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Pushing AFM Boundaries with Optomechanics: From Ultra-High-Speed to Quantum Sensing
International audienceOver the past 15 years, advances in optomechanics and micro-/nano-fabrication have enabled the development of miniature devices that combine optical cavities with high-quality mechanical resonators. In these systems, strong optomechanical coupling allows for the detection of sub-femtometer displacements at ultra-high frequencies, opening up new technological avenues and experimental windows in Atomic Force Microscopy. This progress paves the way for faster AFM probes with broader bandwidths, enabling ultra-high-speed imaging and nanosecond-scale force spectroscopy to probe molecular biophysics, for example. These advancements also lay the foundation for future quantum AFM and measurements down to the single-phonon level
Comparative analysis of ray tracing and Rayleigh fading models for distributed MIMO systems in industrial environments
International audienceThis paper presents a detailed analysis of coverage in a factory environment using realistic 3D map data to evaluate the benefits of Distributed MIMO (D-MIMO) over colocalized approach. Our study emphasizes the importance of network densification in enhancing D-MIMO performance, ensuring that User Equipment (UE) remains within range of multiple Access Points (APs). To assess MIMO capacity, we compare two propagation channel models: ray tracing and stochastic. While ray tracing provides accurate predictions by considering environmental details and consistent correlations within the MIMO response, stochastic models offer a more generalized and efficient approach. The analysis outlines the strengths and limitations of each model when applied to the simulation of the downlink (DL) and uplink (UL) single-user capacity in various D-MIMO deployment scenarios
SCIENTIFIC ADVICE on the safety of Diethylamino Hydroxybenzoyl Hexyl Benzoate – DHHB – S83 - SCCS/1678/25 – Final Version
International audienceSCIENTIFIC ADVICE on the safety of Diethylamino Hydroxybenzoyl Hexyl Benzoate – DHHB – S83 - SCCS/1678/25 – Final VersionU. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads, J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. Wijnhoven, E. Benfentati, N. Cabaton, E. Corsini, Ch. Delmaar, A. Koutsodimou, H. Louro, W. Uter, N. von GoetzThe SCCS adopted this Opinion during the plenary meeting on 26 June 2025 (25 Pages)Mise en ligne : 30 June 2025https://health.ec.europa.eu/publications/sccs-scientific-advice-safety-diethylamino-hydroxybenzoyl-hexyl-benzoate-dhhb-s83_enhttps://health.ec.europa.eu/document/download/0bb2a0be-ba7c-4a1f-96df-d57d18c1316f_en?filename=sccs_o_299.pdfDetailsPublication date30 June 2025AuthorScientific Committee on Consumer Safety (SCCS)DescriptionSCCS members: U. Bernauer, L. Bodin, Q. Chaudhry, P.J. Coenraads (Chairperson and Rapporteur), J. Ezendam, E. Gaffet, C. L. Galli, E. Panteri, V. Rogiers, Ch. Rousselle, M. Stepnik, T. Vanhaecke, S. WijnhovenSCCS external experts: E. Benfentati, N. Cabaton, E. Corsini, Ch. Delmaar, A. Koutsodimou, H. Louro , W. Uter, N. von GoetzContact: [email protected] request from: European CommissionSCCS Number: SCCS/1678/25Adopted on: 26 June 2025Conclusion of the opinion:(1) Considering the recent concerns over the presence of DnHexP as a contaminant in the production of Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) used as a UV-filter in cosmetic products, as well as in view of technical and scientific progress and taking under consideration in particular the various health concerns, the SCCS is requested to identify the maximum safe level of DnHexP as a contaminant in DHHB preparationsConsidering the health concerns associated with DnHexP, the SCCS calculated a maximum safe level of 0.026% (260 ppm) for this impurity in the UV filter DHHB. This applies when DHHB is used up to 10% in cosmetic products and only if DnHexP is an unavoidable impurity.2) Does the SCCS have any further scientific concerns regarding the presence of DnHexP in DHHB as a UV-filter in cosmetic products?The SCCS has noted from the available information that DnHexP was below the level of detection in several DHHB containing sunscreen products and other DHHB sources, provided that a specific manufacturing process is applied. The information also showed that it is technically possible to lower the levels of DnHexP in DHHB down to 1 ppm. Considering the existence of such alternative manufacturing process for DHHB, the SCCS is of the opinion that a trace level of 1 ppm should be the target for the maximal level of DnHexP as an impurity in DHHB.Keywords:SCCS, scientific advice, Diethylamino Hydroxybenzoyl Hexyl Benzoate, DHHB, S83, Regulation 1223/2009, CAS/EC No. 302776-68-7/443-860-6Opinion to be cited as:SCCS (Scientific Committee on Consumer Safety), scientific advice on the safety of Diethylamino Hydroxybenzoyl Hexyl Benzoate – DHHB -S83 (CAS/EC No. 302776-68-7/443-860-6) from cosmetic products, preliminary version of 14 February 2025, final version of 26 June 2025, SCCS/1678/25
Télétravail dégradé : quels risques identifier afin de mieux les anticiper ? Une approche empirique qualitative exploratoire au sein d’une compagnie d’assurance-vie
International audienceImposé en 2020, le télétravail s’installe durablement en mode hybride. Recommandé par le ministère du Travail puis obligatoire dès le 3 janvier 2022, il s’exerce alors à nouveau dans un cadre contraignant. L’obligation prend fin le 2 février 2022 . Le travail exercé à domicile a bouleversé l’organisation intra-familiale, contribué à un accroissement de la charge de travail et à des situations de stress ou d’isolement. Le télétravail à domicile s’est exercé dans des conditions inégales en fonction du lieu de vie et de la position sociale du ménage, ainsi que du sexe (Étude COCONEL, 2020 ; Boston Consulting Group, 2021). Notre démarche s’inscrit dans ce questionnement et vise à démontrer l’impact éventuel de la formalisation du travail à domicile sur les inégalités de genre et l’influence sur la rémunération. La partie empirique repose suL’Accord National Interprofessionnel relatif à la mise en œuvre du télétravail de 2020, précise les contours de la relation managériale en télétravail et notamment l’importance de l’évaluation des risques professionnels. Il semble légitime de s’interroger sur l’émergence et l’évolution de tels risques apparus en situation de télétravail contraint, dégradé. Ce télétravail subi a-t-il permis de révéler de nouveaux risques ? Cette recherche propose une analyse des risques psychosociaux, de l’émergence du harcèlement managérial, de l’hyper-connectivité, des accidents du travail à domicile, des risques relatifs à la sauvegarde et la protection des données et de la fraude interne, en situation de télétravail à domicile contraint.Nous mobilisons la littérature relative aux risques et particulièrement en situation de télétravail et convoquons la jurisprudence relative.La partie empirique repose sur une étude exploratoire, qualitative, conduite entre mi-février 2020 et mi-février 2021, auprès de 43 cadres d’une compagnie d’assurance-vie confrontée au télétravail contraint depuis mars 2020.L’argument principal de cette contribution est que le télétravail subi, dégradé a révélé des risques majeurs qu’il faut désormais être en mesure d’anticiper afin d’éviter une dégradation des conditions de travail et prévenir les contentieux prud’homaux.r une étude quantitative menée en 2022 auprès de 211 répondants travaillant à domicile. Nous mobilisons la littérature sur le télétravail, les inégalités, la théorie des conventions et les théories contractualistes. Les résultats révèlent que la formalisation du travail à domicile n’influence pas la rémunération, les facteurs de contingence (formalisation induite) en revanche produisent des inégalités de genre en matière de rémunération. L’absence d’espace de travail dédié à domicile engendre des inégalités de rémunération
Detailed Design Optimization of Reinforced Concrete Flexural Sections Using MultiObjective Genetic Algorithm
International audienceReinforcement layout design is essential in reinforced concrete (RC) structures. Traditional meth-ods rely on standard-based calculations for mechanical strength and durability but fail to balance objectives like cost and carbon footprint. In this study, the problem is formulated as a constrained multi-objective optimization, integrating design code calculations with a genetic algorithm (GA) to efficiently find optimal designs. Application to the design of a flexural beam shows that the algorithm converges quickly to solutions close to those obtained through exhaustive search. It also successfully optimizes complex reinforcement layouts (with more than three different bar diameters) while maintaining high modularity and allowing constraints to limit reinforcement complexity
Early B cell maturation and immune evasion mechanisms in PRRSV-1 infection
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Contributing to the ELIXIR training life-cycle from the GTN perspective
International audienceThe Galaxy Training Network (GTN) offers a robust platform for bioinformatics training, complementing the ELIXIR Training Platform. With 34 topics, 464 tutorials, and 22 learning pathways, GTN provides comprehensive educational experiences, extending beyond Galaxy to include AI and programming languages.GTN has achieved a perfect FAIRChecker score, showcasing its commitment to FAIR principles through automated infrastructure. The platform excels in participant engagement, with 3,000+ feedback responses aggregated automatically to enhance training effectiveness. Learning pathways, curated by experts, offer coherent and progressive learning experiences suitable for self-learning or training events.Contributions to GTN are streamlined through Google Forms and automatic testing, allowing users without technical expertise to submit content, thereby increasing community participation. GTN recognizes contributors with detailed profiles and extends this recognition to projects, institutions, and funders. Community Pages provide real-time insights into growth and collaboration.Event organization is enhanced with GTN Event Pages, offering tools like course handbooks and social media promotion, supporting both in-person and virtual events integrated with TeSS. GTN’s Video Library 2.0 simplifies the submission of recordings, expanding multimedia resources.The platform’s focus on accessibility is evident from the uptake by communities such as hCNV, Single-Cell, RDM. Additionally, initiatives like the Galaxy Training Academy events attracted 10,000+ registrations and covering diverse topics. In summary, the Galaxy Training Network offers a technically advanced and user-friendly platform that complements the ELIXIR Training Platform and its Training Life Cycle. Its commitment to FAIR principles, community engagement, and innovative features makes it a valuable resource for the bioinformatics training community
A new sinter-forging process based on a 915 MHz solidstate microwave source for sintering of oxides ceramics
International audienceThis study presents the development of a fully instrumented sinter-forging process using a 915 MHz solid-state microwave source for the rapid and controlled sintering of dense oxide ceramics. Compared to conventional magnetron-based systems, the solid-state microwave source enables precise frequency tuning for optimal impedance matching and resonance conditions. Modeling and experimental characterization of the microwave applicator have enabled us to position the sample correctly in the cavity, ensuring efficient energy transfer and homogeneous heating. Sintering experiments carried out on alumina powder, both with and without applied pressure, revealed that the pressure-assisted process significantly improved densification, yielding near-complete density and increased hardness (21.6 GPa), while maintaining fine microstructures. This method highlights the potential of microwave-assisted sinter-forging for producing advanced ceramics with improved properties
Optimization of direct ink writing of Si₃N₄ suspensions for the fabrication of self-supported structure
International audienceSi₃N₄ is an advanced ceramic highly attractive for applications in aeronautics, aerospace, and other industries. Additive manufacturing (AM) is suitable for producing advanced ceramic parts with complex shapes, eliminating the need for machining to achieve the final component (near-net shape concept), thereby reducing costs. In this context, direct ink writing (DIW), which involves the extrusion of low organic aqueous suspensions, is wellsuited for the rapid printing of large shapes with varying wall thicknesses. In this work, the formulation of a Si3N4 aqueous suspension has been fully developed. The optimal adding amounts of dispersant, ceramic loading, and organic binders have been determined to achieve suitable rheological properties for DIW. The suspension rheology has been adjusted to produce tall, self-supported, thinner parts, such as radomes, which are particularly challenging due to their sensitivity to slumping. These parts were sintered at 1850°C in N2 atmosphere and exhibit a distinctive microstructure with typical non-equiaxed Si₃N₄ needle-like grains. The microhardness value of 1505 HV and the flexural strength of 374 MPa were comparable to Si₃N₄ ceramics fabricated through conventional processing