4926 research outputs found
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Pregnancy-acquired memory CD4+ regulatory T cells in human PBMCs
No full textData set of FCS files from human PBMC samples (please see xlsx file for detailed sample description). They represent the raw data files for flow cytometry data published in Figure 1 of the publication "Pregnancy-acquired memory CD4+ regulatory T cells improve pregnancy outcome in mice" by Thiele, K. et. al. published in Nature Communication (DOI: 10.1038/s41467-025-61572-w).
Abstract of the publication:
Subsequent pregnancies are generally less prone to obstetric complications. A successful pregnancy outcome requires pivotal immunological adaptation to ensure immune tolerance towards the fetus. Thus, the lower risk for pregnancy complication during subsequent pregnancies may be attributable to immune memory mounted during first pregnancies. Here we identify higher frequencies of fetal-antigen-specific CD4+ regulatory T (Treg) cells both postpartum and in subsequent pregnancies in mice which are partly originating from trans-differentiated Th17 cells. Our functional experiments demonstrate that these CD4+ Treg cells have memory functions (CD4+ mTreg) and account for an improved fetal development and pregnancy outcome, also during adverse conditions, such as gestational sound stress. Using a high-throughput single-cell quantification method, we identify candidate markers for the detection of CD4+ mTreg cells, which include CXCR4 and CD274. Our findings thus contribute to the improved understanding of pregnancy-induced immune memory and foster the identification of immune targets aiming to reduce the risk for immune-mediated pregnancy complications
White Americans' preference for Black people in advertising has increased in the past 66 years: A meta-analysis
No full textThe uploaded zip file contains all data, code and the publication (manuscript + appendix) for the paper "White Americans’ preference for Black people in advertising has increased in the past 66 years: A meta-analysis", published in PNAS on February 20, 2024
ZfKD | OMOP CDM - Metadata Cataloge
No full textData integration and interoperability are fundamental aspects of implementing the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM). In the context of oncology, various data sources, such as cancer registries and epidemiological databases, generate data. These sources often use different data formats, structures, and standards, making comparability and analysis challenging. Metadata is crucial for this process, as it acts as a contextualized interface that facilitates the integration and harmonization of these diverse data sources. By establishing clear metadata standards, OMOP CDM ensures consistency in key attributes such as data types, reference formats, and data descriptions, which makes integration smoother and more effective. This standardization helps maintain data consistency and minimizes errors or misunderstandings that can arise from inconsistent data
ZfKD | OMOP CDM - Metadata Cataloge
No full textData integration and interoperability are fundamental aspects of implementing the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM). In the context of oncology, various data sources, such as cancer registries and epidemiological databases, generate data. These sources often use different data formats, structures, and standards, making comparability and analysis challenging. Metadata is crucial for this process, as it acts as a contextualized interface that facilitates the integration and harmonization of these diverse data sources. By establishing clear metadata standards, OMOP CDM ensures consistency in key attributes such as data types, reference formats, and data descriptions, which makes integration smoother and more effective. This standardization helps maintain data consistency and minimizes errors or misunderstandings that can arise from inconsistent data
The PHOENIX/1D NewEra model atmosphere grid: Access software & low resolution synthetic spectra
No full textSoftware to access NewEra spectrum files (DOI 10.25592/uhhfdm.16727) from python and an example reader.
get_NewEra_from_FDR.py get a single model from the data repository.
example_read_HSR_H5.py reads data from a single model h5 file.
example_read_structure_from_HSR_H5.py reads and parses model structure data (radii, temperatures etc.)
example_read_gaia_fmt.py read the first spectrum of one of the GAIA format archives
list_of_available_NewEraV2_models.txt: Version 2.0 of the NewEra spectra (for Teff>=5000K). Use these files!
list_of_available_NewEra_models.txt is a list of all available models, MD checksums, file sizes and download links.
Readme.PHOENIX.gaia_fmt.txt explains the format of the GAIA archive files
PHOENIX-NewEraV2-GAIA-DR4_v3.4-PHOTOMETRY.tar.gz archive with Version 2 of the GAIA DR4 photometry
PHOENIX-NewEraV2-GAIA-DR4_v3.4-SPECTRA.tar.gz archive with Version 2 of the GAIA DR4 spectra
PHOENIX-NewEraV2-LowRes-SPECTRA.tar.gz archive with Version 2 of all low resolution spectra
PHOENIX-NewEraV2-JWST-SPECTRA.tar.gz archive with Version 2 of all spectra in the JWST spectral range and resolution
PHOENIX-NewEra-LowRes-SPECTRA.tar.gz archive with all low resolution spectra
PHOENIX-NewEra-JWST-SPECTRA.tar.gz archive with all spectra in the JWST spectral range and resolution
NewEra_for_GAIA_DR4.tar Synthetic spectra, colors and BCs in GAIA DR4 format as tar file, includes Readme
Development and Evaluation of a Collaborative Touch Table Port Planning Support System
No full textThis work presents the development and evaluation of a touch table tool as a port planning system. Port planning is a complex, interdisciplinary process carried out to design and agree on the use and structure of port areas. Since people from different fields are involved, successful collaboration is crucial. Previous research has shown that touch tables can improve collaboration between co-located users. In a focus group evaluation with potential end users, we explored the potential and challenges of using a touch table for port planning. The results show that such a system should be carefully designed and must cover complex planning processes. Overall, however, the participants see potential in using a touch table as a planning hub to facilitate discussion and collaboration
DGS-Korpus SessionDirector elicitation materials
No full textElicitation materials for DGS-Korpus data collections. All materials are contained in a Keynote presentation file, used as part of SessionDirector during recording sessions. Backwards compatible with all previous recording sessions
Molecular Cross-linking of MXenes: Tunable Interfaces and Chemiresistive Sensing
No full textTheoretical raw data for the publication:
Yudhajit Bhattacharjee, Lukas Mielke, Mahmoud Al-Hussein, Shivam Singh, Karen Schaefer, Borja Rodriguez-Barea, Qiong Li, Anik Kumar Ghosh, Artur Erbe, Carmen Herrmann, Yana Vaynzof, Andreas Fery, Hendrik Schlicke, Molecular Cross-linking of MXenes: Tunable Interfaces and Chemiresistive Sensing
This includes Density Functional Theory (DFT) calculations of the adsorption energies of butylamine ligands on Ti₃C₂Tₓ surfaces, as well as structural optimizations of diamine cross-linked MXene surfaces to identify the lowest-energy configurations and corresponding center-to-center distances.
A preprint can be found at arXiv:2504.11166 (https://doi.org/10.48550/arXiv.2504.1116)
Supporting Information for the ActivityFinder publication
No full textThree supporting data files for the Activityfinder publication are given here.
Two are redundantly saved and also present in the journal article: the unwanted ligand list and the amino acid mapping used for the Activityfinder.
Additionally, a database dump of the complete ActivityDB used for the publication is provided
Intermediate progress reports on BOLD social action projects: a cross-case analysis
No full textThis document provides a consolidated analysis of the intermediate progress reports produced by student teams implementing BOLD social action projects across six partner institutions. It outlines the structure of the reporting template and synthesises insights from 34 completed submissions, highlighting how the projects evolved over time in diverse educational and sociolinguistic settings. The report examines contextual information, pedagogical approaches, collaborative dynamics, and students’ reflections on progress, challenges, and early impact. The findings illustrate how student teachers engaged with linguistic and cultural diversity, strengthened community partnerships, and developed more reflective, inclusive, and socially responsive professional practices