Acta Orientalia Vilnensia
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Service Provisioning in Digital Twin Networks with Semantic-Aware Information Centric Networking
No full textIl ricorso per motivi di competenza
No full textIl contributo analizza il ricorso ordinario in Cassazione per motivi di competenza (art. 360, c. 1, n. 2) soffermandosi sui più recenti orientamenti giurisprudenziali e sulle principali questioni interpretative connesse all'istituto
Fish Welfare in Recirculating Aquaculture Systems (RAS): The Imperative for Environmental Enrichment (EE)
No full textAquaculture has become the fastest-growing food production sector worldwide, recently
surpassing wild-capture fisheries in total output. This rapid expansion underscores the
need to ensure sustainability through robust animal welfare standards. Recirculating Aquaculture
Systems (RAS) are increasingly adopted due to their advantages in biosecurity,
water efficiency, and production control. However, these systems often expose fish to
highly artificial and environmentally impoverished conditions, which may negatively
affect their welfare. This article examines fish welfare in RAS through the lens of environmental
enrichment (EE), arguing that its implementation is essential to address behavioral,
cognitive, and physiological needs. By integrating EE into RAS design and management,
it is possible to move beyond traditional homeostatic welfare models focused solely on
stress reduction toward an allostatic framework that emphasizes adaptability, agency, and
positive experiences. Such an approach supports the concept of providing farmed fish
with a “life worth living.” The paper highlights the ethical and practical implications of
enrichment strategies and emphasizes their potential role in promoting sustainable and
welfare-oriented aquaculture practices
Voltaire, L'Ingenuo, a cura di Pierino Gallo
No full textUn giovane urone – membro di una tribù indigena del Canada – giunge, in una calda serata estiva, sulle coste della Bretagna. Lì scopre le sue origini francesi, si converte al cristianesimo, si battezza, si innamora, conosce le asprezze della prigione e la corruzione dei potenti, si istruisce in compagnia di un giansenista e riacquista la libertà grazie ai “servigi” di una giovane provinciale. Il percorso di crescita intrapreso permette al personaggio non soltanto di ingentilire i suoi costumi attraverso l’esperienza e l’uso della ragione, ma altresì di elaborare una critica all’intolleranza e alle ingiustizie, evidenziando i lati più oscuri della Francia del Re Sole.
Gioiello narrativo del Secolo dei Lumi, ironico e profondo, L’Ingenuo (1767) fa riecheggiare ancora oggi il suo messaggio universale: soltanto chi accoglie in sé il cambiamento e si accosta con sguardo attento al prossimo può aspirare a comprendere le verità del mondo e ad alleviare, praticando la paziente saggezza del filosofo, i dolori della vita
Mapping Memory and Legitimating Heritage: The Case of Two Italian Parks
No full textBuilding upon in-depth interviews, surveys, participant observation and an extensive body of documentary material gathered in the last ten years, this chapter will shed light upon the variables that can influence heritage construction processes and the way conflicts over memory can evolve when that memory is used to condition political choices on the present. The authors submit that the urban fabric has always been characterized by a duality between past and present, but it is only when this becomes a recognized heritage, for example, a UNESCO World Heritage Site, that the urban fabric is enhanced as such, i.e., becoming a historic centre. The chapter will rely upon a comparative theoretical framework and focus on two Italian Parks: The Archaeological Park of Tindari (Sicily) and the National Park of the Colline Metallifere (Tuscany). The two authors of the chapter are deeply involved in the life of the two Parks for sharing or having shared professional or institutional positions related to them
Le voci e le storie. Saperi, progetti e compiti dei cantastorie del Sud dai “veri” agli “ultimi”.
No full textA Two-Year Pharmacovigilance Analysis of Adverse Drug Reactions Reported from a University Allergy Setting
No full textBackground: Adverse Drug Reactions (ADRs) are a significant public concern because of their impact on healthcare systems. Spontaneous reporting of ADRs is crucial for monitoring drug safety and recognizing possible risk factors. The objective of this study was to characterize ADR reports from the Allergy and Clinical Immunology Unit of the G. Martino University Hospital, Messina, Italy. Methods: A retrospective analysis was conducted, including all ADRs spontaneously reported from patients attending the clinic because of at least one previous ADR, from June 2022 to June 2024. Results: A total of 388 reports were collected, mainly from females (71.1%) and adult patients (84.3%). ADRs were mostly immediate, from antibiotics and anti-inflammatory drugs (61.5%), with a high prevalence of cutaneous and respiratory disorders. Delayed reactions were mostly from endocrine therapies, vaccines, and antiepileptics. Anaphylactic shock was present only in 13 ADR reports (3.35%). A higher risk of developing serious ADRs was found in elderly patients aged ≥65 years (p = 0.012). An original finding was that a positive history of allergies (p = 0.023) and past medical history of ADRs (p = 0.045) were negatively correlated to the occurrence of a serious ADR, probably because patients had been previously followed in an allergy setting and alerted about ADRs. Conclusions: This study underlines the role of ADR follow-up in allergy settings to identify preventable traits and related risk factors; appropriate ADR reporting and collaboration between allergists and pharmacovigilance centers can be a winning strategy for ADR prevention
When Volatility Turns, Recessions Follow
No full textDo shifts into high stock-market volatility foreshadow recessions rather than merely accompany them? Prior work shows volatility rises in downturns and can help shorthorizon forecasts, but the timing of discrete volatility regime changes relative to business-cycle turning points is less understood. Using quarterly data for the United States, United Kingdom, Japan, Germany, Italy, and France (1960–2019; country-specific start dates), we estimate a bivariate Markov-switching model that jointly classifies high/low output growth and high/low return volatility, and tests restrictions on the transition structure. In the United States, United Kingdom, Japan, and France, entry into the high-volatility state typically precedes recession onset by one to two quarters. For Germany and Italy, the output and volatility state processes are approximately independent. These results suggest that volatility-regime switches are a medium horizon early-warning signal, consistent with uncertainty and risk-premium repricing that tighten funding conditions in more market-based financial systems
Design and experimental characterization of a water-driven volumetric foam proportioning system for firefighting applications
No full textIn the firefighting field many fire protection systems, involve the mixing of extinguishing foam concentrate with water at prescribed mixing ratios in order to enhance the extinguishing performances of water alone. A wide variety of foam concentrates is available on the market and new formulations, such as fluorine-free foam concentrate (FFF), are being developed in response to environmental concerns. Some of these concentrates exhibit high, often non-Newtonian viscosity, which has forced manufacturers to adapt proportioning systems to a broad range of fluid properties. Since foam properties have a strong impact on proportioning performance, inappropriate mixing may lead to inaccurate ratios and degraded extinguishing capability.
The present work aims to deepen the understanding and support the design of a foam-concentrate proportioning system for firefighting applications, capable of operating reliably across a wide range of foam-concentrate properties. The focus is placed on water-driven volumetric proportioning, a solution that offers robustness, independence from external power sources and predictable dosing behaviour
YY1 in four dimensions: From context-dependent transcription factor to spatiotemporal gene regulator
No full textYY1 is a multifunctional transcription factor whose regulation spans transcriptional, post-transcriptional, and post-translational layers, conferring remarkable context-dependent plasticity. Several studies carried out in YY1-deficient mouse models highlight its essential roles in embryogenesis, organogenesis, and cellular homeostasis, while its deregulation in adulthood predisposes to multiple chronic diseases. In cancer, YY1 displays a bidirectional function, acting as either oncogene or tumor suppressor depending on cellular context and tumor type, and reshaping transcriptional and epigenetic networks. Emerging evidence further identifies YY1 as a clock-controlled gene and architectural regulator of circadian transcription, bridging together enhancer-promoter communication, chromatin state, and the temporal dimension of gene expression. In this context, its deregulation links circadian misalignment with oncogenic signaling, underscoring its key role as a diagnostic and prognostic biomarker, as well as a therapeutic target, thus highlighting its relevance in precision oncology