Kütahya Health Sciences University Research Information System
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Effect of endodontic case difficulty on endodontic mishaps and the number of treatment visits: a clinical study
No full textBackground: Root canal treatment, despite its high success rate, remains a challenging procedure due to anatomical complexities or procedural limitations, which may occasionally result in treatment failure. This study evaluated the influence of endodontic case difficulty, categorized by the American Association of Endodontists assessment form (low, moderate, high), on the incidence of endodontic mishaps and treatment visit requirements in postgraduate dental students. Methods: This prospective clinical study analyzed 200 root canal treatments performed on 200 patients by a postgraduate dental student, classified according to the American Association of Endodontists Case Difficulty Assessment Form. Mishaps included over-instrumentation, working length loss, underfilling, overfilling, apical transportation, instrument fracture, and perforation. Statistical analyses, including independent t-test, one-way ANOVA, Spearman’s correlation, and Chi-square tests (p 0.050). Case difficulty showed significant positive correlations with both the number of mishaps (r = 0.344, p < 0.050) and the number of treatment visits (r = 0.433, p < 0.050). Conclusion: This prospective clinical study demonstrated that the majority of procedural mishaps occurred in molar teeth and in high-difficulty cases. The American Association of Endodontists Case Difficulty Assessment Form proved useful in anticipating potential risks. Incorporating such structured case assessment tools may help clinicians reduce mishaps and enhance the success of root canal treatments. Trial registration: The study protocol was registered in the ClinicalTrials.gov database with the identifier number NCT06640790 on 11 October 2024
The impact of symptoms, proprioception, and electrodiagnostic findings on activity and participation in idiopathic carpal tunnel syndrome: an ICF framework approach
No full textBackground: The role of carpal tunnel syndrome (CTS) in activity and participation is critical for improving rehabilitation outcomes, but there is a gap in the literature on this subject. This study presents an innovative application of Structural Equation Modelling (SEM) within the framework of the International Classification of Functioning, Disability and Health (ICF) for CTS patients. Purpose: The aim of this study was to examine the effects of symptoms, proprioception, electrodiagnostic findings, and activity/participation in idiopathic CTS. Methods: This cross-sectional study included 81 patients with mild to moderate idiopathic CTS. For the assessment of body structure/function, symptoms were measured by Visual Analogue Scale, Leeds Assessment of Neuropathic Symptoms and Signs, and Boston Carpal Tunnel Questionnaire–Symptom Severity Scale; proprioception by the force reproduction tests; and electrodiagnostic findings. Activity/participation were assessed using the Boston Carpal Tunnel Questionnaire–Functional Status Scale and the Quick Disability of the Arm, Shoulder, and Hand. SEM was used to examine the effect of body structure/function on activity/participation. Results: This study revealed that symptoms (standardized coefficient = 0.858, p <.001) and proprioception (0.207, p =.032) had a significant effect on activity/participation. Conversely, the model results indicated no significant effect of sensory nerve conduction findings (−0.031, p =.673) and motor nerve conduction findings (0.195, p =.170) on activity/participation. Conclusion: Relying solely on electrodiagnostic findings may contribute to the underestimation or misinterpretation of activity/participation limitations in patients with CTS. The findings of this study suggest that reducing symptoms may enhance activity/participation. Incorporating proprioception into the management of CTS patients may offer promising benefits
LAPAROSCOPIC EXCISION OF AN ACCESSORY CAVITATED UTERINE MALFORMATION IN AN ADOLESCENT PATIENT
No full textObjectiveTo demonstrate the laparoscopic, uterus-sparing excision of an accessory cavitated uterine malformation (ACUM) in an adolescent patient and to emphasize the importance of accurate preoperative imaging for intraoperative localization.SettingTertiary referral center for minimally invasive gynecologic surgery.ParticipantsAn 18-year-old adolescent patient presenting with severe dysmenorrhea and chronic pelvic pain refractory to medical treatment.InterventionsLaparoscopic excision of a noncommunicating accessory cavitated uterine lesion with preservation of the main uterine cavity.ConclusionPreoperative transabdominal ultrasonography and magnetic resonance imaging demonstrated a 35 × 43 mm cystic lesion located in the left anterior uterine wall, clearly separated from the endometrial cavity and consistent with ACUM. During laparoscopy, no obvious uterine bulging was observed, making intraoperative localization challenging. A targeted myometrial incision allowed identification and complete excision of the lesion, which contained chocolate-colored fluid and was lined with endometrium-like tissue. The main uterine cavity was preserved, and layered myometrial reconstruction was performed. Histopathological examination confirmed the diagnosis of ACUM. Laparoscopic uterus-sparing excision is a safe and effective treatment option for adolescent patients with ACUM when guided by accurate preoperative imaging.</div
Multifactorial protective effects of boric acid against postoperative intra-abdominal adhesions in a rat model
No full textPostoperative intra-abdominal adhesions (IAAs) remain a significant clinical challenge, contributing to complications such as bowel obstruction, infertility, and chronic pain. This study investigated the therapeutic potential of boric acid (BA) in mitigating adhesion formation through its antioxidative, anti-inflammatory, anti-apoptotic, and anti-fibrotic properties. A total of Twenty-four adult male Sprague Dawley rats were randomly divided into three groups: Control, IAA (adhesion model), and IAA+BA (adhesion model treated with boric acid). The main indicators of adhesion severity—macroscopic adhesion score, histopathological fibrosis and inflammation grades, and systemic TGF-β1 levels—were markedly improved in the IAA+BA group compared with the untreated IAA group, indicating a clear reduction in adhesion formation and fibrotic progression. In parallel, supporting mechanistic readouts showed that BA significantly modulated oxidative stress (TAS, TOS, OSI), pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, CRP), and apoptotic markers (CASP3, CYCS, Bcl-2). BA effectively suppressed CASP3 and CYCS while restoring Bcl-2 expression, suggesting reduced apoptotic activity. These preliminary findings demonstrate that BA exerts anti-adhesive effects through a multifactorial mechanism involving the regulation of oxidative stress, inflammation, apoptosis, and fibrosis. Collectively, the data highlight BA's promise as a safe and potentially effective adjunctive therapy for preventing IAAs in postoperative settings
The Urostomy Care Skills Evaluation Tool: A scale development study
No full textAimThis study was designed and implemented to develop a tool for evaluating the steps involved in urostomy care.BackgroundProviding effective urostomy care requires the acquisition of specific clinical skills. However, nursing education lacks standardized tools to assess these skills.DesignMethodological study.MethodThis research was conducted at a nursing faculty in Istanbul from May–June 2023. The sample consisted of 140 nursing student enrolled in a surgical nursing course who met the inclusion criteria. Data for the study were collected via the “Personal Information Form,” which consists of 10 questions about individual characteristics such as age, gender, academic performance and perspectives on the nursing profession and the “Urostomy Care Skills Evaluation Tool,” a 28-step tool developed on the basis of the literature.ResultsAfter the items for the evaluation tool were created, feedback was obtained from 10 experts and the content validity index was found to be sufficient (CVI: 0.978). The consistency among independent observers evaluating the tool’s items was statistically significant and high (ICC: 0.995; p < 0.001). The testretest reliability of the tool also showed high consistency.ConclusionThe Urostomy Care Skills Evaluation Tool provides initial evidence of content validity and reliability for assessing urostomy care performance among nursing students in a simulation-based educational setting. The tool appears useful for evaluating training outcomes in undergraduate nursing education. However, further validation studies conducted in clinical settings and involving practicing nurses and caregivers are needed before broader applicability can be established.AimThis study was designed and implemented to develop a tool for evaluating the steps involved in urostomy care.BackgroundProviding effective urostomy care requires the acquisition of specific clinical skills. However, nursing education lacks standardized tools to assess these skills.DesignMethodological study.MethodThis research was conducted at a nursing faculty in Istanbul from May–June 2023. The sample consisted of 140 nursing student enrolled in a surgical nursing course who met the inclusion criteria. Data for the study were collected via the “Personal Information Form,” which consists of 10 questions about individual characteristics such as age, gender, academic performance and perspectives on the nursing profession and the “Urostomy Care Skills Evaluation Tool,” a 28-step tool developed on the basis of the literature.ResultsAfter the items for the evaluation tool were created, feedback was obtained from 10 experts and the content validity index was found to be sufficient (CVI: 0.978). The consistency among independent observers evaluating the tool’s items was statistically significant and high (ICC: 0.995; p < 0.001). The testretest reliability of the tool also showed high consistency.ConclusionThe Urostomy Care Skills Evaluation Tool provides initial evidence of content validity and reliability for assessing urostomy care performance among nursing students in a simulation-based educational setting. The tool appears useful for evaluating training outcomes in undergraduate nursing education. However, further validation studies conducted in clinical settings and involving practicing nurses and caregivers are needed before broader applicability can be established.</div
The effect of breastfeeding experience presented with virtual reality on breastfeeding self-efficacy and breastfeeding motivation: a randomized controlled trial
No full textObjective: To examine the impact of the virtual reality breastfeeding experience on prenatal breastfeeding self-efficacy and postpartum breastfeeding motivation among primiparous pregnant women. Methods: This study was conducted as a prospective randomized controlled trial. Both groups received standard breastfeeding education; however, the study group additionally participated in a virtual reality breastfeeding experience at 36 and 38 weeks of gestation. Data were collected using the Personal Information Form, the Prenatal Breastfeeding Self-Efficacy Scale, and the Breastfeeding Motivation Scale. Results: A total of 52 primiparous pregnant women, 26 in the study group and 26 in the control group, were included in the study. Women in the study group exhibited higher prenatal breastfeeding self-efficacy and greater postpartum breastfeeding motivation compared to those in the control group. Additionally, postpartum breastfeeding motivation increased as prenatal breastfeeding self-efficacy improved. Conclusion: Breastfeeding experience with virtual reality is associated with higher prenatal breastfeeding self-efficacy and postpartum breastfeeding motivation in women
Pilot analysis of Chitinase-3-like protein 1 and soluble Syndecan-1 CSF levels as potential biomarkers in relapsing-remitting multiple sclerosis
No full textBackground Chitinase-3-like protein 1 (CHI3L1), secreted by immune cells, plays a key role in modulating immune responses. Syndecan-1 (SDC-1), a cell surface heparan sulfate proteoglycan, is involved in the regulation of inflammation. This study aimed to evaluate whether CHI3L1 and soluble SDC-1 (sSDC-1) act as potential diagnostic targets in patients with relapsing-remitting multiple sclerosis (RRMS). Methods sSDC-1 and CHI3L1 levels were quantified using enzyme-linked immunosorbent assay (ELISA) in cerebrospinal fluid (CSF) samples collected from a cohort of 39 newly diagnosed patients with relapsing-remitting multiple sclerosis (RRMS) and 32 disease controls diagnosed with idiopathic intracranial hypertension (IIH). Results No significant difference was observed in CSF sSDC-1 levels between the RRMS and IIH groups. However, CSF CHI3L1 levels were significantly lower in patients with RRMS compared to those with IIH. Conclusion The present findings do not provide clear evidence supporting a diagnostic role for CSF levels of sSDC-1 or CHI3L1 in MS
Characterization and photodiode applications of henna solution dissolved in methanol and of metal lawsonate complexes synthesized using this solution
No full textFirstly, henna solution was prepared and characterized by FTIR spectrum. Using this solution containing lawsone, Pb(Law)2 and Cu(Law)2 complexes were synthesized and then these complexes were characterized by FTIR and mass spectra and elemental analysis. The henna solution and solutions of metal complexes dissolved in N,N-dimethylformamide (DMF) were used as interface layers in making three different photodiodes. Necessary graphs were drawn using the I–V, C–V, and (G/ω)–V measurement values taken for the photodiodes made and then the necessary parameters were calculated from these graphs. It was observed that Al/Pb(Law)2/p-Si photodiode was more ideal than Al/Henna/p-Si and Al/Cu(Law)2/p-Si photodiodes in the dark. Moreover, it was seen that as the illumination intensity increased, the Al/Pb(Law)2/p-Si and Al/Cu(Law)2/p-Si photodiodes moved away from ideality and that the Al/Pb(Law)2/p-Si photodiode was more ideal than the Al/Cu(Law)2/p-Si photodiode under all illumination intensities studied, provided that the illumination intensity was the same
Geriatric Assessment in Older Patients with A Hematologic Malignancy: Frailty, Urinary incontinence and Nutrition
No full textBackground: The study aimed to evaluate geriatric hematology patients in terms of geriatric syndromes, to provide the most appropriate individualized care and practices in the treatment processes, to access sufficient information about the patient and to contribute to the literature that geriatric hematology patients may be in the risk group in terms of geriatric syndromes. Methods: In the study, the data were evaluated with urinary incontinence severity scale, mini nutritional analysis, Edmonton Frailty scale and an introductory information form created by the researchers. Results: More than half of the geriatric individuals included in the study were diagnosed with leukemia. They had at least one chronic disease other than their hematological diseases, the average age was 70, more than half of them were frail, their MNA average was within the malnutrition risk limits, they were independent according to their average scores on Katz ADL. It was also determined that the participants were in the moderate incontinence range. Conclusion: Elderly individuals with hematological malignancies should be considered for geriatric evaluation throughout treatment. Geriatric evaluation is important to prevent possible complications during treatment and improve quality of life
