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The relationship between mental well-being, health perception and life satisfaction in third age tourists
No full textThis study examines the relationships among mental well-being, health perception, and life satisfaction among domestic and foreign tourists aged 65 and older visiting Antalya, Türkiye. Using a cross-sectional design, 500 participants were selected through quota sampling, ensuring equal distribution by gender (250 female, 250 male) and nationality (250 domestic, 250 foreign). Data were collected via face-to-face interviews with a structured questionnaire between 1 July and 15 September 2024. The average age of participants was X̄ ± SD = 68.52 ± 2.69 years. Significant differences in mental well-being and life satisfaction were observed across education levels and tourist types (p < 0.05), with foreign tourists reporting higher mental well-being (X̄ ± SD = 49.96 ± 7.56) and life satisfaction (X̄ ± SD = 23.52 ± 5.09) than domestic tourists. Correlation analysis indicated significant and positive associations among mental well- being, life satisfaction, and health perception. Specifically, mental well-being was moderately correlated with life satisfaction (r = 0.483, p < .001) and health perception (r = 0.561, p < .001). The strongest relationship was observed between health perception and life satisfaction (r = 0.658, p < .001). Multiple regression analysis confirmed that health perception and mental well-being were significantly associated with life satisfaction (p < .001). These findings highlight the importance of enhancing third age tourists’ well-being through targeted interventions focusing on health perception and mental well-being.</p
SS-56 Histerektomiye alternatif vajinal myomektomi; olgu sunumu
No full textGİRİŞ: Yoğun kanama ve pelvk ağrı şkayetyle dış merkezde hsterektom önerlen hasta tarafımıza başvurdu. OLGU: 45 yaş, Kadın hasta G3P2A1 (2 NSD) Şkayet: 6 aydırdevam eden anormal utern kanama+ şddetl pelvk ağrı Kronk hastalık: DM Geçrlmş cerrah: Yok PC: Dış merkezde yapılamamış tanısal materyal yok Smear: Normal, malgnte zlenmed. Vajnal muayene: spekulum muayenesnde servx multpar görünümde servkal os yaklaşık1-1,5 cm açıklık halnde zlend ostan görünen hperemk ktle zlend. Submukoz myom? Polp? Usg: Endometrum 20 mm kavte çersnde stmus düzeynden servkal osa uzanan 30*35 mm sapı 18 mm SM myom le uyumlu görünüm zlend. Adneksler doğal zlend. Laboratuvar: FSH:2 IU/L LH:2,33 IU/L E2:149 pg/ml 149 HB:10,1 g/dl Hastaya operatf hsteroskop le blg verld öncelkle mümkünse myomektom+ PC+ECC planlandı. Myom tabanından kanama olması ve durudurulamaz se TLH htmal le lgl b lg ver ld . Onamları alındı. Hastaya operatf hsteroskop önces vajnal myomektom planlandı. Servksn dlatayonu sağlamak amacıyla şlemden 2saat önce 400 mcg msoprostol uygulandı. Operasyon esnasında servkal açıklıktan tenekulum le myom yüzeynden tutulup çevrlerek myom tabanından ayrıldı. Kanama kontrolü ve örnekleme amacıyla hsteroskop uygulandı. Servkal dlatasyon nedenyle yeterl kavte dstansyonu oluşturulamadığı çn servkal sütür atılarak servkal os daraltıldı. Ardından yapılan hsteroskopde dstansyon sağlanarak kavte gözlend. Myom tabanı hsteroskopk gözlemle koterze edld. Kanama kontrolü sağlandı. Endometral örnekleme yapıldı. Komplkasyonsuz şleme son verld. SONUÇ: Anormal utern kanaması olan submukoz myomlu hastalarda mnmal nvazv yaklaşımlardan hsteroskop lk terch olarak değerlendrlmeldr. 3 cm ve üzerndek büyük myomlarda komplkasyondan kaçınmak adına brden çok seans htmal hastaya sunulmalıdır. Servkal osa uzanım gösteren kalın tabanlı myomlarda vajnal myomektom sonrası kanama korkulan komplkasyonlardandır. Bu durumda hsteroskopk koagulasyonla kanama kontrolü yapılableceğ akılda tutulmalıdır. Dstansyon zorluğunda servkal sütürasyon pratk br çözüm olablr. Anahtar Kelmeler: Vajnal myomektom, Operatf Hsteroskop, Hemostaz</p
ADLİ NUMUNELERDE MİKROBİYAL DEGREDASYONUN DNA BÜTÜNLÜĞÜ ÜZERİNDEKİ ETKİLERİ: ENZİMATİK YIKIM, DNaz AKTİVİTESİ ve PCR BAŞARISIZLIĞI
No full textANTIPROLIFERATIVE AND ANTIMIGRATORY EFFECTS OF HYPOGYMNIA TUBULOSA EXTRACT ON SH-SY5Y NEUROBLASTOMA CELLS
No full textGlobal variation in patient factors, interventions, and postoperative outcomes for those undergoing trauma laparotomy: an international, prospective, observational cohort study
No full textBACKGROUND: The trauma laparotomy is a definitive intervention for life-threatening abdominal injuries and a cornerstone of trauma care globally. The ability to perform an emergency laparotomy is a recognised marker of safe and effective surgical care within a health system. However, the global variation in the provision, context, and outcomes of the trauma laparotomy is unknown. This study aimed to identify the variation in patient factors, interventions, and postoperative outcomes of those undergoing a trauma laparotomy worldwide. METHODS: We conducted a prospective international observational study in 187 hospitals across 51 countries between April 1 and Dec 31, 2024. Patients who presented with a blunt or penetrating traumatic injury and underwent a laparotomy within 5 days of presentation were eligible, with information on presentation, interventions, and outcomes collected. Countries were stratified by Human Development Index (HDI) tertile and the primary outcome measure was postoperative in-hospital mortality, measured to 30 days. Adjusted mortality risk was calculated using logistic regression analysis. The study was registered to ClinicalTrials.gov (NCT06180668). FINDINGS: We included 1769 patients, comprising 563 patients (31·8%) from the lower HDI tertile, 714 patients (40·4%) from the middle HDI tertile, and 492 patients (27·8%) from the upper HDI tertile. Median age was 30 years (IQR 23-43) and 1512 patients (85·5%) were male. Patients from upper-HDI countries had a higher Injury Severity Score compared with those in middle-HDI or lower-HDI countries (median 16 [IQR 9-27] vs 9 [8-22] and 9 [4-16], respectively; p<0·0001). Crude mortality was similar across HDI tertiles, with 195 patients (11·0%) overall dying in hospital within 30 days of surgery. After adjustment, we observed higher mortality risk in the lower HDI tertile (odds ratio [OR] 3·57, 95% CI 1·78-7·28, p<0·001) and middle HDI tertile (OR 1·89, 1·06-3·43, p=0·033), compared with the upper HDI tertile. INTERPRETATION: Patients undergoing a trauma laparotomy in lower-HDI settings were less severely injured and had a higher risk of postoperative death compared with those in higher-HDI settings. There remains an opportunity to improve trauma care globally and expanding access must be matched by the development of quality services. FUNDING: Royal College of Surgeons Ratanji Dalal Research Fellowship and Engineering and Physical Sciences Research Council
