International Journal of Ayurveda and Pharma Research
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Analytical Study of Brahmi Ghrtia: A Polyherbal Ayurvedic Compound
Get PDFBrahmi Ghrita was processed as per the process of Snehapaka procedure described in classics. It contained Brahmi (Bacopa monneri), Sunthi (Zingiber officinale), Maricha (Piper nigrum), Pippali (Piper longum), Shyama (Operculina turpethum), Trivrit (Operculina turpethum), Danti (Baliospermum montanum), Sankhpuspi (Convolvulus pluricaulis), Nrpadruma (Cassia fistula), Saptala (Euphorbia dracunculoides), and Vidanga (Embelia ribes), were mixed in Ghrita and heated for three hours at 110°C every day for three days. On the third day Ghrita was filtered to obtain the finished product. In this manner, three samples of Brahmi Ghrita were prepared. To understand the changes that occurred during the preparation, Brahmi Ghrita were analysed by using modern parameters such as acid value, saponification value, and so on. After the analysis, it was found that the Rancidity were absent in Brahmi Ghrita; acid values of Brahmi Ghrita were 1.81; the saponification values were 212.30; the iodine values were 39.17; the refractive index was 1.4590; the moisture were 0.12%; and the specific gravity were 0.9441 respectively. The present study revealed that, there was no significant variation in the analytical values among all three samples of Brahmi Ghrita. TLC was carried out after organizing appropriate solvent system in which maximum 6 spots were distinguished
Occupational Contact Dermatitis from Bhallataka Shodhana - A Case Based Insight Into Urushiol Toxicity
Get PDFThe nut known as "marking nut" and colloquially referred to as "Bhallataka" or "Bhilawa," Semecarpus Anacardium Linn (Family: Anacardiaceae), has been utilized in traditional medicine systems for a variety of illnesses since ancient times. According to the Drug and Cosmetic Act of 1940, it is classified as a Schedule E 1 medicine (poisonous medicinal plant). Despite used for numerous health conditions in Indian medicine and traditional medicine as a single formulation and compound formulation. The sticky, tar-like oil found in Bhallataka has been linked to contact dermatitis, primarily due to the presence of urushiol- a compound known to cause blistering on areas of skin that come into contact with it. This irritant oil, located mainly in the pericarp of the fruit, contains a mixture of 3-n-pentadec(en)yl catechols, which include anacardic acid and the bioactive constituents bhilawanol A and B. Bhilawanol itself is a blend of cis and trans isomers of ursuhenol and is chiefly concentrated within the fruit. This paper presents a case report of allergic contact dermatitis resulting from exposure to vapors released during the Swedana process of Bhallataka fruit in a Dola Yantra. The condition was aggravated by negligent handling during fruit slicing, insufficient safety measures, and improper cleaning of utensils used throughout the Shodhana procedure. The Shodhana, Shamana and Raktamokshana by Siravyadha methods given was successful in reducing the symptoms. This case study demonstrates the efficacy of Ayurvedic treatment (Shodhana, Shamana and Siravedhana) in contact dermatitis
Krishna’s® She Care Ayurvedic Juice: A Literature-Based Review of its Polyherbal Approach to Women’s Hormonal Balance
Get PDFKrishna’s® She Care Juice is a polyherbal preparation that is intended to promote women\u27s reproductive health, especially in the management of conditions such as Polycystic Ovary Syndrome (PCOS), irregular menstrual cycles, dysmenorrhea, and other gynecological disorders. This review summarizes the existing scientific and clinical literature regarding the major herbal constituents of the product i.e., Saraca asoca, Berberis aristata, Zingiber officinale, and Triphala emphasizing their unique roles in modifying hormonal equilibrium, anti-inflammatory actions, uterine health promotion, and enhancing metabolic indices. Clinical trials of S. asoca establish its effectiveness in curtailing menstrual bleeding and dysmenorrhea. B. aristata demonstrated insulin-sensitizing activity, useful in the management of PCOS, while Z. officinale has evidence based on randomized controlled trials for its analgesic and hormone-modulating action. Triphala, exhibiting antioxidant and adaptogenic activities, proved useful in the control of menstrual disorders, Premenstrual syndrome (PMS), and endometriosis. While encouraging evidence exists for each of these individual herbs, a major gap still exists in direct clinical evidence comparing the safety, tolerability, and efficacy of the combination formulation as it occurs in Krishna’s® She Care Juice. This serves to underscore the imperative need for pre-clinical mechanistic studies and rigorously designed clinical trials to establish its therapeutic merits, refine dosing regimens, and define safety profiles. The novel traditional application and corroborative findings on its components render Krishna’s® She Care Juice an interesting subject for future investigation, with the potential to become a standardized, evidence-based Ayurvedic treatment for women\u27s health
Anti-Inflammatory Potential of Punarnavadi Churna- A Polyherbal Formulation
Get PDFPunarnavadi Churna is a polyherbal Ayurvedic medicine traditionally used in the treatment of abdominal diseases (Udar roga), oedema (Shotha) and ulcer (Vran roga). This study investigates the potential use of Punarnavadi Churna in managing inflammation through its key herbal ingredients, which include Punarnava (Boerhavia diffusa), Haridra (Curcuma longa), Daruhaldi (Berberis aristata), Devdaru (Cedrus deodara), Haritaki (Terminalia chebula), and Kantakari (Solanum surratense). These herbs are known for their potent anti-inflammatory properties due to the presence of active compounds that target inflammatory pathways. The primary anti-inflammatory mechanism of Punarnavadi Churna is its ability to inhibit pro-inflammatory cytokines and reduce oxidative stress, both of which play a significant role in inflammatory conditions. For example, Punarnava (Boerhavia diffusa) is known for its diuretic and anti-inflammatory effects, which helps to reduce inflammation and fluid retention. Haridra (Curcuma longa) contains curcumin, a powerful anti-inflammatory and antioxidant potential that has been studied a lot for its ability to reduce chronic inflammation. Other herbs such as Daruhaldi (Barberis aristata) and Devdaru (Cedrus deodara) also contribute to the ability of pain and inflammation. Research, which includes animal studies and clinical observations, has verified that Punarnavadi Churna is powerful in dealing with inflammatory conditions like arthritis and edema. The synergistic potential of these herbs complements their healing advantages, making Punarnavadi Churna a promising alternative in integrative fitness practices. Its ability to address multiple pathways of inflammation makes it a valuable natural treatment, supporting overall health and wellness through holistic, plant-based remedies
Ayurvedic and Yogic Intervention for Non-Alcoholic Fatty Liver Disease Reversal (NAFLD)
Get PDFNon-Alcoholic Fatty Liver Disease (NAFLD) is a progressive liver disorder characterized by excessive fat accumulation, inflammation, and fibrosis, often associated with metabolic conditions like obesity, diabetes, and dyslipidemia. Conventional treatments focus on lifestyle modifications and pharmacological interventions but may not effectively halt disease progression. Ayurveda considers NAFLD as a disorder of Medoroga and Yakrit Vikara, primarily caused by Agni Dushti and imbalanced Kapha-Pitta dosha, leading to impaired lipid metabolism. Ayurvedic management emphasizes Shodhana (detoxification), Deepana-Pachana (digestive stimulants), Yakrit Uttejaka (hepatostimulants), and Rasayana (rejuvenation therapy), along with dietary modifications and lifestyle interventions. Yoga therapy, including Asana, Pranayama, and meditation, supports liver detoxification, enhances digestion, and improves metabolic function. This case study presents the successful management of NAFLD in a middle-aged patient through a combination of Ayurvedic therapies and Yoga. Outcome assessment was based on improvements in liver function tests, lipid profile, glycemic control, symptom relief, and ultrasound findings over an 8-week treatment period. The results suggest that an integrative approach incorporating Ayurveda and Yoga can provide effective, sustainable management of NAFLD, potentially preventing its progression to severe liver conditions
A Comparative Standard Manufacturing procedure of Swarjika Kshara prepared from Ushtrapriya (Fagonia cretica Linn.) and Rudanti (Cressa cretica Linn.)
Get PDFSwarjika Kshara is a significant alkaline formulation in Ayurveda, traditionally prepared using plants like Ushtrapriya (Fagonia cretica Linn.) and Rudanti (Cressa cretica Linn.). Classical references such as Rasatarangini and Ayurvediya Rasashastra describe the preparation of Kshara, while modern practices often substitute it with chemically synthesized sodium bicarbonate. The Ayurvedic Pharmacopeia of India (API) lacks specific standards for plant-origin Swarjika Kshara, necessitating a study to develop and standardize its manufacturing process. Aim: To develop a Standard Manufacturing Procedure (SMP) for Swarjika Kshara prepared from Ushtrapriya and Rudanti. Material and Methods: Three batches of Swarjika Kshara were prepared from Ushtrapriya and Rudanti following classical references. Pharmaceutical observations were recorded, and standardized batches were produced to validate uniformity. Yield percentages, ash content, and procedural differences were analyzed. Results: The study found significant differences in yield, with Rudanti (47.41%) producing more than double the Kshara compared to Ushtrapriya (18.46%). Both samples were successfully standardized, and uniform operative procedures were established. Conclusion: The study validated SMP for Swarjika Kshara from Ushtrapriya and Rudanti, ensuring consistency in production. The findings offer a foundation for large-scale manufacturing and future research, addressing the gap in API standards for plant-origin Swarjika Kshara
Management of Pyogenic Granuloma on Eyelid through Chemical Cauterization (Kshara Karma)
Get PDFPyogenic granuloma is an acquired benign vascular proliferation. Clinical features are rapid painless, red polypoid papule or nodule growth on skin or mucus. Both surgical and non-surgical treatments are advised for pyogenic granuloma. Arsha vartma is one among Netraroga explained in Vartmagataroga’s according to Acharya Sushruta Arsha vartma tridoshaja chedana Sadhya vyadhi, is characterized by the eruption of a small, rough, lesion in lid margin which resembles Ervaru beeja (size of the lesion is similar to Cucumber Melos seed) and mild pain. Acharya Vagbhata included few other clinical features like burning sensation, bleeding and cure even after removal. Objective: to see the effect of Tilanala kshara in pyogenic granuloma. Methods: A 32 years old male patient visited our OPD of Shalakya Tantra, SJGAMC, Koppal, with complaints of painless slow growing mass on right upper eyelid near lid margin, occasionally bleeding with trauma since 20 days. Patient was diagnosed as Pyogenic granuloma (Arsha vartma). Patient was treated with 1 sitting of Tilanala Kshara Pratisarana and Jathyadhi ghrita ointment for 7 days. Result: complete resolution of pyogenic granuloma was seen in 7 days Conclusion: Chedana, Bhedana, Lekhana Dahana karma of kshara have effect on pyogenic granuloma and prevent the recurrence
Arishta Lakshanas - A Retrospective Pilot Study Among Nurses Working In Critical Care
Get PDFLife according to Ayurveda is considered as the Samyoga (combination) of Sarira (body), Indriya (sense organs), Satwa (mind) and Atma (soul). Among them Indriya refers to Arishta according to Charaka. Indriya Sthana states the relevance and importance of knowing Aristhta lakshanas before going to treatment. Arishta means, it is the state in which it has transcended all the remedial measures and widespread all over the body by the aggravation of Tridoshas. It is important in prognostication process, to prognosticate remaining survival time, in proper clinical decision making, to analyze the role and potential of Arishta Lakshanas in contemporary clinical prognostication, it helps to decide which patient to treat and which not to treat, whom to give palliative treatment and whom to give intervention treatment and helps to approach death with understanding and ease. Objective: To document perceptions, observations and experiences of nurses working in critical care on manifestation of Arishta Lakshanas in dying patients. Method: Survey study (77 nurses from different hospitals in state, national and international level was contacted and an online survey via Google forms was conducted). Results: Some of the changes in the parameters have been observed by the nurses in dying patients. Conclusion: Without Arishta Lakshanas no death occurs. So here an effort has been made to document the Arishta Lakshanas based upon some factors among the forty-eight examination factors of Aayu or Arishta stated in Indriya Sthana
An Ayurvedic Approach in the Management of Hirayama Disease
Get PDFHirayama disease is a self limiting condition affecting the motor component of distal upper limbs without any sensory impairment. It mainly affects young males of Southeast Asia with an increased prevalence in India and Japan. Clinical findings and Diagnosis: A 32 year old male patient approached the OPD with a known case of Hirayama disease for the past 5 years. By analyzing the condition and Dosha involved Ayurvedic treatment, both internal medication and external treatments were developed. Outcome: After a course of 28 days treatment divided into 9 and 19 days with a gap of 1 week, the patient showed significant improvement in the clinical signs and symptoms. Conclusion: Hirayama disease can be correlated to Vatavyadhi spectrum disorders like Bahusosha (a Vataja nanatmaja vyadhi). The main aim of treatment is to relieve the vitiated Vata and nourish the depleted Mamsa dhatu
Pharmaceutical Preparation of Prabhkara Vati - An Ayurvedic Formulation
Get PDFPrabhakara Vati, an Ayurvedic formulation, plays a significant role in treating heart-related ailments, as emphasized in the Bhaishajya Ratnavali (Hridroga Prakarana) and the Ayurvedic Formulary of India (Part 1). The preparation involves five key ingredients: Sudha Abraka Bhasma, Sudha Loha Bhasma, Sudha Swarna Makshika Bhasma, Sudha Shilajathu, and Tugaksheeri (Bamboo Manna). The preparation involves using Terminalia arjuna bark decoction during trituration (Bhavana), which enhances its medicinal properties and supports its cardioprotective function. The preparation of Prabhakara vati involves preprocessing of Abraka Bhasma, Loha Bhasma, Swarna Makshika Bhasma, and Shilajit Sodhana, each performed according to classical Ayurvedic methods. Each Bhasma was prepared by purification (Sodhana) process followed by incineration (Marana). Purification of Abraka, Loha, and Swarnamakshika was carried out by Nirvapa (quenching) method while Shilajthu sodhana by Suryatapi method mentioned in Rasataragini. After purification, incineration was done for each ingredient based on classical reference: 5 Puta (incineration) for Abraka bhasma, 8 Puta for Loha basma, and 6 Puta for Swarna makshika. Subsequently, Bhasma pareeksha was carried out to test the quality of each Bhasma. After the preprocessing of this Bhasma, Prabhakara vati was prepared by triturating an equal amount of each five ingredients with Arjuna kashaya, which was prepared using Bhavana method. Special care is taken to maintain the purity and authenticity of ingredients, ensuring the formulation retains its therapeutic efficacy. This work is a comprehensive documentation of the step-by-step preparation of Prabhakara Vati, conducted at Government Ayurveda College in Thiruvananthapuram, and provides a detailed guideline for the formulation process described herein