International Journal of Ayurveda and Pharma Research
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Management of Yauvanapidika Through Shamanaushadhi
Full text linkThe face is universally recognized as an essential element of emotional expression and personal identification. The presence of acne can notably impact an individual’s self-esteem, especially in social interactions. In Ayurvedic literature, Yauvana Pidika, as described by various Acharyas, exhibit features similar to acne vulgaris. Yauvanapidika, due to its minimum causative factors, signs and symptoms and less severity is mentioned as one of the Kshudrarogas in Ayurveda Samhitas. A 23-year-old female patient who was apparently normal before six months developed multiple pus-filled acne on her forehead and both cheeks associated with pain and redness had consulted the outpatient department. She was having regular tea consumption twice a day, a mixed diet, and excess consumption of sugars, oily, and junk food. She consulted other contemporary medical systems as well, but didn’t find any relief. She was under Ayurvedic management for one month and felt very satisfied with the results. In this paper, successful management of this case with Shamana modalities is highlighted, which will be documented evidence for future case studies
Ayurvedic Management of Female Androgenetic Alopecia (Khalitya)
Full text linkAndrogenetic Alopecia (AGA), or pattern baldness, is a common form of non-scarring hair loss primarily affecting the scalp, with a higher incidence in males. Genetic, hormonal, and environmental factors contribute to its pathogenesis. AGA significantly impacts psychological well-being. Conventional treatments like minoxidil, finasteride, and corticosteroids offer temporary benefits but are associated with adverse effects and recurrence of symptoms, prompting the need for safer alternatives. Methods: A 32-year-old female presented in November 2024 with gradual vertex hair loss and a SALT score of 28%. She was treated for one month with Jalaukavacharana (leech therapy), external application of Shirolepa (herbal paste), and internal Rasayana (rejuvenative) medications. Result: By the end of treatment, the patient showed visible improvement in scalp condition and hair density, with the SALT score reducing to 12%. Discussion: The classical Ayurvedic approach effectively managed AGA by enhancing blood circulation and follicular nourishment, offering a safe and holistic alternative to modern therapies
The Ayurvedic Management in Graying of Hair
Full text linkPremature graying may be due to early depletion of melanocyte reservoir seeding potential owing to environmental factors, inflammation or psychological stress. Reactive oxygen species-mediated damage to mitochondrial and nuclear DNA with mutations with age and dysregulation of anti-oxidant mechanisms or pro/anti-apoptotic factors within the cells results in melanocytic aging. Ayurveda addresses canities as Palithya. Bhrajaka pitha is responsible for imparting natural colour to hair. Ayurveda classics mention it as Sirogatavyadhi (Caraka Samhita), Sirokapalagatavyadhi (Vagbhata) or Khudraroga (Sushruta Samhita). Case presentation: The patient was of age 28 years, female, unmarried moderately built with BMI 21.8, with history of PCOD and migraine. She had presented with greying of hair over vertex region of head. She was of Kaphapitha prakrthi with dietary habits including fast food, spicy food, pickles and mixed diet. She had stress due to work and due to going to work by scooter, she is prone to sunlight exposure and had a habit of helmet wearing. She was given internal medication of Guluchyathi kashayam, Usheerasavam and Chandraprabha vati. Then, she was given Vicharana snehapana with Mahathikthaka ghrta and done Shodhana with Avipathi choornam. Then the Bahya prayoga of Siropichu was done with Prapoundarikadi taila and Rasayana done with Agasthya rasayana. Conclusion: Guluchyathi kashayam, Usheerasavm and Chandraprabha caused balance of Agni in the body, they were Pithasamaka also. Mahatikthaka snehapana reduced dryness and brought Snighdada to the body. The accumulated imbalanced Pitha was eliminated from the body through Virechana by Avipathy choornam. After Shodana, external application as Siropichu with Prapoundarikadi taila which was Palithyahara, Pithahara and Keshya was done. Rasayana was given with Agasthya rasayana. The new hair growth was of black, there was an increase in hair growth and satisfactory reduction in hair fall. There was stress relief and overall coolness of body
The Role of Local Therapies in Maintaining ENT Health According to Ayurveda
Full text linkTo maintain the health of the individual along with the Tridoshas, Agni, Saptadhatu, Trimala has to be in synchronization with which the physiology of the individual runs normal. The Urdhwajatru Pradesh is the region in which Kapha Dosha is dominant. All the sensory organs lie in this region. Also, Shira Pradesh is most complex part in this region. The Shira i.e. brain controls all the body systems and all the centers for every activity lies in the brain. The supraclavicular region including the brain, sensory organs- viz., Netra, Karna, Nasa, Jivha, and Mukha, Danta, Gala, Manya, Skandha region comes under this Urdhwajatru terminology according to Ayurveda. The local therapies for Urdhwajatru Avayava can be used for preventive and therapeutic management according to the disease condition. It’s mode of action is depend on the nature of the drug used for the therapy and the structural tissue compliance. Also, it can be modified according to the the Ashthavidh Parikshya Bhava of the individual, Dashvidh Parikhsya Bhava for the specific disease in the individual as mentioned in Ayurveda. Aim- To study the importance of the local therapies in maintaining ENT health. Objectives- To study in detail the action of every local therapy which is beneficial for the management of ENT health. Material & Methods- Literature search from Ayurveda Samhitas to understand Rachana, Kriya and mode of action of local therapies in the Urdhwajatru Pradesh. Discussion- Benefits of the local therapies which can be done for prevention of ENT diseases and also can be modified conveniently to restore healthy life in daily routine. Conclusion- The ENT health can be enhanced by following local therapies, which will be helpful to balance Sthanik Dosha and improves Sthanik Bal
Exploring the Health Benefits and Therapeutic Uses of Amruthotharam Kashayam
Full text linkAmruthotharam kashayam, or Nagaradi Kashayam, is prepared with three herbal remedies; Haritaki (Terminalia chebula), Shunti (Zingiber officinale), and Guduchi (Tinospora cordifolia) in 6:4:2 ratio. This formulation has the potential to treat numerous diseases. Comparing to the other drugs, the proportion of Amritu is higher than Nagara and Harithaki, hence the name Amruthotharam Kashayam. In various diseases with different Anupanas it is highly beneficial. Amruthotharam kashayam is an amazing formulation mentioned under Kashaya Prayoga prakarana. Through the qualities of Rasapanchaka and the synergistic impact of ingredients, Amruthotharam Kashayam effectively reduces Ama and raises Agni. When used logically with the right Anupanas, Amruthotharam Kashayam produces amazing results for a wide range of illnesses. According to classical literature, its Anupana is Saindhava (rock salt) and Guda (jaggery). However, this Kashayam can be made more effective by combining it with other medications during preparation, as in Anaha and Gulma- with Hinguvachadi choornam. Because Hinguvachadi choornam is mentioned in both Agnimandya and Amadosha, it will have an additional effect. Since Amrithotharam Kashayam possesses the properties of Amapachana, it is strictly prohibited to be consumed with Ghrita. Avarti tailas are also contraindicated due to their Guruta (heaviness). In Ayurvedic treatment, Amruttotaram kashayam is frequently used as a stand-alone medication for a variety of ailments
Human Gut Microbiome in Health and Disease-An Ayurvedic Perspective
Full text linkThe human gut microbiome refers to the complex collection of trillions of microorganisms residing in the gastrointestinal tract, which play a crucial role in homeostasis and disease. Over the past few years, our understanding of the microbiome has evolved significantly, highlighting its impact on a wide range of physiological and pathological processes. This emerging knowledge has transformed health sciences, revealing the gut microbiome’s essential role in maintaining metabolic, immune and neurological health. In this context, Ayurveda, a traditional system of medicine originating in India, has long emphasized the importance of gut health. Ayurveda’s integrative approach of dietary guidelines, lifestyle modifications, treatments, and practices aimed at restoring balance within the body. The "Agni" (digestive fire) in Ayurvedic terms, is considered a central element of health. Ayurveda teaches that proper digestion is essential not only for physical well-being but also for mental clarity and emotional stability. Ayurveda offers supportive view into modern microbiome science by focusing on the balance of bodily humours (Doshas) and recommending specific herbs, probiotics, and prebiotics that can support gut health. In-depth analysis of Ayurvedic concepts and practices in line with the theory of microbiome proves that they are aimed at maintaining a balanced gut flora. As microbiome research continues to evolve, Ayurveda\u27s emphasis on individualized care, nurturing the gut microbiome and enhancing overall health
A Case Study on the Add-On Effect of Kesharadi Ghrita with Ferrous Ascorbate in the Management of Mridbhakshanjanya Pandu (Pica)
Full text linkMridbhakshanjanya Pandu, an Ayurvedic condition correlated with iron deficiency anemia due to pica, is a prevalent disorder in pediatric populations, particularly in low socioeconomic settings. This case study presents a 7-year-old male with symptoms including pallor, fatigue, and habitual consumption of non-nutritive substances like clay and wall putty. Clinical and laboratory investigations confirmed iron deficiency anemia. The child was treated with a combination of Kesharadi Ghrita, a classical Ayurvedic formulation known for its Pitta-pacifying and digestive-enhancing properties, along with conventional ferrous ascorbate therapy over a 45-day period. Outcomes were assessed through symptomatic improvement and hematological parameters including hemoglobin levels, MCV, and RDW-CV. Notable clinical improvements were observed- pallor reduced from moderate to mild, appetite normalized, and pica behavior ceased. Hemoglobin levels rose from 8.2gm/dL to 10.3gm/dL without any reported side effects. The therapeutic role of Kesharadi Ghrita may be attributed to its Agni Deepana (digestive stimulant), Krimighna (anthelmintic), and Rasa Dhatu Poshana (nutritive) properties, which possibly enhanced iron absorption and corrected the underlying pathology. This case supports the integrative use of Ayurvedic interventions in pediatric anemia and highlights the need for further studies to evaluate the broader applicability of Kesharadi Ghrita in similar clinical contexts
Evaluation of Acute Oral Toxicity of a Polyherbal Ayurvedic Formulation in Wistar Rats as per OECD 423
Full text linkThe present study systematically evaluated the acute oral toxicity profile of Amrith Noni Artho Plus - a polyherbal Ayurvedic formulation containing Morinda citrifolia (Noni), Vitex negundo (Nirgundi), Boswellia serrata (Shallaki), and Commiphora wightii (Guggulu) - in accordance with OECD Guideline 423. Twelve female Wistar rats were subjected to a stepwise testing protocol involving initial (Step 1) and confirmatory (Step 2) phases, with three animals per dose group receiving single oral administrations of either 300mg/kg or 2000mg/kg body weight (limit test dose) via gavage. The formulation was suspended in normal saline (10ml/kg) and administered following overnight fasting. Animals underwent intensive clinical monitoring at predefined intervals (10 min, 30 min, 1h, 2h, 4h, 6h) post-dosing followed by twice-daily observations for 14 days. No mortality or treatment-related clinical signs of toxicity (including behavioural alterations, neurological symptoms, or autonomic disturbances) were observed at any dose level. Body weight trajectories and food/water consumption patterns remained normal throughout the study period, with no statistically significant deviations from baseline (p > 0.05). Gross pathological examination upon termination revealed no abnormalities in vital organs (liver, kidneys, heart, and spleen), and organ-to-body weight ratios fell within normal physiological ranges. The absence of adverse effects at 2000mg/kg classifies this formulation as Category 5 ("unclassified") under the OECD Globally Harmonized System, indicating an exceptionally wide safety margin. This study demonstrates that Amrith Noni Artho Plus is safe at doses up to 2000mg/kg, supporting its non-toxic nature and potential for safe therapeutic use
Critical Appraisal of Lakshanaskandha of Bruhat-Tryaee with special reference to Pandu
Full text linkLakshanas (symptoms and signs) are the backbone of clinical practice, whether in the form of physiological or pathological condition, in context of diagnosis or treatment one need to rely on the manifested symptoms only. Here it is very much important to understand pathophysiology of Pandu in different given context to understand seriousness of the condition and to plan the treatment accordingly. Materials and Methods: Mainly Bruhattrayee i.e., Charaka Sahmita, Sushruta Sahmita and Ashtanga Hridaya with its well-known commentary was selected as main text and Pandu has been searched. Results: It appears 23 times in Charaka Samhita, 21 times in Sushruta Samhita, and 8 times in Ashtanga Hrudaya. In the context of clinical signs and symptoms, references to Pandu were identified as follows: 2 instances as Purvarupa, 12 as Rupa, 7 as Upadrava, 2 as Ariṣhṭa, and 29 instances categorized under miscellaneous references. Discussion: The therapeutic approach to Pandu Roga must be individualized and rooted in a comprehensive understanding of its Samprapti. The selection of treatment modalities should be based on the underlying aetiology. Conclusion: Each symptom has its own specific Samprapti. Different symptoms can arise from various mechanisms. To effectively address Pandu, it is crucial to evaluate the causative factors and pathogenesis and plan the treatment accordingly
Ayurvedic Management of a Large Cystic Thyroid Nodule
Full text linkA thyroid nodule is a very common palpable swelling in the thyroid gland. About 95% of thyroid nodules are benign in nature. Thyroid nodules require assessment using suitable diagnostic tests and imaging techniques. Any nodule greater than 1cm should be biopsied to check for malignancy. Thyroid nodules occur more frequently in women than men. Here, presenting a case of a lady with a large cystic thyroid nodule in the left lobe, managed under the outpatient department. She presented with rapidly increasing swelling in her neck associated with pressure symptoms and spasming of hands and legs for 4 days. She was prescribed a combination of Varanadi Kashaya, Punnarnavadi Kashaya, Kanchanara Guggulu, Chandraprabha Vati and Gokshura Choorna internally and Karutta Vattu for external application. By the first follow-up itself (after 10 days), the patient felt symptomatic relief. Investigations repeated after 50 days showed considerable change in the size of the cystic nodule. Similarly, there is cosmetic resolution of the swelling at the 50th day follow up which is evident from the photographs provided