Procter & Gamble (United Kingdom)

Veterinar - Repository of the Faculty of Veterinary Medicine
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    5141 research outputs found

    Modern diagnostic and therapy standards in rodents, rabbits and African pygmy hedgehogs

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    Konstantna naučna istraživanja i usavršavanja dijagnostike, terapije i hirurških metoda rezultirali su, tokom prethodnih godina, kako produžetkom očekivanog životnog veka, tako i poboljšanjem kvaliteta života egzotičnih kućnih ljubimaca. Uzimanje temeljne i sveobuhvatne anamneze od vlasnika kunića (Oryctolagus cuniculus), glodara (ordo Rodentia) ili afričkih patuljastih ježeva (Atelerix albiventris) je od velikog značaja, kako mnogobrojna patološka stanja ovih životinja nastaju usled grešaka u držanju. Potpun klinički pregled zahteva od veterinara poznavanje metoda fiksiranja, mogućnost izvođenja specijalističkih dijagnostičkih metoda i prikupljanja uzoraka, ali i razumevanje morfoloških i fizioloških specifičnosti navedenih vrsta, te najčešćih zdravstvenih problema s kojima se suočavaju. Dodatno, pravilna primena analgezije i poznavanje savremenih anestetičkih protokola značajno unapređuju standard nege i uspešnost samog lečenja. Zaključno, savremeni standardi dijagnostike i terapije egzotičnih ljubimaca postavljaju nove izazove, ali i pružaju izuzetne mogućnosti za unapređenje njihovog zdravlja i dobrobiti.Continuous scientific research and advancements in diagnostic, therapeutic, and surgical methods have, in recent years, led to both greater lifespan and an improvement in the quality of life of exotic pets. Obtaining a thorough and comprehensive patient history from the owners of rabbits (Oryctolagus cuniculus), rodents (Rodentia), or African pygmy hedgehogs (Atelerix albiventris) is of great importance, as numerous pathological conditions may be a consequence of improper care and husbandry practices. A complete clinical examination requires veterinarians and technicians to be proficient in handling and restraint techniques, capable of performing specialized diagnostic procedures and sample collection, and knowledgeable about small mammals’ unique morphological and physiological characteristics. Furthermore, the proper application of analgesia and familiarity with modern anesthetic protocols significantly enhance the standard of care and the success of treatment outcomes. In conclusion, contemporary standards in the diagnostics and treatment of exotic pets present new challenges but also offer remarkable opportunities for improving their health and overall well-being.Zbornik predavanj

    Genetic diversity and adaptability of native sheep breeds from different climatic zones

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    To better understand the genetic architecture and adaptability of native sheep, 22 breeds were genotyped using ovine50K SNP chips. Eleven additional populations from open-source repositories were included. Cross population Extended Haplotype Homozygosity (XP-EHH) and Relative Scaled Haplotype Homozygosity (Rsb) haplotype-based approaches were used to identify genetic variations influencing the adaptation of local sheep breeds to different climatic zones. The results indicate that all breeds exhibited high but declining genetic diversity levels, with a larger proportion of genetic variation explained by development history and refined by geographical origin, as shown by principal component analysis and Neighbor Net graphs. Admixture analysis revealed high admixture levels in European and North African breeds. Using XP-EHH and Rsb methods, 371 genes were putatively under selection, with only nine common among all population pairs, highlighting unique adaptability. Most identified genes, including Interleukin (IL) and cluster differentiation (CD) gene families underlie immune responses, emphasizing their role in resilience to climate change effects. These findings support that indigenous sheep breeds have retained significant genetic diversity, but improper genetic management may threaten it. Additionally, the research emphasizes that indigenous sheep breeds’ unique adaptability to specific climatic zones makes them valuable genetic assets for developing climate-resilient breeds

    Animal respiratory viruses with zoonotic potential

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    Respiratory viruses of animal origin pose a major public health risk due to their ability to cross species barriers and cause zoonotic infections. Influenza A viruses, especially those from avian and swine hosts, have driven several human pandemics. Their segmented genome enables genetic reassortment, leading to antigenic shifts and the emergence of novel human-infecting strains. Swine act as "mixing vessels" for avian, human, and swine influenza viruses, increasing pandemic risk. Similarly, HPAI H5N1 causes sporadic, often fatal human infections linked to contact with infected poultry. Coronaviruses such as SARS-CoV, MERS-CoV, and SARS-CoV-2 likely originate from bats, with spillovers involving intermediate hosts like civets or camels. SARS-CoV-2, probably arising from a wildlife market, sparked a global pandemic with severe health and socio-economic effects. These events highlight the need for animal surveillance, viral evolution research, and a One Health approach to prevention and control.Book of abstract

    Review of the microbiological status of drinking water originating from poultry farms in the period 2015-2024

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    Вода која се користи у производњи хране животињског поријекла мора по свом квалитету, укључујући и микробиолошку безбједност, да испуњава услове који се односе на воду за пиће намијењену за људску употребу. На здравље животиња, између осталог, може значајно да утиче и вода за пиће коју животиње свакодневно конзумирају. Обезбјеђење безбједне и квалитетне воде кључно је у очувању здравља једин- ке. Најосјетљивија категорија су младе и високопродуктивне животиње. Вода је есенцијална храњива материја, посебно важна у развоју бројлерских пилића, који је конзумирају у великим количинама. До- ступност и квалитет воде играју значајну улогу у укупном здрављу и продуктивности живине. Међу- тим, обезбјеђивање безбједне и квалитетне воде у великој мјери се занемарује, при чему микробна кон- таминација воде угрожава опште здравље и производне перформансе живине. Истраживање је вршено у периоду 2015-2024. година и обухвата 2.641 узорак воде поријеклом са жи- винарских фарми, првенствено бројлерских пилића. Од анализираних узорака, посматрајући по катего- ријама, 59,23% је водоводска, а 40,77% бунарска и изворска вода. Циљ истраживања је утврђивање и процјена микробиолошког статуса воде за пиће поријеклом са живи- нарских фарми. Лабораторијско испитивање вршено је методама BAS EN ISO 6222, BAS EN ISO 9308-1 и BAS EN ISO 7899-2. Процјена микробиолошког статуса вршена је у односу на важећу регулативу (Служ- бени гласник Републике Српске 88/17, 97/18, 93/23, Прилог 1) и Правилник о здравственој исправности воде за пиће (Службени гласник Босне и Херцеговине 40/10, 43/10, 30/12, 62/17, Анекс I и Анекс II)). Микробиолошким испитивањем утврђено је 71,30% задовољавајућих и 28,70% незадовољавајућих узо- рака воде за пиће. У односу на категорију, утврђено је 83,49% задовољавајућих и 16,51% незадовоља- вајућих узорака водоводске воде, као и 49,36% задовољавајућих и 50,04% незадовољавајућих узорака бунарске и изворске воде. Узорци су били незадовољавајући због повећаног укупног броја микроорга- низама на 22°C (26,62%), повећаног укупног броја микроорганизама на 37°C (28,60%), цријевних енте- рокока (22,58%), Escherichia coli (18,09%) и колиформа (20,49%). Вода за пиће на живинарским фармама има веома неповољан микробиолошки статус, посебно са ста- новишта негативног утицаја патогених бактерија. Посебно забрињавајућа чињеница је висок удио бу- нарске и изворске воде, од којих је значајан број микробиолошки неприхватљив. Неопходно је преис- питивање, значајно побољшање и досљедно спровођење поступка дезинфекције воде, као и редован микробиолошки мониторинг.Water used in the production of food of animal origin must meet the requirements for drinking water intended for human consumption in terms of quality, including microbiological safety. Animal health, among other things, can be significantly affected by the drinking water that animals consume on a daily basis. Providing safe and high-quality water is crucial for maintaining the health of the individual. The most sensitive category is young and highly productive animals. Water is an essential nutrient, especially important in the growth of broiler chickens, which consume it in large quantities. The availability and quality of water play a significant role in the overall health and productivity of poultry. However, providing safe and high-quality water is largely neglected, with microbial contamination of water endangering the general health and production performance of poultry. The research was conducted in the period 2015-2024 and included 2,641 water samples originating from poultry farms, primarily broiler chickens. Of the analyzed samples, by category, 59.23% was water from the water supply sistem, and 40.77% was well and spring water. The aim of the research is to determine and assess the microbiological status of drinking water originating from poultry farms. Laboratory testing was performed using the BAS EN ISO 6222, BAS EN ISO 9308-1 and BAS EN ISO 7899-2 methods. The assessment of the microbiological status was carried out in relation to the applicable regulations (Official Gazette of the Republic of Srpska 88/17, 97/18, 93/23, Annex 1) and the Regulation on the health quality of drinking water (Official Gazette of Bosnia and Herzegovina 40/10, 43/10, 30/12, 62/17, Annex I and Annex II)). Microbiological testing determined 71.30% satisfactory and 28.70% unsatisfactory drinking water samples. In relation to the category, 83.49% satisfactory and 16.51% unsatisfactory tap water samples were determined, as well as 49.36% satisfactory and 50.04% unsatisfactory well and spring water samples. The samples were unsatisfactory due to an increased total number of microorganisms at 22°C (26.62%), an increased total number of microorganisms at 37°C (28.60%), intestinal enterococci (22.58%), Escherichia coli (18.09%) and coliforms (20.49%). Drinking water on poultry farms has a very unfavorable microbiological status, especially from the point of view of the negative impact of pathogenic bacteria. A particularly worrying fact is the high proportion of well and spring water, a significant amount of which is microbiologically unacceptable. It is necessary to review, significantly improve and consistently implement the water disinfection process, as well as regular microbiological monitoring.Zbornik sažetak

    Antimicrobial resistance in diverse ecological niches—One Health perspective and food safety

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    Antimicrobial resistance (AMR) is a multi-sectoral, systemic, and global issue worldwide. Antimicrobial use (AMU) is a key factor in the selection of resistant bacteria within different ecological niches, from agriculture to food-producing animals to humans. There is a question regarding the extent to which the use of antibiotics in livestock production and the primary food production sector influences the selection and transmission of resistant bacteria and/or resistant genes throughout the food chain and thus contributes to the complexity in the development of AMR in humans. Although the trends in the prevalence of foodborne pathogens have changed over time, the burden of ecological niches with resistance genes, primarily in commensal microorganisms, is of concern. The implementation of the harmonized surveillance of AMU and AMR would provide comprehensive insights into the actual status of resistance and further interventions leading to its reduction. Tracking AMR in different ecological niches by applying advanced genomebased techniques and developing shared AMR data repositories would strengthen the One Health concept

    Use of modern nutritional strategies with the aim of achieving optimal health status and maximum production results of broilers and laying hens in the concept of green agenda

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    Eubiotički odnosi u digestivnom traktu brojlera predstavljaju jedan od najvažnijih preduslova za očuvanje zdravstvenog stanja, a time i za poboljšanje proizvodnih rezultata životinja. Stres, poremećaji varenja i nagle promene obroka samo su neki od faktora koji remete ravnotežu i favorizuju nepoželjnu mikrofloru.. Zbog sve većih zahteva svetskog potrošačkog lobija, a poštujući proizvodne prioritete (bolje iskorisćavanje hrane, duža održivost, lakša manipulacija) sa konačnim ciljem povećanja proizvodnje i poboljšanja kvaliteta namirnica animalnog porekla, pored osnovnih hraniva u smeše se dodaje i veliki broj aditiva koji imaju različite namene. Dodatkom antiobiotika kao aditiva, proizvođači su u prošlosti ostvarivali dobit koja se zasnivala na većem prirastu uz bolju konverziju i niže troškove lečenja. Uporedo sa povećanjem količine utrošenog antibiotika primećen je globalni problem porasta učestalosti rezistencije bakterija na antibiotike. Takođe, utvrđeno je prisustvo rezidua antibiotika u namirnicama animalnog porekla, kao i njihovo moguće genotoksično delovanje. Nakon zabrane upotrebe antibiotika u svrhu stimulacije rasta, javio se interes za razvijanje novih nutritivnih strategija koje će podržati funkciju autohtone mikroflore u gastrointestinalnom traktu u kontroli patogenih bakterija. Jedinstvenom kombinacijom sastojaka, na Katedri za ishranu i botaniku kreiran je dodatak koji omogućava održavanje eubiotičkih odnosa (ravnoteža u mikropopulaciji digestivnog trakta) čime se povećava efikasnost varenja i resorpcije hranljivih materija (bolja svarljivost osnovnih hranljivih materija koja smanjuje produkciju amonijaka i ugljen dioksida), kao i otpornost prema poremećajima izazvanim enteropatogenim bakterijama. S obzirom na bolje iskorišćavanje hrane, opisanom nutritivnom strategijom dobija se veća telesna masa brojlera, bolji prirast, kao i niža konverzija.Eubiotic relationships in digestive tract of broiler is one of the most important prerequisites for preserving the health of animals, and thus for increasing the production results. Stress, digestive disorders and sudden meal changes are just some of the factors that disturb the balance and favor undesirable microflora. Due to the increasing demands of the global consumer lobby, and respecting the production priorities (better feed utilisation, longer sustainability, easier manipulation) with the ultimate aim of increasing production and improving the quality of foods of animal origin, in addition to the basic nutrients, a large number of additives with different purposes are added to the mixtures. By adding antibiotics as additives, producers in the past made profits based on higher growth with better conversion and lower treatment costs. Along with the increase in the amount of antibiotics used, the global problem of the increase in the frequency of bacterial resistance to antibiotics has been observed. Also, the presence of antibiotic residues in foods of animal origin, as well as their possible genotoxic effect, was determined. After the ban on the use of antibiotics for the purpose of growth stimulation, there has been an interest in developing new nutritional strategies that will support the function of indigenous microflora in the gastrointestinal tract in the control of pathogenic bacteria. With a unique combination of ingredients, the Department of Animal Nutrition and Botany created a supplement that enables the maintenance of eubiotic relationships (balance in the micropopulation of the digestive tract), which increases the efficiency of digestion and resorption of nutrients (better digestibility of basic nutrients that reduces the production of ammonia and carbon dioxide), as well and resistance to disorders caused by enteropathogenic bacteria. Considering better feed utilisation, the described nutritional strategy results in higher body weight of broilers, better body gaim, and lower feed conversion.Zbornik sažetak

    Značaj sprovođenja biosigurnosnih mera u cilju sprečavanja naseljavanja golubova u urbanim i ruralnim sredinama

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    Divlji golubovi (Columba livia) predstavljaju sinantropne vrste kako urbanih tako i ruralnih područja. Njihova izuzetna sposobnost adaptacije doprinela je povećanju brojnosti ove populacije, posebno u gradskim sredinama. Prisustvo ovih vrsta ptica dovodi do mnogobrojnih negativnih posledica, uključujući ekonomske štete i ekološke uticaje kao i epidemiološko-epizootiološke rizike, predstavljajući potencijalne rezervoare i prenosioce različitih patogena koji mogu ugroziti zdravlje ljudi i životinja. Za efikasnu kontrolu populacije neophodan je integrisani pristup upravljanja štetočinama (IPM), sa ciljem dugoročnog smanjenja brojnosti, uz pažljivo razmatranje ekoloških i socijalnih aspekata. Primenom kako standardnih, tako i inovativnih rešenja u postupcima suzbijanja golubova, uključujući razumevanje njihovog ponašanja, ishranu i navike gneždenja, može se uspešno izvršiti regulacija brojnosti ove populacije.Zbornik radov

    Disorder of water and electrolyte balance in cattle

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    Ruminants’ water needs depend on several factors. Water and electrolyte imbalances can disrupt production and, reproductive performance as well as overall health. Fluid replacement is a key step in the treatment of diseases such as calf diarrhea. This review work aimed to describe in more detail and indicate the importance of water and electrolyte imbalance disorders in cattle, especially calves, as the most sensitive category of cattle

    Fulfilling the requirements for exporting fish meat products (tuna pâté) to the United States market

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    The objective of this work was to ensure all necessary prerequisites for exporting canned fish meat (tuna pâté) to the United States market are met. To accomplish this, thermocouple measurements were conducted during sterilization in the autoclave to validate the heat treatment process. Initially, a temperature distribution study was carried out during regular production, followed by a heat penetration study. In both cases, the success criteria were satisfied. The temperature distribution was monitored using nine thermocouple probes, and within one minute after the holding time (come up time), the temperature at all measured points in the autoclave medium exceeded 120°C. For the heat penetration study, eleven probes were used, eight placed in the thermal centre of the cans and three in the autoclave medium. All probes located at the thermal centre achieved F0 values ranging from 6.88 to 8.56 minutes, confirming the safety and effectiveness of the sterilization process for tuna pâté intended for export to the United States

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