International Journal of Ayurveda and Pharma Research
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Review on Plants Used in Siddha Formulation Vatha Siletpana Sura Kudineer for the Management of Viral Fever
Get PDFSiddhars said about various diseases and the treatment methods with herbs, minerals and animal products. In Siddha literatures viral fevers can be compared to Vatha Kapha Suram and therefore decoction for this Suram is taken from classical Siddha text book and the ingredients are searched for pharmacological activity and toxicity study from 118 published journal papers from Pubmed, Scopus, Google Scholar, Research Gate and Science Direct. Collected data is entered in MS excel and analysed using RFC score. All together there are 51 pharmacological activities are published for these nine ingredients. In which Anti-inflammatory has RFC=1, other properties like antipyretic, anti-tussive, bronchodialator, anti-asthmatic, analgesic, neuro-regenerative, neuroprotective, anti-diarrhoeal, anti-emetic, neuroprotective, analgesic, sedative has more than 0.55 RFC score. More than this cardioprotective, renoprotective, hepatoprotective, and other protective properties are present in more than 50% of ingredients. In toxicity studies no toxic effects are seen in in vivo studies for the ingredients The Suvai, Thanmai, Pirivu, in Siddha aspect, of these ingredients can highly reduces Vatha and Kapha disorders. Therefore, the decoction shows significant pharmacological activity for the sign and symptoms of viral infections
Role of Sthanik Chikitsa in Shweta Pradara Associated with Madhumeha (DM Type- II): A Case Study
Get PDFShweta Pradara or excessive vaginal discharge is one of the commonest complaints among women of reproductive age group. An increase in the normal vaginal secretion develops physiologically at puberty, at ovulation, premenstrual phase and during pregnancy. Excessive discharge causes irritation and itching in the genetalia. Ayurveda explained this condition as Shweta Pradara. Shweta Pradara is a symptom which is present in most of the diseases or present as a complication. Shweta Pradara is not a disease it produces as a symptom, hence etiopathogenesis of principal disease and Shweta Pradara would be same. It is a Kaphaja disorder at the place of Apana Vayu. A 47 years old female patient suffering from intermittent Yonigata Shwet Strava since two years with aggravation of symptoms from one week presented to Prasuti Tantra Evam Stree Roga OPD. Yonigat Shwet Strava was associated with Yoni Kandu, Katishool, Yoni Daha. On enquiry, it was found that she was the known case of Type II Diabetes Mellitus since 10 years. She was taking medication for the same but her blood sugar levels were uncontrolled in spite of taking medication as per her recent investigations. In this case Shwet Pradar was the Updrava of Madhumeh, thus line of management was planned to control her sugar level by supplementing Ayurvedic drugs along with allopathic medicine for DM II (Madhumeh) and treated her with Yoniprakshalan with Triphala Kwath followed by Cutis ointment tamponing per vaginum for 14 days. She had followed the schedule of Yoni Prakshalana, oral medicines and Pathya-Apathya properly. It was observed that, symptoms were started to reduce gradually which has been depicted by documentation of investigations and local examination in this case study
Pharmaceutico-Analytical and Antimicrobial Study of Amritank Rasa
Get PDFAmritank Rasa is a herbomineral formulation mentioned in the classical text of Basavrajiyam mainly used in the treatment of Pancha Kasa. This study aims to prepare the Amritank Rasa as per the classical text and conduct analytical and antimicrobial study of the prepared sample. The ingredients of Amritank Rasa are Kajjali, Trikatu, Pippalimoola, Chavya, Chitraka, Vatsanabha and Saindhava lavana all in equal parts and bhavana of Bhringaraj swarasa. The pharmaceutical procedure involves the preparation of Amritank Rasa vati in the 125mg dosage form. The pharmaceutical, analytical and antimicrobial parameters were compiled and data was recorded. The organoleptic parameters were, dark greyish in colour with pungent odour and taste, appearance was round and uncoated, and smooth in touch. The physiochemical parameters and quantitative parameters were, total ash was 5.5%, acid insoluble ash was 0.5% and loss on drying was 11.8%, average weight was 121mg, uniformity of weight test showed that all the tablets were not within the range of deviation from average weight, friability test was 0.51%, hardness was 5.3kg/cm2 and disintegration time test showed that any tablet did not dissolve in 60 minutes. The sample was then subjected to advanced analytical parameters i.e., FTIR, PSD, XRF and XRD. The antimicrobial study of Amritank rasa showed that it is effective against S.aureus, E.coli, P.aeruginosa and C. albicans. The development of the present study will serve as reference standards for Amritank Rasa formulation, quality control and clinical researc
Ayurvedic Approach to Secondary Infertility
Get PDFThe God has blessed the female with most valuable gift of motherhood mother is also called as “Janani\u27\u27 who give birth to child. A woman hood is never considered complete without achievement of motherhood. Infertility is a burning issue because today\u27s changing lifestyle and stress increases metabolic and hormonal disturbance as a result diabetes, PCOS, infertility. Our focus is, if a woman having normal anatomy of pelvic organ than she should conceive by natural way by Ayurvedic treatment because more side effect of ovulation induction and hormonal therapy. In Ayurveda Bandhyatva (infertility) mainly occurs vitiation of Vata and Kapha Dosha, in some case Pitta may involve. Fertility also depends on mental condition of couple as Charak says sound mind couple gets conceived easily. In this patient had also metabolic disturbance and stress, and ineffective endometrial receptiveness, so we choose Ashwagandha (Withania somnifera) as a anti-stress and normalize Vata and Kapha and Shatavari (Asparagus racemosa) for endometrial tonicity and Sthanik (endometrial) Pitta Shaman and Chandraprabha for Apana Vata (pelvic) disorder, balancing Tridosha and for Dhatvagni Deepan (better metabolism)
Ayurvedic Management of Dushta Vrana
Get PDFNon-healing ulcers are the most common problem encountered in clinics today. Ulcer is a discontinuity over the skin exhibiting loss of epidermis, dermis, and sometimes subcutaneous fat as well. In Ayurveda, Dushta vrana can be correlated with non-healing ulcers. Acharya Susrutha detailed Dushta Vrana in Chikitsa Sthana. It is characterized by symptoms like Durgandha (foul smell), Vedana (pain), Chirakali (chronicity), Utsangi (elevated), Atipooyasrava (pus discharge), Atigandha Vrana srava, etc. All these features can be observed in non-healing ulcers. This study explores the Ayurvedic management of Dushta vrana using the principles of the Agada Tantra. Methods: Medicines like Kottam thakaradi Kashaya, Parankipattai Tablet, Tarunabhaskaram Gulika, Jeevaraksha Gulika, Nimbadi Kashaya, and Thriphala Guggulu were used in the treatment course along with Virechana and Jalookavacharana. Keraleeya chikitsa grantha, like Prayoga samuchaya and Visha Vaidya jyotsnika, contains too many Yoga that can be used in the management of Dushta vrana. Results: Symptoms were assessed before and after treatment. Discharge, foul smell, pain, numbness, and wound size were considerably reduced. Conclusion: Special Yogas mentioned in the context of Agada Tantra are found to be effective in the management of Dushta vrana
Understanding Nutritional Disorders - A Comprehensive Analysis of Ayurvedic Concepts
Get PDFNutrition is a vital component of health at individual and community levels. Food system has changed dramatically after green revolution, but malnutrition still persists as a challenge. Coexistence of nutritional deficiency along with overweight and obesity is the double burden faced by most of the countries. Ayurveda explains nutrition, giving utmost importance to the state of individual, in a much customised manner. Conventionally the meaning of ‘Santarpana’ is understood as superfluity and ‘Apatarpana’ as deficiency. There are some inadequacies in this understanding. While examining the descriptions in Ayurvedic classics and comparing them with contemporary knowledge it is seen that Santarpana can lead to some deficiencies also. This understanding is very much important in present scenario. Nutritional disorder is not a single entity as far as Ayurveda is considered. It is spreading throughout a wide range of diseases, since Ahara is an essential component in the development of many diseases. Various kinds of nutritional deficiencies occur due to the impairment in Ahara parinamakara bhava, Ashtahara vidhi viseshayatana and Ahara vidhi vidhana. The primary and secondary causes of nutritional deficiency in modern science are mainly related to food and body respectively. But, for bringing out a better classification, this should be revised by including tertiary causes consisting of psychological factors and feeding habits
In-Vitro Experimental Study on the Anticoagulant Activity of Rakta Pravarthana Churna
Get PDFCoagulation disorders disrupt the delicate balance between clot formation and prevention. Various coagulopathies involve abnormal clotting as a manifestation. Rakta Pravarthana Churna (RPC) is an Ayurvedic formulation designed for external application during Rakta Mokshana to address Apravarthana or clotting tendencies. Aims & Objectives: The in-vitro study aims to evaluate its anticoagulant (thrombolytic) activity using blood samples from healthy human volunteers. Materials & Methods: The clot lysis activity of aqueous and alcohol extracts of Rakta Pravarthana churna at two different concentrations (5% & 20%) along with streptokinase as a positive control and distilled water and alcohol as a negative control was carried out. Results: The aqueous extracts showed clot lysis activity whereas alcoholic extracts did not exhibit evidently significant clot lysis. Discussion: In comparison with positive control (streptokinase), aqueous extract of RPC at 5% concentration showed 10.76% more clot lysis activity, aqueous extract of RPC at 20% concentration showed 14.31% more activity. Conclusion: Aqueous extracts of RPC promote clot dissolution, while alcoholic extracts displayed inhibitory effects. These findings show the complexity of Ayurvedic drug interactions with coagulation processes. The study contributes to the understanding of anticoagulation potential of RPC and its scope for potential therapeutic applications
Clinicopathological Evaluation of Pandu from Grahani Roga with special references to Haematological Parameters
Get PDFAyurveda means wisdom or knowledge of life, is the natural holistic system of medicine. The disease Grahani is signified by its nomenclature i.e., incomplete digestion, malabsorption and mal formation of stool. In Ayurveda, Grahani Roga (malabsorption syndrome) is a chronic disease of Annavaha srota (GI tract) vividly explained in our classics. Above the umbilical region Grahani is located, is the seat of Agni (digestive enzyme). Main function of Grahani is to hold undigested food and after digestion it releases the food through the sides of its lumen. But the main cause behind Grahani roga is poor digestive fire and Amadosa (products of impaired digestion and metabolism) as per Caraka Samhita. It is important symptoms are Sukta pakam (fermentation), Muhu baddha muhu dravam (alternate pass of hard and loose stool), Adhman (flatulence), Manasa sadanama (mental frustration) etc. In modern it is correlated to Mal-Absorption Syndrome (MAS). In Grahani Roga the Pittadhara kala fails to recognize the digested and undigested food, often release the undigested food towards small intestine. The insufficient digested food is unable to yield the required Poshak Rasa (plasma) for transformation of Rakta (blood). The person suffers from diminished blood in the system. Hence Grahani patients suffer from Pandu (anaemia). In this present study 60 cases of Grahani roga along with symptoms of Pandu were divided into two groups. Group A (30 patients) were treated with Bhunimba churna. Group B (30 patients) were treated with Pippali churna. The statistical analysis reveals that Bhunimba churna statistically more significant than Pippali churna in the management of Grahani roga and Pandu
A Pharmaceutical Study of Rodhradi Lepa
Get PDFRodhradi Lepa is a Tarunya Pitikahara Lepa from Gadanigraha Text. It contains Rodhra, Dhatri and Vacha as ingredients. Rodhradi Lepa is a medication applied externally on face (Mukhalepa) for treating Tarunya Pitika (acne). Rodhradi Lepa is in Churna form (powder) which should be mixed with water and applied on face. Preparation of the Churna and Lepa are explained in the Sharangdhara Samhita. In the present study, Churnas of Rodhra (Symplocos racemosa Roxb.), Dhatri (Phyllanthus emblica Linn) and Vacha (Acorus calamus Linn.) were prepared and homogenously mixed to prepare Rodhradi Lepa. Step by step pharmaceutical procedures were carried out according to classical reference and SOP. Loss during the process, total yield is noted. Pharmacological action of the Rodhradi Lepa is discussed In brief
Role of Ayurveda, Lifestyle Modification, and Panchakarma Therapy on Stabilization of Atherosclerotic Plaque in Known Coronary Artery Disease Patient
Get PDFAtherosclerois is a major health concern in India and imposes a significant burden on the population. The prevalence of risk factors such as hypertension, obesity, smoking and high cholesterol levels contribute to the rising incidence of atherosclerosis in the country. A 57-year-old male presented with primary complaints of chest pain and heaviness, left arm pain, upper back pain, jaw pain, dyspnea on exertion grade I, flatulence, gaseous distension, cervical pain, scapular region pain, shoulder pain, constipation, and insomnia. He also complained of postprandial angina New York Heart Association (NYHA) Class III. The patient was a photographer by profession and had a history of hypertension, diabetes mellitus, and coronary artery disease. On 29th February 2020, he underwent computed tomography (CT) coronary angiography at another clinic which revealed stenosis of the 3 main coronary arteries – more than 90% stenosis in mid left anterior descending artery (LAD), 80–90% stenosis in proximal left circumflex artery (LCx), and 80–90% stenosis in proximal right coronary artery (RCA). The patient was advised an Ayurveda-based low-carbohydrate high antioxidant diet of 1,000 calories daily for the first 12 weeks. This case report supports the relationship between an Ayurveda-based low-carbohydrate high antioxidant diet and atheroma regression in a high-risk coronary artery disease patient