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豊富な粘液様間質を伴った腎盂尿路上皮癌の一例 尿細胞診における泡沫状細胞の意義
背景:尿中に泡沫状の細胞が出現した場合、通常はマクロファージや淡明細胞型腎細胞癌(clearcell renal cell carcinoma:以下RCC)や空胞変性した尿路上皮細胞、尿細管上皮細胞等の良性細胞との鑑別が必要となるが、今回我々は異型の乏しい泡沫状の腎盂尿路上皮癌細胞が出現する症例を経験したので報告する。症例:70代、女性。腹部超音波検査、造影CT等よりRCCを疑われたが、腎盂尿路上皮癌との鑑別のために尿細胞診(自然尿)が提出された。顕微鏡的血尿と多数の細菌、炎症を背景に、泡沫状の細胞を認めた。RCCの可能性があるものの、異型に乏しく、鑑別困難と判定した。後日、腎盂尿管全摘術が施行された。左腎盂から腎盂尿管移行部にかけて広範囲に乳頭状隆起性腫瘍が認められた。組織学的に豊富な粘液様間質を伴った浸潤性腎盂尿路上皮癌を観察し、PAS染色、Alcian blue染色陽性であった。また、同間質に浮遊する様に泡沫状の腎盂尿路上皮癌細胞を確認した。結論:「豊富な粘液様間質を伴う浸潤性腎盂尿路上皮癌」では、尿中にAlcian blue陽性を示す、異型の乏しい泡沫状の腎盂尿路上皮癌細胞が出現する
スクワット運動における圧中心の移動による筋活動パターン
The squat exercise is a fundamental movement in athletic training and rehabilitation. In this study, we measured muscle activities in a normal squat posture (NSP) and a squat posture with the center of foot pressure (COP) intentionally shifted forward as far as possible (FSP). Ten healthy men performed double-limb squats, adopting the NSP and FSP, with three knee flexion angles (30, 60, and 90 degrees). The muscle activities of the vastus medialis (VM), semitendinosus (ST), tibialis anterior (TA), and gastrocnemius muscle lateral head (GL) were measured using surface electromyography, and activity patterns were analyzed. Compared to that for the NSP, the COP was significantly shifted forward in the FSP by at least 30% of the foot length for all knee flexion angles (p < 0.05). At all knee flexion angles, VM muscle activity significantly decreased, while GL muscle activity increased, in the FSP compared to that for the NSP (p < 0.05). In addition, ST muscle activity increased significantly in the FSP compared to that for the NSP at knee flexion angles of 30 and 60 degrees (p < 0.05). TA muscle activity significantly decreased in the FSP compared to that for the NSP at only 90 degrees of knee flexion (p < 0.05). These results demonstrate that muscle activity patterns vary significantly according to squat posture. Thus, the active control of the COP position during the squat can be a new training approach in targeting specific muscle groups.博士(医学)・甲第723号・令和元年12月5日©Journal of Sports Science and Medicine (2019)This work is licensed under a Creative Commons License CreativeCommons Attribution-NonCommercial-NoDerivatives 4.0 International License(https://creativecommons.org/licenses/by-nc-nd/4.0/
A New Minimally Invasive Technique of Combined Chest Wall Resection for Lung Cancer : Advanced Data of Implication of Advanced Bipolar Device in Video-Assisted Chest Wall Resection for Lung Cancer.
We describe a novel method for resecting lung cancer that has invaded the chest wall
using an advanced bipolar device during video-assisted thoracoscopic surgery. The method is convenient for both tumor and chest wall resection because it is easy to handle and less invasive than the currently used technique