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Experiences of Academicians at a Faculty of Health Sciences Regarding Students of Generation Z: A Phenomenological Research
No full textInvestigation of in vitro Cytotoxic Activity of Arbutin on Human Ovarian Cancer Cell Line Arbutinin İnsan Yumurtalık Kanseri Hücre Hattında in vitro Sitotoksik Aktivitesinin Araştırılması
No full textArbutin is one of the chemical compounds commonly found in cosmetics. Arbutin's potential effects on ovarian cancer were investigated in this study using the human serous cystadenoma cancer cell line (SKOV3). Cytotoxicity levels and IC50 values of arbutin were determined using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) method. Depending on the increase in the applied doses, arbutin was found to have toxic activity on cancer cells. As a result of the immunocytochemical analysis performed on the cells applied with the IC50 value, it was found that arbutin at the IC50 dose increased Caspase 3 immunoreactivity in SKOV3 cells compared to the control group. Considering that arbutin increased apoptotic Caspase 3 activation in SKOV3 cells at the IC50 dose, elucidation of the molecular mechanisms behind these effects of arbutin may contribute to the development of a new perspective in treatment
Hemşirelik Öğrencilerinin Kişisel Sağlık Verilerinin Kayıt ve Korunması Konusundaki Tutumları ve Etkileyen Faktörler
No full textThe plant-based photodiode with Stachys lavandulifolia interfacial layer
No full textIn this study, we used an extraction obtained naturally from Stachys lavandulifolia Vahl. (StLa) to fabricate Al/StLa/p-Si plant-based (PB) photodiode. The optical, structural, and the optoelectronic properties of PB photodiode were investigated. The band gap (Eg) of StLa was determined to be 3.2 eV from UV–vis measurements. The arithmetic means of the surface height deviations of StLa were found to be about 0.20–0.30 nm by AFM. The J-V characteristics of the fabricated photodiode were investigated in the dark and under different illumination intensities in the range of 30–100 mW.cm−2. The ideality factor (n), saturation current (I0), barrier height (ΦB0) and rectification rate (RR) of the fabricated PB photodiode in dark were found to be 1.43, 1.52 × 10−10 A, 0.829 eV and 2.5 × 105, respectively. In addition, the spectral sensitivity (SR), detectivity (D*), noise equivalent power (NEP) and the spectral external quantum efficiency (EQE) of the fabricated PB photodiode under UV-A lamp with 350 nm wavelength were found to be 0.109 A/W, 9.39 × 1011 Jones, 0.943x10−13 W.Hz−1/2 and 0.37, respectively. The capacitance (C)-voltage (V) and conductance (G/ω)-voltage (V) measurements of the PB photodiode were carried out in the range of 5 kHz to 5000 kHz from −2–3 V. All these results show that the PB photodiode has a high potential for use in electronic and optoelectronic applications
Sıçanlarda Valproik Asit ile oluşturulan Otizm Spektrum Bozukluğu Modelinde GLP-1 agonisti Semaglutidin Etkisi
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Effects of group-based virtual reality training on activities of daily living and functional outcomes in older adults: a randomised control trial
No full textVirtual reality training (VRT), a fun, inexpensive and accessible technology, has the potential to improve activities of daily living (ADL) and functional status in older adults. The potential impact of VRT can be increased through group-based training. The aim of this study was to investigate the effect of group- based VRT on ADL and functional outcomes in older adults over 65 years of age. Forty-three older adults included in the study were randomized into three groups (group- based VRT, individual VRT and control group). VRT was performed with Xbox 360 Kinect twice a week for 8 weeks. Each session lasted 45 min. Physical activity level, satisfaction level with physical activity, mood, mobility and balance performance, functional exercise capacity and ADL were evaluated. 36 people completed the study. A significant group × time interaction was found in Timed Up and Go test (TUG) (F [2, 57] = 8.60; η2= 0.004, P= <.001) and in Single Leg Stance Test (SLST)) (F [2, 57] = 5.69; η2= 8.509 × 10−4, P= <.007). After 8 weeks group- based VRT showed better scores in overall TUG (p <.001) and SLST (p=.015), whereas individual VRT and control group did not exhibit significant changes. Our results suggested that 8 weeks group- based VRT could improve mobility and balance performance in older adults
