicinal plant. Present review is focused on compiling such works by searching Google scholar, Pub Med, textbooks and old journals until June 2017 and urged the researchers for further detailed studies on these lines. It was reported that the aqueous extract of the seeds of arecanut was reported to inhibit the action of the venom of the monocellate cobra, Naja naja kaouthia. The medium effective dose of arecanut was reported to be 62.0µg/mouse. The necrotizing activity caused by the venom was also successfully inhibited by injecting arecanut extract at a dose of 30.0µg/mouse. Processed tender arecanuts, known as chikni supari were also reported to be effective in absorbing the venom from the bite wounds of scorpions, lizards and even snakes. This knowledge could be used as the basis for further detailed studies on the anti-venom properties of this plant
KSHEERBALA TAIL AND ITS DIFFERENT ROUTES OF ADMINISTRATION
Get PDFKsheerbala Tail having Shaman rasayana and Brimhana properties. The content of the tail adds to its effect. Ksheerbala tail having contents of Bala (Sida cordifolia), Goksheer (Cow’s milk), and Sesame oil (Sesamum indicum), it normalizes the Vata and Pitta in the body and shows anti-inflammatory action. It is also given in almost all Authentic books Charak Samhita, Ashtang Hridya and Sushrut, with different names. It acts as a nervine tonic and strengthens the muscles and to provide better options to Non-Steroidal Anti-inflammatory Drugs (NSAIDs). Non-steroidal anti- inflammatory drugs owing to its exceedingly speckled side effects and adversities are in the verge of a moribund reliance. Ksheerbala Tail, a sage old Ayurved remedy remarkably emphasised in the treatment of Vata Vyadhi and Vatarakta is well used since ages as an anti-inflammatory medicine. Developing researches have demonstrated its efficacy to counter neuro toxicity and subsequently validated its neuro protective effect. Though, the much acclaimed traditional wisdom regarding its anti inflammatory action is neither scientifically appraised nor compared with any standards. It is also used for Abhyang in detoxication process. Vata Vyadhi is best treated by Basti chikitsa, Abhyang etc. Matra basti is a type of Sneha basti which provides nutrition as well as pacify the morbid Vata dosha. In this article mode of action of Ksheerbala Tail and its different routes of administration are compiled
FORMULATION AND EVALUATION OF PARACETAMOL SUSPENSION BY USING NATURAL SUSPENDING AGENT EXTRACTED FROM BANANA PEELS
Get PDFThe present work was aimed to formulate and evaluate a new, cheap and effective natural suspending agent that can be used as an effective alternative for traditional suspending agent. The study procedure involved extraction of suspending agent from the Musa paradisica (Banana) fruit peels, determination of swelling index, phytochemical testing, Micromeritic properties of mucilage like Bulk density, Tapped density, Carr’s index, Hausner’s ratio, Angle of repose, Calibration of paracetamol, preparation of paracetamol suspensions and evaluated for pH determination, determination of sedimentation volume, redispersibility, determination of flow rate, measurement of viscosity, effect of temperature, drug content, particle size determination and In-vitro dissolution studies. The study showed that the extraction of suspending agent from banana fruit peels. The swelling index was found to be 40%. The photochemical test showed contains carbohydrates. As the concentration of suspending agent increases therefore viscosity of suspension increases which ultimately reduces the sedimentation of suspension
PHYSICOCHEMICAL STUDY OF A UNANI PHARMACOPOEAL TABLET ‘QURS-E-GULNAR’
Get PDFIn the Unani System of Medicine the drugs derived from natural sources are used, the majority of them are from plant origin. These single drugs are formulated in different dosage forms i.e. Tablets, Pills and Semisolids (Lauq, Khamira, Majoon etc.). Like any other system of medicine the efficacy of Unani formulations depends on potential and purity of the drugs used. To develop a mechanism for quality assurance of plants products and to ensure the purity of crude drugs and its standardization is essential. Standardization and quality control are the key factors in regulating the therapeutic efficacy because organoleptic parameters are insufficient for quality assessment. The present study deal with compound Unani formulation of Qurs-e-Gulnar a tablet formulated on the formullae mentioned in National Formulary of Unani Medicine Part I. For standardization of drugs, investigation of the tablets were made on the basis of the parameters approved by the Unani Pharmacopoea Committe, along with the analysis of pesticidal residue, microbial load, heavy metals and aflotoxin analysis. their percentage composition are as follow Total ash 22,89 %, Acid insoluble ash 21.72 %, Water soluble ash 1.39, Alcohol soluble matter 17.68 %, Water soluble matter 31.11%, , Water content 4.53%, pH 10%: 3.91 & 1%: 4.05, Disintegration time in pure water 30 second, Disintegration time in acid media 25 second, weight of qurs 500 mg and Diameter of qurs 10 mm is being determined and purity is confirmed. In addition analysis of Microbial Load, Aflatoxin and Pesticidal residue were also done but not detected The Thin layer chromatography (TLC) finger printing was made to check the standard of future batch
ATTRIBUTION OF AYURVEDIC HERBS IN MADHUMEHA
Get PDFNow a days people are facing life style disorders and stressful mental conditions due to the hectic and busy schedule. Madhumeha is one among them. It is the single most metabolic disease affecting the organ/system in the body. It is a burning problem in today’s scenario. It has been grouped under 20 Prameha described by our ancient Acharayas. This disease does not originate suddenly. Its pathophysiology takes long term. Any of Prameha neglected ends up in Madhumeha. It cannot be completely cured but can be prevented by food, medicines, life style etc. Administration of Ayurvedic herbs can play a very beneficial role in preventing this disease as well as its complication because they are oriented towards preventive and treatment approach. Various drugs of herbal origin as well as mineral origin is being mentioned in Ayurvedic texts Herbal medications shows anti diabetic effects and bring varying effects on the blood sugar level with minimal side effects. Role of herbs such as Ashwagandha, Haridra, Daruharidra, Aamlaki etc. in Pre diabetic, Diabetic and its complications along with effects of such herbs in experimental studies will be explored in present paper
PICRIC ACID; AN ALTERNATIVE SPECTROPHOTOMETRIC REAGENT FOR ESTIMATION OF EDTA SALTS
Get PDFThere are many reagents and techniques by which EDTA can be estimated in water as well as in Raw material. We standardized more quick and easy method for EDTA estimation. It has been reported that PA forms charge transfer complex with compounds. The stability of charge transfer complex depends upon the nature of compound, but mostly these are unstable. PA and EDTA complex show absorbance maximum at 450nm. The aim of our present study was to standardize an alternative method to estimate EDTA in water sample and in pure form by using the complex absorbance property at 450 nm. The 8,12,18,20 and 24 ppm concentration levels were prepared from standard stock solution of EDTA. PA of concentration 0.5gm in 100ml was prepared in chloroform. In each flask 1ml of PA was added and make up the volume of each flask with acetonitrile. The Standard plot was prepared by using EDTA -SALT and recorded Optical density at 450nm (Fig 01). The concentration level of PA was always high then EDTA-SALT in reaction mixture. However excess PA did not interfere at this wave length (450nm).
The EDTA alone Did not show any absorbance in the range of 220 – 400 nm, but EDTA-PA complex showed an absorbance maximum at 450nm(Fig-02).We also checked the necessary optimization factors time ,temperature and solvent effect, which are directly or indirectly effect the stability and formation of EDTA-PA complex. Stability study of complex with time, temperature and Solvent Effect are represented respectively in Fig 03, Fig 04 and Fig 05
EFFECT OF PRATISAARANEEYA APAMARGA KSHARA IN THE MANAGEMENT OF JALARBUDA W. S. R TO MUCOCELE OF LIP-A CASE STUDY
Get PDFJalarbuda is a water bubble like growth in lip caused due to vitiation of Vata and Kapha. Ksharakarma is one of the para-surgical procedures advised for management of Jalarbuda. This condition can be correlated to mucocele of lip. This is a case report of 22 year old man who presented with a small swelling in lip associated with discomfort since one month. In this study Pratisaaraneeya Apamarga Kshara is used in management of mucocele. The size of mucocele reduced after two days of Kshara application