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Transplantation of iPS-derived Vascular Endothelial Cells Improves White Matter Ischemic Damage
No full text群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1818doctoral thesi
Human Factors Affecting the Frequency of Incidents by Years of Nursing Experience: Analysis of Acute Care Hospital Nurses of Regional Cities in Japan
No full textJournal ArticleBackground & Aims: Medical safety measures for nurses are an important issue. The present study aimed to clarify the human factors affecting the frequency of incidents by years of experience.
Methods: The participants were 1,489 nurses working in acute care hospitals with more than 400 beds. An anonymous, self-administered questionnaire survey was conducted. The survey included the frequency of incidents in the last six months and a “Questionnaire on Work Situations Commonly Associated with Nursing-Related Incidents.” Multiple logistic regression analysis was performed. Explanatory variables were extracted from the questionnaire items through principal component analysis. The objective variable was incident frequency. The analysis was conducted by years of experience.
Results: Valid responses were obtained from 716 nurses. Extracted variables were: unsafe execution of work, psychological stress, physical stress, busy work environment. Significant associations with incident frequency was found for busy work environment, psychological stress, and unsafe execution of work for nurses with up to 1 year, 4-10 years, and 11 or more years of experience, respectively.
Conclusion: The human factors affecting incident frequency were shown to differ depending on the nurses’ years of experience. Thus, preventive measures based on nursing experience are necessary: improving support systems to reduce busyness, improve psychological support, and address role familiarity for nurses with up to 1 year, 4-10 years, and 11 or more years of experience, respectively.journal articl
Surgical Revascularization for Internal Carotid Artery Stenosis in the Acute Stage of Cerebral Infarction
No full textJournal Article【目 的】 脳梗塞急性期に施行した頚部内頚動脈外科的血行再建術の特徴，治療成績を評価し，治療方針の妥当性について検証する．
【対 象】 2016年10月～2019年9月の間，頚動脈内膜剥離術（carotid endarterectomy：CEA），頚動脈ステント留置術（carotid artery stenting：CAS）を施行した頚動脈狭窄症連続30例を後方視的に調査した．
【方 法】 最終脳虚血イベントより14日以内を急性期と定義，非急性期群と比較検討した．2群間での患者背景，術前画像所見，病理所見（CEAのみ），合併症，転帰につき調査した．
【結 果】 急性期群は9例（CEA4例，CAS5例），非急性期群は21例（CEA10例，CAS11例）であった．術前画像所見に両群で有意差はなかった．永続的合併症，治療30日以内の同側脳卒中再発，虚血性心疾患発症は両群で認めず，治療30日後のmodified Rankin Scale（mRS）0─2の割合は急性期群で3例（33％），非急性期群で16例（76％）であった（P<0.05）．全30症例でCEA施行群ではCAS施行群よりも有意にプラーク体積が大きく（CEA：1,090 mm2 CAS：612 mm2 P<0.01），急性期CEA，CAS間でも同様の傾向であった．
【結 論】 本シリーズでは脳梗塞急性期におけるCEA，CASの施行に際し，周術期脳梗塞，過潅流症候群，出血性梗塞を含めた重篤な合併症はなかった．journal articl
A Case of Pneumaturia Due to Gas Production in the Bladder
No full textJournal ArticleWe report the case of a 60-year-old man with pneumaturia due to gas production by Klebsiella pneumoniae in the bladder. Diabetes mellitus is a major risk factor, and K. pneumoniae produces carbon dioxide by fermenting glucose under anaerobic conditions. Antibiotic therapy successfully improved cystitis and pneumaturia. However, in the presence of urinary tract obstruction and/or emphysematous upper urinary tract infections, other interventions may be needed.journal articl
Enhanced closed-state inactivation of mutant cardiac sodium channels (SCN5A N1541D and R1632C) through different mechanisms
Get PDF群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1770doctoral thesi
In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice
Get PDF群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1772doctoral thesi