Hal-Diderot
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Ordonnancement dynamique d'un système de fabrication flexible piloté par des jumeaux numériques
International audienc
Depressed myocardial cross-bridge cycling kinetics in a female guinea pig model of diastolic heart failure
International audienceCardiac hypertrophy is associated with diastolic heart failure (DHF), a syndrome in which systolic function is preserved but cardiac filling dynamics are depressed. The molecular mechanisms underlying DHF and the potential role of altered cross-bridge cycling are poorly understood. Accordingly, chronic pressure overload was induced by surgically banding the thoracic ascending aorta (AOB) in ∼400 g female Dunkin Hartley guinea pigs (AOB); Sham-operated age-matched animals served as controls. Guinea pigs were chosen to avoid the confounding impacts of altered myosin heavy chain (MHC) isoform expression seen in other small rodent models. In vivo cardiac function was assessed by echocardiography; cardiac hypertrophy was confirmed by morphometric analysis. AOB resulted in left ventricle (LV) hypertrophy and compromised diastolic function with normal systolic function. Biochemical analysis revealed exclusive expression of β-MHC isoform in both sham control and AOB LVs. Myofilament function was assessed in skinned multicellular preparations, skinned single myocyte fragments, and single myofibrils prepared from frozen (liquid N2) LVs. The rates of force-dependent ATP consumption (tension-cost) and force redevelopment (Ktr), as well as myofibril relaxation time (Timelin) were significantly blunted in AOB, indicating reduced cross-bridge cycling kinetics. Maximum Ca2+ activated force development was significantly reduced in AOB myocytes, while no change in myofilament Ca2+ sensitivity was observed. Our results indicate blunted cross-bridge cycle in a β-MHC small animal DHF model. Reduced cross-bridge cycling kinetics may contribute, at least in part, to the development of DHF in larger mammals, including humans
The use of Machine Learning for predicting the sentence given by the population at a crime scene
International audienceViolence and authoritarianism are present factors in most societies, as well as prejudice and discrimination. Social variables, such as race, profession, and place of residence, are important factors that interfere with the portrait of each member of society and may override the truth and how judicial laws are applied to them. The main goal of this work is to apply machine learning techniques to predict the verdict given by the population to the accused at a crime scene. The database was created with the social information collected from 1102 participants from 21 different states of Brazil, in the year 2020. The data used are part of the “Brasil 2020 Decide” survey, which has assertions about social conditions and authoritarian behavior related to economic conditions, color and race. In the described crime scenario, the SVM (Support Vector Machine) algorithms achieved an average accuracy of 68% in predicting the sentence for the accused
Computing Vegetation Indices from the Satellite Images Using GRASS GIS Scripts for Monitoring Mangrove Forests in the Coastal Landscapes of Niger Delta, Nigeria
International audienceThis paper addresses the issue of the satellite image processing using GRASS GIS in the mangrove forests of the Niger River Delta, southern Nigeria. The estuary of the Niger River Delta in the Gulf of Guinea is an essential hotspot of biodiversity on the western coast of Africa. At the same time, climate issues and anthropogenic factors affect vulnerable coastal ecosystems and result in the rapid decline of mangrove habitats. This motivates monitoring of the vegetation patterns using advanced cartographic methods and data analysis. As a response to this need, this study aimed to calculate and map several vegetation indices (VI) using scripts as advanced programming methods integrated in geospatial studies. The data include four Landsat 8-9 OLI/TIRS images covering the western segment of the Niger River Delta in the Bight of Benin for 2013, 2015, 2021, and 2022. The techniques included the 'i.vi', 'i.landsat.toar' and other modules of the GRASS GIS. Based on the GRASS GIS 'i.vi' module, ten VI were computed and mapped for the western segment of the Niger River Delta estuary: Atmospherically Resistant Vegetation Index (ARVI), Green Atmospherically Resistant Vegetation Index (GARI), Green Vegetation Index (GVI), Difference Vegetation Index (DVI), Perpendicular Vegetation Index (PVI), Global Environmental Monitoring Index (GEMI), Normalized Difference Water Index (NDWI), Second Modified Soil Adjusted Vegetation Index (MSAVI2), Infrared Percentage Vegetation Index (IPVI), and Enhanced Vegetation Index (EVI). The results showed variations in the vegetation patterns in mangrove habitats situated in the Niger River Delta over the last decade as well as the increase in urban areas (Onitsha, Sapele, Warri and Benin City) and settlements in the Delta State due to urbanization. The advanced techniques of the GRASS GIS of satellite image processing and analysis enabled us to identify and visualize changes in vegetation patterns. The technical excellence of the GRASS GIS in image processing and analysis was demonstrated in the scripts used in this study
Two-fluids plane or axisymmetric Poiseuille flow at optimum: A (quasi)analytical study
The solution of the two-fluids plane or axisymetric Poiseuille flow is derived analytically. Then, the conditions for the maximum flow rate of the most viscous fluid are analyzed in terms of fluids volume fractions. The axisymmetric case is totally analytical, whereas the plane one is not. In the axisymmetric case, it is shown that an optimum can be found only if the most viscous fluid (the liquid) is inside and the less viscous one (the gas) is outside. In the plane case, the maximum flow rate of the "liquid" can reach 4 times that of the classical Poiseuille flow in the limit of vanishing viscosity of the "gas"
Measuring the Effect of Organizational Climate on the Employees' Work Performance as perceived by the Employees
International audienceResearch in organizational climate paves the way to understanding the work environment. The study explored the effect of organizational climate on the individual work performance of the employees. To deepen the understanding of the concepts of the study, the literature was reviewed. The study used descriptive assessment and correlational research design and used descriptive and inferential statistics to analyze the data. The population included all employees of the Divine Word College of Laoag, hence total enumeration was applied. The study found that all dimensions of organizational climate were high, but not very high, likewise with individual work performance. Analysis of Variance showed a significant correlation between organizational climate and individual work performance
Illégalité d'une prise en compte forfaitaire des durées de déplacements inter-vacations pour l'évaluation du temps effectif de travail
International audienc
Chemical Leslie effect in a chiral smectic- C* film: Nonsingular target patterns
International audienceWe analyze experimentally and theoretically the winding and the unwinding of the c-director in a chiral smectic C film crossed by an ethanol flow. This leads to a target pattern under crossed polarizers when the +1 defect imposed by the boundary conditions is pinned on the edge of the film. We show that the target is deformed at the center of the film when it is subjected to a flow of ethanol because of the presence of two recirculation vortices of chemohydrodynamical origin. This deformation and the two vortices disappear during the unwinding of the target when the ethanol flow is stopped. This unambiguously shows that the target deformation is due to the vortices and not to the elastic anisotropy. These two points are confirmed theoretically. An estimate of the two so-called chemomechanical and chemohydrodynamical Leslie coefficients is also derived from this study
Le nouveau statut de l'entrepreneur individuel
International audienceLa loi n° 2022-172 du 14 février 2022 institue un nouveau statut de l'entrepreneur individuel. Cette loi prévoit notamment qu'il dispose de deux patrimoines, un professionnel et un personnel, de plein droit