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An epidemiologic study of physician-diagnosed chronic obstructive pulmonary disease in the Turkish population: COPDTURKEY-1
No full textA premature infant with bilateral corneal ulceration due to Vitamin A deficiency [Prematür Bebekte Vitamin A Eksikliğine Bağlı Bilateral Kornea Ülseri]
No full textIs iliac autogenous graft augmentation in medial open wedge high tibial osteotomies superior to no augmentation in terms of bone healing?
No full textA novel deep learning algorithm for the automatic detection of high-grade gliomas on T2-weighted magnetic resonance images: A preliminary machine learning study
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Prevalence of diversified antibiotic resistant bacteria within sanitation related facilities of human populated workplaces in Abbottabad
No full textAntibiotics discovery was a significant breakthrough in the field of
therapeutic medicines, but the over (mis)use of such antibiotics (in
parallel) caused the increasing number of resistant bacterial species at
an ever-higher rate. This study was thus devised to assess the
multi-drug resistant bacteria present in sanitation-related facilities
in human workplaces. In this regard, samples were collected from
different gender, location, and source-based facilities, and subsequent
antibiotic sensitivity testing was performed on isolated bacterial
strains. Four classes of the most commonly used antibiotics i.e.,
beta-lactam, Aminoglycosides, Macrolides, and Sulphonamides, were
evaluated against the isolated bacteria. The antibiotic resistance
profile of different (70) bacterial strains showed that the antibiotic
resistance-based clusters also followed the grouping based on their
isolation sources, mainly the gender. Twenty-three bacterial strains
were further selected for their 16s rRNA gene based molecular
identification and for phylogenetic analysis to evaluate the taxonomic
evolution of antibiotic resistant bacteria (ARB). Moreover, the
bacterial resistance to Sulphonamides and beta lactam was observed to be
the most and to Aminoglycosides and macrolides as the least. Plasmid
curing was also performed for multidrug resistant (MDR) bacterial
strains, which significantly abolished the resistance potential of
bacterial strains for different antibiotics. These curing results
suggested that the antibiotic resistance determinants in these purified
bacterial strains are present on respective plasmids. Altogether, the
data suggested that the human workplaces are the hotspot for the
prevalence of MDR bacteria and thus may serve as the source of
horizontal gene transfer and further transmission to other environments
Fumigant toxicity of essential oil of Hypericum perforatum L., 1753 (Malpighiales: Hypericaceae) to Tenebrio molitor L., 1758 (Coleoptera: Tenebrionidae)
No full textIn this study, vapor of essential oil obtained by the hydrodistillation
of Hypericum perforatum L., 1753 (Malpighiales: Hypericaceae) was tested
on the different stages of Tenebrio molitor L., 1758 (Coleoptera:
Tenebrionidae). The larvae, pupae and adult stages of T. molitor were
exposed to different doses of H. perforatum essential oil for 24 h.
After exposure, mortality rate, LC50, LC90 and LC99 values, antioxidant
enzyme activities {[}superoxide dismutase (SOD), catalase (CAT),
glutathione-S-transferase (GST) and glutathione peroxidase (GPx)],
acetylcholinesterase (AChE) activity and malondialdehyde (MDA) levels
were measured in the insects. Tenebrio molitor was cultured at Gazi
University Department of Biology and all analyses were done in Yozgat
Bozok University in 2017 and 2018. The results indicated that the pupae
of T. molitor were the most tolerant and adults were the most sensitive.
Mortality increased with the increasing concentration of essential oil.
Also, increasing doses of essential oil caused decreasing in SOD, CAT,
GST GPx and AChE activities and increasing in MDA level. These results
indicate that essential oil of H. perforatum can be used against T.
molitor in a pest control program
